Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00711D, PaperMingxin Xu, Peter V. S. Lee, David J. CollinsWe demonstrate microfluidic acoustic sawtooth-like metasurfaces that create steerable acoustofluidic fields for microscale patterning and separation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2022, Accepted ManuscriptDOI: 10.1039/D1LC00880C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Andreas Link, John S McGrath, Mustafa Zaimagaoglu, Thomas FrankeWe demonstrate the use of an acoustic device to actively encapsulate single red blood cells into individual droplets in a T-junction. We compare the active encapsulation with the passive encapsulation...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2022, Advance ArticleDOI: 10.1039/D1LC00689D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Johannes Dornhof, Jochen Kieninger, Harshini Muralidharan, Jochen Maurer, Gerald A. Urban, Andreas WeltinAn organ-on-chip platform equipped with microsensors for long-term microfluidic cultivation and metabolic monitoring (O2, Glu, Lac) of 3D tumour organoid cultures grown from patient-derived single cancer stem cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this […]

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC01006A, CommunicationErik S. Lamoureux, Emel Islamzada, Matthew V.J. Wiens, Kerryn Matthews, Simon P. Duffy, Hongshen MaRed blood cells (RBCs) must be highly deformable to transit through the microvasculature to deliver oxygen to tissues. The loss of RBC deformability resulting from pathology, natural aging, or storage...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00889G, PaperOzgun Civelekoglu, Ruxiu Liu, Can Firat Usanmaz, Chia-Heng Chu, Mert Boya, Tevhide Ozkaya-Ahmadov, A K M Arifuzzman, Ningquan Wang, A. Fatih SariogluMembrane antigens are phenotypic signatures of cells used for distinguishing various subpopulations and therefore, are of great interest for diagnosis diseases and monitoring of patient in hematology and oncology. Existing...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00605C, PaperMax A Winkelman, Diana Y Kim, Shravani Kakarla, Alexander Grath, Nathaniel Silvia, Guohao DaiThe convective transport of fluid through tissue is an important factor in human biology, including the development of brain microvascular networks (MVNs) with a functional blood-brain barrier (BBB). Engineering a...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00846C, PaperHsiu-Yang Tseng, Chiu-Jen Chen, Zong-Lin Wu, Yong-Ming Ye, Guo-Zhen HuangCell-membrane permeability to water (Lp) and cryoprotective agents (Ps) of a cell type is a crucial cellular information for achieving optimal cryopreservation in the biobanking industry. In this work, a...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00669J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Hossein Eslami Amirabadi, Joanne Donkers, Esmée Wierenga, Bastiaan Ingenhut, Lisanne Pieters, Lianne Stevens, Tim Donkers, Joost Westerhout, Rosalinde Masereeuw, Ivana Bobeldijk, Irene Nooijen, Evita van der SteegThe majority of intestinal in vitro screening models use cell lines that do not reflect the complexity of the human intestinal tract and hence often fail to accurately predict intestinal...The […]

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00879J, PaperFatemeh Haghayegh, Razieh Salahandish, Azam Zare, Mahmood Khalghollah, Amir Sanati-NezhadOptimized self-contained microfluidic platform allows for single-step detection of proteins, through passive delivery of the dry-stored reagents required for immunosensing. Novel autonomous performance of the platform advances the point-of-care utilization of electrochemical protein sensing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00740H, PaperLiang Huang, Xu Zhang, Yongxiang Feng, Fei Liang, Wenhui WangHigh content screening (HCS) plays an important role in biological applications, and drug development. Existing techniques fail to simultaneously meet multiple needs of throughput, efficiency in sample and chemical consumption,...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00451D, PaperSina Nejati, Jiangshan Wang, Ulisses Heredia-Rivera, Sotoudeh Sedaghat, Ian Woodhouse, Jay S. Johnson, Mohit Verma, Rahim RahimiA non-invasive sampling capsule is introduced to site-selectively collect calprotectin biomarker from the small intestine. This approach can be accompanied with the fecal calprotectin assay to diagnose IBD and differentiate its types (CD and UC).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00801C, PaperHyeono Nam, Hyung Jin Sung, Jinsoo Park, Jessie S. JeonTSAWs quickly form a tumor spheroid for a drug screening platform.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00810B, PaperDeepshika Gilbile, Megan L. Shelby, Artem Y. Lyubimov, Jennifer L. Wierman, Diana C. F. Monteiro, Aina E. Cohen, Silvia Russi, Matthew A. Coleman, Matthias Frank, Tonya L. KuhlThis work presents our development of versatile, inexpensive, and robust polymer microfluidic chips for routine and reliable room temperature serial X-ray crystallography measurements.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00720C, PaperAmirali Selahi, Teshan Fernando, Sanjukta Chakraborty, Mariappan Muthuchamy, David C. Zawieja, Abhishek JainA microphysiological system of a lymphatic vessel is presented recapitulating crosstalk of lymphatic endothelial and muscle cells co-cultured cylindrically using a unique gravitational lumen patterning technique.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00665G, Critical ReviewKuangwen Hsieh, Johan H. Melendez, Charlotte A Gaydos, Jeff Tza-Huei WangThe rate of sexually transmitted infections (STIs), including the four major curable STIs – chlamydia, gonorrhea, trichomoniasis and, syphilis – continue to increase globally, causing medical cost burden and morbidity...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00789K, PaperNoa Renous, Mark Dan Kiri, Ronny Aharon Barnea, Rossana Rauti, Yael Leichtamnn-Bardoogo , Ben MaozTransepithelial/transendothelial electrical resistance (TEER) is a label-free assay that is commonly used to assess tissue barrier integrity. TEER measurement systems have been embedded in Organ-on-a-Chip devices to provide live readouts...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00886B, PaperKaifeng Zhao, Yaoping Liu, Hua Wang, Yanling Song, Xiao-Feng Chen, Chen Huang, Qi Niu, Jiao Cao, Xin Chen, Chaoyong James Yang, Wei Wang, Lingling WuRapid, efficient, and selective separation of tumor cells from complex body fluids is urgently needed for clinical application of tumor-cell-based liquid biopsy. Herein, a size-selective affinity filtration system, named Selective,...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00600B, PaperRegan P. Moore, Ellen C. O'Shaughnessy, Yu Shi, Ana T. Nogueira, Katelyn M. Heath, Klaus M. Hahn, Wesley R. LegantFEP-based microfluidics enable diverse applications in light sheet microscopy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00755F, PaperYongxiang Feng, Zhen Cheng, Huichao Chai, Weihua He, Liang Huang, Wenhui WangWe propose to employ NN-enhanced IFC to achieve both real-time single-cell intrinsic characterization and intrinsic metric-based cell classification at high throughput.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00869B, Critical ReviewHAOTIAN CHA, Hedieh Fallahi, Yuchen Dai, Dan Yuan, Hongjie An, Nam-Trung Nguyen, Jun ZhangMultiphysics microfluidics, which combines multiple functional physics in a microfluidic platform, is an emerging research area that attracts increasing interest in diverse biomedical applications. Multiphysics microfluidics is expected to overcome...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00807B, PaperChenchen Zhou, Shuaishuai Liang, Yongjian Li, Haosheng Chen, Jiang Li3D microparticles have promising applications in self-assembly, biomedical engineering, mechanical engineering, etc. The shape of microparticles plays a significant role in their functionalities. Although numerous investigations have been conducted to...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Accepted ManuscriptDOI: 10.1039/D1LC00721A, PaperTao Tang, Xun Liu, yapeng Yuan, Ryota Kiya, Yigang Shen, TIANLONG ZHANG, Kengo Suzuki, Ming Li, Yo Tanaka, Yoichiroh Hosokawa, Yalikun YaxiaerIntracellular components (including organelles and biomolecules) at the submicron level are typically analyzed in situ by special preparation or expensive setups. Here, a label-free and cost-effective approach of screening microalgal...The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00813G, CommunicationDavid Pérez-Guaita, Zack Richardson, Guillermo Quintás, Julia Kuligowski, Diana E. Bedolla, Hugh J. Byrne, Bayden WoodThe 3d printed system presented integrates isolation, preconcentration, and measurement of infrared spectra of cells from biofluids, enabling enhanced specific infrared spectra of cells down to 10 cells μL−1.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00829C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Daigo Natsuhara, Ryogo Saito, Hiroka Aonuma, Tatsuya Sakurai, Shunya Okamoto, Moeto Nagai, Hirotaka Kanuka, Takayuki ShibataWe developed a microfluidic flow control theory to provide design guidelines for multiplexed genetic diagnostic devices capable of sequential dispensing of samples into an array of reaction microchambers in a single operation.To cite this article before page numbers are assigned, use the DOI form of […]

Lab Chip, 2021, 21,4517-4548DOI: 10.1039/D1LC00627D, Critical ReviewHarshit Harpaldas, Siddarth Arumugam, Chelsey Campillo Rodriguez, Bhoomika Ajay Kumar, Vivian Shi, Samuel K. SiaThis article reviews the rapid and unprecedented development, scaleup and deployment of POC devices in response to the COVID-19 pandemic and its implications for the future of diagnostics and digital health.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00915J, PaperSiyuan Wang, Gaozhe Cai, Hong Duan, Wuzhen Qi, Jianhan LinThis study developed a slidable centrifugal disc for automatic and multi-channel detection of Salmonella using FTA card for DNA extraction and RAA for DNA detection and verified it could detect 10 CFU mL−1 in chicken meat supernatant in 1 h.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00567G, PaperTahereh Khajvand, Peifeng Huang, Linmei Li, Mingxia Zhang, Fengjiao Zhu, Xing Xu, Mengjiao Huang, Chaoyong Yang, Yao Lu, Zhi ZhuMultiplexed single-cell protein secretion profiling has been realized on an integrated microfluidic platform. The secreted proteins from each individual cell are captured by specific pre-patterned antibody sites and detected by off-chip ELISA.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00744K, PaperBrian J. O'Grady, Michael D. Geuy, Hyosung Kim, Kylie M. Balotin, Everett R. Allchin, David C. Florian, Neelansh N. Bute, Taylor E. Scott, Gregory B. Lowen, Colin M. Fricker, Matthew L. Fitzgerald, Scott A. Guelcher, John P. Wikswo, Leon M. Bellan, Ethan S. LippmannParylene deposition on 3D prints creates biocompatible microdevices and facilitates fabrication of master molds.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4685-4695DOI: 10.1039/D1LC00565K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jessi Carolina Ardila Riveros, Anna Karolina Blöchinger, Scott Atwell, Michel Moussus, Nina Compera, Omid Rajabnia, Tihomir Georgiev, Heiko Lickert, Matthias MeierHere we developed an automated mLSI chip platform with general analytical workflow for 3D stem cell cultures offers the optimization of in vitro generation of various cell types for cell replacement therapies.The content of this RSS Feed (c) The Royal […]

Lab Chip, 2021, 21,4716-4724DOI: 10.1039/D1LC00636C, PaperJiumei Hu, Liben Chen, Pengfei Zhang, Kuangwen Hsieh, Hui Li, Samuel Yang, Tza-Huei WangWe developed a facile PDMS-based, vacuum-assisted microfluidic device that can perform multi-step and multi-reagent digital assays.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4596-4607DOI: 10.1039/D1LC00614B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Rodrigo Ruz-Cuen, J. Martin de los Santos-Ramírez, Braulio Cardenas-Benitez, Cinthia J. Ramírez-Murillo, Abbi Miller, Kel Hakim, Blanca H. Lapizco-Encinas, Victor H. Perez-GonzalezTrapping voltage in 2D DC-iEK systems was significantly reduced (∼80 V) via a design optimization process primarily focused on E-field amplification.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00895A, PaperJiao Zhai, Caiwei Li, Haoran Li, Shuhong Yi, Ning Yang, Kai Miao, Chuxia Deng, Yanwei Jia, Pui-In Mak, Rui P. MartinsA digital microfluidic system with an innovative control structure and chip design to generate concentrations that span three to four orders of magnitude for single or multi-drug dispensing was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4608-4617DOI: 10.1039/D1LC00840D, PaperShupeng Ning, Shuchang Liu, Yunjie Xiao, Guanyu Zhang, Weiwei Cui, Mark ReedWe demonstrate a label-free, high-throughput cell separation method via a SSAW-based acoustofluidic device with a serpentine channel for clinical diagnosis and point-of-care analysis.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4557-4565DOI: 10.1039/D1LC00742D, PaperHye Jin Kim, Dongsung Park, Gyihyaon Yun, Hongrae Kim, Hyug-Gi Kim, Kyung Mi Lee, Il Ki Hong, Key-Chung Park, Jin San Lee, Kyo Seon HwangScreening of cerebral amyloid angiopathy and Alzheimer's disease by analyzing plasma amyloid-β using a highly sensitive dielectrophoretic force-driven biosensor platform.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4696-4706DOI: 10.1039/D1LC00884F, PaperAustin L. Culberson, Mason A. Chilmonczyk, Peter A. Kottke, Annie C. Bowles-Welch, Delta Ghoshal, Andrei G. FedorovRapid intracellular metabolomics from small numbers of cells.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4672-4684DOI: 10.1039/D1LC00568E, PaperPeter Thurgood, Gianmarco Concilia, Nhiem Tran, Ngan Nguyen, Adam J. Hawke, Elena Pirogova, Aaron R. Jex, Karlheinz Peter, Sara Baratchi, Khashayar KhoshmaneshWe use a smartphone-driven audio speaker to generate customised harmonic flow patterns in microfluidics. The system is programmable, simple, inexpensive, and biocompatible.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, Advance ArticleDOI: 10.1039/D1LC00691F, PaperApresio K. Fajrial, Adam Vega, Gazendra Shakya, Xiaoyun DingA frugal microfluidic pump is a fluid actuation system that is Fully self-sufficient, RobUst, Gravity-Assisted, and Low-cost (FRUGAL). The pump can generate pressure for versatile microfluidic applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4586-4595DOI: 10.1039/D1LC00737H, PaperJessica L. Sevetson, Brian Theyel, Diane Hoffman-Kim3-D spheroid cultures contain networks that develop by 9 days and develop increasingly complex network activity patterns as they mature. We demonstrate, for the first time, that spheroids exhibit network activity similar to in vivo network events.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4660-4671DOI: 10.1039/D1LC00663K, PaperChia-Yu Sung, Chi-Chien Huang, Yi-Sin Chen, Keng-Fu Hsu, Gwo-Bin LeeEV extraction, EV-encapsulated microRNA-21 isolation, reverse transcription, and digital PCR for microRNA quantification have been automated on the integrated microfluidic platform.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4707-4715DOI: 10.1039/D1LC00708D, PaperChi-Ju Kim, Jungmin Kim, Jonathan Sabaté del Río, Dong Yeob Ki, Junyoung Kim, Yoon-Kyoung ChoWe report a fully automated light transmission aggregometry (LTA) assay on a disc that can provide point-of-care testing to assess the function of platelets.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4637-4651DOI: 10.1039/D1LC00287B, PaperJose A. Santos, Alla A. Gimbel, Athanasios Peppas, James G. Truslow, Daniel A. Lang, Sivaprasad Sukavaneshvar, Derek Solt, Thomas J. Mulhern, Alex Markoski, Ernest S. Kim, James C.-M. Hsiao, Diana J. Lewis, Daniel I. Harjes, Christopher DiBiasio, Joseph L. Charest, Jeffrey T. BorensteinMulti-layer microfluidic oxygenator fabricated from three-dimensional branching blood flow networks mimicking physiological vasculature.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4566-4573DOI: 10.1039/D1LC00726B, PaperJie Hong, Jiahao Gong, Qian Li, Zhongshan Deng, Lin GuiAn on-chip liquid metal based micro-thermocouple based on a reversible bonding technology.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4549-4556DOI: 10.1039/D1LC00719J, CommunicationPengming Song, Chengfei Guo, Shaowei Jiang, Tianbo Wang, Patrick Hu, Derek Hu, Zibang Zhang, Bin Feng, Guoan ZhengWe demonstrate high-resolution ptychographic imaging in a flow cytometer configuration. The device complements the miniaturization provided by microfluidics and allows the integration of ptychographic microscopy into various lab-on-a-chip systems.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4487-4497DOI: 10.1039/D1LC00406A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.M. S. Gerlt, P. Ruppen, M. Leuthner, S. Panke, J. DualComprehensive integration of process steps into a miniaturised version of synthetic biology workflows remains a crucial task in automating the design of biosystems. We present an acoustofluidic chip, capable of automated medium exchange of bacteria.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4574-4585DOI: 10.1039/D1LC00602A, PaperKaitlyn Ramsay, Jae Levy, Pierangelo Gobbo, Katherine S. ElviraA microfluidic platform to build bespoke prototissues with collective behaviours that depend on the chemical composition of the biomaterial.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4652-4659DOI: 10.1039/D1LC00569C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lívia Ribeiro de Souza, Abir Al-TabbaaParallel junctions on a modular chip were used to produce high throughput monodisperse microcapsules for self-healing in cementitious materials.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4618-4628DOI: 10.1039/D1LC00440A, PaperChristopher Arble, Hongxuan Guo, Alessia Matruglio, Alessandra Gianoncelli, Lisa Vaccari, Giovanni Birarda, Andrei KolmakovA microchip for spectromicroscopy of biological materials employs a graphene enclosure to separate hydrated samples from a vacuum environment. Co-encapsulated lithographically defined hydrogel microstructures extend the lifetime of the hydrated state.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4498-4506DOI: 10.1039/D1LC00545F, PaperDimitri Radajewski, Liam Hunter, Xuefeng He, Ouassef Nahi, Johanna M. Galloway, Fiona C. MeldrumX-ray scattering techniques provide a powerful means of characterizing the formation of nanoparticles in solution.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4629-4636DOI: 10.1039/D1LC00556A, PaperZhenglin Li, Bongjun Yeom, Sung-Jin KimWe present a device that can scan and optimize the condition of a nanofilm coating in a parallel and ultrafast manner without using off-chip controllers.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4477-4486DOI: 10.1039/D1LC00643F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.T. Hamacher, J. T. W. Berendsen, J. E. van Dongen, R. M. van der Hee, J. J. L. M. Cornelissen, M. L. W. J. Broekhuijse, L. I. SegerinkPinched-flow fractionation removes viruses from (porcine) semen, which can increase the biosecurity of artificial insemination.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4414-4426DOI: 10.1039/D1LC00646K, PaperYishen Tian, Chunmiao Xu, Jiao Feng, Yueyue Huangfu, Kai Wang, Zhi-Ling ZhangPersonalized gel-droplet-encapsulated monocyte vaccines were prepared using an integrated chip and injected back into the hosts to induce CTL for the treatment of cancer.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4464-4476DOI: 10.1039/D1LC00790D, PaperBrenda L. K. Coles, Mahmoud Labib, Mahla Poudineh, Brendan T. Innes, Justin Belair-Hickey, Surath Gomis, Zongjie Wang, Gary D. Bader, Edward H. Sargent, Shana O. Kelley, Derek van der KooyA microfluidic approach combined with single-cell RNA sequencing enabled prospective identification of retinal stem cells and discovery of novel cell-surface markers and transcription factors.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4445-4454DOI: 10.1039/D1LC00422K, PaperDries Vloemans, Lorenz Van Hileghem, Wannes Verbist, Debby Thomas, Francesco Dal Dosso, Jeroen LammertynNovel passive microfluidic concept for precise volume metering and its use for high quality dried blood spot sample preparation.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4285-4310DOI: 10.1039/D1LC00438G, Critical ReviewBin Yang, Xingyu Jiang, Xueen Fang, Jilie KongThis review aims to help readers engage in wearable fundamental research or wearables commercial market by evaluating the biosensing performance.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4311-4329DOI: 10.1039/D1LC00618E, Critical ReviewYajing Zheng, Zengnan Wu, Ling Lin, Xiaonan Zheng, Ying Hou, Jin-Ming LinThis review focuses on diverse functional materials produced by microfluidic droplet technique and their applications in cell manipulation. It will inspire reader to explore cell biology by developing novel materials from an engineering perspective.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4401-4413DOI: 10.1039/D1LC00601K, PaperRob Ward, Sapna Ravindran, Mariela R. Otazo, Braden Cradock, Ebubekir Avci, Graeme Gillies, Christina Coker, Martin A. K. WilliamsAutomated microfluidics, laser tweezers, particle detection for pairwise particle stickiness measurements.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4357-4363DOI: 10.1039/D1LC00792K, CommunicationEkta Prajapati, Saurav Kumar, Shishir KumarWe report the Muscope, a miniature lensless holographic microscope suitable for on-chip integration.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4427-4436DOI: 10.1039/D1LC00524C, PaperAnindya Lal Roy, Hsi Nien Chiu, Konrad WalusA novel combinatorial thin film material formulation and deposition platform integrating microfluidic processing and drop-on-demand inkjet patterning capabilities.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4390-4400DOI: 10.1039/D1LC00749A, PaperBo Dai, Yan Long, Jiandong Wu, Shaoqi Huang, Yuan Zhao, Lulu Zheng, Chunxian Tao, Shiwei Guo, Francis Lin, Yongfeng Fu, Dawei Zhang, Songlin ZhuangA concentration gradient generator is demonstrated to generate ultra-long linear gradients, periodic gradients and droplets with various concentrations and produce drugs with different concentrations for drug screening applications.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4352-4356DOI: 10.1039/D1LC00699A, CommunicationRohit Varshney, Arshdeep Kaur Gill, Mujeeb Alam, Chinmayee Agashe, Debabrata PatraTo mimic the life-like complex behavior of microorganisms, enzyme-immobilized microfluidic microcapsules were fabricated to demonstrate the enzyme powered fluid actuation and buoyancy driven motility.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4437-4444DOI: 10.1039/D1LC00709B, PaperShiqi Jiang, Ronny Förster, Adrian Lorenz, Markus A. SchmidtWe report a 3D tracking platform based on dual-color position retrieval in a double-core microstructured optical fiber allowing full 3D reconstruction of the trajectory of a diffusing nanoparticle in a water-filled fiber-integrated microchannel.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4379-4389DOI: 10.1039/D1LC00610J, PaperShuzhang Liang, Chunyuan Gan, Yuguo Dai, Chaonan Zhang, Xue Bai, Shuailong Zhang, Aaron R. Wheeler, Huawei Chen, Lin FengInteraction between micro-objects is used to achieve the trapping, transport, and release of particles in the OET, enhancing the high-throughput transportation, and also to assemble some special microparticles structures.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4330-4351DOI: 10.1039/D1LC00658D, PerspectiveMercedes Vázquez, Laura Anfossi, Hadar Ben-Yoav, Lorena Diéguez, Thomas Karopka, Bartolomeo Della Ventura, Sara Abalde-Cela, Antonio Minopoli, Fabio Di Nardo, Vikas Kumar Shukla, Alexandra Teixeira, Asta Tvarijonaviciute, Lorena Franco-MartínezCost-effective technologies allow >85% economical savings, making clinical pathology more accessible worldwide.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4364-4378DOI: 10.1039/D1LC00419K, PaperEiyong Park, Sungjoon LimRF electronics is inkjet-printed directly onto a 3D printed microfluidic structure using surface modification for the high conductivity, high resolution, and enhanced the interaction between a RF part and a fluid material.The content of this RSS Feed (c) The Royal Society of Chemistry

Lab Chip, 2021, 21,4455-4463DOI: 10.1039/D1LC00676B, PaperSeungjin Kim, Si Hyung Jin, Hyun Gyu Lim, Byungjin Lee, Jaesung Kim, Jina Yang, Sang Woo Seo, Chang-Soo Lee, Gyoo Yeol JungCellular communication-based screening for strains with improved secretion.The content of this RSS Feed (c) The Royal Society of Chemistry