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cell culture

Organ-on-a-chip: a New Model of Microfluidic Chip

April 22, 2018

Cells in a microwell and their growth after two days of perfusion  An organ-on-a-chip is a microfluidic device with continuously perfused chambers in which cells are cultured to obtain functional units that mimic organ functions. The [more...]

Adding Depth to Cell Culture

June 18, 2017

As a postdoc studying human brain development and what goes wrong in conditions such as microencephaly, Madeline Lancaster faced the same familiar problems as her fellow lab researchers. For example, mice brains don’t behave or develop [more...]

3-D Model of Human Brain Development and Disease

May 13, 2017

After spheroids representing two different brain regions fuse in a dish, neurons from one spheroid (green) migrate into the other and forge connections with the neurons there. (Image Credit: Pasca lab, Stanford University) Brain [more...]

Microfluidic Cell Culture

July 20, 2016

Microfluidics Microfluidics technology is characterized by the manipulation of small volumes of fluids (10-9 to 10-18 liters) in channels with dimensions of tens of micrometers. Certain properties of microfluidic technologies such as rapid [more...]

Capturing Cell Growth in 3D with Microfluidic Device

August 15, 2015

AIM Biotech’s microfluidics device (shown here) has an array of culturing sections, each with three chambers: a middle chamber for hydrogel and any cell type, and two side channels for culturing additional cell types. Replicating how [more...]

Microfluidics’ Watershed Moment

June 28, 2015

The HµRELflow™ cell-based assay system has three microfluidic devices on a biochip. Each device incorporates two cell culture compartments interconnected by microscale channels. Integrated micropumps recirculate culture media within the [more...]

Nanofiber Band-Aid for Broken Hearts

June 21, 2015

Immunofluorescence image showing expression of cardiomyocyte marker α-sarcomeric actinin (green color); Nuclei (blue color); and Aligned nanofiber (red Color) in the cardiac patch in vitro. (Image credit: Ohio State University Center for [more...]

Microfluidics for Accelerated Drug Assays

April 12, 2015

Multiple microwells on Yevgeny Berdichevsky’s assay chips make it possible to test up to 18 drug candidates at a time. (Image Credit: Linda Nye) Approximately 125,000 Americans each year develop epilepsy, a brain disease marked by [more...]
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