Application Engineer: Ashok Sinha, Dolomite Microfluidics, UK 

Introduction: 

This presentation addresses on the microfluidics market, identifies technological bottlenecks, and showcases a few successful and fast growing applications. Among these are cell encapsulation, droplet generation, high-throughput droplets & particles, double emulsions, nanoparticle synthesis, and droplets on demand.

Transcript: 

Group Introduction
Top Applications

• Cell Encapsulation
• Microparticle Production
• Nanoparticle synthesis

Application:

• Biology e.g. cell encapsulation in microdroplets and anyalysis of individual cells fom a population
• Drug discovery e.g. drug formulaion and controlled release via biodegradable particles
• Chemistry e.g. nanoparticle synthesis and petrochemical analysis
• Food and cosmetics e.g. bulk precision manufacturing of emulsions and foams
• Academia e.g. study of microfluidics and nanofluidic droplets or bubbles

Product Overview-Modules and Components

Application 1- Encapsulation of DNA/cells

• Protein Based Assay for Surface Immobilized Antibodies
• Compartmentalizing biochemical Reactions for Sorting by FACS
• Density Matching Assistance Suspension(PCR)
• Uses of Cell Encapsluation
  – Uses of polymer particles
  – Diagnostic tests and assays
  – Controlled drug release or targeted drug delivery
  – Mobile substrates with custom functionalization including magnetic particles
  – Imaging- micro-PIV (particle image velocimetry)

Application 2- Polymer Microparticle/Bead Formation

• Batch vs. Continuous Particle Production Methods
• Solvent extraction method of solid->liquid phase change
• Application 3- Nanoparticle synthesis

Other Applications: 

• Anti-solvent method of nucleation/precipitation
• Micromixer system

Summary

 

Source: Labtube