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Book Description: 

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.

The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focusing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.

Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.

         Part I Fundamentals of microfluidic technologies for biomedical applications

         1. Materials and methods for the microfabrication of microfluidic biomedical devices

             W.-I. Wu, P. Rezai, H.-H. Hsu, R. Selvaganapathy, McMaster University, Canada

         2. Surface coatings for microfluidic-based biomedical devices

            G. Abdallah and A. Ros, Arizona State University, USA

         3. Actuation mechanisms for microfluidic biomedical devices

            Rezk, J. Friend and L. Yeo, RMIT University, Australia

         4. Digital microfluidics technologies for biomedical devices

            M. Collier, J. Nichols and J. F. Holzman, The University of British Columbia, Canada

        Part II Applications of microfluidic devices for drug delivery and discovery

         5. Controlled drug delivery using microfluidic devices

             Gao, Harvard University, USA and X.J. Li, University of Texas at El Paso, USA

         6. Microneedles for drug delivery applications

            R. R. Singh, H. McMillan, K. Mooney, A. Z. Alkilani, R. F. Donnelly, Queens University Belfast, UK

         7. Microfluidic devices for drug discovery and analysis

            S. Kochhar, S. Y. Chan, P. S. Ong. and L. Kang, National University of Singapore, Singapore

        Part III Applications of microfluidic devices for cellular analysis and tissue engineering

         8. Microfluidic devices for cell manipulation

           O. Fatoyinbo, University of Surrey, UK

         9. Microfluidic devices for automated micro-robotic cell injection and trapping
X. Liu, McGill University, Canada and Y Sun, University of Toronto, Canada

        10. Microfluidic devices for developing tissue scaffolds

           T. Chau, J. E. Frith, R. J. Mills and J. Cooper-White, The University of Queensland, Australia

         11. Microfluidic devices for stem cell analysis

            D.-K. Kang J. Lu W. Zhang E. Chang M. A. Eckert M. M. Ali W. Zhao, University of California

        Part IV Applications of microfluidic devices in diagnostic sensing

         12. Development of immunoassays for protein analysis on nanobioarray chips

              Lee and P. C. H. Li, Simon Fraser University, Canada

         13. Integrated microfluidic systems for genetic analysis

             Zhuang, W. Gan and P. Liu, Tsinghua University, China

         14. Low-cost assays in paper-based microfluidic biomedical devices

            Benhabib, San Francisco, USA and X.J. Li, University of Texas at El Paso, USA

         15. Microfluidic devices for viral detection

             Sun and X. Jiang, National Center for Nanoscience and Technology, China

         16. Microfluidics for monitoring and imaging pancreatic islets and β-cells

            Wang and J. E. Mendoza-Elias, University of Illinois at Chicago, USA 

         17. Microfluidic devices for radio chemical synthesis

            Y. Lebedev, Siemens Molecular Imaging Biomarker Research, USA