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RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • Non-planar PDMS microfluidic channels and actuators: a review
    by Yongha Hwang on August 17, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00523G, Critical ReviewYongha Hwang, Robert CandlerThis review examines state of the art for manufacturing non-planar miniature channels and actuators from PDMS, where non-planar structures are defined here as those beyond simple extrusions of 2D designs,...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic device for rapid digestion of tissues into cellular suspensions
    by Xiaolong Qiu on August 16, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00575J, PaperXiaolong Qiu, Trisha Westerhof, Amrith Karunaratne, Erik Werner, Pedram Pourfard, Edward Nelson, Elliot E Hui, Jered Brackston HaunThe ability to harvest single cells from tissues is currently a bottleneck for cell-based diagnostic technologies, and remains crucial in the fields of tissue engineering and regenerative medicine. Tissues are...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Vessel-on-a-chip models for drug delivery
    by David Caballero on August 16, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00574A, Critical ReviewDavid Caballero, Sophie M Blackburn, Mar de Pablo, Josep Samitier, Lorenzo AlbertazziNanocarriers for drug delivery hold great potential to revolutionize cancer treatment, thanks to their enhanced selectivity and efficacy. Despite this great promise, researchers have had limited success in the clinical...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Reply to the 'Comment on "Towards a personalized approach to aromatase inhibitor therapy: a digital microfluidic platform for rapid analysis of estradiol in core-needle-biopsies"' by P. E. Lonning, Lab Chip, 2017, 17, DOI: 10.1039/C7LC00617A
    by Robert F. Casper on August 16, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00751E, CommentRobert F. Casper, Aaron R. WheelerThis article provides our response to a comment on our article that appeared in Lab on a Chip.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Comment on "Towards a personalized approach to aromatase inhibitor therapy: a digital microfluidic platform for rapid analysis of estradiol in core-needle-biopsies" by S. Abdulwahab, A. H. C. Ng, M. D. Chamberlain, H. Ahmado, L.-A. Behan, H. Gomaa, R. F. Casper and A. R. Wheeler, Lab Chip, 2017, 17, 1594
    by Per E. Lonning on August 16, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00617A, CommentPer E. LonningThis comment on an article that appeared in Lab on a Chip highlights the need for further validation of the proposed method.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Enabling miniaturised personalised diagnostics: From lab-on-a-chip to lab-in-a-drop
    by Kevin Koo on August 15, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00587C, Critical ReviewKevin Koo, Eugene J. H. Wee, Yuling Wang, Matt TrauThe concept of personalised diagnostics is to direct accurate clinical decisions based on an individual's unique disease molecular profile. Lab-on-a-chip (LOC) systems are prime personalised diagnostics examples which seek to...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A Microfluidic Platform for the High-throughput Study of Pathologic Cardiac Hypertrophy
    by Hesam Parsa on August 15, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00415J, PaperHesam Parsa, Bryan Z Wang, Gordana Vunjak-NovakovicCurrent in vitro models fall short in deciphering the mechanisms of cardiac hypertrophy induced by volume overload. We developed a pneumatic microfluidic platform for high-throughput studies of cardiac hypertrophy that...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic systems for high-throughput and high-content screening using the nematode Caenorhabditis elegans
    by Matteo Cornaglia on August 14, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00509A, Critical ReviewMatteo Cornaglia, Thomas Lehnert, Martin GijsIn a typical high-throughput drug screening (HTS) process, up to millions of chemical compounds are applied to cells cultured in well plates, aiming to find molecules that exhibit a robust...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Native extracellular matrix-derived semipermeable, optically transparent, and inexpensive membrane inserts for microfluidic cell culture
    by Mark J. Mondrinos on August 14, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00317J, PaperMark J. Mondrinos, Yoon-Suk Yi, Nan-Kun Wu, Xueting Ding, Dongeun HuhThis paper presents a new type of cell culture membranes engineered from native extracellular matrix (ECM) materials that are thin, semipermeable, optically transparent, and amenable to integration into microfluidic cell culture devices.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Asymmetric motion of magnetically actuated artificial cilia
    by Srinivas Hanasoge on August 13, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00556C, PaperSrinivas Hanasoge, Matthew Ballard, Peter J. Hesketh, Alexander AlexeevWe demonstrate magnetically actuated synthetic cilia that exhibit biomimetic asymmetric beating.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Vacuum filling of complex microchannels with liquid metal
    by Yiliang Lin on August 13, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00426E, CommunicationYiliang Lin, Olivia Gordon, M. Rashed Khan, Neyanel Vasquez, Jan Genzer, Michael D. DickeyThis paper describes the utilization of vacuum to fill complex microchannels with liquid metal.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Trapping and Patterning of Large Particles and Cells in a 1D Ultrasonic Standing waves
    by Ruhollah Habibi on August 13, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00640C, PaperRuhollah Habibi, Citsabehsan Devendran, Adrian NeildThe use of ultrasound for trapping and patterning particles or cells in microfluidic systems is usually confined to particles which are considerably smaller than that of the acoustic wavelength. In...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Chip-scale alignment of long DNA nanofibers on a patterned self-assembled monolayer
    by J. Xia on August 10, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00676D, CommunicationJ. Xia, M. SuCentimeter-long genomic DNA nanofibers produced by the interplay between surface tension and electrostatic force of micro-patterns.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Droplet microfluidics for synthetic biology
    by Philip C. Gach on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00576H, Critical ReviewPhilip C. Gach, Kosuke Iwai, Peter W. Kim, Nathan J. Hillson, Anup K. SinghReview of current droplet microfluidics systems as they apply to the field of synthetic biology and genetic engineering.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A switchable 3D liquid-liquid biconvex lens with enhanced resolution by Dean flows
    by Li Liang on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00598A, PaperLi Liang, Xiaoqiang Zhu, Hailiang Liu, Yang Shi, Yi YangLiquid- liquid (L2) microlenses have great potential in various applications of imaging and detection systems. Traditional ones are almost two dimensions (2D) in shape as the modulation of flow rates...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Tissue chips - innovative tools for drug development and disease modeling
    by L. A. Low on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00462A, Critical ReviewL. A. Low, D. A. TagleThe high rate of failure during drug development is well-known, however recent advances in tissue engineering and microfabrication have contributed to the development of microphysiological systems (MPS), or 'organs-on-chips' that recapitulate the function of human organs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Magnetic particles assisted capture and release of rare tumor cells using wavy-herringbone structured microfluidic devices
    by Wentao Shi on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00333A, PaperWentao Shi, shunqiang Wang, Ahmad Maarouf, Christopher G Uhl, Ran He, Doruk Yunus, Yaling LiuA wavy-herringbone (wavy-HB) structured microfluidic device was used to effectively and selectively capture and release circulating tumor cells (CTCs) by using immunoaffinity and magnetic force. The device was designed to...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Fluorescence activated cell sorting via a focused traveling surface acoustic beam
    by Zhichao Ma on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00678K, PaperZhichao Ma, Yinning Zhou, David J. Collins, Ye AiFluorescence activated sorting at the single cell level using a highly focused traveling surface acoustic wave beam ([similar]50 [small mu ]m).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microparticle parking and isolation for highly sensitive microRNA detection
    by Jae Jung Kim on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00653E, PaperJae Jung Kim, Lynna Chen, Patrick S. DoyleWe demonstrate a microfluidic platform that immobilizes hydrogel microparticles at defined locations, and encapsulates particles in monodisperse droplets for sensitive bioassays.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidics for exosome isolation and analysis: Enabling liquid biopsy for personalized medicine
    by Jose C. Contreras-Naranjo on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00592J, Critical ReviewJose C. Contreras-Naranjo, Hung-Jen Wu, Victor M. UgazExosomes, the smallest sized extracellular vesicles (30 ~ 150 nm) packaged with lipids, proteins, functional messenger RNAs and microRNAs, and double-stranded DNA from their cells of origin, have emerged as...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Point-of-Care Diagnostics to Improve Maternal and Neonatal Health in Low-Resource Settings
    by Catherine E Majors on August 9, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00374A, Critical ReviewCatherine E Majors, Chelsey A. Smith, Mary E. Natoli, Kathryn A. Kundrod, Rebecca Richards-KortumEach day, approximately 830 women and 7,400 newborns die from complications during pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid diagnosis and treatment to the point...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A magnetic micropore chip for rapid (<1 hour) unbiased circulating tumor cell isolation and in situ RNA analysis
    by Jina Ko on August 8, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00703E, PaperJina Ko, Neha Bhagwat, Stephanie S. Yee, Taylor Black, Colleen Redlinger, Janae Romeo, Mark O'Hara, Arjun Raj, Erica L. Carpenter, Ben Z. Stanger, David IssadoreWe have developed a microchip platform that combines fast, magnetic micropore based negative selection (>10 mL h-1) with rapid on-chip in situ RNA profiling.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multiplex coaxial flow focusing for producing multicompartment Janus microcapsules with tunable material compositions and structural characteristics
    by Qiang Wu on August 8, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00769H, PaperQiang Wu, Chaoyu Yang, Guangli Liu, Wanghuai Xu, Zhiqiang Zhu, Ting Si, Ronald X. XuWe propose a simple but efficient multiplex coaxial flow focusing (MCFF) process for single-step fabrication of multicompartment Janus microcapsules (MJMs) in a wide range of operating parameters.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multivesicular droplets: a cell model system to study compartmentalised biochemical reactions
    by N. Nuti on August 7, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00710H, PaperN. Nuti, P. E. Verboket, P. S. DittrichWe present a droplet-based microfluidic device for the generation of Multivesicular droplets (MVDs). This novel system serves as a platform to study the compartmentalisation of cells and as a scaffold for the construction of artificial cell/protocell models.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic co-flow of Newtonian and viscoelastic fluids for high-resolution separation of microparticles
    by Fei Tian on August 6, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00671C, PaperFei Tian, Wei Zhang, Lili Cai, Shanshan Li, Guoqing Hu, Yulong Cong, Chao Liu, Tiejun Li, Jiashu SunA microfluidic co-flow of Newtonian (water or PBS) and viscoelastic fluids (PEO) is presented for the size-dependent separation of microparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Interfacial-entropy-driven thermophoretic tweezers
    by Linhan Lin on August 3, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00432J, PaperLinhan Lin, Xiaolei Peng, Zhangming Mao, Xiaoling Wei, Chong Xie, Yuebing ZhengA new type of interfacial-entropy-driven thermophoretic tweezers is demonstrated for versatile particle manipulation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Label-free ferrohydrodynamic cell separation of circulating tumor cells
    by Wujun Zhao on August 3, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00680B, PaperWujun Zhao, Rui Cheng, Brittany D. Jenkins, Taotao Zhu, Nneoma E. Okonkwo, Courtney E. Jones, Melissa B. Davis, Sravan K. Kavuri, Zhonglin Hao, Carsten Schroeder, Leidong MaoA size-based ferrohydrodynamic cell separation (FCS) device capable of enriching intact circulating tumor cells with high throughput and high recovery rate.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Flash crystallization kinetics of methane (sI) hydrate in a thermoelectrically-cooled microreactor
    by Weiqi Chen on August 2, 2017 at 11:00 pm

    Lab Chip, 2017, Accepted ManuscriptDOI: 10.1039/C7LC00645D, PaperWeiqi Chen, Bruno Pinho, Ryan L HartmanThe crystallization kinetics of methane (sI) hydrate were investigated in thermoelectrically-cooled microreactor with in situ Raman spectroscopy. Step-wise and precise control of the temperature allowed acquisition of reproducible data within...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic modeling of the biophysical microenvironment in tumor cell invasion
    by Yu Ling Huang on August 2, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00623C, PerspectiveYu Ling Huang, Jeffrey E. Segall, Mingming WuMicrofluidic model for the physical tumor microenvironment: intramural and interstitial flows and extracellular matrices (ECMs).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Large-scale, all polycrystalline diamond structures transferred onto flexible Parylene-C films for neurotransmitter sensing
    by Bin Fan on August 2, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00229G, PaperBin Fan, Yan Zhu, Robert Rechenberg, Cory A. Rusinek, Michael F. Becker, Wen LiThis paper presents a wafer-level fabrication technique capable of transferring multi-scale boron-doped diamond patterns from a rigid silicon substrate onto a Parylene-C substrate to achieve flexible diamond electrochemical sensors for neurotransmitter detection.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Plant array chip for the germination and growth screening of Arabidopsis thaliana
    by Youn-Hee Park on August 2, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00463J, PaperYoun-Hee Park, Nayoung Lee, Giltsu Choi, Je-Kyun ParkA plant array chip for Arabidopsis thaliana contributes to more efficient screening of the essential phenotype such as germination and growth.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Cell-free extract based optimization of biomolecular circuits with droplet microfluidics
    by Yutaka Hori on August 2, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00552K, CommunicationYutaka Hori, Chaitanya Kantak, Richard M. Murray, Adam R. AbateWe combine cell-free protein expression systems with droplet microfluidics to enable ultrahigh-throughput parameter space exploration of synthetic biocircuits.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A microfluidic flow cytometer enabling absolute quantification of single-cell intracellular proteins
    by Xiufeng Li on August 1, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00546F, PaperXiufeng Li, Beiyuan Fan, Shanshan Cao, Deyong Chen, Xiaoting Zhao, Dong Men, Wentao Yue, Junbo Wang, Jian ChenThis paper presents a constriction channel based microfluidic flow cytometer enabling absolute quantification of single-cell intracellular proteins.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Droplet trapping and fast acoustic release in a multi-height device with steady-state flow
    by Richard W. Rambach on August 1, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00378A, PaperRichard W. Rambach, Kevin Linder, Michael Heymann, Thomas FrankeNovel multilayer PDMS device for selective storage and release of single emulsion droplets via surface acoustic waves at constant flow with a high drop rate.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Biocompatible 3D printed polymers via fused deposition modelling direct C2C12 cellular phenotype in vitro
    by Rowan P. Rimington on July 31, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00577F, PaperRowan P. Rimington, Andrew J. Capel, Steven D. R. Christie, Mark P. LewisThis research demonstrates biocompatible 3D printed polymers that are capable of controlling skeletal muscle cellular phenotype in vitro.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic platform for efficient Nanodisc assembly, membrane protein incorporation, and purification
    by James H. Wade on July 25, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00601B, PaperJames H. Wade, Joshua D. Jones, Ivan L. Lenov, Colleen M. Riordan, Stephen G. Sligar, Ryan C. BaileyA microfluidic platform for Nanodisc formation and membrane protein incorporation will enable studies of interactions at model membrane interfaces.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multimode smartphone biosensing: the transmission, reflection, and intensity spectral (TRI)-analyzer
    by Kenneth D. Long on July 23, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00633K, PaperKenneth D. Long, Elizabeth V. Woodburn, Huy M. Le, Utsav K. Shah, Steven S. Lumetta, Brian T. CunninghamThis low-cost, smartphone-based spectral TRI-analyzer system performs three classes of optical biosensing techniques and is compared with two commercially-available assays.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Nanofluidic crystals: nanofluidics in a close-packed nanoparticle array
    by Wei Ouyang on July 19, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00588A, Tutorial ReviewWei Ouyang, Jongyoon Han, Wei WangNanofluidic crystals bridge nanofluidic concepts with real-world applications in various fields.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • In situ generation of human brain organoids on a micropillar array
    by Yujuan Zhu on July 19, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00682A, PaperYujuan Zhu, Li Wang, Hao Yu, Fangchao Yin, Yaqing Wang, Haitao Liu, Lei Jiang, Jianhua QinWe present a simple and high throughput manner to generate brain organoids in situ from human induced pluripotent stem cells on micropillar arrays and to investigate long-term brain organogenesis in 3D culture in vitro.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Robust manufacturing of lipid-polymer nanoparticles through feedback control of parallelized swirling microvortices
    by Michael J. Toth on July 19, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2805-2813DOI: 10.1039/C7LC00668C, PaperMichael J. Toth, Taeyoung Kim, YongTae KimA variety of therapeutic and/or diagnostic nanoparticles (NPs), or nanomedicines, have been formulated for improved drug delivery and imaging applications.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D material cytometry (3DMaC): a very high-replicate, high-throughput analytical method using microfabricated, shape-specific, cell-material niches
    by Kirsten Parratt on July 19, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2861-2872DOI: 10.1039/C7LC00451F, PaperKirsten Parratt, Jenny Jeong, Peng Qiu, Krishnendu RoyStudying cell behavior within 3D material niches is key to understanding cell biology in health and diseases, and developing biomaterials for regenerative medicine applications.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Perspective on droplet-based single-cell sequencing
    by David A. Weitz on July 18, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2539-2539DOI: 10.1039/C7LC90069D, EditorialDavid A. WeitzThought leader David Weitz introduces the Lab on a Chip droplet-based single-cell sequencing thematic collection.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • InDrops and Drop-seq technologies for single-cell sequencing
    by Allon M. Klein on July 18, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2540-2541DOI: 10.1039/C7LC90070H, EditorialAllon M. Klein, Evan MacoskoDroplet-based single-cell sequencing pioneers Allon Klein and Evan Macosko summarise the growth of the technology and look ahead to future developments.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Micro-engineered perfusable 3D vasculatures for cardiovascular diseases
    by Nishanth Venugopal Menon on July 17, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00607A, PaperNishanth Venugopal Menon, Hui Min Tay, Soon Nan Wee, King Ho Holden Li, Han Wei HouA novel extracellular matrix patterning technique for engineering 3D biomimetic on-chip vasculatures for cardiovascular studies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Novel nanosensing technologies for exosome detection and profiling
    by Hyungsoon Im on July 17, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00247E, Critical ReviewHyungsoon Im, Kyungheon Lee, Ralph Weissleder, Hakho Lee, Cesar M. CastroThis article reviews recent advances of new assay platforms that are developed to facilitate molecular analyses of exosomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data
    by Pedro F. Costa on July 17, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2785-2792DOI: 10.1039/C7LC00202E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Pedro F. Costa, Hugo J. Albers, John E. A. Linssen, Heleen H. T. Middelkamp, Linda van der Hout, Robert Passier, Albert van den Berg, Jos Malda, Andries D. van der MeerStudying blood clotting in stereolithography 3D-printed microfluidic chips with endothelialised vascular structures.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • AC electric field controlled non-Newtonian filament thinning and droplet formation on the microscale
    by Y. Huang on July 16, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00420F, PaperY. Huang, Y. L. Wang, T. N. WongWe investigate the AC electric field controlled filament thinning and droplet formation dynamics of one non-Newtonian fluid. Furthermore, for the first time, we quantitatively measure the flow field of the non-Newtonian droplet formation under the influence of AC electric field, via a high-speed micro particle imaging velocimetry ([small mu ]PIV) system. We discover the viscoelasticity contributes to the discrepancies majorly.To cite this article before page numbers are assigned, use the DOI form of […]

  • A new droplet-forming fluidic junction for the generation of highly compartmentalised capsules
    by J. Li on July 13, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2873-2881DOI: 10.1039/C7LC00618G, PaperJ. Li, D. A. BarrowIn this work, we exhibit an oscillatory fluidic junction for the fabrication of definable compartmentalised micro-constructs.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic and nanofluidic phase behaviour characterization for industrial CO2, oil and gas
    by Bo Bao on July 13, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2740-2759DOI: 10.1039/C7LC00301C, Critical ReviewBo Bao, Jason Riordon, Farshid Mostowfi, David SintonWe critically review both microfluidic and emerging nanofluidic phase behaviour characterization methods for industrial CO2, oil and gas applications.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D-printed smartphone-based point of care tool for fluorescence- and magnetophoresis-based cytometry
    by Stephanie Knowlton on July 10, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2839-2851DOI: 10.1039/C7LC00706J, PaperStephanie Knowlton, Ashwini Joshi, Philip Syrrist, Ahmet F. Coskun, Savas TasogluWe propose a point-of-care-compatible smartphone-based platform for density-based cell sorting via magnetophoresis coupled with fluorescence imaging for versatile medical diagnostics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Integration and application of optical chemical sensors in microbioreactors
    by Pia Gruber on July 10, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2693-2712DOI: 10.1039/C7LC00538E, Tutorial Review Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pia Gruber, Marco P. C. Marques, Nicolas Szita, Torsten MayrThis tutorial review explains the integration of optical chemical sensor formats for the purpose of monitoring oxygen, pH, carbon dioxide, glucose and temperature in microbioreactors.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Holographic microscope slide in a spatio-temporal imaging modality for reliable 3D cell counting
    by Biagio Mandracchia on July 10, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2831-2838DOI: 10.1039/C7LC00414A, PaperBiagio Mandracchia, Vittorio Bianco, Zhe Wang, Martina Mugnano, Alessia Bramanti, Melania Paturzo, Pietro FerraroA Lab-on-a-Chip device for space-time digital holography is presented. Here, computational methods, holography, and microfluidics are intertwined to provide a reliable system for high-throughput counting of RBCs.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A novel 3-D bio-microfluidic system mimicking in vivo heterogeneous tumour microstructures reveals complex tumour-stroma interactions
    by Qihui Fan on July 9, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2852-2860DOI: 10.1039/C7LC00191F, PaperQihui Fan, Ruchuan Liu, Yang Jiao, Chunxiu Tian, James D. Farrell, Wenwen Diao, Xiaochen Wang, Fengrong Zhang, Wei Yuan, Haibo Han, Jinfeng Chen, Yue Yang, Xixiang Zhang, Fangfu Ye, Ming Li, Zhongcan Ouyang, Liyu LiuA 3-D microfluidic system consisting of microchamber arrays embedded in a collagen hydrogel with tunable biochemical gradients was constructed for investigating interactions between invasive breast cancer cells and stromal cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • An integrated microwell array platform for cell lasing analysis
    by Qiushu Chen on July 9, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2814-2820DOI: 10.1039/C7LC00539C, PaperQiushu Chen, Yu-Cheng Chen, Zhizheng Zhang, Biming Wu, Rhima Coleman, Xudong FanAutomated, high-throughput, and long-term cell laser detection was demonstrated by the integration of microwell arrays and Fabry-Perot cavities.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Spectral reading of optical resonance-encoded cells in microfluidics
    by Matjaz Humar on July 6, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2777-2784DOI: 10.1039/C7LC00220C, PaperMatjaz Humar, Avinash Upadhya, Seok Hyun YunWe demonstrate the feasibility of large-scale cell barcoding and identification using intracellular micro-resonators with different diameters.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Liter-scale production of uniform gas bubbles via parallelization of flow-focusing generators
    by Heon-Ho Jeong on July 5, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2667-2673DOI: 10.1039/C7LC00295E, PaperHeon-Ho Jeong, Sagar Yadavali, David Issadore, Daeyeon LeeA parallelized microfluidic device is used to generate highly monodisperse gas bubbles at a production rate of [similar]1 L h-1.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Rapid real-time recirculating PCR using localized surface plasmon resonance (LSPR) and piezo-electric pumping
    by J. M. Haber on July 5, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2821-2830DOI: 10.1039/C7LC00211D, PaperJ. M. Haber, P. R. C. Gascoyne, K. SokolovThe paper describes a novel on-chip microfluidic system for rapid highly sensitive and label-free multiplex detection of DNA molecules with specific focus on pathogen detection.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Point-of-care testing: applications of 3D printing
    by Ho Nam Chan on July 4, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2713-2739DOI: 10.1039/C7LC00397H, Critical ReviewHo Nam Chan, Ming Jun Andrew Tan, Hongkai WuWe review recent advancements adopting 3D printing in the POCT device development pipeline, highlighting its utility in all analytical stages.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Modeling electrical double-layer effects for microfluidic impedance spectroscopy from 100 kHz to 110 GHz
    by Charles A. E. Little on July 3, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2674-2681DOI: 10.1039/C7LC00347A, PaperCharles A. E. Little, Nathan D. Orloff, Isaac E. Hanemann, Christian J. Long, Victor M. Bright, James C. BoothOn-chip microwave calibrations are used to characterize the electrical-double layer response for saline solutions in microfluidic channels over an extremely broad frequency range.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Integrated sudomotor axon reflex sweat stimulation for continuous sweat analyte analysis with individuals at rest
    by Zachary Sonner on July 3, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2550-2560DOI: 10.1039/C7LC00364A, PaperZachary Sonner, Eliza Wilder, Trudy Gaillard, Gerald Kasting, Jason HeikenfeldEccrine sweat has rapidly emerged as a non-invasive, ergonomic, and rich source of chemical analytes with numerous technological demonstrations now showing the ability for continuous electrochemical sensing.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Design and modeling of electrode networks for code-division multiplexed resistive pulse sensing in microfluidic devices
    by Ruxiu Liu on June 29, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2650-2666DOI: 10.1039/C7LC00545H, PaperRuxiu Liu, Waqas Waheed, Ningquan Wang, Ozgun Civelekoglu, Mert Boya, Chia-Heng Chu, A. Fatih SariogluThe analysis of Microfluidic CODES, a code-multiplexed resistive-pulse sensor network for electrical acquisition of spatiotemporal particle manipulation on microfluidic devices.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Magnetically manipulated droplet splitting on a 3D-printed device to carry out a complexometric assay
    by T. J. Hutama on June 28, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2640-2649DOI: 10.1039/C7LC00629B, PaperT. J. Hutama, R. D. OleschukMagnetic actuation is used to dispense, translate, merge and mix droplets on a 3D-printed platform.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Characterisation of anticancer peptides at the single-cell level
    by L. Armbrecht on June 28, 2017 at 11:00 pm

    Lab Chip, 2017, Advance ArticleDOI: 10.1039/C7LC00505A, PaperL. Armbrecht, G. Gabernet, F. Kurth, J. A. Hiss, G. Schneider, P. S. DittrichCell response heterogeneity impedes success in chemotherapy outcome as well as hampers the development of efficacious anticancer therapeutics. We present a microfluidic screening platform capable of high-throughput monitoring of heterogeneous cell responses to anticancer peptides thereby enabling efficient screening for potential future drug candidates.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of […]

  • An automated optofluidic biosensor platform combining interferometric sensors and injection moulded microfluidics
    by C. Szydzik on June 27, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2793-2804DOI: 10.1039/C7LC00524E, PaperC. Szydzik, A. F. Gavela, S. Herranz, J. Roccisano, M. Knoerzer, P. Thurgood, K. Khoshmanesh, A. Mitchell, L. M. LechugaThis work presents an on-chip valve-based microfluidic automation module, capable of performing the complex fluid handling required for photonic biosensors.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Gel-seq: whole-genome and transcriptome sequencing by simultaneous low-input DNA and RNA library preparation using semi-permeable hydrogel barriers
    by Gordon D. Hoople on June 21, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2619-2630DOI: 10.1039/C7LC00430C, PaperGordon D. Hoople, Andrew Richards, Yan Wu, Kota Kaneko, Xiaolin Luo, Gen-Sheng Feng, Kun Zhang, Albert P. PisanoGel-seq enables researchers to simultaneously prepare libraries for both DNA and RNA from 100 cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multifunctional optofluidic lab-on-chip platform for Raman and fluorescence spectroscopic microfluidic analysis
    by G. Persichetti on June 20, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2631-2639DOI: 10.1039/C7LC00460E, PaperG. Persichetti, I. A. Grimaldi, G. Testa, R. BerniniA multifunctional platform for liquid spectroscopy is presented. Its performance is largely related to an optofluidic micro-jet waveguide approach.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Application of a strain rate gradient microfluidic device to von Willebrand's disease screening
    by Rose J. Brazilek on June 20, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2595-2608DOI: 10.1039/C7LC00498B, PaperRose J. Brazilek, Francisco J. Tovar-Lopez, Angus K. T. Wong, Huyen Tran, Amanda S. Davis, James D. McFadyen, Zane Kaplan, Sanjeev Chunilal, Shaun P. Jackson, Harshal Nandurkar, Arnan Mitchell, Warwick S. NesbittWe present the development of a strain rate gradient microfluidic device and apply it to the screening of von Willebrand's disease.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D printed conformal microfluidics for isolation and profiling of biomarkers from whole organs
    by Manjot Singh on June 19, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2561-2571DOI: 10.1039/C7LC00468K, PaperManjot Singh, Yuxin Tong, Kelly Webster, Ellen Cesewski, Alexander P. Haring, Sahil Laheri, Bill Carswell, Timothy J. O'Brien, Charles H. Aardema, Ryan S. Senger, John L. Robertson, Blake N. Johnson3D printed conformal microfluidics provide a novel approach for isolation and profiling of biomarkers from whole organs.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Thermoplastic elastomer with advanced hydrophilization and bonding performances for rapid (30 s) and easy molding of microfluidic devices
    by Julie Lachaux on June 15, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2581-2594DOI: 10.1039/C7LC00488E, PaperJulie Lachaux, Clara Alcaine, Blanca Gomez-Escoda, Cecile M. Perrault, David Olea Duplan, Pei-Yun Jenny Wu, Inaki Ochoa, Luis Fernandez, Olaf Mercier, Damien Coudreuse, Emmanuel RoySOFT THERMOPLASTIC material (USP Class VI).The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Soft, skin-mounted microfluidic systems for measuring secretory fluidic pressures generated at the surface of the skin by eccrine sweat glands
    by Jungil Choi on June 15, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2572-2580DOI: 10.1039/C7LC00525C, PaperJungil Choi, Yeguang Xue, Wei Xia, Tyler R. Ray, Jonathan T. Reeder, Amay J. Bandodkar, Daeshik Kang, Shuai Xu, Yonggang Huang, John A. RogersWe introduce a skin-mounted microfluidic device for measuring the secretory pressure of sweat glands at the surface of the skin.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multicomponent diffusion coefficients from microfluidics using Raman microspectroscopy
    by Christine Peters on June 13, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2768-2776DOI: 10.1039/C7LC00433H, PaperChristine Peters, Ludger Wolff, Sandra Haase, Julia Thien, Thorsten Brands, Hans-Jurgen Ko[German sz ligature}, Andre BardowMicrofluidic measurement of multicomponent diffusion coefficients using minimal number of experiments with high accuracy in short time.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • On-chip cell sorting by high-speed local-flow control using dual membrane pumps
    by Shinya Sakuma on June 13, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2760-2767DOI: 10.1039/C7LC00536A, PaperShinya Sakuma, Yusuke Kasai, Takeshi Hayakawa, Fumihito AraiWe achieved high-throughput on-chip sorting of large cells by using on-chip dual membrane pumps integrated with a high-rigidity microfluidic chip. In the case of Euglena gracilis sorting, the throughput was 23 kHz with 92.8% success rate, 95.8% purity, and 90.8% cell viability.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans
    by Yongmin Cho on June 12, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2609-2618DOI: 10.1039/C7LC00465F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yongmin Cho, Daniel A. Porto, Hyundoo Hwang, Laura J. Grundy, William R. Schafer, Hang LuA new automated microfluidic platform can deliver a wide range of mechanical stimuli for functional neural imaging in C. elegans.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Size-tunable microvortex capture of rare cells
    by Reem Khojah on June 4, 2017 at 11:00 pm

    Lab Chip, 2017, 17,2542-2549DOI: 10.1039/C7LC00355B, PaperReem Khojah, Ryan Stoutamore, Dino Di CarloA wide distribution of cell sizes can be selectively captured by tuning the flow rate in a micro-vortex flow.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Analytical Chemistry: Latest Articles (ACS Publications) latest articles published in Analytical Chemistry

    • Development of a modified electrode by using a nanocomposite containing acid-activated multi-walled carbon nanotube and fumed silica for the voltammetric determination of clopyralid
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Ali Özcan, Mustafa GürbüzThis is the first study in the literature, which presents the voltammetric determination of herbicide clopyralid (CLD). A novel modified glassy carbon electrode was developed by using the nanocomposite containing acid-activated multi-walled carbon nanotube (A-MWCNT) and fumed silica (FS). The effective surface area of the electrode (8 times) and the reduction peak current values of CLP (369 times) increased in the presence of A-MWCNT-FS […]

    • Nanotube-on-graphene heterostructures for three-dimensional nano/bio-interface
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Sun Sang Kwon, Jae Hyeok Shin, Jonghyun Choi, SungWoo Nam, Won Il ParkWe report the synthesis, fabrication, and characterization of a nanotube-on-graphene (NT-on-Gr) field-effect sensor array for electrical detection of the biological activity of living cells. In order to form vertical nanotubes on a graphene surface, Ge/Si core-shell nanowires were vertically grown on graphene, followed by cap opening and Ge core-etching processes. Source-drain current versus water-gate potential […]

    • Highly sensitive and selective detection of ethanol vapor using flame-spray-made CeOx-doped SnO2 nanoparticulate thick films
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): N. Kotchasak, A. Wisitsoraat, A. Tuantranont, S. Phanichphant, V. Yordsri, C. LiewhiranIn the present work, flame-spray-made CeOx-doped SnO2 nanoparticles with 0.1–1wt% Ce contents were systematically studied for ethanol detection. Structural characterizations by electron microscopy, Nitrogen adsorption and X-ray analysis indicated that SnO2 nanoparticles were highly crystalline with tetragonal structure and CeOx crystallites with mixed Ce3+ and Ce4+ oxidation states […]

    • Tenfold enhancement of fluorescence quantum yield of water soluble silver nanoclusters for nano-molar level glucose sensing and precise determination of blood glucose level
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Shagufta Naaz, Soumabrota Poddar, Shyama Prasad Bayen, Maloy Kr. Mondal, Debiprasad Roy, Sudip Kr. Mondal, Pranesh Chowdhury, Samar Kr. SahaSpecially designed water soluble fluorescent silver nanoclusters anchored with 3-aminophenyl boronic acid (AgNCs-a-APBA) have been synthesized sonochemically in environmentally benign water medium. The new material (AgNCs-a-APBA) shows tenfold enhancement of fluorescence intensity compared to AgNCs. Fluorescence quenching experiments […]

    • Thiol-triggered disaggregation-induced emission controlled by competitive coordination for acetylcholinesterase monitoring and inhibitor screening
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Jing Xu, Fengqi Zhou, Luxi Chen, Guilin Chen, Saifei Pan, Zhaosheng Qian, Hui FengAcetylcholinesterase (AChE) is an important biomarker of many neurotransmitter-associated diseases and can be used to screen potential drugs and diagnose poisoning by chemical warfare agents and pesticides, and thus the accurate detection of AChE is of great practical significance. In this work, thiol-triggered disaggregation-induced emission through competitive interaction among […]

    • Aptamer-based electrochemical biosensor for highly sensitive and selective malaria detection with adjustable dynamic response range and reusability
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Gabriela Figueroa-Miranda, Lingyan Feng, Simon Chi-Chin Shiu, Roderick Marshall Dirkzwager, Yee-Wai Cheung, Julian Alexander Tanner, Michael Josef Schöning, Andreas Offenhäusser, Dirk MayerMalaria infection remains a significant risk for much of the population of tropical and subtropical areas, particularly in developing countries. Therefore, it is of high importance to develop sensitive, accurate and inexpensive malaria diagnosis tests. Here, we present a […]

    • Fully contactless system for crayfish heartbeat monitoring: Undisturbed crayfish as bio-indicator
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Petr Císař, Mohammadmehdi Saberioon, Pavel Kozák, Aliaksandr PautsinaThe crayfish is widely accepted as very sensitive and fast bio-indicator of changes in water quality. Studies based on heart beat analysis demonstrated the potential of using crayfish as a detector of pollutants consequently several computer-aided systems were developed to use this mechanism. The main complication with applying such a system is the necessity of using metal wires or optical […]

    • A highly selective, sensitive and reusable BODIPY based ‘OFF/ON' fluorescence chemosensor for the detection of Hg2+ Ions
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Apurba Maity, Amit Sil, Subhra Nad, Sanjib K. PatraA BODIPY (borondipyrromethane) based fluorescence probe anchored with N,N-bis(2-(pyridin-2-ylmethoxy)ethyl)aniline receptor (BDPS) has been designed, synthesized and successfully characterized. It can selectively sense Hg2+ ion by giving significant emission enhancement at 514nm over other biologically and environmentally relevant metal ions in CH3CN/H2O (1:1) medium. The turn-on behaviour of the sensor is due to the metal […]

    • In situ enhanced electrochemiluminescence based on co-reactant self-generated for sensitive detection of microRNA
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Liping Lu, Chang Liu, Tianfang Kang, Xiayan Wang, Guangsheng Guo, Wujian MiaoAn ultrasensitive and selective miRNA biosensor based on the luminol-H2O2 electrochemiluminescence (ECL) system using hemin as a catalyzer for in situ ECL signal enhancement was reported. DNA probe was tethered onto the electrodeposited Au nanoparticles on a glassy carbon electrode, and the remaining active sites were then blocked with glucose oxidase (GOD). Subsequently, followed by miRNA […]

    • A tissue-permeable fluorescent probe for Al (III), Cu (II) imaging in vivo
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Xin Zhang, Ping Sun, Fei Li, Hong Li, Hongping Zhou, Hui Wang, Baowei Zhang, Zhongwen Pan, Yupeng Tian, Xuanjun ZhangWith the increasing of human activities, the issue of environmental pollution is currently more and more serious, such as Al3+ (Cu2+) pollutants which deeply influenced the growth of animal and plant life. Meantime, detecting them in living tissues are largely restricted by biocompatibility of probes. Herein, we use triphenylamine fluorophore and […]

    • A mitochondria-targeted colorimetric and ratiometric fluorescent probe for hydrogen peroxide with a large emission shift and bio-imaging in living cells
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Youming Shen, Xiangyang Zhang, Youyu Zhang, Yanyang Wu, Chunxiang Zhang, Yuandao Chen, Junling Jin, Haitao LiA novel mitochondria-targeted fluorescent probe compound 1 for H2O2 has constructed based on a coumarin as the fluorophore and a boronate moiety as the reaction site, which showed colorimetric and ratiometric fluorescence dual response to H2O2. This probe displayed a large blue-shifted in emission wavelength (105nm) with two well-resolved emission bands toward […]

    • Ultrasound assisted electrochemical distinction of normal and cancerous cells
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Mohammad Ali Khayamian, Saeid Ansaryan, Saeed Rafizadeh Tafti, Mohammad Saeed Nikshoar, Morteza Hassanpour Amiri, Majid Baniassadi, Mohammad AbdolahadCyclic voltammetry (CV) is applied to monitor the sonoporative behavior of normal and cancer breast cells. Novel electrochemically produced microbubbles in the solution induce acoustic cavitation in the cells by ultrasonic stimulation (US). This makes sonoporation in the cells which exchanges ionic species between inner and […]

    • Selective and sensitive detection of Zn(II) ion using a simple peptide-based sensor
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Jiajia Wan, Wenxiu Duan, Kai Chen, Yanduo Tao, Jun Dang, Kehao Zeng, Yushu Ge, Jiang Wu, Dan LiuThe development of biocompatible chemosensors is becoming increasingly important for chemical analyses in environmental sampling, the food industry, and clinical medicine. Many current chemosensors have limited utility as they represent potential secondary pollutants. To circumvent this problem, researchers are evaluating peptide-based fluorescent chemosensors because of […]

    • A novel electrochemical chiral sensor for tyrosine isomers based on a coordination-driven self-assembly
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yongxin Tao, Fuqiang Chu, Xiaogang Gu, Yong Kong, Yongqi Lv, Linhong DengAlfa-cyclodextrin (α-CD) based chiral sensing device is proposed for electrochemical recognition of tyrosine (Tyr) isomers. α-CD was first modified with Cu2+, and then the obtained Cu2+-modified α-CD (Cu2-α-CD) was integrated to chitosan (CS) to form a coordination-driven self-assembly. The amino group and phenolic hydroxyl group of Tyr could form three intermolecular H-bonds with […]

    • High-performance fibre-optic humidity sensor based on a side-polished fibre wavelength selectively coupled with graphene oxide film
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yaoming Huang, Wenguo Zhu, Zhibin Li, Guanglei Chen, Liheng Chen, Junjie Zhou, Hai Lin, Junwen Guan, Wenxiao Fang, Xin Liu, Huazhuo Dong, Jieyuan Tang, Heyuan Guan, Huihui Lu, Yi Xiao, Jun Zhang, Hongcheng Wang, Zhe Chen, Jianhui YuA high-performance humidity sensor based on a side-polished single-mode fibre (SPF) coated with graphene oxide film was fabricated with a wheel side-polishing technique and spontaneous evaporation. The wavelength-selective […]

    • “Turn off-on” phosphorescent sensor for biothiols based on a Ru-Cu ensemble
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Pingyu Zhang, Yi Wang, Wenxiu Huang, Zhiqian Zhao, Haihang Li, Haitao Wang, Chuanxin He, Jianhong Liu, Qianling ZhangGlutathione (GSH), cysteine (Cys), and homocysteine (Hcy) are three major biothiols, which play key roles in various biological systems. Accordingly, the development of phosphorescent probe of biothiols has attracted great attention in clinical applications. Here we report a ruthenium polypyridyl complex (1), which shows large phosphorescence quenching […]

    • Transfer of preheat-treated SnO2 via a sacrificial bridge-type ZnO layer for ethanol gas sensor
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Da Hoon Lee, Sun Kil Kang, Yusin Pak, Namsoo Lim, Ryeri Lee, Yogeenth Kumaresan, Sungeun Lee, Chaedeok Lee, Moon-Ho Ham, Gun Young JungThe progress in developing the microelectromechanical system (MEMS) heater-based SnO2 gas sensors was hindered by the subsequent heat treatment of the tin oxide (SnO2), nevertheless it is required to obtain excellent sensor characteristics. During the sintering process, the MEMS heater and the contact electrodes can be degraded at such […]

    • Electrodeposited nanoporous ruthenium oxide for simultaneous quantification of ascorbic acid and uric acid using chronoamperometry at two different potentials
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yejin Yang, Ara Jo, Youngmi Lee, Chongmok LeeNanoporous ruthenium dioxide (RuO2) was simply prepared by electrodeposition with potential cycling in RuCl3 solution in the presence of reverse micelles of Triton X-100. The electrodeposited RuO2 on Au substrate electrode showed high electroactivity for the oxidations of L-ascorbic acid (AA) and uric acid (UA), while AA oxidation started from a less positive potential compared to UA oxidation. Simultaneous quantitative analysis of AA […]

    • Reversible and fast responding ppb level Cl2 sensor based on noncovalent modified carbon nanotubes with Hexadecafluorinated copper phthalocyanine
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Anshul Kumar Sharma, Aman Mahajan, Rajan Saini, R.K. Bedi, Subodh Kumar, A.K. Debnath, D.K. AswalHybrids of hexadecafluorinated copper phthalocyanine (F16CuPc) with carboxylic functionalized single-walled carbon nanotubes (SWCNTs-COOH) and multi-walled carbon nanotubes (MWCNTs-COOH) have been synthesized using a solution assembly method. The resulting hybrid materials have been characterized by Transmission electron microscopy, Raman, UV–vis, X-Ray photoelectron, […]

    • Freshness assessment of intact fish via 2D 1H J-resolved NMR spectroscopy combined with pattern recognition methods
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Chunhua Tan, Yuqing Huang, Jianghua Feng, Zhishui Li, Shuhui CaiFreshness of intact zebrafish was evaluated by 2D 1H J-resolved NMR spectroscopy conjugated with pattern recognition methods Without complicated sample pretreatment and specialized hardware settings, the biochemical processes of intact zebrafish from fresh to decay state and the corresponding metabolite profiles were acquired. A total of 21 metabolites were identified and their concentration variations during the […]

    • Ultrasensitive SERS detection of propranolol based on sandwich nanostructure of molecular imprinting polymers
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yajiao Liu, Jingjing Bao, Lei Zhang, Chen Chao, Jianjun Guo, Yuchuan Cheng, Yuejin Zhu, Gaojie XuPropranolol (PRO) is a β-blocker used in the treatment of heart disease. Recently, it has become a kind of organic pollutions due to its wide-spread use. However, the reliable and rapid analytical method for detection and monitoring PRO is still a challenge. We design a novel sandwich nanostructure for the specific and sensitive determination of trace propranolol in […]

    • A Rayleigh surface acoustic wave (R-SAW) resonator biosensor based on positive and negative reflectors with sub-nanomolar limit of detection
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Matteo Agostini, Gina Greco, Marco CecchiniA label-free sub-nanomolar Rayleigh surface acoustic wave (R-SAW)-based resonator biosensor is demonstrated for biomolecular detection in liquid after drying. The biosensor comprises two interdigital transducers for R-SAW generation and two positive and negative reflectors to confine the acoustic energy in the sensitive area. We benchmark this biosensor against biotin-streptavidin binding, which is a standard, well-known model for a variety of […]

    • Rapid prototyping of whole-thermoplastic microfluidics with built-in microvalves using laser ablation and thermal fusion bonding
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Seyed Ali Mousavi Shaegh, Adel Pourmand, Mahboubeh Nabavinia, Huseyin Avci, Ali Tamayol, Pooria Mostafalu, Habib Badri Ghavifekr, Esmaeil Najafi Aghdam, Mehmet Remzi Dokmeci, Ali Khademhosseini, Yu Shrike ZhangRecently, there has been an increasing effort in developing new fabrication methods for rapid prototyping of microfluidic chips using thermoplastic materials. This is mainly due to the excellent properties of thermoplastics including inherent robustness to […]

    • Controlled synthesis and humidity sensing properties of CdS/polyaniline composite based on CdAl layered double hydroxide
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Qingqing Chen, Meixiang Nie, Ying GuoCdS/polyaniline (CdS/PANI) composite with sandwich structure has been prepared by vulcanization process of polyaniline and sodium dodecyl sulfonate (SDS) co-intercalated CdAl layered double hydroxide (CdAl-LDH/PANI), which has been obtained by traditional method of hydrothermal synthesis. CdAl-LDH/PANI precursor and CdS/PANI composite have been characterized by X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), Scanning electron […]

    • Rapid detection of trace ozone in TiO2–In2O3 materials by using the differential method
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Chun-Han Wu, Tung-Lin Chou, Ren-Jang WuTiO2–In2O3 composites were fabricated for detecting trace amounts of gaseous ozone and were characterized using transmission electron microscopy, X-ray diffraction, and ultraviolet–visible spectrophotometry. The fabricated TiO2–In2O3 composites exhibited a high ozone gas sensor response of 56.5–2.0ppm at room temperature (25±2°C) under irradiation at 405nm using a light-emitting diode. The differential […]

    • Reliable electrochemical sensing arsenic(III) in nearly groundwater pH based on efficient adsorption and excellent electrocatalytic ability of AuNPs/CeO2-ZrO2 nanocomposite
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Meng Yang, Pei-Hua Li, Wei-Hong Xu, Yan Wei, Li-Na Li, Yu-Ying Huang, Yu-Feng Sun, Xing Chen, Jin-Huai Liu, Xing-Jiu HuangEven though electrochemical analytical tools have been widely investigated for toxic As(III) detection and the achievements have also been so fruitful. However, electroanalysis method with efficient and high anti-interference toward As(III) in the original pH of natural water is still scarce and urgent. To this end, in this work, a sensing […]

    • Label-free electrochemical immunosensor based on flower-like Ag/MoS2/rGO nanocomposites for ultrasensitive detection of carcinoembryonic antigen
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yaoguang Wang, Yulan Wang, Dan Wu, Hongmin Ma, Yong Zhang, Dawei Fan, Xuehui Pang, Bin Du, Qin WeiIn this work, a label-free electrochemical immunosensor was developed for the quantitative detection of carcinoembryonic antigen (CEA). Flower-like Ag/MoS2/rGO nanocomposites were employed as the signal amplification platform of the designed immunosensor for the first time. Due to the synergistic effect between molybdenum disulfide (MoS2), reduced graphene oxide (rGO) and […]

    • Imaging and distribution of Cd(II) ions in electrotrophs and its response to current and electron transfer inhibitor in microbial electrolysis cells
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Liping Huang, Hua Xue, Qian Zhou, Peng Zhou, Xie QuanBiocathode microbial electrolysis cells (MECs) with electrotrophs on the cathodes are proved to be attractive for Cd(II) removal with simultaneous hydrogen production. However, the underlying roles of current and electron transfer inhibitor of 2,4-dinitrophenol (2,4-DNP) in the distribution of dissolved Cd(II) ions in the electrotrophs are largely unknown. Based on four indigenous electrotrophs (Ochrobactrum sp X1, […]

    • Polydopamine-assisted decoration of TiO2 nanotube arrays with enzyme to construct a novel photoelectrochemical sensing platform
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Jianan Li, Xinyong Li, Qidong Zhao, Zao Jiang, Moses Tadé, Shaobin Wang, Shaomin LiuA novel photoelectrochemical (PEC) biosensing platform coupling with enzyme-induced biocatalytic precipitation (BCP) for H2O2 was successfully constructed. TiO2 nanotube arrays (TNs) were coated with polydopamine (PDA) and horseradish peroxidase (HRP) as the PEC electrode through a facile method. PDA was incorporated into the sensor system not only as a sensitizing agent to alter the […]

    • Quantum dots based imprinting fluorescent nanosensor for the selective and sensitive detection of phycocyanin: A general imprinting strategy toward proteins
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Xiaoyan Wang, Jialuo Yu, Jinhua Li, Qi Kang, Dazhong Shen, Lingxin ChenMolecular imprinting as a versatile technology has gained popularity in various fields for diverse species; however, protein imprinting still remains challenging due to some inherent problems but is potentially rewarding work. Herein, we reported a facile strategy to imprint phycocyanin (PC), as a template, using quantum dots (QDs) co-capped by thioglycollic acid and glutathione directly as functional […]

    • Highly sensitive electrochemical assay for Bisphenol A detection based on poly (CTAB)/MWCNTs modified pencil graphite electrodes
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Gulcin Bolat, Yesim Tugce Yaman, Serdar AbaciIn this work, we offered a cheap, effective and a rapid electrochemical detection of Bisphenol A (BPA) in a simple methodology. Cetyltrimethylammonium bromide (CTAB) and multi- walled carbon nanotubes (MWCNTs) were combined through electropolymerization onto pencil graphite electrode (PGE) surface by cyclic voltammetry to produce poly (CTAB)-MWCNTs composite. Electrochemical signal of BPA at poly (CTAB)-MWCNTs modified PGE was […]

    • A novel turn-off fluorescent probe based on TICT for the detection of NO2 and nitramines with high sensitivity and selectivity
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Jian-Bo Chen, Baosheng Li, Ying Xiong, Jie SunTwo new fluorescent probes based on a coumarin core have been developed for the detection of nitramines (RDX and HMX) via responding to their photo-degradated nitrogen dioxide (NO2). Although both probes contain the same fluorophore and recognition site, they display different fluorescent responses to NO2 and nitramines. 8-Oxime-7-dimethylamino-coumarin (8-ODC) emits traditional turn-on fluorescence toward NO2, which is based on the […]

    • Hemoglobin immobilized in g-C3N4 nanoparticle decorated 3D graphene-LDH network: Direct electrochemistry and electrocatalysis to trichloroacetic acid
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Tianrong Zhan, Zhengwei Tan, Xinjun Wang, Wanguo HouA 3D hybrid of graphitic C3N4 nanoparticle decorated in the assembly of graphene and Co2Al layered double hydroxide nanosheets (GR-LDH-C3N4) was prepared by simple hydrothermal treatment and subsequent calcination-recovery process. X-ray diffraction, scanning electron microscopy, transmission electron microscopy and X-ray photoelectron spectroscopy clearly demonstrated that the g-C3N4 nanoparticle was successful incorporated […]

    • Size-controlled synthesis of fluorescent tungsten oxide quantum dots via one-pot ethanol-thermal strategy for ferric ions detection and bioimaging
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yan Zhan, Yingliang Liu, Qingqing Liu, Zhiming Liu, Haiyao Yang, Bingfu Lei, Jianle Zhuang, Chaofan HuAs one typical semiconductor material, tungsten oxide (WO3) has captivated intensive attention owing to its multifunctional properties. However, exploring a facile and one-pot strategy for controllable synthesis of fluorescent tungsten oxide quantum dots (WO3 QDs) is still very challenging. In this paper, WO3 QDs were prepared via a facile and one-pot ethanol-thermal […]

    • Oxygen vacancies and grain boundaries potential barriers modulation facilitated formaldehyde gas sensing performances for In2O3 hierarchical architectures
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Shuangming Wang, Jing Cao, Wen Cui, Longlong Fan, Xifei Li, Dejun LiThe distinctive In2O3 hierarchical architectures are successfully prepared via a facile solution route at room temperature combined with a subsequent thermal treatment. Microstructural characterizations by means of SEM, TEM and XRD indicate the as-prepared In2O3 hierarchical architectures are assembled by nanoparticles and show loose porous surfaces. The room temperature PL spectra and BET surface area […]

    • Label-free electrochemical aptasensing platform based on mesoporous silica thin film for the detection of prostate specific antigen
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Wicem Argoubi, Alfredo Sánchez, Concepción Parrado, Noureddine Raouafi, Reynaldo VillalongaWe report the development of a novel label-free electrochemical aptasensing platform to detect prostate specific antigen (PSA) based on mesoporous silica thin film-coated gold electrodes as a sensing interface. The aptasensing approach relies on hindering the diffusion of [Fe(CN)6]3/4− redox probe through the nanochannels of the mesoporous film gated by the recognition […]

    • Highly improved simultaneous herbicides determination in water samples by differential pulse voltammetry using boron-doped diamond electrode and solid phase extraction on cross-linked poly(vinylimidazole)
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Eduardo Henrique Duarte, Juliana Casarin, Elen Romão Sartori, César Ricardo Teixeira TarleyA highly sensitive method for the simultaneous determination of multiresidues of diuron (DI), 2,4- dichlorophenoxyacetic acid (2,4-D) and tebuthiuron (TB) using a cathodically pretreated boron-doped diamond electrode (BDDE) by differential pulse voltammetry (DPV) associated with solid phase extraction was developed. The method is based on preconcentration of 100.0mL of […]

    • Highly selective chromogenic probe for cesium ions prepared from an electrospun film of self-assembled benzenetricarboxyamide nanofibers
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Junho Ahn, Na Young Lim, Yeonweon Choi, Myong Yong Choi, Jong Hwa JungCesium is a common contaminant in industrial, medical, and nuclear wastes, and can cause several health problems. Therefore, the development of chemical probes and absorbents for cesium is important for the medical, biological, and industrial fields. Herein, we report the sensing ability of tri- or dihydroxylphenyl-appended benzenetricarboxyamides (BTAs 1 and 2, respectively) as chromogenic probes for cesium […]

    • A highly specific BODIPY-based fluorescent probe for the detection of nerve-agent simulants
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Zhengliang Lu, Wenlong Fan, Xiaomin Shi, Cory A. Black, Chunhua Fan, Fangfang WangNerve agents such as Sarin, Soman and Tabun are all very toxic organophosphorus (OP) compounds capable of being used as chemical weapons. Unfortunately, the ability to rapidly sense OPCs is still an ongoing challenging. In this report, we designed and synthesized a fast-response fluorescent probe (1) for the detection of OP nerve agent simulants with high selectivity and sensitivity. The probe […]

    • Disposable aptasensor combining functional magnetic nanoparticles with rolling circle amplification for the detection of prostate-specific antigen
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Cheng-Yu Lee, Hsiao-Ting Fan, You-Zung HsiehThis paper describes a disposable and accurate aptasensor—that functions with signal amplification—for prostate-specific antigen (PSA) analysis in neutral (pH 7.4) condition. Combining aptamer-immobilized magnetic nanoparticles with rolling circle amplification (RCA) has provided a PSA detector with adequate sensitivity. In the absence of PSA, a portion of the complementary DNA-primer (cDNA-primer) bound with the aptamer and […]

    • Nanoscale graphene oxide-induced metallic nanoparticle clustering for surface-enhanced Raman scattering-based IgG detection
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Ahmed Ali, Eun Young Hwang, Jaebum Choo, Dong Woo LimSurface-enhanced Raman scattering (SERS) has been of great interest to advance sensitive optical biosensors. Clustered metallic nanoparticles as SERS nanoprobes are important to detect specific biomolecules with ultra-sensitivity. We report herein that the cluster formation of gold nanoparticles (GNPs) was induced by nanoscale graphene oxides (NGOs) with 120nm to develop a new class of SERS nanotags for biosensing. The GNPs […]

    • Multi-component optical sensing of high temperature gas streams using functional oxide integrated silica based optical fiber sensors
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Miaolei Yan, Joseph Tylczak, Yang Yu, Grigorios Panagakos, Paul OhodnickiIn-situ monitoring of the multi-component gas streams in high temperature energy conversion devices offer the promises to higher efficiency via improved understanding of the chemical environments during device operation. While conventional resistive based metal oxide semiconductor gas sensors suffer from strong cross-sensitivity, optical sensing approaches offer intrinsic advantages to achieve gas […]

    • Mitochondria-targeted two-photon fluorescent probe for the detection of biothiols in living cells
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yi Li, Kang-Nan Wang, Bing Liu, Xin-Ran Lu, Meng-Feng Li, Liang-Nian Ji, Zong-Wan MaoMitochondrial thiols play a key role in maintaining the redox environment. In this work, three mitochondria-targeted two-photon probes (1–3) have been explored to detect biothiols in vitro and in vivo with a large turn-on fluorescence signal. These fluorescence probes display sensitive and selective response to thiols in the water environment, feature good linearity ranges with low […]

    • A three-dimensional and bevel-angled ultrahigh aspect ratio microneedle for minimally invasive and painless blood sampling
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Dae-Sik Lee, Cheng Guo Li, Chunhwa Ihm, Hyungil JungIn spite of the invasiveness and pain related with it, blood sampling is necessary in point-of-care systems to obtain biochemical information. In this context, a substitute micro-scale needle for minimally invasive and painless blood sampling has been developed. In conventional microneedle fabrication methods, it is difficult to combine the features of a sharp tip shape, appropriate length, and a hollow structure simultaneously. […]

    • Flexible poly (3, 3′′′- dialkylquaterthiophene) based interdigitated metal-semiconductor-metal ammonia gas sensor
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Chandan Kumar, Gopal Rawat, Hemant Kumar, Yogesh Kumar, Rajiv Prakash, Satyabrata JitIn this article, poly (3, 3′′′- dialkylquaterthiophene) (PQT-12) thin film based interdigitated metal-semiconductor-metal (MSM) is fabricated by a spin coating method on flexible polyamide substrate for ammonia (NH3) gas sensing applications possibly for the first time. The average roughness, root mean square roughness, peak-to-peak spacing, average grain size, and grain […]

    • Highly selective and sensitive detection of Hg2+ based on fluorescence enhancement of Mn-doped ZnSe QDs by Hg2+-Mn2+ replacement
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Zhi-Qiang Zhou, Ren Yan, Jie Zhao, Li-Yun Yang, Ji-Lei Chen, Yan-Jun Hu, Feng-Lei Jiang, Yi LiuThe pollution of Hg2+ is one of the most serious problems to human health due to their high toxicity, mobility, difficulty in degradation and ability of accumulation in ecological systems. Thus, it is of great importance to develop highly selective and sensitive probe for detecting Hg2+ in aquatic ecosystems. Here we propose a new turn-on strategy for specific recognition and detection […]

    • Mercaptobenzoheterocyclic compounds functionalized silver nanoparticle, an ultrasensitive colorimetric probe for Hg(II) detection in water with picomolar precision: A correlation between sensitivity and binding affinity
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Yudhajit Bhattacharjee, Dipanwita Chatterjee, Amarnath ChakrabortyToxic heavy metal ions, specially Hg(II) pose lethal threat to the environment and human beings. To this end, there is a strong need to establish a simple, inexpensive method for the detection of Hg(II) ions with high selectivity and sensitivity in aqueous medium. Herein, we report an ultra-sensitive colorimetric detection of Hg(II) ions following a simple protocol by synthesizing silver nanoparticles functionalized […]

    • A new fluorescent chemodosimeter for ultra-sensitive determination of toxic thiophenols in environmental water samples and cancer cells
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Feng Wu, Hongying Wang, Junchao Xu, Hou-Qun Yuan, Lintao Zeng, Guang-Ming BaoA novel fluorescent chemodosimeter for thiophenols has been readily developed from a red emitting Indole-BODIPY. The chemodosimeter displays a significant fluorescence turn-on response towards thiophenols based on nucleophilic substitution reaction. A linear relationship was obtained between the fluorescence intensity and the concentrations of thiophenols ranging from 0 to 1.8μM. The chemodosimeter can […]

    • f-MWCNTs-PIN/Ti2O3 nanocomposite: Preparation, characterization and nanomolar detection of α-Lipoic acid in vegetables
      on August 19, 2017 at 2:33 pm

      Publication date: February 2018Source:Sensors and Actuators B: Chemical, Volume 255, Part 1 Author(s): Ragu Sasikumar, Palraj Ranganathan, Shen-Ming Chen, Syang-Peng RweiA highly sensitive, and selective α-Lipoic acid (ALA) sensor based on a functionalized multi-walled carbon nanotubes-polyindole/Ti2O3 (f-MWCNTs-PIN/Ti2O3) nanocomposite modified glassy carbon electrode (GCE) was developed. The fabricated f-MWCNTs-PIN/Ti2O3/GCE displayed an enhanced voltammetric response for oxidation towards ALA relative to that of a f-MWCNTs/GCE, f-MWCNTs-PIN/GCE, Ti2O3/GCE, and a bare GCE. […]

    • InGaZnO transistor based on porous Ag nanowire-functionalized gate electrode for detection of bio-relevant molecules
      on August 19, 2017 at 2:33 pm

      Publication date: January 2018Source:Sensors and Actuators B: Chemical, Volume 254 Author(s): Tae-Hee Yoo, Hi Gyu Moon, Byung-Yong Wang, Byoung-In Sang, Basavaraj Angadi, Young-Jei Oh, Won Kook Choi, Chong-Yun Kang, Do Kyung HwangWe report on InGaZnO (IGZO) thin film transistors (TFTs)-based bio-chemical sensors which can detect the chemical/biological species. As novel sensing platform, the IGZO TFT with Ag nanowire (NW) mesh showed pronounced output voltage changes responding to all analytes of H2O2, b-d-glucose, d-glucono-1,5-Lactione, and lactic acid, which are […]

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