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RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • All-in-one platform for salivary cotinine detection integrated with a microfluidic channel and an electrochemical biosensor
    by Kyungyeon Lee on December 11, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC01024F, PaperKyungyeon Lee, Taehee Yoon, Hee-seon Yang, Sunyeong Cha, Yong-Pil Cheon, Leila Kashefi-Kheyrabadi, Hyo-Il JungAn all-in-one platform is presented to basically collect the human saliva and directly deliver it onto an electrochemical biosensing surface. Salivary cotinine is accurately analyzed with the aid of the meticulously developed platform.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A self-contained and fully integrated fluidic cassette system for multiplexed nucleic acid detection of bacteriuria
    by Nan Li on December 10, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00994A, PaperNan Li, Ying Lu, Jing Cheng, Youchun XuThe gold standard for diagnosing infectious diseases is culture-based identification of bacterial pathogens, which is time-consuming and labour-intensive. Current advances in molecular diagnostics and microfluidic technologies have made the rapid...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Localized microinjection of intact Drosophila melanogaster larva to investigate the effect of serotonin on heart rate
    by Alireza Zabihihesari on December 10, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00963A, PaperAlireza Zabihihesari, Arthur J. Hilliker, Pouya RezaiIntact-larva Drosophila microinjection with spatial precision was achieved using a microfluidic chip. Effect of serotonin on heartrate was characterized semi-automatically.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Three-dimensional microfluidic tape-paper-based sensing device for blood total bilirubin measurement in jaundiced neonates
    by Weirui Tan on December 10, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00939F, PaperWeirui Tan, Liyuan Zhang, James Doery, Wei ShenMore than 60 % newborns experience hyperbilirubinemia and jaundice within the initial week after birth due to the accumulation of total bilirubin in blood. Left untreated high levels of bilirubin...The content of this RSS Feed (c) The Royal Society of Chemistry

  • A Microelectrode Array Chip for Osteogenic Differentiation of Mesenchymal Stem Cells under Electrical Stimulation
    by Tianyang Zheng on December 9, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC01081E, PaperTianyang Zheng, Zhizhong Zhang, Rong Zhu, Dong SunElectrical stimulation (ES) as an easy and effective inducing method has been widely used in induction differentiation of stem cells, e.g. osteogenic differentiation of mesenchymal stem cells (MSCs) for bone...The content of this RSS Feed (c) The Royal Society of Chemistry

  • A Self-Driven Microfluidic Surface-Enhanced Raman Scattering Device for Hg2+ Detection Fabricated by Femtosecond Laser
    by Xiuyun Li on December 6, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00883G, PaperXiuyun Li, Gan Yuan, weili Yu, Jun Xing, Yuting Zou, Chen Zhao, Wenchi Kong, Zhi Yu, Chunlei GuoIn this paper, we proposed a new microfluidic device, namely self-driven microfluidic Surface Enhance Raman Spectroscopy (SERS) detection chip, fabricated by femtosecond laser direct writing on Si slides, for quantitative...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Liquid metal electrode-enabled flexible microdroplet sensor
    by Renchang Zhang on December 6, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00995G, PaperRenchang Zhang, Zi Ye, Meng Gao, Chang Gao, Xudong Zhang, Lei Li, Lin GuiThis study presented a flexible liquid metal-based microdroplet capacitive sensor that would simply and accurately measure the speed and length of droplets flowing in the micro-channel. A pair of coplanar...The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic device for both on-chip dialysis protein crystallization and in situ X-ray diffraction
    by Niels Junius on December 5, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00651F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Niels Junius, Sofia Jaho, Yoann Sallaz-Damaz, Franck Borel, Jean-Baptiste Salmon, Monika Budayova-SpanoThis paper reports a versatile microfluidic chip developed for on-chip crystallization of proteins through the dialysis method and in situ X-ray diffraction experiments.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]

  • Dynamically tunable elasto-inertial particle focusing and sorting in microfluidics
    by Yinning Zhou on December 5, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC01071H, PaperYinning Zhou, Zhichao Ma, Ye AiInertial particle separation using passive hydrodynamic forces has obtained great attention in the microfluidics community because of its operation simplicity and high throughput sample processing. Due to the passive nature...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Ultra-simple wearable local sweat volume monitoring patch based on swellable hydrogels
    by F. J. Zhao on December 4, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00911F, PaperF. J. Zhao, M. Bonmarin, Z. C. Chen, M. Larson, D. Fay, D. Runnoe, J. HeikenfeldPresented is an ultra-simple wearable local sweat volume monitoring patch based on swellable hydrogels.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Fluid displacement during droplet formation at microfluidic flow-focusing junctions
    by Haishui Huang on December 4, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC90130B, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Haishui Huang, Xiaoming HeTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Inertial microfluidic cube for automatic and fast extraction of white blood cells from whole blood
    by Shu Zhu on December 4, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00942F, PaperShu Zhu, Wu Dan, Yu Han, Cailian Wang, Nan Xiang, Zhonghua NiWe report here a novel inertial microfluidic (IM) cube integrated with the lysis, storage and extraction modules for extracting white blood cells (WBCs) from whole blood automatically, harmlessly and quickly....The content of this RSS Feed (c) The Royal Society of Chemistry

  • Sensitive Tear Screening of Diabetic Retinopathy with Dual Biomarkers Enabled by a Rapid Electrokinetic Patterning Platform
    by Jen-Yi Wang on December 4, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00975B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Jen-Yi Wang, Jae-Sung Kwon, Sheng-Min Hsu, Han-Sheng ChuangBead-based immunosesnors have been intriguing the scientific community over the past decades due to their rapid and multiplexed capabilities in the detection of various biological targets. Nevertheless, their use in...The content of this RSS Feed (c) The Royal Society of Chemistry

  • PDMS filter structures for size-dependent larval sorting and on-chip egg extraction of C. elegans
    by Huseyin Baris Atakan on November 28, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00949C, PaperHuseyin Baris Atakan, Furkan Ayhan, Martin A. M. GijsWe present a microfluidic device for rapid larvae sorting and on-chip egg extraction of C. elegans at high purity and high throughput.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Multiscale 3D-printing of microfluidic AFM cantilevers
    by Robert C. L. N. Kramer on November 28, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00668K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Robert C. L. N. Kramer, Eleonoor J. Verlinden, Livia Angeloni, Anita van den Heuvel, Lidy E. Fratila-Apachitei, Silvère M. van der Maarel, Murali K. GhatkesarMultiscale 3D-printing enables rapid prototyping and fabrication of microfluidic AFM cantilevers for applications in life sciences and beyond.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]

  • Deformability based sorting of stored red blood cells reveals donor-dependent aging curves
    by Emel Islamzada on November 28, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC01058K, CommunicationEmel Islamzada, Kerryn Matthews, Quan Guo, Aline T. Santoso, Simon P. Duffy, Mark D. Scott, Hongshen MaCell sorting using microfluidic ratchets enables sensitive and consistent characterization of donor red blood cell deformability. Using this capability, we show the degradation of red blood cell deformability during cold storage is donor-dependent.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Gravity-driven microfluidic assay for digital enumeration of bacteria and for antibiotic susceptibility testing
    by Yu-Ting Kao on November 27, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00684B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yu-Ting Kao, Tomasz S. Kaminski, Witold Postek, Jan Guzowski, Karol Makuch, Artur Ruszczak, Felix von Stetten, Roland Zengerle, Piotr GarsteckiEasy-to-use gravity-driven step emulsification devices are capable of digital enumeration of bacteria and antibiotic susceptibility testing within 5 hours.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]

  • Wireless, passive strain sensor in a doughnut-shaped contact lens for continuous non-invasive self-monitoring of intraocular pressure
    by M. Hossein M. Kouhani on November 26, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00735K, PaperM. Hossein M. Kouhani, Jiajia Wu, Arman Tavakoli, Arthur J. Weber, Wen LiGlaucoma is a leading cause of blindness and real-time monitoring of intraocular pressure is of great demand. We present a stretchable sensor inside a contact lens capable of monitoring change in the curvature of cornea caused by IOP fluctuations.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Soft temperature-responsive microgels of complex shape in stop-flow lithography
    by Hanna J. M. Wolff on November 26, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00749K, PaperHanna J. M. Wolff, John Linkhorst, Tim Göttlich, Johann Savinsky, Andreas J. D. Krüger, Laura de Laporte, Matthias WesslingUsing a NIPAm monomer with a crosslinker in stop-flow lithography enables the fabrication of soft, temperature-responsive microgels of complex shape.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Hierarchical micro/nanoporous ion-exchangeable sponge
    by Jihye Choi on November 25, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00919A, PaperJihye Choi, Hyomin Lee, Sung Jae KimThe hierarchical micro/nanoporous sponge can desalt and neutralize a water source by squeezing the sponge in a single hand grip.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A tunable filter for high molecular weight DNA selection and linked-read sequencing
    by Nicolas Milon on November 25, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00965E, PaperNicolas Milon, Juan-Luis Fuentes Rojas, Adrien Castinel, Laurent Bigot, Géraud Bouwmans, Karen Baudelle, Audrey Boutonnet, Audrey Gibert, Olivier Bouchez, Cécile Donnadieu, Frédéric Ginot, Aurélien BancaudIn third generation sequencing, long DNA molecules of more than ∼20 kbp are needed to obtain quality sequence data. Here we report a versatile technology for DNA size selection that fulfills this requirement.To cite this article before page numbers are assigned, use the DOI form of citation […]

  • High-throughput Single-cell Cultivation Reveals Underexplored Rare Biosphere in Deep-sea Sediments Along the Southwest Indian Ridge
    by Beiyu Hu on November 25, 2019 at 12:00 am

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00761J, PaperBeiyu Hu, Bingxue Xu, Juanli Yun, Jian Wang, Caiming Li, Bingliang Xie, Yanghuan Yu, Ying Lan, Yaxin Zhu, Xin Dai, Ying Huang, Li Huang, Jian-Zhang Pan, Wenbin DuMicroorganisms in the deep sea play vital roles in marine ecosystems. However, despite great advances brought by high throughput sequencing and metagenomics, only a small portion of microorganisms living in...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Development and evaluation of inexpensive automated deep learning-based imaging systems for embryology
    by Manoj Kumar Kanakasabapathy on November 22, 2019 at 12:00 am

    Lab Chip, 2019, 19,4139-4145DOI: 10.1039/C9LC00721K, PaperManoj Kumar Kanakasabapathy, Prudhvi Thirumalaraju, Charles L. Bormann, Hemanth Kandula, Irene Dimitriadis, Irene Souter, Vinish Yogesh, Sandeep Kota Sai Pavan, Divyank Yarravarapu, Raghav Gupta, Rohan Pooniwala, Hadi ShafieeArtificial intelligence enabled inexpensive imaging hardware can be a valuable tool for reliable embryo assessments in in vitro fertilization.The content of this RSS Feed (c) The Royal Society of Chemistry

  • smFISH in chips: a microfluidic-based pipeline to quantify in situ gene expression in whole organisms
    by Jason Wan on November 22, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00896A, PaperJason Wan, Gongchen Sun, Jocelyn Dicent, Dhaval S. Patel, Hang LuMicrofluidic platform to couple live imaging with smFISH in whole organisms to link phenotypes to gene expression.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Contactless sensing of liquid marbles for detection, characterisation & computing
    by Thomas C. Draper on November 21, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC01001G, PaperThomas C. Draper, Neil Phillips, Roshan Weerasekera, Richard Mayne, Claire Fullarton, Ben P. J. de Lacy Costello, Andrew AdamatzkyNew liquid marble sensor exploits impedance to detect presence of liquid marbles, whilst also providing characterisation information.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Parallelizable microfluidic dropmakers with multilayer geometry for the generation of double emulsions
    by Saraf Nawar on November 21, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00966C, PaperSaraf Nawar, Joshuah K. Stolaroff, Congwang Ye, Huayin Wu, Du Thai Nguyen, Feng Xin, David A. WeitzWe present a multilayer dropmaker geometry that enables the modular fabrication of microfluidic devices containing precisely patterned channel surface wettability. The platform is used for the scalable production of uniform double emulsion drops.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry
    by Andreas R. Baudy on November 20, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00768G, Critical ReviewAndreas R. Baudy, Monicah A. Otieno, Philip Hewitt, Jinping Gan, Adrian Roth, Douglas Keller, Radhakrishna Sura, Terry R. Van Vleet, William R. ProctorThis pharmaceutical industry guidance based on a 3-staged benchmarking strategy aims to help MPS developers and end users identify what could be the most valuable models for safety risk assessment, as well as provide an overview of contexts of use.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]

  • Soft, skin-interfaced microfluidic systems with integrated enzymatic assays for measuring the concentration of ammonia and ethanol in sweat
    by Sung Bong Kim on November 20, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC01045A, PaperSung Bong Kim, Jahyun Koo, Jangryeol Yoon, Aurélie Hourlier-Fargette, Boram Lee, Shulin Chen, Seongbin Jo, Jungil Choi, Yong Suk Oh, Geumbee Lee, Sang Min Won, Alexander J. Aranyosi, Stephen P. Lee, Jeffrey B. Model, Paul V. Braun, Roozbeh Ghaffari, Chulwhan Park, John A. RogersSoft microfluidics with reference reactions enable quantitative sweat ammonia–ethanol assay.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Combining dielectrophoresis and computer vision for precise and fully automated single-cell handling and analysis
    by Neus Godino on November 20, 2019 at 12:00 am

    Lab Chip, 2019, 19,4016-4020DOI: 10.1039/C9LC00800D, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Neus Godino, Felix Pfisterer, Tobias Gerling, Christian Guernth-Marschner, Claus Duschl, Michael KirschbaumWe employ real-time image processing in the active control of dielectrophoretic actuation to select, isolate and arrange individual cells in a microfluidic channel.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Electrochemical paper-based devices: sensing approaches and progress toward practical applications
    by Eka Noviana on November 19, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC90124H, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Eka Noviana, Cynthia P. McCord, Kaylee M. Clark, Ilhoon Jang, Charles S. HenryTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Separation-encoded microparticles for single-cell western blotting
    by Burcu Gumuscu on November 15, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00917E, PaperBurcu Gumuscu, Amy E. HerrSingle-cell protein analysis via separations-encoded microparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic system for Caenorhabditis elegans culture and oxygen consumption rate measurements
    by Roger Krenger on November 15, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00829B, PaperRoger Krenger, Matteo Cornaglia, Thomas Lehnert, Martin A. M. GijsMicrofluidic C. elegans culture chamber with integrated oxygen sensing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Blood platelet enrichment in mass-producible surface acoustic wave (SAW) driven microfluidic chips
    by Cynthia Richard on November 14, 2019 at 12:00 am

    Lab Chip, 2019, 19,4043-4051DOI: 10.1039/C9LC00804G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Cynthia Richard, Armaghan Fakhfouri, Melanie Colditz, Friedrich Striggow, Romy Kronstein-Wiedemann, Torsten Tonn, Mariana Medina-Sánchez, Oliver G. Schmidt, Thomas Gemming, Andreas WinklerSAW-based acoustofluidic blood platelet separation at 2.7 × 104 cells per s throughput in a comprehensively analysed and numerical simulated, wafer-scale manufactured device.The content of this RSS Feed (c) The Royal […]

  • Cell lysis via acoustically oscillating sharp edges
    by Zeyu Wang on November 13, 2019 at 12:00 am

    Lab Chip, 2019, 19,4021-4032DOI: 10.1039/C9LC00498J, PaperZeyu Wang, Po-Hsun Huang, Chuyi Chen, Hunter Bachman, Shuaiguo Zhao, Shujie Yang, Tony J. HuangShear stress induced by acoustic vibrating sharp edges lyse cells mechanically.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Digital quantification and selection of high-lipid-producing microalgae through a lateral dielectrophoresis-based microfluidic platform
    by Song-I Han on November 13, 2019 at 12:00 am

    Lab Chip, 2019, 19,4128-4138DOI: 10.1039/C9LC00850K, PaperSong-I Han, Hyun Soo Kim, Ki-Ho Han, Arum HanDEP-based microfluidic platform enables microalgae digital quantification based on intracellular lipid level and selective collection of high-lipid-producing microalgae from a library.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Quantifying the sol–gel process and detecting toxic gas in an array of anchored microfluidic droplets
    by Laurent Mugherli on November 12, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00750D, PaperLaurent Mugherli, Adelaide Lety-Stefanska, Nina Landreau, Raphael F.-X. Tomasi, Charles N. BaroudThe production of sol–gel beads, in situ within a microfluidic device, allows us to study the sol–gel transition with exquisite detail, as well measuring the presence of toxic gases using microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Analyte transport to micro- and nano-plasmonic structures
    by N. Scott Lynn on November 12, 2019 at 12:00 am

    Lab Chip, 2019, 19,4117-4127DOI: 10.1039/C9LC00699K, PaperN. Scott Lynn, Tomáš Špringer, Jiří Slabý, Barbora Špačková, Michaela Gráfová, Maria Laura Ermini, Jiří HomolaWe examine analyte transport to numerous plasmonic micro- and nano-structures having variable fill fraction, and via sensorgram analysis (ssDNA detection), we show that measured rates of transport match well to a simple theoretical model.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Degassed micromolding lithography for rapid fabrication of anisotropic hydrogel microparticles with high-resolution and high uniformity
    by Hyeon Ung Kim on November 8, 2019 at 12:00 am

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/C9LC00828D, PaperHyeon Ung Kim, Yong Jun Lim, Hyun Jee Lee, Nak Jun Lee, Ki Wan BongDegassed micromolding lithography is developed to load precursors into the micromold regardless of the wettability and synthesize homogeneous hydrogel microparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic alternating-pull–push active digitization method for sample-loss-free digital PCR
    by Xin Zhou on November 6, 2019 at 12:00 am

    Lab Chip, 2019, 19,4104-4116DOI: 10.1039/C9LC00932A, PaperXin Zhou, Gopi Chandran Ravichandran, Peng Zhang, Yang Yang, Yong ZengA robust microfluidic alternating-pull–push active digitization method based on pneumatic valve actuation enables reproducible and highly efficient digitization of small-volume samples for dPCR.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic retention of progressively motile zebrafish sperms
    by Bivas Panigrahi on November 5, 2019 at 12:00 am

    Lab Chip, 2019, 19,4033-4042DOI: 10.1039/C9LC00534J, PaperBivas Panigrahi, Chia-Yuan ChenA microfluidic concept was demonstrated for the orientation control of progressively motile zebrafish sperms through the hydrodynamic manipulation.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Gradient-sized control of tumor spheroids on a single chip
    by Guocheng Fang on November 4, 2019 at 12:00 am

    Lab Chip, 2019, 19,4093-4103DOI: 10.1039/C9LC00872A, PaperGuocheng Fang, Hongxu Lu, Andrew Law, David Gallego-Ortega, Dayong Jin, Gungun LinGradient-sized spheroids can be simultaneously generated on a single chip using a liquid-dome method assisted by the surface tension. The facile method can be used for investigation of the size-dependent behaviors of spheroids in biomedical research.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Retooling phage display with electrohydrodynamic nanomixing and nanopore sequencing
    by Lyndon J. Raftery on October 31, 2019 at 12:00 am

    Lab Chip, 2019, 19,4083-4092DOI: 10.1039/C9LC00978G, PaperLyndon J. Raftery, Christopher B. Howard, Yadveer S. Grewal, Ramanathan Vaidyanathan, Martina L. Jones, Will Anderson, Darren Korbie, Tania Duarte, Minh Duc Cao, Son Hoang Nguyen, Lachlan J. M. Coin, Stephen M. Mahler, Matt TrauHigh throughput screening of phage display libraries for target binding molecules using electrohydrodynamic nanomixing and nanopore sequencing.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fabrication and verification of a glass–silicon–glass micro-/nanofluidic model for investigating multi-phase flow in shale-like unconventional dual-porosity tight porous media
    by Yandong Zhang on October 31, 2019 at 12:00 am

    Lab Chip, 2019, 19,4071-4082DOI: 10.1039/C9LC00847K, PaperYandong Zhang, Chuanle Zhou, Chuang Qu, Mingzhen Wei, Xiaoming He, Baojun BaiA time efficient and costless lift-off process combined with the anodic bonding method was used to create a ‘shale-like’ glass–silicon–glass microfluidic model.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Controllable cell manipulation in a microfluidic pipette-tip design using capacitive coupling of electric fields
    by Terje Wimberger on October 31, 2019 at 12:00 am

    Lab Chip, 2019, 19,3997-4006DOI: 10.1039/C9LC00927B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Terje Wimberger, Johannes R. Peham, Eva-Kathrin Ehmoser, Klemens J. WassermannCapacitive coupling of electric fields diminishes energy dissipation and offers superior control over field parameters, resulting in predictable biological outcomes.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Rapid additive-free bacteria lysis using traveling surface acoustic waves in microfluidic channels
    by Haiwei Lu on October 30, 2019 at 12:00 am

    Lab Chip, 2019, 19,4064-4070DOI: 10.1039/C9LC00656G, PaperHaiwei Lu, Kirk Mutafopulos, John A. Heyman, Pascal Spink, Liang Shen, Chaohui Wang, Thomas Franke, David A. WeitzWe introduce a microfluidic device that uses traveling surface acoustic waves to lyse bacteria with high efficiency. This lysis method should be applicable to a wide range of bacteria species and can be modified to analyze individual bacteria cells.The content of this RSS Feed (c) The Royal Society of Chemistry

  • The acoustofluidic focusing and separation of rare tumor cells using transparent lithium niobate transducers
    by Zezheng Wu on October 21, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3922-3930DOI: 10.1039/C9LC00874H, PaperZezheng Wu, Hongqiang Jiang, Lingling Zhang, Kezhen Yi, Heng Cui, Fubing Wang, Wei Liu, Xingzhong Zhao, Fuling Zhou, Shishang GuoResearch on circulating tumor cells (CTCs) is of great significance in cancer diagnosis, prognosis and even the development of personalized therapy.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microelectrofluidic probe for sequential cell separation and patterning
    by Ayoola T. Brimmo on October 21, 2019 at 11:00 pm

    Lab Chip, 2019, 19,4052-4063DOI: 10.1039/C9LC00748B, PaperAyoola T. Brimmo, Anoop Menachery, Mohammad A. QasaimehCell separation and patterning are of great interest to numerous biomedical applications. This work presents the microelectrofluidic probe, which separates cells within an open microfluidic system, and patterns cells in a 2D printing approach.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Real-time pressure monitoring system for microfluidic devices using deformable colloidal crystal membrane
    by Jang Han Choi on October 18, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3954-3961DOI: 10.1039/C9LC00867E, PaperJang Han Choi, Tae Soup ShimReal-time, in situ internal pressure monitoring in a microchannel is realized by a deformable colloidal crystal membrane.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfabricated porous layer open tubular (PLOT) column
    by Maxwell Wei-Hao Li on October 17, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3979-3987DOI: 10.1039/C9LC00886A, PaperMaxwell Wei-Hao Li, Jinyan She, Hongbo Zhu, Ziqi Li, Xudong FanDevelopment of a porous layer open tubular micro-column for light volatiles analysis enables broader micro-gas chromatography applicability to on-site environmental protection, industrial monitoring, and toxicology.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Tunable microfluidic device fabricated by femtosecond structured light for particle and cell manipulation
    by Kai Hu on October 17, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3988-3996DOI: 10.1039/C9LC00759H, PaperKai Hu, Liang Yang, Dongdong Jin, Jiawen Li, Shengyun Ji, Chen Xin, Yanlei Hu, Dong Wu, Li Zhang, Jiaru ChuA tunable microfluidic device for complete particle trapping was realized by integrating a pH-sensitive hydrogel microring array via femtosecond structured light.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Origami-paper-based device for microvesicle/exosome preconcentration and isolation
    by Hyerin Kim on October 17, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3917-3921DOI: 10.1039/C9LC00796B, CommunicationHyerin Kim, Kyu Hyoung Lee, Sung Il Han, Dongho Lee, Seok Chung, Dohwan Lee, Jeong Hoon LeeAn origami-paper-based device was developed for effective preconcentration and isolation of microvesicles/exosomes by ion concentration polarization.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Activate capture and digital counting (AC + DC) assay for protein biomarker detection integrated with a self-powered microfluidic cartridge
    by Congnyu Che on October 16, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3943-3953DOI: 10.1039/C9LC00728H, PaperCongnyu Che, Nantao Li, Kenneth D. Long, Miguel Ángel Aguirre, Taylor D. Canady, Qinglan Huang, Utkan Demirci, Brian T. CunninghamWe demonstrate a rapid and ultrasensitive assay for protein quantification through the nanoparticle–photonic crystal coupling embedded in microfluidic cartridges.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Continuous synthesis of carbon dots with full spectrum fluorescence and the mechanism of their multiple color emission
    by Meng Shao on October 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3974-3978DOI: 10.1039/C9LC00683D, PaperMeng Shao, Qin Yu, Nan Jing, Yu Cheng, Dong Wang, Yun-Dong Wang, Jian-Hong XuContinuous synthesis of carbon dots with full-spectrum fluorescence and the mechanism of their multiple color emission and applications.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Wash-free non-spectroscopic optical immunoassay by controlling retroreflective microparticle movement in a microfluidic chip
    by Ka Ram Kim on October 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3931-3942DOI: 10.1039/C9LC00973F, PaperKa Ram Kim, Hyeong Jin Chun, Kyung Won Lee, Kwan Young Jeong, Jae-Ho Kim, Hyun C. YoonA wash-free nonspectroscopic optical immunoassay system by controlling retroreflective Janus microparticles movement in a microfluidic chip was developed to minimize random errors under the point-of-care testing environment.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Non-swelling hydrogel-based microfluidic chips
    by Chong Shen on September 16, 2019 at 11:00 pm

    Lab Chip, 2019, 19,3962-3973DOI: 10.1039/C9LC00564A, PaperChong Shen, Yingjun Li, Ying Wang, Qin MengWe use a non-swelling hydrogel to construct microfluidic chips and show that they could potentially be applicable for cell/tissue-related applications, performing much better than conventional PDMS or existing hydrogel based microfluidic chips.The content of this RSS Feed (c) The Royal Society of Chemistry

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  • Electrochemical activation of graphene sheets embedded carbon films for high sensitivity simultaneous determination of hydroquinone, catechol and resorcinol
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Liangliang Huang, Yuanyuan Cao, Dongfeng DiaoAbstractIn this study, the graphene sheets embedded carbon (GSEC) film was electrochemically activated in KOH solution for high sensitivity simultaneous determination of hydroquinone (HQ), catechol (CC) and resorcinol (RC). The electrochemical activation mechanism of GSEC films in alkaline solution was clarified. We found that the embedded graphene sheets were corroded during activation, resulting in the formation of more defective graphene edges and […]

  • Corrigendum to “Ordered mesoporous In-(TiO2/WO3) nanohybrid: An ultrasensitive n-butanol sensor” [Sens. Actuators B 239 (2017) 364–373]
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Ritu Malik, Vijay K. Tomer, Vandna Chaudhary, Manjeet S. Dahiya, S.P. Nehra, Pawan S. Rana, Surender Duhan

  • Novel application of attapulgite on high performance and low-cost humidity sensors
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Zaihua Duan, Qiuni Zhao, Si Wang, Zhen Yuan, Yajie Zhang, Xian Li, Yingwei Wu, Yadong Jiang, Huiling TaiAbstractAttapulgite, as a natural mineral with excellent physicochemical properties, abundant reserves, and low price, has been widely used in industry and agriculture. With the advancement of research, novel applications of attapulgite are still emerging. In this work, a low-cost humidity sensor based on attapulgite is firstly fabricated. The results show that the attapulgite humidity sensor […]

  • Tunable formation of nanostructured SiC/SiOC core-shell for selective detection of SO2
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): A. Gaiardo, B. Fabbri, A. Giberti, M. Valt, S. Gherardi, V. Guidi, C. Malagù, P. Bellutti, G. Pepponi, D. Casotti, G. Cruciani, G. Zonta, N. Landini, M. Barozzi, S. Morandi, L. Vanzetti, R. Canteri, M. Della Ciana, A. Migliori, E. DemenevAbstractSilicon carbide is a well-known material with high thermal, mechanical and chemical stability. These properties have allowed, over time, its wide use as an inert material to be employed as a substrate or support in different applications. In this […]

  • A dense diffusion barrier limiting current oxygen sensor for detecting full concentration range
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Xuejiao Sun, Fangmeng Liu, Caileng Wang, Xinxin Liu, Juan Jian, Decheng Zeng, Liujun Liu, Hongming Yuan, Geyu LuAbstractAlthough the limiting current-type oxygen sensors based on dense diffusion barriers have been developed for detecting oxygen concentration in harsh exhaust environments, their oxygen concentration measuring range is far below that of the sensors based on porous diffusion barriers, which can be improved through using electrochemically stable mixed oxide-ion/electron conductor. […]

  • MoS2-enhanced epoxy-based plasmonic fiber-optic sensor for selective and sensitive detection of methanol
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Bobo Du, Yinlan Ruan, Thai-Thao Ly, Peipei Jia, Quantao Sun, Qingliang Feng, Dexing Yang, Heike Ebendorff-HeidepriemAbstractPlasmonic nanostructures have found widespread applications in nanophotonics, photochemistry and optoelectronics, and chemical sensing is one of their most vibrant applications. However, it still remains open to achieve selective detections with plasmonic nanostructures, especially, at room temperature. Polymers have been attractive as vapor sensitive materials as their […]

  • Wafer-scale few-layer graphene growth on Cu/Ni films for gas sensing applications
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Geetanjali Deokar, Juan Casanova-Cháfer, Nitul S. Rajput, Cyril Aubry, Eduard Llobet, Mustapha Jouiad, Pedro M.F.J. CostaAbstractPristine, few-layer graphene (FLG)/Si nanopillar assemblies are introduced as gas sensitive chemiresistors showing unprecedented sensitivity towards NO2 when operated at room temperature (25 °C) and in humid air. To achieve this, we first developed wafer-scale (∼50 cm2) FLG growth using sub-micrometer thick films of thermally evaporated Cu/Ni on a SiO2/Si […]

  • WO3 processed by direct laser interference patterning for NO2 detection
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): L. Parellada-Monreal, S. Gherardi, G. Zonta, C. Malagù, D. Casotti, G. Cruciani, V. Guidi, M. Martínez-Calderón, I. Castro-Hurtado, D. Gamarra, J. Lozano, L. Presmanes, G.G. MandayoAbstractIn this paper two kind of sensors based on WO3 sputtered by magnetron sputtering and annealed at 600 °C have been studied. The first kind was processed by two-dimensional direct laser interfering patterning (DLIP) and the second one without any additional treatment. Morphological […]

  • Room temperature detection and modelling of sub-ppm NO2 by low-cost nanoporous NiO film
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Mario Urso, Salvatore Gianluca Leonardi, Giovanni Neri, Salvatore Petralia, Sabrina Conoci, Francesco Priolo, Salvo MirabellaAbstractNiO-based NO2 sensors operating at room temperature are attracting great attentions due to their promising energy and cost saving performances. However, only a few reports showed high sensitivity and selectivity in the sub-ppm concentration range and low limit of detection (LoD). In this work, we designed and fabricated by a low-cost chemical bath deposition (CBD) […]

  • UV-activated ultrasensitive and fast reversible ppb NO2 sensing based on ZnO nanorod modified by constructing interfacial electric field with In2O3 nanoparticles
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Hongtao Wang, Linsheng Zhou, Yueying Liu, Fengmin Liu, Xishuang Liang, Fangmeng Liu, Yuan Gao, Xu Yan, Geyu LuAbstractThe poor recovery characteristic of NO2 sensors operated at room temperature is always a challenge to solve. In order to realize the combination of ultra-high response and fast response and recovery speed, heterogeneous interfacial electric fields are constructed by loading In2O3 nanoparticles on ZnO nanorods, which possess fast charge transfer ability, to improve the separation […]

  • Gas sensing of ordered and disordered structure SiO2 and their adsorption behavior based on Quartz Crystal Microbalance
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Juan Xie, Lei Zhang, Haiyang Xing, Penghui Bai, Biao Liu, Chenjie Wang, Kai Lei, Hu Wang, Shuo Peng, Shuang YangAbstractOrdered and disordered structure SiO2 were fabricated on quartz crystal microbalance (QCM) chips by two different self-assembly methods. Due to the special hexagonal alignment, ordered structure SiO2 exhibits good gas adsorption property to volatile organic compounds (VOCs) and small-molecule gases. Replacing model and Filling model were employed to explain the sensing mechanism […]

  • Detection of hexanal and 1-octen-3-ol in refrigerated grass carp fillets using a QCM gas sensor based on hydrophobic Cu(I)-Cys nanocomposite
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Wei Chen, Zhenhe Wang, Shuang Gu, Jun Wang, Yongwei Wang, Zhenbo WeiAbstractHexanal and 1-octen-3-ol have been identified previously as freshness indicators of refrigerated (4°C) grass carp fillets and increase from 0 day to 4 days. Thus, a novel quartz crystal microbalance (QCM) gas sensor was fabricated for hexanal and -1-octen-3-ol detection at room temperature with a hydrophobic cysteine sensitized Cu2O (Cu(I)-Cys) nanocomposite as the sensing layer. The QCM gas sensor coated with […]

  • Researching the crystal phase effect on gas sensing performance in In2O3 nanofibers
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Jing Cao, Ningrui Zhang, Shuangming Wang, Cong Chen, Haiming ZhangAbstractPhase structure, specific surface area and composition have great influence on the gas sensing performance, however the dominant factor is still unknown. In this study, In2O3 nanofiber (NF) and In2O3 flower-like nanofibers (FNF) with different phase structures, specific surface areas and morphologies are investigated to obtain in-depth understanding of how different factors alters gas sensing performances. In2O3 NF exhibits […]

  • In situ, portable and robust laser sensor for simultaneous measurement of ammonia, water vapor and temperature in denitrification processes of coal fired power plants
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Jinyi Li, Chenge Zhang, Yingying Wei, Zhenhui Du, Fushuang Sun, Yue Ji, Xiaotao Yang, Chang LiuAbstractSimultaneous measurement of the ammonia, flue gas temperature and water vapor concentration in denitrification (deNOx) processes is of great importance for improving the deNOx efficiency of coal-fired power plants (CFPPs) and maximizing energy conservation and emission reduction. A portable, robust, low-cost and low-power laser sensor was developed based on wavelength modulation spectroscopy […]

  • Lanthanide ions as sensor elements based sensor array for colorimetric identification of antioxidants
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Chi Zhang, Xin Li, Wei Wei, Zhengbo ChenAbstractA colorimetric sensor array consisting of three lanthanide ions (Eu3+, La3+, and Sm3+) as sensor elements and Eriochrome Black T (EBT) as signal readout was designed. In the presence of lanthanide ions, EBT and lanthanide ions form binary complexes, producing a color change from blue to pink. Upon the addition of antioxidants, the sensor array exhibits cross-reactive responses to antioxidants, the varying color and absorbance changes from the […]

  • Smartphone based platform for ratiometric fluorometric and colorimetric determination H2O2 and glucose
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Tao Liu, Shuxin Zhang, Wei Liu, Shun Zhao, Zhiwei Lu, Yanying Wang, Guangtu Wang, Ping Zou, Xianxiang Wang, Qingbiao Zhao, Hanbing RaoAbstractIn this work, a new strategy for ratiometric fluorescent and colorimetric determination of H2O2 and glucose is proposed. The sensing system involves catalytic oxidation reaction of glucose oxidase (GOx) with glucose to generate H2O2. Under the catalysis of Fe2+, the 580 nm emission of carbon dots (C-dots) upon 365 nm excitation is reduced by […]

  • Paper-based smartphone chemosensor for reflectometric on-site total polyphenols quantification in olive oil
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): D. Calabria, M. Mirasoli, M. Guardigli, P. Simoni, M. Zangheri, P. Severi, C. Caliceti, A. RodaAbstractHigh polyphenols levels are one of the main quality characters of Extra Virgin Olive Oil (EVOO), leading to high antioxidant activity and contributing to the EVOO health beneficial effects. Analytical methods for the rapid assessment of EVOO polyphenols content, possibly directly at the place of production or distribution, are therefore important for the commercial enhancement of this product. […]

  • SNR-enhanced temperature-insensitive microfiber humidity sensor based on upconversion nanoparticles and cellulose liquid crystal coating
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Siqi Hu, Shengnan Wu, Chenxi Li, Runze Chen, Erik Forsberg, Sailing HeAbstractCombining upconversion nanoparticles (UCNPs) and cellulose liquid crystal (CLC) film, a microfiber relative humidity (RH) sensor with enhanced signal-to-noise ratio (SNR) is proposed. The sensor head consist of a microfiber successively coated with a UCNP fluorescent layer and a hydrophilic CLC film layer. The UCNP fluorescence spectra is located in the photonic band gap of the CLC film, resulting in mirrorless low […]

  • The effect of methyl group functionality on the host-guest interaction and sensor behavior in metal-organic frameworks
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Somayeh Tarasi, Alireza Azhdari Tehrani, Ali MorsaliAbstractThe strategy of MOFs functionalization by modifying ligands is a powerful platform among other ongoing researchs which is creating high-performance MOFs. Ligands modification through the addition of support groups (in helping of host–guest main interaction sites) has a key role in the increasing of host molecule adsorption capacity. To investigate this issue we synthesized two structures TMU-59 and TMU-6(RL1) and studied the effect […]

  • A novel fluorescent protein chromophore analogue to simultaneously probe lysosome viscosity and β-amyloid fibrils
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Han Sun, Hua-xiang Leng, Jin-sheng Liu, Gaurab Roy, Jin-wu Yan, Lei ZhangAbstractAlzheimer's disease (AD) is an incurable neurodegenerative disease. Better diagnosis of AD is extremely important for therapeutic interventions. The amyloid cascade hypothesis and its revised version identify insoluble β-amyloid deposition as a good diagnostic biomarker for AD. We hypothesize that lysosomal viscosity may also act as an auxiliary biomarker for AD based on literature research. Herein, we have […]

  • Discriminating Cys from GSH/H2S in vitro and in vivo with a NIR fluorescent probe
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Linlin Zhu, Tiange Zhang, Yanyan Ma, Weiying LinAbstractBiothiols play a prominent role in physiological and pathological processes as reactive sulfur species (RSS), which are closely related to the pathways of metabolism of living animals. By reason of their similar chemical structure and properties, it is challenging to distinguish biological mercaptans from each other in living systems. Herein, a NIR probe (NN) for effectively distinguishing cysteine (Cys) from glutathione (GSH)/hydrogen […]

  • Stretchable energy storage E-skin supercapacitors and body movement sensors
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Jian Wang, Hengyi Lou, Junjing Meng, Zhiqin Peng, Bing Wang, Junmin WanAbstractElectronic skin (e-skin) with natural stimuli is a key factor in prosthetics, robotics, and wearable electronics. At present, most traditional stretchable e-skins fabricated by predesigning complex 3D structures are unsuitable in commercial applications. Energy storage devices with stretchable and arbitrary shapes can widely adapt to wearable electronics. Stretchable supercapacitors and sensors have been used as the […]

  • Non-covalent modification of glassy carbon electrode with isoorientin and application to alpha-fetoprotein detection by fabricating an immunosensor
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Peiying Shi, Rongfang Xie, Panpan Wang, Yun Lei, Bing Chen, Shaoguang Li, Youjia Wu, Xinhua Lin, Hong YaoAbstractIn this study, the glassy carbon electrode (GCE) surface substructure and geometry were originally modeled by first principles density functional theory (DFT) methods with a simple basis set AFPD/3−21 G. Isoorientin was then used as a model to explore the adsorbates bonding effect on GCE surface with experimental and computational methods. It was confirmed that the modification […]

  • Effect of Sn doping and annealing on the morphology, structural, optical, and electrical properties of 3D (micro/nano) V2O5 sphere for high sensitivity pH-EGFET sensor
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Lary H. Slewa, Tariq A. Abbas, Naser M. AhmedAbstractSn-doped 3D (micro/nano) V2O5 was synthesized on macro porous silicon (PSi) by solvothermal method for pH-EGFET sensor. Effect of Sn-dopant concentration and thermal annealing on the structure, morphology, optical, and electrical properties of the synthesized samples was analyzed. XRD analysis using Rietveld refinements confirmed decreasing in the crystalline size and lattice expansion of Sn-doped V2O5 with the doping concentration. FESEM […]

  • Construction of the direct Z-scheme CdTe/APTES-WO3 heterostructure by interface engineering for cathodic “signal-off” photoelectrochemical aptasensing of streptomycin at sub-nanomole level
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Dong Liu, Xixi Xu, Xiuli Shen, Lijun Luo, Libo Li, Xiaohong Yan, Tianyan YouAbstractThe newly-emerging direct Z-scheme heterostructures have been extensively studied as photocatalysts; however, their photoelectrochemical (PEC) aptasensing applications are still in infancy. In this work, we constructed a novel direct Z-scheme heterostructure with CdTe quantum dots (QDs) and WO3 nanosheets via interface engineering for PEC aptasensing of streptomycin (STR). To fabricate the solid-solid interface […]

  • An ammonia sensor composed of polypyrrole synthesized on reduced graphene oxide by electropolymerization
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Xiaohui Tang, Jean-Pierre Raskin, Nadzeya Kryvutsa, Sophie Hermans, Oleksandr Slobodian, Alexei N. Nazarov, Marc DebliquyAbstractWe report an ammonia (NH3) sensor in which a ultrathin polypyrrole (PPy) layer is synthesized on reduced graphene oxide (rGO) by electropolymerization. The PPy/rGO composite is characterized by scanning electron microscopy, secondary ion mass spectrometry, Raman spectroscopy, and X-ray photoelectron spectroscopy. The sensor exhibits an excellent performance in the […]

  • Functional fullerene-molybdenum disulfide fabricated electrochemical DNA biosensor for Sul1 detection using enzyme-assisted target recycling and a new signal marker for cascade amplification
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Huan You, Zhaode Mu, Min Zhao, Jing Zhou, Yonghua Yuan, Lijuan BaiAbstractThis work describes a DNA biosensor for sensitive detection of the specific Sul1 gene of Salmonella typhimurium. First of all, polyamidoamine (PAMAM) functionalized fullerene (C60) and molybdenum disulfide (MoS2) nanohybrid is synthesized and employed as sensing platform. Secondly, MoS2 doped polyaniline (PANI) nanocomposite is designed as redox nanoprobe to enhance electrochemical signal. Moreover, exonuclease III (exo […]

  • Ordinary microfluidic electrodes combined with bulk nanoprobe produce multidimensional electric double-layer capacitances towards metal ion recognition
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Giulia S. da Silva, Luiza P. de Oliveira, Gabriel F. Costa, Gabriela F. Giordano, Caroline Y.N. Nicoliche, Alexandre A. da Silva, Latif U. Khan, Gabriela H. da Silva, Angelo L. Gobbi, José V. Silveira, Antonio G. Souza Filho, Gabriel R. Schleder, Adalberto Fazzio, Diego S.T. Martinez, Renato S. LimaAbstractWhile multidimensional sensors are powerful platforms towards multitarget analyses, the successive synthesis/fabrication of multiple probes and measurements to each one of these units […]

  • DNA-linked CdSe QDs/AGQDs “Z-scheme” system: Ultrasensitive and highly selective photoelectrochemical sensing platform with negative background signal
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Leixia Meng, Ke Xiao, Xiaohua Zhang, Cuicui Du, Jinhua ChenAbstractDepended on the target-induced formation of a DNA-linked CdSe quantum dots/amino-functionalized graphene quantum dots (denoted as CdSe QDs/AGQDs) “Z-scheme” system, an ultrasensitive and highly selective PEC sensing platform has been constructed for DNA assay. Firstly, the indium tin oxide (ITO) electrode was modified with the poly(diallyldimethylammonium chloride) (PDDA)-decorated reduced graphene oxide (PDDA-rGO) to […]

  • Ultrasensitive non-enzymatic pesticide electrochemical sensor based on HKUST-1-derived copper oxide @ mesoporous carbon composite
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Chunmeng Gu, Qian Wang, Li Zhang, Pingping Yang, Yixi Xie, Junjie FeiAbstractElectrochemical sensors for monitoring pesticides have attracted great interest recently. Herein, we report a novel strategy to fabricate an ultrasensitive non-enzymatic pesticide sensor based on glass carbon electrode (GCE) modified by copper oxide @ mesoporous carbon (CuOx@mC) composite derived from directly pyrolysing metal–organic framework HKUST-1. The formation of CuOx@mC composite was confirmed by multiple […]

  • Controlling inter-sheet-distance in reduced graphene oxide electrodes for highly sensitive electrochemical impedimetric sensing of myoglobin
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Seong Soo Yoo, So Young Kim, Kwang Su Kim, Sunghwan Hong, Min Jun Oh, Myeong Gyun Nam, Woo-Jae Kim, Juhyun Park, Chan-Hwa Chung, Woo-Seok Choe, Pil J. YooAbstractIn order to improve the sensitivity of electrochemical impedance spectroscopy (EIS)-based biosensors, a number of structuring strategies to promote enlarging the electroactive surface area have been recently proposed. However, these approaches have not been applicable to graphene-based electrodes especially due to their ultrathin film […]

  • Synthesis of 0D to 3D hybrid-carbon nanomaterials carrying platinum(0) nanoparticles: Towards the electrocatalytic determination of methylparabens at ultra-trace levels
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Jose Muñoz, Ignacio Álvarez-Prada, Eric Lopez-Lopez, Lluís Escriche, Nuria Romero, Xavier Sala, Marta Mas-Torrent, Jordi García-AntónAbstractA generic synthetic methodology has been applied for functionalizing four conducting carbon nanoallotropes, such as 0D carbon nanohorns (CNHs), 1D carbon nanotubes (CNTs), 2D reduced graphene oxide (rGO) and 3D graphite (GP) with platinum(0) nanoparticles (Pt–NP), and exploited towards the electrocatalytic […]

  • Molybdenum disulfides nanoflowers anchoring iron-based metal organic framework: A synergetic catalyst with superior peroxidase-mimicking activity for biosensing
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Wenfei Dong, Guo Chen, Xue Hu, Xiaodan Zhang, Wenbing Shi, Zhifeng FuAbstractA novel nanostructure MoS2 nanoflowers anchoring iron(III)-based metal-organic framework MIL-101(Fe) [Fe3O(H2O)2Cl(O2C–C6H4−CO2)3], named MoS2-MIL-101(Fe), was prepared by growing MIL-101(Fe) crystals with as-prepared MoS2. Then, MoS2-MIL-101(Fe) was characterized through SEM, TEM, BET, XRD, DLS, and XPS. MoS2-MIL-101(Fe) possesses synergetic peroxidase-mimicking activity over individual MIL-101(Fe) and MoS2, […]

  • Synthesizing anode electrochemiluminescent self-catalyzed carbon dots-based nanocomposites and its application in sensitive ECL biosensor for microRNA detection
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Xia Zhong, Xue Li, Ying Zhuo, Yaqin Chai, Ruo YuanAbstractIn this work, a novel self-catalyzed carbon dots-based electrochemiluminescence (ECL) luminophore was prepared by loading the amino modified carbon dots onto the surface of AuNPs modified TiO2NPs (CDs-Au-PEI@TiO2) and applied in sensitive ECL biosensor for miRNA-21 detection. Significantly, the prepared CDs-Au-PEI@TiO2 nanocomposites exhibited strong initial ECL intensity for the acceleration of TiO2NPs towards to the electrochemical […]

  • Biocompatible electronic platform for monitoring protein-drug interactions with potential in future theranostics
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Sophia Selvarajan, Nagamalleswara Rao Alluri, Arunkumar Chandrasekhar, Sang-Jae KimAbstractSolid-state electronic devices based on biomolecules as current carrying elements have numerous applications from diagnostics to therapeutics. Casein micelle based solid-state device through metal-protein-metal electrical junctions designed for elucidating protein-drug interaction as well as proof-of-concept theranostics are the highlights of this proposed work. This biocompatible electronic platform has […]

  • Detection and discrimination of single nucleotide polymorphisms by exploiting metal ion-mediated DNA duplex
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Chanho Park, Yeongeun Yu, Haenglyun Jung, Kuewhan Jang, Sungsoo NaAbstractDetection of mutant DNA is necessary for early diagnosis of disease. In particular, detection of single nucleotide polymorphisms (SNPs) has become an important method for monitoring cancer and obtaining theragnostic information about it. SNPs are very difficult to detect selectively because of their similarity with wildtype DNA. In this paper, the specific binding between metal ion and DNA mismatch was used to achieve […]

  • Thi-Au-Fe3O4 confined in ZIF-8 nanoreactor as signal-amplifying tag for constructing high-efficiency electrochemical platform
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Yan Huang, Ruoqi Liang, Hua Yu, Shangjie An, Jing Han, Gang Xie, Sanping ChenAbstractHerein, we first present an effective strategy by the co-encapsulation of electrocatalyst (Fe3O4) and redox specie (thionine) in ZIF-8 called Thi-Au-Fe3O4@ZIF-8 that acted as signal tag for the ultrasensitive assay of α-fetoprotein (AFP). It is worth noting that the structural “confinement effect” of ZIF-8 provides microenvironments for Fe3O4 and thionine (Thi) within a certain spatial region, […]

  • 4-Dimensional observation ER-mitochondria interaction in living cells under nanoscopy by a stable pyridium salt as biosensor
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Fenfang Zhu, Zhenghui Yang, Fei Wang, Dandan Li, Hongzhi Cao, Yupeng Tian, Xiaohe TianAbstractIntracellular membrane-bounded organelles are physically associated and play critical roles in many physiological processes. However, real-time monitoring of their interaction at the nanoscale in three-dimension (xyz-t or 4D imaging) remains considerable difficulties due to limitations of the current super-resolution probe toolbox. Here, we developed a novel cell-permeable pyridium salt derivative […]

  • A regenerated nanotweezer-managed catalytic DNA circuit for cancer-related sensing
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Wei Li, Yushu Wu, Yifan Jin, Jingyi Wang, Haixia GaoAbstractIn this study, a regenerated nanotweezer-managed catalytic DNA circuit was constructed. A nanotweezer with two crossover motifs was assembled using 10 oligonucleotides, a toehold domain (TD), and a branch migration domain (BMD) as the two motifs of the nanotweezer. In the absence of a catalyst, the nanotweezer was opened, the TD and the BMD were separated with few catalytic activities. Upon catalyst addition, the set strand in the […]

  • Efficient formaldehyde sensor development based on Cu-codoped ZnO nanomaterial by an electrochemical approach
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Mohammed Muzibur RahmanAbstractAn aggregated copper codoped zinc oxide (CZO; CuO.ZnO) nanomaterial was synthesized to detect formaldehyde (HCHO) from aqueous solution via electrochemical reactions. The as-grown CZO nanostructures have a typical diameter of 140 ± 15 nm in size. From the spectroscopic and electrochemical studies it was revealed that the CZO nanomaterials exhibit completely different electrochemical and electro-catalytic properties from the constituents. In […]

  • Gaining insight into electrolyte solution effects on the electrochemomechanical behavior of electroactive PU/PPy nanofibers: Introducing a high-performance artificial muscle
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Seyed Vahid Ebadi, Dariush Semnani, Hossein Fashandi, Behzad Rezaei, Aref FakhraliAbstractThe unique properties of nanofibrous artificial muscles including high specific surface area, high porosity, and flexibility as well as similarity to natural muscle structures make them a promising option for use in advanced technologies. In this study, a polyurethane/polypyrrole (PU/PPy) nanofibrous bending artificial muscle was produced and contribution of important electrolyte specifications including […]

  • Ultra-thin free-floating carbon nanotube/gold nanoparticle hybrid film prepared with self-assembly protein of α-synuclein
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Jong Tak Lee, Junghee Lee, Yeji Kwon, Jin Young Kim, Yuxi Lin, Young-Ho Lee, Seung R. PaikAbstractFabrication of ultra-thin 2D film of carbon nanotubes (CNTs) is achieved by employing a self-assembly protein of α-synuclein (αS). Electron energy loss spectroscopy-transmission electron microscopy and circular dichroism spectroscopy analyses indicate that αS binds to the hydrophobic surface of CNT through its N-terminal region by forming α-helix. 1H-15N heteronuclear […]

  • A solid-phase direct contact bioassay using sulfur-oxidizing bacteria (SOB) to evaluate toxicity of soil contaminated with heavy metals
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Heonseop Eom, Ebenezer Ashun, Umair Ali Toor, Sang-Eun OhAbstractThe current study tested the employment of sulfur-oxidizing bacteria (SOB) in a direct contact bioassay to evaluate toxicity of soil contaminated with heavy metals. SOB were directly exposed to soil spiked with arsenic, nickel, hexavalent chromium, zinc, mercury, copper, lead, or cadmium for 12 h in a kit-type bioassay. Oxygen consumption by SOB was used as the end-point for toxicity assessment. The results demonstrate that […]

  • Highly sensitive and stable analysis of trace arsenic(III) and mercury(II) in water by Low-pulse-energy (15 mJ) laser-induced breakdown spectroscopy assisted by active controllable spark discharge and electrochemical enrichment
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Min Jiang, Ming-Jun Ma, Meng Yang, Li Fang, Yi-Xiang Li, Nan-Jing Zhao, Xing-Jiu HuangAbstractLaser-induced breakdown spectroscopy (LIBS) has emerged as promising technology in view of its unique advantages and application in analysis of environmental samples. However, such a method encounters significant challenges in detecting arsenic and mercury, which are prone to volatilization at high pulse energy. Herein, a new approach, low-pulse-energy LIBS supported by active controllable spark […]

  • Size-controllable Fe-N/C single-atom nanozyme with exceptional oxidase-like activity for sensitive detection of alkaline phosphatase
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Qiumeng Chen, Siqi Li, Yuan Liu, Xiaodan Zhang, Yue Tang, Hongxiang Chai, Yuming HuangAbstractNanozymes become currently a frontier of chemical research. However, exploiting a novel nanozyme with high activity, good stability and reproducibility is challenging. Here, size-controllable Fe-N/C nanozymes containing exclusive single Fe atoms coordinated Fe-Nx sites were succesfully prepared through a facile pyrolysis of size controllable Fe-Zn ZIFs precursors. The Fe-N/C nanozymes exhibit exceptional […]

  • MoOx quantum dots with peroxidase-like activity on microfluidic paper-based analytical device for rapid colorimetric detection of H2O2 released from PC12 cells
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Meng-Meng Liu, Shan-Hong Li, Dan-Dan Huang, Zhi-Wei Xu, Ya-Wei Wu, Yun Lei, Ai-Lin LiuAbstractDiagnostic assays made of microfluidic paper-based analytical devices have become the focus of considerable attention in developing countries because of simplicity, low cost, user friendliness, and no requirement for complex equipment, which is suitable to point-of-care testing. Considering the intrinsic shortcomings of nature enzyme, synthesis of artificial peroxidase mimics possessing improved […]

  • PEDOT coating enhanced electromechanical performances and prolonged stable working time of IPMC actuator
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Dongjie Guo, Long Wang, Xinjie Wang, Yanan Xiao, Caidong Wang, Lumin Chen, Yonghui DingAbstractCurrent ionic exchange polymer metal composite (IPMC) has always been associated with short stable working time due to the presence of severely electrode fatigue and water loss, which limits its wide-spread applications. To address this problem, a facile and effective strategy has been proposed to repair the IPMC by electrografting a conductive, flexible polymer of Poly(ethylenedioxythiophene) (PEDOT) […]

  • High-throughput generation of a concentration gradient on open arrays by serial and parallel dilution for drug testing and screening
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Xinlian Chen, Bing Ji, Xinghua Gao, Mengying Zhang, Chang Xue, Bingpu Zhou, Jinbo WuAbstractIn this study, we successively and parallelly slide a solvent strip on a polydimethylsiloxane microwell array to dilute the solution within the microwells. A total of 60 concentration gradients were generated one by one along the sliding direction within minutes while simultaneously forming 60 microwells with the same concentration perpendicular to the sliding direction. Using theoretical calculations, […]

  • Portable liquid chromatography for point-of-care testing of glycated haemoglobin
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Ding Li, Haiyan Chen, Shuang Ren, Yanfang Zhang, Yang Yang, Honglong ChangAbstractLiquid chromatography (LC) coupled with absorption detection plays an important role in the analytical field. However, the miniaturisation of the whole system is still a challenging problem. Here we developed a compact and lightweight LC system with overall size of 20 cm × 16 cm × 16 cm and weight of 1.8 kg for the fast and accurate measurement of glycated […]

  • Insight into highly selective dimethyl trisulfide detection based on WO3 nanorod bundles with exposed (002) facets
    on December 13, 2019 at 4:35 am

    Publication date: 15 February 2020Source: Sensors and Actuators B: Chemical, Volume 305Author(s): Xiafen Hu, Xiaoxia Wang, Tingting Zhou, Xiangfeng Chu, Changsheng Xie, Dawen ZengAbstractMetal oxide semiconductors (MOS)-based gas sensor for food-borne pathogens detecting via special biological metabolites, require high selectivity due to the possible sensing interference, which is an issue still to be resolved [[1], [2], [3], [4]]. In this work, WO3 nanorod bundles were synthesized via a hydrothermal method, and its rapid response, high sensitivity and selectivity are demonstrated for […]

Microsystems & Nanoengineering - nature.com technology Microsystems & Nanoengineering is an international open access journal, publishing original articles and reviews covering all aspects of microsystems and nanoengineering from fundamental to applied research.

  • Displacement Talbot lithography for nano-engineering of III-nitride materials
    by Pierre-Marie Coulon on December 2, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 02 December 2019; doi:10.1038/s41378-019-0101-2Displacement Talbot lithography enables the low-cost fabrication of a range of nanostructures from III-nitride materials. III-nitride semiconductors provide interesting and useful optical properties when formed into nanostructures, with numerous device applications. However, several key performance parameters are sometimes limited due to crystal defects, or for devices larger than the nanoscale. Now, an international group led by Philip Shields from University of Bath, UK, apply Displacement […]

  • Quantitative phase imaging of erythrocytes under microfluidic constriction in a high refractive index medium reveals water content changes
    by Han Sang Park on December 2, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 02 December 2019; doi:10.1038/s41378-019-0113-yA team at Duke University in the United States led by Han Sang Park has developed a novel approach to investigate the deformability of cells. The technique uses quantitative phase microscopy to measure optical volume as cells are squeezed through a constriction. The team used this approach to study changes in red blood cells that had been stored for up to 29 days. The older cells had a larger volume before constriction, and their volume changed less when they were squeezed. The increased […]

  • Kirigami-inspired multiscale patterning of metallic structures via predefined nanotrench templates
    by Mengjie Zheng on December 2, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 02 December 2019; doi:10.1038/s41378-019-0100-3A centuries-old papercrafting technique has inspired an approach for the reproducible manufacture of metal structures with precisely defined macro- and nanoscale features. Many electronic devices incorporate such elements, but current production processes struggle with the ability to accurately sculpt both millimeter- and nanometer-sized design elements. Researchers led by Yihui Zhang of Tsinghua University and Huigao Duan of Hunan University tackled this challenge with a 21st century version […]

  • Direct growth of ZnO nanowires on civil engineering materials: smart materials for supported photodegradation
    by Marie Le Pivert on November 18, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 18 November 2019; doi:10.1038/s41378-019-0102-1An easy, low-cost method has been developed for successfully synthesizing zinc oxide (ZnO) nanostructures onto commercially available materials for environmentally safe use in civil engineering. Photocatalysis is the process whereby light accelerates a chemical reaction, and it holds promise as a means of tackling pollution caused by civil engineering materials. Previous efforts to produce such materials by incorporating ZnO and titanium oxide (TiO2) nanoparticles for photocatalysis have […]

  • Glassy carbon microelectrodes minimize induced voltages, mechanical vibrations, and artifacts in magnetic resonance imaging
    by Surabhi Nimbalkar on November 18, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 18 November 2019; doi:10.1038/s41378-019-0106-xEvidence suggests that neural implants based on glassy carbon are safe during MRI scans and do not distort scan images. Glassy carbon (GC) is becoming a preferential material in biosensors such as implants for brain wave recording or deep brain stimulation. To be useful, new neural implants should be maintained compatible with MRI scanning, as MRI has previously been known to induce vibration and heating of implants, induce an electrical current in the implant, and distort MR images. Sam […]

  • Microplasma direct writing for site-selective surface functionalization of carbon microelectrodes
    by Aung Thiha on November 18, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 18 November 2019; doi:10.1038/s41378-019-0103-0A new approach for controlled ‘writing’ with a microscale plasma stream enables precise and efficient chemical modification of three-dimensional carbon electrodes. Such materials are highly desirable for diverse microelectronics applications, but conventional plasma-based techniques for targeted modification are relatively labor-intensive. Fatimah Ibrahim and colleagues at the University of Malaya have devised a novel strategy in which a controllable conductive microelectrode is […]