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RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • Shape-Adaptable Biodevices for Wearable and Implantable Applications
    by Qilong Zhao on September 27, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00569J, Tutorial Review Qilong Zhao, Chang Li, Ho Cheung Shum, Xuemin DuEmerging wearable and implantable biodevices have been significantly revolutionizing the diagnosis and treatment of diseases. However, the geometrical mismatch between tissues and biodevices remains a great challenge for achieving the...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Recent advance in microfluidic technologies for circulating tumor cells: From enrichment, single cell analysis to liquid biopsy for clinical applications
    by Haimeng Pei on September 27, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00577K, Tutorial Review Haimeng Pei, Lu Li, Zhaojun Han, Yiguo Wang, Bo TangCirculating tumor cells (CTCs) detach from primary or metastatic lesions and circulate in the peripheral blood, which is considered to be the cause of distant metastasis. CTC analysis as liquid...The content of this RSS Feed (c) The Royal Society of Chemistry

  • A Microfluidic Chip for Screening High-Producing Hybridomas at Single Cell Level
    by Weikai Zhang on September 24, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00847H, Paper Weikai Zhang, Ren Li, Fei Jia, Qin Li, Zhiyuan Hu, Zewen WeiHybridomas are a commonly used, or even the only option, for laboratory study and pilot production of monoclonal antibodies (mAbs), which are crucial for both targeted therapy and biomedical study....The content of this RSS Feed (c) The Royal Society of Chemistry

  • A new agarose-based microsystem to investigate cell response to prolonged confinement
    by A. Prunet on September 23, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00732C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. A. Prunet, S. Lefort, H. Delanoë-Ayari, B. Laperrousaz, G. Simon, C. Barentin, S. Saci, F. Argoul, B. Guyot, J.-P. Rieu, S. Gobert, V. Maguer-Satta, C. RivièreA unique tool to analyze the role of long-term effects of mechanical confinement in normal and pathological conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]

  • Selective cell encapsulation, lysis, pico-injection and size-controlled droplet generation using traveling surface acoustic waves in a microfluidic device
    by Kirk Mutafopulos on September 22, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00723D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Kirk Mutafopulos, Peter J. Lu, Ryan Garry, Pascal Spink, David A. WeitzWe generate traveling surface acoustic waves with an interdigital transducer to create droplets on-demand; encapsulate single cells; lyse cells and immediately encapsulate their contents; and pico-inject new materials into existing droplets.To cite this article before page numbers are assigned, use the DOI form of citation above.The […]

  • Nano-Localized Single-Cell Nano-Electroporation
    by Tuhin Subhra Santra on September 21, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00712A, Paper Tuhin Subhra Santra, Srabani Kar, Hwan-You Chang, Fan-Gang TsengThe ability to deliver foreign cargo into single living cells is of great interest in cell biology and therapeutic research. Here, an efficient and fast method of single or multiple...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Reduction of Taylor–Aris dispersion by lateral mixing for chromatographic applications
    by Eiko Y. Westerbeek on September 21, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00773K, Paper Eiko Y. Westerbeek, Johan G. Bomer, Wouter Olthuis, Jan C. T. Eijkel, Wim De MalscheWe demonstrate a method to reduce Taylor–Aris dispersion by lateral mixing in a newly designed silicon AC-electroosmotic flow mixer and with this improve a reverse-phase chromatographic separation of coumarins.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • On-chip density-based sorting of supercooled droplets and frozen droplets in continuous flow
    by Grace C. E. Porter on September 20, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00690D, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Grace C. E. Porter, Sebastien N. F. Sikora, Jung-uk Shim, Benjamin J. Murray, Mark D. TarnWe present a microfluidic platform for the continuous separation of frozen and unfrozen droplets based on differences in their density, allowing their sorting into different outlet channels with high efficiency towards applications in ice nucleation.To cite this article before page numbers are assigned, use the DOI form of […]

  • Fattening Chips: Hypertrophy, Feeding, and Fasting of Human White Adipocytes In Vitro
    by Benjamin D Pope on September 20, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00508H, Paper Benjamin D Pope, Curtis R Warren, Madeleine Dahl, Christina V Pizza, Douglas E Henze, Nina Sinatra, Grant Gonzalez, Huibin Chang, Qihan Liu, Aaron L Glieberman, John P Ferrier, Chad Cowan, Kevin Kit ParkerAdipose is a distributed organ that performs vital endocrine and energy homeostatic functions. Hypertrophy of white adipocytes is a primary mode of both adaptive and maladaptive weight gain in animals...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidics-enabled 96-well perfusion system for high-throughput tissue engineering and long-term all-optical electrophysiology
    by Lai Wei on September 20, 2020 at 11:00 pm

    Lab Chip, 2020, Accepted ManuscriptDOI: 10.1039/D0LC00615G, Paper Lai Wei, Weizhen Li, Emilia Entcheva, Zhenyu LiThis work demonstrates a novel high-throughput (HT) microfluidics-enabled uninterrupted perfusion system (HT-µUPS) and validates its use with chronic all-optical electrophysiology in human excitable cells. HT-µUPS consists of a soft multichannel...The content of this RSS Feed (c) The Royal Society of Chemistry

  • Vibration motor-integrated low-cost, miniaturized system for rapid quantification of red blood cell aggregation
    by Bumseok Namgung on September 17, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00619J, Paper Bumseok Namgung, Taewoo Lee, Justin Kok Soon Tan, Daren Kiat How Poh, Soyeon Park, Kevin Ziyang Chng, Rupesh Agrawal, Sung-Yong Park, Hwa Liang Leo, Sangho KimA low-cost portable device was developed with a coin vibration motor for quantification of red blood cell aggregation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Lysis and direct detection of coliforms on printed paper-based microfluidic devices
    by Sarah A. Snyder on September 17, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00665C, Paper Sarah A. Snyder, Mathew Boban, Chao Li, J. Scott VanEpps, Geeta Mehta, Anish TutejaThis article presents an integrated microfluidic coliform lysis and detection device featuring customizable omniphilic regions created by direct printing of omniphilic channels on an omniphobic, fluorinated paper.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Rapid purification of lung cancer cells in pleural effusion through spiral microfluidic channels for diagnosis improvement
    by Ping-Hsien Tsou on September 16, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00663G, Paper Ping-Hsien Tsou, Pei-Huan Chiang, Zi-Ting Lin, Hui-Chen Yang, Hsiang-Lin Song, Bor-Ran LiLung cancer is one of the leading causes of death worldwide.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Turning on/off satellite droplet ejection for flexible sample delivery on digital microfluidics
    by Haoran Li on September 16, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00701C, Paper Haoran Li, Ren Shen, Cheng Dong, Tianlan Chen, Yanwei Jia, Pui-In Mak, Rui P. MartinsConvenient electric control and electrode design allow flexible sample delivery on-chip in a wide range on microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • μCB-seq: microfluidic cell barcoding and sequencing for high-resolution imaging and sequencing of single cells
    by Tyler N. Chen on September 14, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00169D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Tyler N. Chen, Anushka Gupta, Mansi D. Zalavadia, Aaron StreetsWe present a platform for on-chip molecular barcoding that combines high-resolution imaging with genomic analysis, enabling multi-modal phenotypic measurements in single cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A novel sample delivery system based on circular motion for in situ serial synchrotron crystallography
    by Feng-Zhu Zhao on September 14, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00443J, Communication Feng-Zhu Zhao, Bo Sun, Li Yu, Qing-Jie Xiao, Zhi-Jun Wang, Liang-Liang Chen, Huan Liang, Qi-Sheng Wang, Jian-Hua He, Da-Chuan YinA microfluidic rotating-target sample delivery device based on circular motion for in situ serial crystallography is presented, which combines the advantages of circular motion, microfluidic technology and in situ diffraction.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • In-droplet cell separation based on bipolar dielectrophoretic response to facilitate cellular droplet assays
    by Song-I Han on September 13, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00710B, Paper Song-I Han, Can Huang, Arum HanNovel in-droplet label-free cell separation technology is presented in this paper by utilizing different dielectrophoretic responses of two distinct cell types, enabling broader ranges of cellular assays to be implemented in the droplet-based microfluidics system.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic salt precipitation: implications for geological CO2 storage
    by Tsai-Hsing Martin Ho on September 13, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00238K, Paper Tsai-Hsing Martin Ho, Peichun Amy TsaiNovel microfluidic visualizations reveal the simultaneous dynamics of salt nucleation and fluid drying rates while mimicking carbon capture and storage processes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Multiplexed analysis of neural cytokine signaling by a novel neural cell–cell interaction microchip
    by Mohammed A. A. Abdullah on September 10, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00401D, Paper Mohammed A. A. Abdullah, Nooshin Amini, Liwei Yang, Janet L. Paluh, Jun WangA neural cell–cell interaction microchip evaluates 10 cytokines released by neural stem cells and their morphology and biomarker expression.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Continuous and spontaneous nanoparticle separation by diffusiophoresis
    by Myungjin Seo on September 9, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00593B, Paper Myungjin Seo, Sungmin Park, Dokeun Lee, Hyomin Lee, Sung Jae KimWe present a simple but robust nanoparticle separation method based on spontaneously induced diffusiophoresis, which is operated in a continuous manner.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Deep-learning-assisted biophysical imaging cytometry at massive throughput delineates cell population heterogeneity
    by Dickson M. D. Siu on September 8, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00542H, Paper Dickson M. D. Siu, Kelvin C. M. Lee, Michelle C. K. Lo, Shobana V. Stassen, Maolin Wang, Iris Z. Q. Zhang, Hayden K. H. So, Godfrey C. F. Chan, Kathryn S. E. Cheah, Kenneth K. Y. Wong, Michael K. Y. Hsin, James C. M. Ho, Kevin K. TsiaAn optofluidic imaging cytometry strategy that hierarchically analyzes single-cell biophysical morphology beyond millions of cells at high sensitivity and specificity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal […]

  • Spontaneous droplet generation via surface wetting
    by Fengyi Liu on September 7, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00641F, Paper Fengyi Liu, Teng Xu, Wenjing Liu, Xiaoshan Zheng, Jian Xu, Bo MaA surface wetting-driven droplet generation microfluidic chip was developed and produces droplets spontaneously without any power source.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fabrication of 3D concentric amphiphilic microparticles to form uniform nanoliter reaction volumes for amplified affinity assays
    by Ghulam Destgeer on September 7, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00698J, Paper Ghulam Destgeer, Mengxing Ouyang, Chueh-Yu Wu, Dino Di CarloUniform fluid compartments are formed inside shape-coded amphiphilic particles using simple fluid exchange steps. This lab on a particle system enables multiplexed enzymatic reactions without cross talk to democratize cutting-edge biological assays.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Modified inverted selective plane illumination microscopy for sub-micrometer imaging resolution in polydimethylsiloxane soft lithography devices
    by Tienan Xu on September 7, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00598C, Paper Tienan Xu, Yean Jin Lim, Yujie Zheng, MoonSun Jung, Katharina Gaus, Elizabeth E. Gardiner, Woei Ming LeeSub-micrometer lightsheet imaging of live fibroblast cell in PDMS microdevices by m-iSPIM.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Channel innovations for inertial microfluidics
    by Wenlai Tang on September 6, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00714E, Critical Review Wenlai Tang, Shu Zhu, Di Jiang, Liya Zhu, Jiquan Yang, Nan XiangA review discussing the channel innovations for inertial microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A chip device to determine surface charge properties of confluent cell monolayers by measuring streaming potential
    by András Kincses on September 6, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00558D, Paper András Kincses, Ana R. Santa-Maria, Fruzsina R. Walter, László Dér, Nóra Horányi, Dóra V. Lipka, Sándor Valkai, Mária A. Deli, András DérChip device to monitor streaming potential of confluent cell layers reflecting cell surface charge important for the function of biological barriers.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Positional dependence of particles and cells in microfluidic electrical impedance flow cytometry: origin, challenges and opportunities
    by Hugo Daguerre on September 3, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00616E, Critical Review Hugo Daguerre, Miguel Solsona, Jonathan Cottet, Michaël Gauthier, Philippe Renaud, Aude BolopionIn impedance cytometry, particle trajectory can influence the measurements obtained. In this review, the physical grounds of this dependence are explained and both the challenges and the opportunities induced by this phenomenon are discussed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Integrated human organ-on-a-chip model for predictive studies of anti-tumor drug efficacy and cardiac safety
    by Alan Chramiec on September 3, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00424C, Paper Alan Chramiec, Diogo Teles, Keith Yeager, Alessandro Marturano-Kruik, Joseph Pak, Timothy Chen, Luke Hao, Miranda Wang, Roberta Lock, Daniel Naveed Tavakol, Marcus Busub Lee, Jinho Kim, Kacey Ronaldson-Bouchard, Gordana Vunjak-NovakovicIn a novel, integrated platform, integration of human bone tumor and cardiac tissues improved predictive accuracy of linsitinib efficacy and safety. This platform mimicked clinical trial results, unlike other pre-clinical models.To cite this article before page numbers are assigned, use the DOI form […]

  • Versatile biomimetic array assembly by phase modulation of coherent acoustic waves
    by Xuejia Hu on September 3, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00779J, Paper Xuejia Hu, Jiaomeng Zhu, Yunfeng Zuo, Dongyong Yang, Jianjian Zhang, Yanxiang Cheng, Yi YangVersatile biomimetic array assembly by phase modulation of coherent acoustic waves.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Integration of paper microfluidic sensors into contact lenses for tear fluid analysis
    by Rosalia Moreddu on September 3, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00438C, Paper Rosalia Moreddu, Mohamed Elsherif, Hadie Adams, Despina Moschou, Maria F. Cordeiro, James S. Wolffsohn, Daniele Vigolo, Haider Butt, Jonathan M. Cooper, Ali K. YetisenPaper microfluidic sensors were integrated into laser-inscribed contact lenses to provide an in situ platform for tear analysis with smartphone readouts.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • An ultra high-efficiency droplet microfluidics platform using automatically synchronized droplet pairing and merging
    by Han Zhang on September 3, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00757A, Paper Han Zhang, Adrian R. Guzman, Jose A. Wippold, Yuwen Li, Jing Dai, Can Huang, Arum HanThe integrated droplet platform combines curved microstructures that allow high-efficiency (99.9%) reflow of droplets and a droplet cleaving that automatically synchronizes paired droplets enabling high-efficiency (99.9%) downstream merging.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Needle-free delivery of fluids from compact laser-based jet injector
    by Jan Krizek on September 2, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00646G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Jan Krizek, Frédéric De Goumoëns, Paul Delrot, Christophe MoserWe present a needle-free jet injection from the minimally invasive device. The actuation mechanism is based on optical cavitation by a laser pulse transported via optical fibre.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Food safety monitoring of the pesticide phenthoate using a smartphone-assisted paper-based sensor with bimetallic Cu@Ag core–shell nanoparticles
    by Kamlesh Shrivas on September 2, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00515K, Paper Kamlesh Shrivas, Monisha, Sanyukta Patel, Santosh Singh Thakur, Ravi ShankarSmartphone-assisted paper-based sensor impregnated with citrate capped Cu@Ag core–shell NPs for selective determination of phenthoate pesticide in water and food samples is demonstrated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • 3× multiplexed detection of antibiotic resistant plasmids with single molecule sensitivity
    by G. G. Meena on September 1, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00640H, Paper G. G. Meena, R. L. Hanson, R. L. Wood, O. T. Brown, M. A. Stott, R. A. Robison, W. G. Pitt, A. T. Woolley, A. R. Hawkins, H. SchmidtThis work presents a rapid sample-to-answer system enabling multiplexed detection of three carbapenem antibiotic resistance plasmids with single molecule sensitivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • An engineered pancreatic cancer model with intra-tumoral heterogeneity of driver mutations
    by Hye-ran Moon on September 1, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00707B, Paper Hye-ran Moon, Altug Ozcelikkale, Yi Yang, Bennett D. Elzey, Stephen F. Konieczny, Bumsoo HanWe present a microfluidic tumor model with intra-tumoral heterogeneity of key driver mutations of pancreatic cancers including Kras, p16 and p53. We demonstrate its potential use of drug screening, and identify a new drug resistance mechanism.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic-prepared, monodisperse, X-ray-visible, embolic microspheres for non-oncological embolization applications
    by Cyrus W. Beh on August 31, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00098A, Paper Cyrus W. Beh, Yingli Fu, Clifford R. Weiss, Charles Hu, Aravind Arepally, Hai-Quan Mao, Tza-Huei Wang, Dara L. KraitchmanA multi-nozzle device incorporating pseudo-check valves rapidly generates monodisperse, spherical microbeads, impregnated with X-ray contrast agents, suitable for targeted embolic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Rapid and inexpensive microfluidic electrode integration with conductive ink
    by David McIntyre on August 31, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00763C, Communication David McIntyre, Ali Lashkaripour, Douglas DensmoreElectrode integration with off-the-shelf conductive ink provides a rapid and cost-effective method to develop sophisticated microfluidic prototypes in thermoplastics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Smart bio-gel optofluidic Mach–Zehnder interferometers multiphoton-lithographically customized with chemo-mechanical-opto transduction and bio-triggered degradation
    by Zhi-Shan Hou on August 31, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00718H, Paper Zhi-Shan Hou, Yun-Lu Sun, Qi-Song Li, Xudong Fan, Rong ChengChemical-signal-responsive optofluidic Mach–Zehnder-interferometric optical switch customized by FsLDW.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Time-resolved microwell cell-pairing array reveals multiple T cell activation profiles
    by Anna Desalvo on August 30, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00628A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Anna Desalvo, Faith Bateman, Edward James, Hywel Morgan, Tim ElliottTime-controlled stimulation of lymphocytes arrayed in microwells upon contact with opposing surface covered by a monolayer of antigen presenting cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Single mode operation and ultrawide tuning of on-chip optofluidic dye lasers
    by Lin Chen on August 30, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00742K, Paper Lin Chen, Chenming Zhao, Liying Liu, Lei XuAn on-chip optofluidic dye laser operating in fundamental transverse mode was tuned over more than 450 nm.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Adaptable pulsatile flow generated from stem cell-derived cardiomyocytes using quantitative imaging-based signal transduction
    by Tongcheng Qian on August 30, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00546K, Paper Tongcheng Qian, Daniel A. Gil, Emmanuel Contreras Guzman, Benjamin D. Gastfriend, Kelsey E. Tweed, Sean P. Palecek, Melissa C. SkalaBiologically-driven pulsatile flow is generated by quantitative imaging of contractions from human pluripotent stem cell-derived heart cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Single ascospore detection for the forecasting of Sclerotinia stem rot of canola
    by Pedro A. Duarte on August 30, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00426J, Paper Pedro A. Duarte, Lukas Menze, Gaser N. Abdelrasoul, Shari Yosinski, Zak Kobos, Riley Stuermer, Mark Reed, Jian Yang, Xiujie S. Li, Jie ChenSmart-agriculture technologies comprise a set of management systems designed to sustainably increase the efficiency and productivity of farming.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A microfluidic chip for rapid analysis of DNA melting curves for BRCA2 mutation screening
    by Xuyan Lin on August 27, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00624F, Paper Xuyan Lin, Stefan NaglA microfluidic chip for rapid space domain melting curve analysis of DNA fragments was developed and applied for the screening of a breast cancer gene.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Exosome trapping and enrichment using a sound wave activated nano-sieve (SWANS)
    by Ruhollah Habibi on August 27, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00623H, Paper Ruhollah Habibi, Vincent He, Sara Ghavamian, Alex de Marco, Tzong-Hsien Lee, Marie-Isabel Aguilar, Dandan Zhu, Rebecca Lim, Adrian NeildMechanically activated packed-bed of beads (SWANS) traps and rapidly enriches the concentration of exosomes, a form of extracellular vesicles, while preserves the integrity of the lipid bilayer membrane. Also, larger beads perform better in capturing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]

  • A 96-well format microvascularized human lung-on-a-chip platform for microphysiological modeling of fibrotic diseases
    by Joscelyn C. Mejías on August 25, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00644K, Paper Joscelyn C. Mejías, Michael R. Nelson, Olivia Liseth, Krishnendu RoyA 3D microvascularized lung-on-a-chip device for modeling pulmonary diseases.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Fully-automated and field-deployable blood leukocyte separation platform using multi-dimensional double spiral (MDDS) inertial microfluidics
    by Hyungkook Jeon on August 24, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00675K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Hyungkook Jeon, Bakr Jundi, Kyungyong Choi, Hyunryul Ryu, Bruce D. Levy, Geunbae Lim, Jongyoon HanA fully-automated and field-deployable blood leukocyte separation platform based on a new type of inertial microfluidic device, multi-dimensional double spiral (MDDS) device, which achieves sample focusing and separation in a single device without sheath flow.To cite this article before page numbers are assigned, […]

  • Pore-scale multiple-contact miscibility measurements in a microfluidic chip
    by Hanbang Zou on August 20, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00659A, Paper Hanbang Zou, Hanwen Kang, Anja C. Slim, Adrian NeildA microfluidic approach to the measurements of the onset of multiple-contact miscibility and quantification of the role of different wetting conditions in the displacement of reservoir fluid.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Chitosan–polydopamine hydrogel complex: a novel green adhesion agent for reversibly bonding thermoplastic microdevice and its application for cell-friendly microfluidic 3D cell culture
    by Kieu The Loan Trinh on August 19, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00621A, Paper Kieu The Loan Trinh, Nguyen Xuan Thanh Le, Nae Yoon LeeA chitosan–polydopamine hydrogel complex was introduced as an UV-assisted biocompatible adhesion agent for fabricating a PMMA microdevice employed in spheroid formation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Separating extracellular vesicles and lipoproteins via acoustofluidics
    by Mengxi Wu on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3472-3472DOI: 10.1039/D0LC90093A, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Mengxi Wu, Chuyi Chen, Zeyu Wang, Hunter Bachman, Yingshi Ouyang, Po-Hsun Huang, Yoel Sadovsky, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Three-dimensional numerical simulation and experimental investigation of boundary-driven streaming in surface acoustic wave microfluidics
    by Chuyi Chen on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3469-3469DOI: 10.1039/D0LC90090G, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Chuyi Chen, Steven Peiran Zhang, Zhangming Mao, Nitesh Nama, Yuyang Gu, Po-Hsun Huang, Yun Jing, Xiasheng Guo, Francesco Costanzo, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Acoustic tweezers based on circular, slanted-finger interdigital transducers for dynamic manipulation of micro-objects
    by Putong Kang on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3468-3468DOI: 10.1039/D0LC90089C, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Putong Kang, Zhenhua Tian, Shujie Yang, Wenzhuo Yu, Haodong Zhu, Hunter Bachman, Shuaiguo Zhao, Peiran Zhang, Zeyu Wang, Ruoyu Zhong, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: On-chip stool liquefaction via acoustofluidics
    by Shuaiguo Zhao on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3474-3474DOI: 10.1039/D0LC90095H, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Shuaiguo Zhao, Weihua He, Zhehan Ma, Peiyao Liu, Po-Hsun Huang, Hunter Bachman, Lin Wang, Shujie Yang, Zhenhua Tian, Zeyu Wang, Yuyang Gu, Zhemiao Xie, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: Cell lysis via acoustically oscillating sharp edges
    by Zeyu Wang on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3471-3471DOI: 10.1039/D0LC90092C, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Zeyu Wang, Po-Hsun Huang, Chuyi Chen, Hunter Bachman, Shuaiguo Zhao, Shujie Yang, Tony J. HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: High-throughput cell focusing and separation via acoustofluidic tweezers
    by Mengxi Wu on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3470-3470DOI: 10.1039/D0LC90091E, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Mengxi Wu, Kejie Chen, Shujie Yang, Zeyu Wang, Po-Hsun Huang, John Mai, Zeng-Yao Li, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Correction: An acoustofluidic device for efficient mixing over a wide range of flow rates
    by Hunter Bachman on August 18, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3473-3473DOI: 10.1039/D0LC90094J, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Hunter Bachman, Chuyi Chen, Joseph Rufo, Shuaiguo Zhao, Shujie Yang, Zhenhua Tian, Nitesh Nama, Po-Hsun Huang, Tony Jun HuangThe content of this RSS Feed (c) The Royal Society of Chemistry

  • Microfluidic label-free bioprocessing of human reticulocytes from erythroid culture
    by Kerwin Kwek Zeming on August 13, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3445-3460DOI: 10.1039/C9LC01128E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Kerwin Kwek Zeming, Yuko Sato, Lu Yin, Nai-Jia Huang, Lan Hiong Wong, Hooi Linn Loo, Ying Bena Lim, Chwee Teck Lim, Jianzhu Chen, Peter R. Preiser, Jongyoon HanDevelopments in Dean flow fractionation (DFF) and deterministic lateral displacement (DLD) for label-free purification of cultured RBCs from human hematopoietic stem cells. An advancement in sorting and closed-loop manufacturing of viable human RBCs.The […]

  • Distance-based paper/PMMA integrated ELISA-chip for quantitative detection of immunoglobulin G
    by Mahlet Fasil Abate on August 11, 2020 at 11:00 pm

    Lab Chip, 2020, Advance ArticleDOI: 10.1039/D0LC00505C, Paper Mahlet Fasil Abate, Metages Gashaw Ahmed, Xingrui Li, Chaoyong Yang, Zhi ZhuA simple, portable, and equipment-free paper/PMMA integrated ELISA-chip was developed with visual distance readout for sensitive, rapid, and quantitative detection of IgG, which holds great promise for POC testing in resource-limited setup.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Acoustofluidic multi-well plates for enrichment of micro/nano particles and cells
    by Pengzhan Liu on August 10, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3399-3409DOI: 10.1039/D0LC00378F, Paper Pengzhan Liu, Zhenhua Tian, Nanjing Hao, Hunter Bachman, Peiran Zhang, Junhui Hu, Tony Jun HuangControllable enrichment of micro/nanoscale objects plays a significant role in many biomedical and biochemical applications, such as increasing the detection sensitivity of assays, or improving the structures of bio-engineered tissues.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Neutrophilic infiltration in organ-on-a-chip model of tissue inflammation
    by Nikolce Gjorevski on August 5, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3365-3374DOI: 10.1039/D0LC00417K, Paper Nikolce Gjorevski, Blandine Avignon, Régine Gérard, Lauriane Cabon, Adrian B. Roth, Michael Bscheider, Annie MoisanWe describe a microphysiological model of intestinal inflammation, which incorporates and captures the functional interactions between an epithelial barrier, resident macrophages, infiltrating neutrophils, and extrcellular matrix degradation products.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Finger-powered fluidic actuation and mixing via MultiJet 3D printing
    by Eric Sweet on August 3, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3375-3385DOI: 10.1039/D0LC00488J, Paper Eric Sweet, Rudra Mehta, Yifan Xu, Ryan Jew, Rachel Lin, Liwei LinEntirely 3D-printed sources of human-powered, electricity-free fluidic actuation (∼100–3000 μL min−1) and mixing are developed.The content of this RSS Feed (c) The Royal Society of Chemistry

  • SNAPflex: a paper-and-plastic device for instrument-free RNA and DNA extraction from whole blood
    by Nikunja Kolluri on August 3, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3386-3398DOI: 10.1039/D0LC00277A, Paper Nikunja Kolluri, Nikolas Albarran, Andy Fan, Alex Olson, Manish Sagar, Anna Young, José Gomez-Marquez, Catherine M. KlapperichNucleic acid amplification tests (NAATs), which amplify and detect pathogen nucleic acids, are vital methods to diagnose diseases, particularly in cases where patients exhibit low levels of infection.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Development of a cardiac-and-piezoelectric hybrid system for application in drug screening
    by Yun-Han Huang on August 2, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3423-3434DOI: 10.1039/D0LC00433B, Paper Yun-Han Huang, Chiou-Fong Yang, Yu-Hsiang HsuA cardiac-and-piezoelectric hybrid system for drug screening: a new method to electrically monitor contractility of cardiomyocytes in vitro using a piezoelectric membrane.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A modular microarray imaging system for highly specific COVID-19 antibody testing
    by Per Niklas Hedde on August 2, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3302-3309DOI: 10.1039/D0LC00547A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Per Niklas Hedde, Timothy J. Abram, Aarti Jain, Rie Nakajima, Rafael Ramiro de Assis, Trevor Pearce, Algis Jasinskas, Melody N. Toosky, Saahir Khan, Philip L. Felgner, Enrico Gratton, Weian ZhaoThe TinyArray imager, a robust inexpensive portable imaging device, can detect antibodies against SARS-CoV-2 based on coronavirus antigen microarrays.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Modeling iontophoretic drug delivery in a microfluidic device
    by Maryam Moarefian on July 29, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3310-3321DOI: 10.1039/D0LC00602E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. Maryam Moarefian, Rafael V. Davalos, Danesh K. Tafti, Luke E. Achenie, Caroline N. JonesIontophoresis employs low-intensity electrical voltage and continuous constant current to direct a charged drug into a tissue.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Compact 256-channel multi-well microelectrode array system for in vitro neuropharmacology test
    by Daejeong Kim on July 28, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3410-3422DOI: 10.1039/D0LC00384K, Paper Daejeong Kim, Hongki Kang, Yoonkey NamIn this study, we developed a compact multi-well MEA with commercial ASIC based in vitro high-throughput recording system to investigate electrophysiological drug response.The content of this RSS Feed (c) The Royal Society of Chemistry

  • A 3D-printed metal column for micro gas chromatography
    by Sooyeol Phyo on July 27, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3435-3444DOI: 10.1039/D0LC00540A, Paper Sooyeol Phyo, Sung Choi, Jaeheok Jang, Sun Choi, Jiwon LeeA square spiral 1 m-long column for gas mixture separation was 3D-printed out with the dimensions of 3.4 × 3.3 × 0.2, followed by pre-treatment and stationary phase coating.The content of this RSS Feed (c) The Royal Society of Chemistry

  • NanoPADs and nanoFACEs: an optically transparent nanopaper-based device for biomedical applications
    by Binbin Ying on July 27, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3322-3333DOI: 10.1039/D0LC00226G, Paper Binbin Ying, Siwan Park, Longyan Chen, Xianke Dong, Edmond W. K. Young, Xinyu LiuA highly transparent nanopaper-based microfluidic device for chemical/biosensing and cell culture, which is branded as nanopaper-based analytical devices (nanoPADs) and nanofibrillated adherent cell-culture platforms (nanoFACEs).The content of this RSS Feed (c) The Royal Society of Chemistry

  • Pulmonary-arterial-hypertension (PAH)-on-a-chip: fabrication, validation and application
    by Taslim A. Al-Hilal on July 27, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3334-3345DOI: 10.1039/D0LC00605J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. Taslim A. Al-Hilal, Ali Keshavarz, Hossam Kadry, Behnaz Lahooti, Ahmed Al-Obaida, Zhenya Ding, Wei Li, Roger Kamm, Ivan F. McMurtry, Tim Lahm, Eva Nozik-Grayck, Kurt R. Stenmark, Fakhrul AhsanCurrent animal and cellular models only partially recapitulate the pathophysiology of PAH. Our PAH-on-a-chip model can mimic the major pathologies of PAH such as pulmonary arterial remodeling and sex disparity and help […]

  • Scaling of deterministic lateral displacement devices to a single column of bumping obstacles
    by Weibin Liang on July 26, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3461-3467DOI: 10.1039/D0LC00570C, Paper Weibin Liang, Robert H. Austin, James C. SturmScaling DLD array devices to a single column of bumping obstacles to increase throughput per area and minimize device area.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Electro-responsive hydrogel-based microfluidic actuator platform for photothermal therapy
    by Jang Ho Ha on July 26, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3354-3364DOI: 10.1039/D0LC00458H, Paper Jang Ho Ha, Ha Hee Shin, Hyung Woo Choi, Jae Hyun Lim, Sung Joon Mo, Christian D. Ahrberg, Jong Min Lee, Bong Geun ChungElectrical stimuli play an important role in regulating the delivery of plasmonic nanomaterials with cancer targeting peptides.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Centrifugal microfluidic device for the high-throughput synthesis of Pd@AuPt core–shell nanoparticles to evaluate the performance of hydrogen peroxide generation
    by Hau Van Nguyen on July 12, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3293-3301DOI: 10.1039/D0LC00461H, Paper Hau Van Nguyen, Ki Yoon Kim, Hyobin Nam, Seung Yong Lee, Taekyung Yu, Tae Seok SeoWe propose a novel high-throughput screening platform using a centrifugal microfluidic device for producing combinatorial tri-metallic catalysts.The content of this RSS Feed (c) The Royal Society of Chemistry

  • Reciprocating flow-assisted nucleic acid purification using a finger-actuated microfluidic device
    by Juhwan Park on June 24, 2020 at 11:00 pm

    Lab Chip, 2020, 20,3346-3353DOI: 10.1039/D0LC00432D, Paper Juhwan Park, Dong Hyun Han, Sang-Hyun Hwang, Je-Kyun ParkA finger-actuated microfluidic reciprocator was developed and exploited to improve the recovery rate of nucleic acid purification in a finger-actuated microfluidic device.The content of this RSS Feed (c) The Royal Society of Chemistry

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Microsystems & Nanoengineering - nature.com technology Microsystems & Nanoengineering is an international open access journal, publishing original articles and reviews covering all aspects of microsystems and nanoengineering from fundamental to applied research.

  • An active self-cleaning surface system for photovoltaic modules using anisotropic ratchet conveyors and mechanical vibration
    by Di Sun on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-00197-zMicro-patterned, self-cleaning solar panels can maintain their efficiency with little resources or human intervention. The efficiency of solar panels, often built on arid landscapes, can be reduced by up to 40% as dust accumulates on the panels. Di Sun and Karl F. Böhringer, from the United States’ University of Washington, created a micro-patterned solar panel glass that incorporates hydrophilic, curved ‘rungs’ on a hydrophobic surface. When mechanical vibration is applied to the […]

  • Pyrrhotite Fe1−xS microcubes as a new anode material in potassium-ion batteries
    by Yang Xu on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-00188-0Energy storage: Developing electrodes for potassium-based batteries. Microcubes of iron sulfide pyrrhotite constitute a promising electrode material for potassium-ion batteries. Potassium-ion (K+) batteries are being investigated as an alternative to lithium-ion batteries due to potassium’s abundance and low cost, but a challenge lies in discovering suitable materials for the battery’s electrodes. Yang Xu, and a team from University College London, United Kingdom, and Northeast Normal […]

  • Handheld endomicroscope using a fiber-optic harmonograph enables real-time and in vivo confocal imaging of living cell morphology and capillary perfusion
    by Kyungmin Hwang on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-00182-6A fiber-optic microscopy system collects real-time imaging data with high resolution from within the tissue of living organisms. Endoscopically-coupled microscopes systems have become increasingly commonplace, but these systems often suffer from stability issues and trade-offs in terms of imaging speed and resolution. Researchers led by Ki-Hun Jeong of the KAIST Institute of Health Science and Technology have now developed an endomicroscope based on a system known as a Lissajous fiber […]

  • Sacrificial layer-assisted nanoscale transfer printing
    by Junshan Liu on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-00195-1Transfer printing is an emerging assembly technique for flexible and stretchable electronics, and a breakthrough method has been developed that allows transfer printing at the nanoscale by means of a weak-adhesion intermediate (sacrificial) layer. Although transfer printing has gained considerable attention for transferring various classes of materials with a wide range of geometries and configurations from one substrate to another, very few methods have allowed such printing at the […]

  • Capillary-force-induced collapse lithography for controlled plasmonic nanogap structures
    by Inki Kim on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-0177-8An innovative technique—capillary-force-induced collapse lithography (CCL)—has been developed to easily fabricate plasmonic nano-gap structures, which with a nano-gap of

  • Parylene photonics: a flexible, broadband optical waveguide platform with integrated micromirrors for biointerfaces
    by Jay W. Reddy on September 21, 2020 at 12:00 am

    Microsystems & Nanoengineering, Published online: 21 September 2020; doi:10.1038/s41378-020-00186-2A flexible and biocompatible optical platform is demonstrated that can be used for biophotonic applications. Delivering light into tissue is important for biological imaging and manipulation, such as for medical treatments or monitoring brain activity. However, traditional light delivery systems are composed of rigid materials, which can damage biological tissue. Here, a team from Carnegie Mellon University led by Maysamreza Chamanzar demonstrates a photonic platform composed of […]