News Ticker

Journals

 


no spine minimum. full size. Editor: Nella JEM: Esther RTP: Erin DaltonAnalytical ChemistryJournal_Biomaterials BiomaterialsJournal_BMD Biomedical MicrodevicesJournal_BMF Biomicrofluidics176 spine minimum. full size. Editor: Lingling JEM: Leslie RTP: Michael Reid JACS
Journal_Cytometry_bCytometry AJournal_Microsystem Microsystem TechnologiesJournal_MNMicro-Nanosystems Journal_MNFMicro/Nanofluidics Journal_Sensor_ASensors and Actuators A
Journal_Sensors_BSensors and Actuators BJournal_LabChip Lab ChipJournal_JMM JMM Micromachine MicroNano

RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • Microfluidic acoustic sawtooth metasurfaces for patterning and separation using traveling surface acoustic waves
    by Mingxin Xu on December 3, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00711D, PaperMingxin Xu, Peter V. S. Lee, David J. CollinsWe demonstrate microfluidic acoustic sawtooth-like metasurfaces that create steerable acoustofluidic fields for microscale patterning and separation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Active single cell encapsulation using SAW overcoming the limitations of Poisson distribution
    by Andreas Link on December 2, 2021 at 12:00 am

    Lab Chip, 2022, Accepted ManuscriptDOI: 10.1039/D1LC00880C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andreas Link, John S McGrath, Mustafa Zaimagaoglu, Thomas FrankeWe demonstrate the use of an acoustic device to actively encapsulate single red blood cells into individual droplets in a T-junction. We compare the active encapsulation with the passive encapsulation...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic organ-on-chip system for multi-analyte monitoring of metabolites in 3D cell cultures
    by Johannes Dornhof on December 1, 2021 at 12:00 am

    Lab Chip, 2022, Advance ArticleDOI: 10.1039/D1LC00689D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Johannes Dornhof, Jochen Kieninger, Harshini Muralidharan, Jochen Maurer, Gerald A. Urban, Andreas WeltinAn organ-on-chip platform equipped with microsensors for long-term microfluidic cultivation and metabolic monitoring (O2, Glu, Lac) of 3D tumour organoid cultures grown from patient-derived single cancer stem cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]

  • Assessing Red Blood Cell Deformability using Deep Learning
    by Erik S. Lamoureux on December 1, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC01006A, CommunicationErik S. Lamoureux, Emel Islamzada, Matthew V.J. Wiens, Kerryn Matthews, Simon P. Duffy, Hongshen MaRed blood cells (RBCs) must be highly deformable to transit through the microvasculature to deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural aging, or storage...The content of this RSS Feed (c) The Royal Society of Chemistry

  • ELECTRONIC MEASUREMENT OF CELL ANTIGEN EXPRESSION IN WHOLE BLOOD
    by Ozgun Civelekoglu on November 30, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00889G, PaperOzgun Civelekoglu, Ruxiu Liu, Can Firat Usanmaz, Chia-Heng Chu, Mert Boya, Tevhide Ozkaya-Ahmadov, A K M Arifuzzman, Ningquan Wang, A. Fatih SariogluMembrane antigens are phenotypic signatures of cells used for distinguishing various subpopulations and therefore, are of great interest for diagnosis diseases and monitoring of patient in hematology and oncology. Existing...The content of this RSS Feed (c) The Royal Society of Chemistry

  • INTERSTITIAL FLOW ENHANCES FORMATION, CONNECTIVITY, AND FUNCTION OF 3D BRAIN MICROVASCULAR NETWORKS GENERATED WITHIN MICROFLUIDIC DEVICE
    by Max A Winkelman on November 30, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00605C, PaperMax A Winkelman, Diana Y Kim, Shravani Kakarla, Alexander Grath, Nathaniel Silvia, Guohao DaiThe convective transport of fluid through tissue is an important factor in human biology, including the development of brain microvascular networks (MVNs) with a functional blood-brain barrier (BBB). Engineering a...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Non-contact-based determination of membrane permeability to water and dimethyl sulfoxide of cells virtually trapped in a self-induced micro-vortex
    by Hsiu-Yang Tseng on November 29, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00846C, PaperHsiu-Yang Tseng, Chiu-Jen Chen, Zong-Lin Wu, Yong-Ming Ye, Guo-Zhen HuangCell-membrane permeability to water (Lp) and cryoprotective agents (Ps) of a cell type is a crucial cellular information for achieving optimal cryopreservation in the biobanking industry. In this work, a...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Intestinal Explant Barrier Chip: long-term intestinal absorption screening in a novel microphysiological system using tissue explants
    by Hossein Eslami Amirabadi on November 29, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00669J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hossein Eslami Amirabadi, Joanne Donkers, Esmée Wierenga, Bastiaan Ingenhut, Lisanne Pieters, Lianne Stevens, Tim Donkers, Joost Westerhout, Rosalinde Masereeuw, Ivana Bobeldijk, Irene Nooijen, Evita van der SteegThe majority of intestinal in vitro screening models use cell lines that do not reflect the complexity of the human intestinal tract and hence often fail to accurately predict intestinal...The […]

  • Immuno-biosensor on a chip: a self-powered microfluidic-based electrochemical biosensing platform for point-of-care quantification of proteins
    by Fatemeh Haghayegh on November 29, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00879J, PaperFatemeh Haghayegh, Razieh Salahandish, Azam Zare, Mahmood Khalghollah, Amir Sanati-NezhadOptimized self-contained microfluidic platform allows for single-step detection of proteins, through passive delivery of the dry-stored reagents required for immunosensing. Novel autonomous performance of the platform advances the point-of-care utilization of electrochemical protein sensing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • High content drug screening of primary cardiomyocytes based on microfluidics and RUSH
    by Liang Huang on November 29, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00740H, PaperLiang Huang, Xu Zhang, Yongxiang Feng, Fei Liang, Wenhui WangHigh content screening (HCS) plays an important role in biological applications, and drug development. Existing techniques fail to simultaneously meet multiple needs of throughput, efficiency in sample and chemical consumption,...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Small intestinal sampling capsule for inflammatory bowel disease type detection and management
    by Sina Nejati on November 26, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00451D, PaperSina Nejati, Jiangshan Wang, Ulisses Heredia-Rivera, Sotoudeh Sedaghat, Ian Woodhouse, Jay S. Johnson, Mohit Verma, Rahim RahimiA non-invasive sampling capsule is introduced to site-selectively collect calprotectin biomarker from the small intestine. This approach can be accompanied with the fecal calprotectin assay to diagnose IBD and differentiate its types (CD and UC).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Manipulation of cancer cells in a sessile droplet via travelling surface acoustic waves
    by Hyeono Nam on November 25, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00801C, PaperHyeono Nam, Hyung Jin Sung, Jinsoo Park, Jessie S. JeonTSAWs quickly form a tumor spheroid for a drug screening platform.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Plug-and-play polymer microfluidic chips for hydrated, room temperature, fixed-target serial crystallography
    by Deepshika Gilbile on November 25, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00810B, PaperDeepshika Gilbile, Megan L. Shelby, Artem Y. Lyubimov, Jennifer L. Wierman, Diana C. F. Monteiro, Aina E. Cohen, Silvia Russi, Matthew A. Coleman, Matthias Frank, Tonya L. KuhlThis work presents our development of versatile, inexpensive, and robust polymer microfluidic chips for routine and reliable room temperature serial X-ray crystallography measurements.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Lymphangion-chip: a microphysiological system which supports co-culture and bidirectional signaling of lymphatic endothelial and muscle cells
    by Amirali Selahi on November 23, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00720C, PaperAmirali Selahi, Teshan Fernando, Sanjukta Chakraborty, Mariappan Muthuchamy, David C. Zawieja, Abhishek JainA microphysiological system of a lymphatic vessel is presented recapitulating crosstalk of lymphatic endothelial and muscle cells co-cultured cylindrically using a unique gravitational lumen patterning technique.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Bridging the gap between development of point-of-care nucleic acid testing and patient care for sexually transmitted infections
    by Kuangwen Hsieh on November 22, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00665G, Critical ReviewKuangwen Hsieh, Johan H. Melendez, Charlotte A Gaydos, Jeff Tza-Huei WangThe rate of sexually transmitted infections (STIs), including the four major curable STIs – chlamydia, gonorrhea, trichomoniasis and, syphilis – continue to increase globally, causing medical cost burden and morbidity...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Spatial Trans-Epithelial Electrical Resistance (S-TEER) Integrated in Organs-on-Chips
    by Noa Renous on November 22, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00789K, PaperNoa Renous, Mark Dan Kiri, Ronny Aharon Barnea, Rossana Rauti, Yael Leichtamnn-Bardoogo , Ben MaozTransepithelial/transendothelial electrical resistance (TEER) is a label-free assay that is commonly used to assess tissue barrier integrity. TEER measurement systems have been embedded in Organ-on-a-Chip devices to provide live readouts...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Selective, User-friendly, Highly Porous, Efficient, and Rapid (SUPER) Filter for Isolation and Analysis of Rare Tumor Cells
    by Kaifeng Zhao on November 22, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00886B, PaperKaifeng Zhao, Yaoping Liu, Hua Wang, Yanling Song, Xiao-Feng Chen, Chen Huang, Qi Niu, Jiao Cao, Xin Chen, Chaoyong James Yang, Wei Wang, Lingling WuRapid, efficient, and selective separation of tumor cells from complex body fluids is urgently needed for clinical application of tumor-cell-based liquid biopsy. Herein, a size-selective affinity filtration system, named Selective,...The content of this RSS Feed (c) The Royal Society of Chemistry

  • A multi-functional microfluidic device compatible with widefield and light sheet microscopy
    by Regan P. Moore on November 22, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00600B, PaperRegan P. Moore, Ellen C. O'Shaughnessy, Yu Shi, Ana T. Nogueira, Katelyn M. Heath, Klaus M. Hahn, Wesley R. LegantFEP-based microfluidics enable diverse applications in light sheet microscopy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Neural network-enhanced real-time impedance flow cytometry for single-cell intrinsic characterization
    by Yongxiang Feng on November 22, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00755F, PaperYongxiang Feng, Zhen Cheng, Huichao Chai, Weihua He, Liang Huang, Wenhui WangWe propose to employ NN-enhanced IFC to achieve both real-time single-cell intrinsic characterization and intrinsic metric-based cell classification at high throughput.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Multiphysics Microfluidics for Cell Manipulation and Separation: A Review
    by HAOTIAN CHA on November 19, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00869B, Critical ReviewHAOTIAN CHA, Hedieh Fallahi, Yuchen Dai, Dan Yuan, Hongjie An, Nam-Trung Nguyen, Jun ZhangMultiphysics microfluidics, which combines multiple functional physics in a microfluidic platform, is an emerging research area that attracts increasing interest in diverse biomedical applications. Multiphysics microfluidics is expected to overcome...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fabrication of Sharp-edged 3D microparticles via folded PDMS microfluidic channels
    by Chenchen Zhou on November 18, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00807B, PaperChenchen Zhou, Shuaishuai Liang, Yongjian Li, Haosheng Chen, Jiang Li3D microparticles have promising applications in self-assembly, biomedical engineering, mechanical engineering, etc. The shape of microparticles plays a significant role in their functionalities. Although numerous investigations have been conducted to...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Dual-frequency impedance assays for intracellular components in microalgal cells
    by Tao Tang on November 18, 2021 at 12:00 am

    Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00721A, PaperTao Tang, Xun Liu, yapeng Yuan, Ryota Kiya, Yigang Shen, TIANLONG ZHANG, Kengo Suzuki, Ming Li, Yo Tanaka, Yoichiroh Hosokawa, Yalikun YaxiaerIntracellular components (including organelles and biomolecules) at the submicron level are typically analyzed in situ by special preparation or expensive setups. Here, a label-free and cost-effective approach of screening microalgal...The content of this RSS Feed (c) The Royal Society of Chemistry

  • ATR-Spin: an open-source 3D printed device for direct cytocentrifugation onto attenuated total reflectance crystals
    by David Pérez-Guaita on November 18, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00813G, CommunicationDavid Pérez-Guaita, Zack Richardson, Guillermo Quintás, Julia Kuligowski, Diana E. Bedolla, Hugh J. Byrne, Bayden WoodThe 3d printed system presented integrates isolation, preconcentration, and measurement of infrared spectra of cells from biofluids, enabling enhanced specific infrared spectra of cells down to 10 cells μL−1.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A method of sequential liquid dispensing for the multiplexed genetic diagnosis of viral infections in a microfluidic device
    by Daigo Natsuhara on November 16, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00829C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Daigo Natsuhara, Ryogo Saito, Hiroka Aonuma, Tatsuya Sakurai, Shunya Okamoto, Moeto Nagai, Hirotaka Kanuka, Takayuki ShibataWe developed a microfluidic flow control theory to provide design guidelines for multiplexed genetic diagnostic devices capable of sequential dispensing of samples into an array of reaction microchambers in a single operation.To cite this article before page numbers are assigned, use the DOI form of […]

  • Point-of-care diagnostics: recent developments in a pandemic age
    by Harshit Harpaldas on November 15, 2021 at 12:00 am

    Lab Chip, 2021, 21,4517-4548DOI: 10.1039/D1LC00627D, Critical ReviewHarshit Harpaldas, Siddarth Arumugam, Chelsey Campillo Rodriguez, Bhoomika Ajay Kumar, Vivian Shi, Samuel K. SiaThis article reviews the rapid and unprecedented development, scaleup and deployment of POC devices in response to the COVID-19 pandemic and its implications for the future of diagnostics and digital health.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Automatic and multi-channel detection of bacteria on a slidable centrifugal disc based on FTA card nucleic acid extraction and recombinase aided amplification
    by Siyuan Wang on November 11, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00915J, PaperSiyuan Wang, Gaozhe Cai, Hong Duan, Wuzhen Qi, Jianhan LinThis study developed a slidable centrifugal disc for automatic and multi-channel detection of Salmonella using FTA card for DNA extraction and RAA for DNA detection and verified it could detect 10 CFU mL−1 in chicken meat supernatant in 1 h.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Interfacing droplet microfluidics with antibody barcodes for multiplexed single-cell protein secretion profiling
    by Tahereh Khajvand on November 11, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00567G, PaperTahereh Khajvand, Peifeng Huang, Linmei Li, Mingxia Zhang, Fengjiao Zhu, Xing Xu, Mengjiao Huang, Chaoyong Yang, Yao Lu, Zhi ZhuMultiplexed single-cell protein secretion profiling has been realized on an integrated microfluidic platform. The secreted proteins from each individual cell are captured by specific pre-patterned antibody sites and detected by off-chip ELISA.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Rapid prototyping of cell culture microdevices using parylene-coated 3D prints
    by Brian J. O'Grady on November 10, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00744K, PaperBrian J. O'Grady, Michael D. Geuy, Hyosung Kim, Kylie M. Balotin, Everett R. Allchin, David C. Florian, Neelansh N. Bute, Taylor E. Scott, Gregory B. Lowen, Colin M. Fricker, Matthew L. Fitzgerald, Scott A. Guelcher, John P. Wikswo, Leon M. Bellan, Ethan S. LippmannParylene deposition on 3D prints creates biocompatible microdevices and facilitates fabrication of master molds.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Automated optimization of endoderm differentiation on chip
    by Jessi Carolina Ardila Riveros on November 9, 2021 at 12:00 am

    Lab Chip, 2021, 21,4685-4695DOI: 10.1039/D1LC00565K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jessi Carolina Ardila Riveros, Anna Karolina Blöchinger, Scott Atwell, Michel Moussus, Nina Compera, Omid Rajabnia, Tihomir Georgiev, Heiko Lickert, Matthias MeierHere we developed an automated mLSI chip platform with general analytical workflow for 3D stem cell cultures offers the optimization of in vitro generation of various cell types for cell replacement therapies.The content of this RSS Feed (c) The Royal […]

  • A vacuum-assisted, highly parallelized microfluidic array for performing multi-step digital assays
    by Jiumei Hu on November 8, 2021 at 12:00 am

    Lab Chip, 2021, 21,4716-4724DOI: 10.1039/D1LC00636C, PaperJiumei Hu, Liben Chen, Pengfei Zhang, Kuangwen Hsieh, Hui Li, Samuel Yang, Tza-Huei WangWe developed a facile PDMS-based, vacuum-assisted microfluidic device that can perform multi-step and multi-reagent digital assays.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Amplification factor in DC insulator-based electrokinetic devices: a theoretical, numerical, and experimental approach to operation voltage reduction for particle trapping
    by Rodrigo Ruz-Cuen on November 5, 2021 at 12:00 am

    Lab Chip, 2021, 21,4596-4607DOI: 10.1039/D1LC00614B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rodrigo Ruz-Cuen, J. Martin de los Santos-Ramírez, Braulio Cardenas-Benitez, Cinthia J. Ramírez-Murillo, Abbi Miller, Kel Hakim, Blanca H. Lapizco-Encinas, Victor H. Perez-GonzalezTrapping voltage in 2D DC-iEK systems was significantly reduced (∼80 V) via a design optimization process primarily focused on E-field amplification.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Cancer drug screening with an on-chip multi-drug dispenser in digital microfluidics
    by Jiao Zhai on November 2, 2021 at 12:00 am

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00895A, PaperJiao Zhai, Caiwei Li, Haoran Li, Shuhong Yi, Ning Yang, Kai Miao, Chuxia Deng, Yanwei Jia, Pui-In Mak, Rui P. MartinsA digital microfluidic system with an innovative control structure and chip design to generate concentrations that span three to four orders of magnitude for single or multi-drug dispensing was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic chip with a serpentine channel enabling high-throughput cell separation using surface acoustic waves
    by Shupeng Ning on November 1, 2021 at 12:00 am

    Lab Chip, 2021, 21,4608-4617DOI: 10.1039/D1LC00840D, PaperShupeng Ning, Shuchang Liu, Yunjie Xiao, Guanyu Zhang, Weiwei Cui, Mark ReedWe demonstrate a label-free, high-throughput cell separation method via a SSAW-based acoustofluidic device with a serpentine channel for clinical diagnosis and point-of-care analysis.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Screening for cerebral amyloid angiopathy based on serological biomarkers analysis using a dielectrophoretic force-driven biosensor platform
    by Hye Jin Kim on November 1, 2021 at 12:00 am

    Lab Chip, 2021, 21,4557-4565DOI: 10.1039/D1LC00742D, PaperHye Jin Kim, Dongsung Park, Gyihyaon Yun, Hongrae Kim, Hyug-Gi Kim, Kyung Mi Lee, Il Ki Hong, Key-Chung Park, Jin San Lee, Kyo Seon HwangScreening of cerebral amyloid angiopathy and Alzheimer's disease by analyzing plasma amyloid-β using a highly sensitive dielectrophoretic force-driven biosensor platform.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Sample-to-analysis platform for rapid intracellular mass spectrometry from small numbers of cells
    by Austin L. Culberson on November 1, 2021 at 12:00 am

    Lab Chip, 2021, 21,4696-4706DOI: 10.1039/D1LC00884F, PaperAustin L. Culberson, Mason A. Chilmonczyk, Peter A. Kottke, Annie C. Bowles-Welch, Delta Ghoshal, Andrei G. FedorovRapid intracellular metabolomics from small numbers of cells.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Generation of programmable dynamic flow patterns in microfluidics using audio signals
    by Peter Thurgood on November 1, 2021 at 12:00 am

    Lab Chip, 2021, 21,4672-4684DOI: 10.1039/D1LC00568E, PaperPeter Thurgood, Gianmarco Concilia, Nhiem Tran, Ngan Nguyen, Adam J. Hawke, Elena Pirogova, Aaron R. Jex, Karlheinz Peter, Sara Baratchi, Khashayar KhoshmaneshWe use a smartphone-driven audio speaker to generate customised harmonic flow patterns in microfluidics. The system is programmable, simple, inexpensive, and biocompatible.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A frugal microfluidic pump
    by Apresio K. Fajrial on October 28, 2021 at 11:00 pm

    Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00691F, PaperApresio K. Fajrial, Adam Vega, Gazendra Shakya, Xiaoyun DingA frugal microfluidic pump is a fluid actuation system that is Fully self-sufficient, RobUst, Gravity-Assisted, and Low-cost (FRUGAL). The pump can generate pressure for versatile microfluidic applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Cortical spheroids display oscillatory network dynamics
    by Jessica L. Sevetson on October 28, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4586-4595DOI: 10.1039/D1LC00737H, PaperJessica L. Sevetson, Brian Theyel, Diane Hoffman-Kim3-D spheroid cultures contain networks that develop by 9 days and develop increasingly complex network activity patterns as they mature. We demonstrate, for the first time, that spheroids exhibit network activity similar to in vivo network events.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Isolation and quantification of extracellular vesicle-encapsulated microRNA on an integrated microfluidic platform
    by Chia-Yu Sung on October 26, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4660-4671DOI: 10.1039/D1LC00663K, PaperChia-Yu Sung, Chi-Chien Huang, Yi-Sin Chen, Keng-Fu Hsu, Gwo-Bin LeeEV extraction, EV-encapsulated microRNA-21 isolation, reverse transcription, and digital PCR for microRNA quantification have been automated on the integrated microfluidic platform.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fully automated light transmission aggregometry on a disc for platelet function tests
    by Chi-Ju Kim on October 26, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4707-4715DOI: 10.1039/D1LC00708D, PaperChi-Ju Kim, Jungmin Kim, Jonathan Sabaté del Río, Dong Yeob Ki, Junyoung Kim, Yoon-Kyoung ChoWe report a fully automated light transmission aggregometry (LTA) assay on a disc that can provide point-of-care testing to assess the function of platelets.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Design and construction of three-dimensional physiologically-based vascular branching networks for respiratory assist devices
    by Jose A. Santos on October 25, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4637-4651DOI: 10.1039/D1LC00287B, PaperJose A. Santos, Alla A. Gimbel, Athanasios Peppas, James G. Truslow, Daniel A. Lang, Sivaprasad Sukavaneshvar, Derek Solt, Thomas J. Mulhern, Alex Markoski, Ernest S. Kim, James C.-M. Hsiao, Diana J. Lewis, Daniel I. Harjes, Christopher DiBiasio, Joseph L. Charest, Jeffrey T. BorensteinMulti-layer microfluidic oxygenator fabricated from three-dimensional branching blood flow networks mimicking physiological vasculature.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A handy reversible bonding technology and its application on fabrication of an on-chip liquid metal micro-thermocouple
    by Jie Hong on October 21, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4566-4573DOI: 10.1039/D1LC00726B, PaperJie Hong, Jiahao Gong, Qian Li, Zhongshan Deng, Lin GuiAn on-chip liquid metal based micro-thermocouple based on a reversible bonding technology.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Optofluidic ptychography on a chip
    by Pengming Song on October 19, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4549-4556DOI: 10.1039/D1LC00719J, CommunicationPengming Song, Chengfei Guo, Shaowei Jiang, Tianbo Wang, Patrick Hu, Derek Hu, Zibang Zhang, Bin Feng, Guoan ZhengWe demonstrate high-resolution ptychographic imaging in a flow cytometer configuration. The device complements the miniaturization provided by microfluidics and allows the integration of ptychographic microscopy into various lab-on-a-chip systems.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Acoustofluidic medium exchange for preparation of electrocompetent bacteria using channel wall trapping
    by M. S. Gerlt on October 19, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4487-4497DOI: 10.1039/D1LC00406A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.M. S. Gerlt, P. Ruppen, M. Leuthner, S. Panke, J. DualComprehensive integration of process steps into a miniaturised version of synthetic biology workflows remains a crucial task in automating the design of biosystems. We present an acoustofluidic chip, capable of automated medium exchange of bacteria.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Programmed assembly of bespoke prototissues on a microfluidic platform
    by Kaitlyn Ramsay on October 18, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4574-4585DOI: 10.1039/D1LC00602A, PaperKaitlyn Ramsay, Jae Levy, Pierangelo Gobbo, Katherine S. ElviraA microfluidic platform to build bespoke prototissues with collective behaviours that depend on the chemical composition of the biomaterial.The content of this RSS Feed (c) The Royal Society of Chemistry

  • High throughput production of microcapsules using microfluidics for self-healing of cementitious materials
    by Lívia Ribeiro de Souza on October 17, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4652-4659DOI: 10.1039/D1LC00569C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lívia Ribeiro de Souza, Abir Al-TabbaaParallel junctions on a modular chip were used to produce high throughput monodisperse microcapsules for self-healing in cementitious materials.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Addressable graphene encapsulation of wet specimens on a chip for optical, electron, infrared and X-ray based spectromicroscopy studies
    by Christopher Arble on October 14, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4618-4628DOI: 10.1039/D1LC00440A, PaperChristopher Arble, Hongxuan Guo, Alessia Matruglio, Alessandra Gianoncelli, Lisa Vaccari, Giovanni Birarda, Andrei KolmakovA microchip for spectromicroscopy of biological materials employs a graphene enclosure to separate hydrated samples from a vacuum environment. Co-encapsulated lithographically defined hydrogel microstructures extend the lifetime of the hydrated state.The content of this RSS Feed (c) The Royal Society of Chemistry

  • An innovative data processing method for studying nanoparticle formation in droplet microfluidics using X-rays scattering
    by Dimitri Radajewski on October 12, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4498-4506DOI: 10.1039/D1LC00545F, PaperDimitri Radajewski, Liam Hunter, Xuefeng He, Ouassef Nahi, Johanna M. Galloway, Fiona C. MeldrumX-ray scattering techniques provide a powerful means of characterizing the formation of nanoparticles in solution.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Preprogrammed microfluidic system for parallel anti-reflection coating by layer-by-layer assembly
    by Zhenglin Li on October 12, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4629-4636DOI: 10.1039/D1LC00556A, PaperZhenglin Li, Bongjun Yeom, Sung-Jin KimWe present a device that can scan and optimize the condition of a nanofilm coating in a parallel and ultrafast manner without using off-chip controllers.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Virus removal from semen with a pinched flow fractionation microfluidic chip
    by T. Hamacher on October 11, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4477-4486DOI: 10.1039/D1LC00643F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.T. Hamacher, J. T. W. Berendsen, J. E. van Dongen, R. M. van der Hee, J. J. L. M. Cornelissen, M. L. W. J. Broekhuijse, L. I. SegerinkPinched-flow fractionation removes viruses from (porcine) semen, which can increase the biosecurity of artificial insemination.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Personalized gel-droplet monocyte vaccines for cancer immunotherapy
    by Yishen Tian on October 11, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4414-4426DOI: 10.1039/D1LC00646K, PaperYishen Tian, Chunmiao Xu, Jiao Feng, Yueyue Huangfu, Kai Wang, Zhi-Ling ZhangPersonalized gel-droplet-encapsulated monocyte vaccines were prepared using an integrated chip and injected back into the hosts to induce CTL for the treatment of cancer.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic platform enables comprehensive gene expression profiling of mouse retinal stem cells
    by Brenda L. K. Coles on October 10, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4464-4476DOI: 10.1039/D1LC00790D, PaperBrenda L. K. Coles, Mahmoud Labib, Mahla Poudineh, Brendan T. Innes, Justin Belair-Hickey, Surath Gomis, Zongjie Wang, Gary D. Bader, Edward H. Sargent, Shana O. Kelley, Derek van der KooyA microfluidic approach combined with single-cell RNA sequencing enabled prospective identification of retinal stem cells and discovery of novel cell-surface markers and transcription factors.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Precise sample metering method by coordinated burst action of hydrophobic burst valves applied to dried blood spot collection
    by Dries Vloemans on October 7, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4445-4454DOI: 10.1039/D1LC00422K, PaperDries Vloemans, Lorenz Van Hileghem, Wannes Verbist, Debby Thomas, Francesco Dal Dosso, Jeroen LammertynNovel passive microfluidic concept for precise volume metering and its use for high quality dried blood spot sample preparation.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Wearable chem-biosensing devices: from basic research to commercial market
    by Bin Yang on October 7, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4285-4310DOI: 10.1039/D1LC00438G, Critical ReviewBin Yang, Xingyu Jiang, Xueen Fang, Jilie KongThis review aims to help readers engage in wearable fundamental research or wearables commercial market by evaluating the biosensing performance.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic droplet-based functional materials for cell manipulation
    by Yajing Zheng on October 5, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4311-4329DOI: 10.1039/D1LC00618E, Critical ReviewYajing Zheng, Zengnan Wu, Ling Lin, Xiaonan Zheng, Ying Hou, Jin-Ming LinThis review focuses on diverse functional materials produced by microfluidic droplet technique and their applications in cell manipulation. It will inspire reader to explore cell biology by developing novel materials from an engineering perspective.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Inside the ensemble: unlocking the potential of one-at-a-time experiments with lab-on-a-chip automation
    by Rob Ward on October 4, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4401-4413DOI: 10.1039/D1LC00601K, PaperRob Ward, Sapna Ravindran, Mariela R. Otazo, Braden Cradock, Ebubekir Avci, Graeme Gillies, Christina Coker, Martin A. K. WilliamsAutomated microfluidics, laser tweezers, particle detection for pairwise particle stickiness measurements.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Muscope: a miniature on-chip lensless microscope
    by Ekta Prajapati on October 4, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4357-4363DOI: 10.1039/D1LC00792K, CommunicationEkta Prajapati, Saurav Kumar, Shishir KumarWe report the Muscope, a miniature lensless holographic microscope suitable for on-chip integration.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic-enabled combinatorial formulation and integrated inkjet printing platform for evaluating functionally graded material blends
    by Anindya Lal Roy on October 3, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4427-4436DOI: 10.1039/D1LC00524C, PaperAnindya Lal Roy, Hsi Nien Chiu, Konrad WalusA novel combinatorial thin film material formulation and deposition platform integrating microfluidic processing and drop-on-demand inkjet patterning capabilities.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Generation of flow and droplets with an ultra-long-range linear concentration gradient
    by Bo Dai on October 3, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4390-4400DOI: 10.1039/D1LC00749A, PaperBo Dai, Yan Long, Jiandong Wu, Shaoqi Huang, Yuan Zhao, Lulu Zheng, Chunxian Tao, Shiwei Guo, Francis Lin, Yongfeng Fu, Dawei Zhang, Songlin ZhuangA concentration gradient generator is demonstrated to generate ultra-long linear gradients, periodic gradients and droplets with various concentrations and produce drugs with different concentrations for drug screening applications.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fluid actuation and buoyancy driven oscillation by enzyme-immobilized microfluidic microcapsules
    by Rohit Varshney on October 1, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4352-4356DOI: 10.1039/D1LC00699A, CommunicationRohit Varshney, Arshdeep Kaur Gill, Mujeeb Alam, Chinmayee Agashe, Debabrata PatraTo mimic the life-like complex behavior of microorganisms, enzyme-immobilized microfluidic microcapsules were fabricated to demonstrate the enzyme powered fluid actuation and buoyancy driven motility.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Three-dimensional tracking of nanoparticles by dual-color position retrieval in a double-core microstructured optical fiber
    by Shiqi Jiang on September 26, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4437-4444DOI: 10.1039/D1LC00709B, PaperShiqi Jiang, Ronny Förster, Adrian Lorenz, Markus A. SchmidtWe report a 3D tracking platform based on dual-color position retrieval in a double-core microstructured optical fiber allowing full 3D reconstruction of the trajectory of a diffusing nanoparticle in a water-filled fiber-integrated microchannel.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Interaction between positive and negative dielectric microparticles/microorganism in optoelectronic tweezers
    by Shuzhang Liang on September 23, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4379-4389DOI: 10.1039/D1LC00610J, PaperShuzhang Liang, Chunyuan Gan, Yuguo Dai, Chaonan Zhang, Xue Bai, Shuailong Zhang, Aaron R. Wheeler, Huawei Chen, Lin FengInteraction between micro-objects is used to achieve the trapping, transport, and release of particles in the OET, enhancing the high-throughput transportation, and also to assemble some special microparticles structures.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Use of some cost-effective technologies for a routine clinical pathology laboratory
    by Mercedes Vázquez on September 23, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4330-4351DOI: 10.1039/D1LC00658D, PerspectiveMercedes Vázquez, Laura Anfossi, Hadar Ben-Yoav, Lorena Diéguez, Thomas Karopka, Bartolomeo Della Ventura, Sara Abalde-Cela, Antonio Minopoli, Fabio Di Nardo, Vikas Kumar Shukla, Alexandra Teixeira, Asta Tvarijonaviciute, Lorena Franco-MartínezCost-effective technologies allow >85% economical savings, making clinical pathology more accessible worldwide.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Dynamic phase control with printing and fluidic materials' interaction by inkjet printing an RF sensor directly on a stereolithographic 3D printed microfluidic structure
    by Eiyong Park on September 19, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4364-4378DOI: 10.1039/D1LC00419K, PaperEiyong Park, Sungjoon LimRF electronics is inkjet-printed directly onto a 3D printed microfluidic structure using surface modification for the high conductivity, high resolution, and enhanced the interaction between a RF part and a fluid material.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Synthetic cellular communication-based screening for strains with improved 3-hydroxypropionic acid secretion
    by Seungjin Kim on September 15, 2021 at 11:00 pm

    Lab Chip, 2021, 21,4455-4463DOI: 10.1039/D1LC00676B, PaperSeungjin Kim, Si Hyung Jin, Hyun Gyu Lim, Byungjin Lee, Jaesung Kim, Jina Yang, Sang Woo Seo, Chang-Soo Lee, Gyoo Yeol JungCellular communication-based screening for strains with improved secretion.The content of this RSS Feed (c) The Royal Society of Chemistry

Analytical Chemistry: Latest Articles (ACS Publications) latest articles published in Analytical Chemistry

    Feed has no items.

Microsystems & Nanoengineering - nature.com technology Microsystems & Nanoengineering is an international open access journal, publishing original articles and reviews covering all aspects of microsystems and nanoengineering from fundamental to applied research.