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RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • The biomolecular corona of gold nanoparticles in a controlled microfluidic environment
    by Luca Digiacomo on June 16, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00341J, PaperLuca Digiacomo, Sara Palchetti, Francesca Giulimondi, Daniela Pozzi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Giulio CaraccioloNanoparticles (NPs) exposed to biological media are coated by proteins and other biomolecules forming a biomolecular corona (BC) on the particle surface. Recent studies have shown that shear stress as...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Polymeric microfluidic continuous flow mixer combined with hyperspectral FT-IR imaging for studying rapid biomolecular events
    by Hyukjin Jang on June 16, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00182D, PaperHyukjin Jang, Ashtamurthy Pawate, Rohit Bhargava, Paul KenisEarly reaction intermediates in protein folding, such as those resulting in β-amyloid formation due to transient misfolding, emerge within a few hundred microseconds. Here, we report method to obtain sub-millisecond...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Electronic profiling of membrane antigen expression via immunomagnetic cell manipulation
    by Ozgun Civelekoglu on June 13, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00297A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Ozgun Civelekoglu, Ningquan Wang, Mert Boya, Tevhide Ozkaya-Ahmadov, Ruxiu Liu, A. Fatih SariogluA disposable magnetophoretic cytometer with a multiplexed electronic readout for quantitative membrane antigen profiling.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Natural Killer Cell Migration Control in Microchannels by Perturbations and Topography
    by Yuanhao Xu on June 13, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00356H, PaperYuanhao Xu, Stella PangNatural killer (NK) cells are lymphocytes which serve an important role in immune system by recognizing and killing potentially malign cells without antigen sensitization, and could be utilized in cancer...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Traveling surface acoustic wave (TSAW) microfluidic fluorescence activated cell sorter (μFACS)
    by K. Mutafopulos on June 12, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00163H, PaperK. Mutafopulos, P. Spink, C. D. Lofstrom, P. J. Lu, H. Lu, J. C. Sharpe, T. Franke, D. A. WeitzWe report a microfluidic fluorescence activated cell-sorting (μFACS) device that employs traveling surface acoustic waves (TSAW) to sort cells at rates comparable to conventional jet-in-air FACS machines, with high purity and viability.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A nanochannel through a plasmonic antenna gap: an integrated device for single particle counting
    by Irene Fernandez-Cuesta on June 10, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00186G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Irene Fernandez-Cuesta, Melanie Maputol West, Enrica Montinaro, Adam Schwartzberg, Stefano CabriniA gold bowtie nanoantenna integrated with a 30 nm × 30 nm nanochannel for single particle detection and counting in real time.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Single-cell RT-LAMP mRNA detection by integrated droplet sorting and merging
    by Meng Ting Chung on June 7, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00161A, PaperMeng Ting Chung, Katsuo Kurabayashi, Dawen CaiWe present a droplet-based microfluidic platform that permits seamless on-chip droplet sorting and merging, which enables completing multi-step reaction assays within a short time, and demonstrate detection of specific single-cell mRNA expressions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A Facile Multi-Material Direct Laser Writing Strategy
    by Andrew C. Lamont on June 6, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00398C, CommunicationAndrew C. Lamont, Michael A. Restaino, Matthew J. Kim, Ryan D SocholDirect Laser Writing (DLW) is a three-dimensional (3D) manufacturing technology that offers vast architectural control at submicron scales, yet remains limited in cases that demand microstructures comprising more than one...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Measurement of the magnetic susceptibility of subtle paramagnetic solutions using the diamagnetic repulsion of polymer microparticles
    by Bong Hwan Jang on June 6, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00245F, PaperBong Hwan Jang, Seyong Kwon, Joo H. KangThe diamagnetic repulsion of polymer microspheres in a microfluidic platform enables the discrimination of magnetic susceptibility of subtle paramagnetic solutions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D-printing Enabled Micro-assembly of Microfluidic Electroporation System for 3D Tissue Engineering
    by Qingfu Zhu on June 6, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00046A, PaperQingfu Zhu, Megan Elizabeth Hamilton, Bryan Vasquez, Mei HeElectro-transfection is an essential workhorse tool for regulating cellular responses and engineering cellular materials in tissue engineering. However, existing approaches, including microfluidic platforms and bench top methods, are only able...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Nip the bubble in the bud: a guide to avoid gas nucleation in microfluidics
    by Iago Pereiro on June 5, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00211A, Tutorial ReviewIago Pereiro, Anna Fomitcheva Khartchenko, Lorenzo Petrini, Govind V. KaigalaA guide on the underlying physics, prevention and removal strategies of undesirable bubbles in microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Integrating user behavior with engineering design of point-of-care diagnostic devices: theoretical framework and empirical findings
    by Samiksha Nayak on June 5, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00188C, PaperSamiksha Nayak, Tiffany Guo, Javier Lopez-Rios, Cody Lentz, Siddarth Arumugam, Joshua Hughes, Curtis Dolezal, Vincent Linder, Alex Carballo-Diéguez, Iván C. Balán, Samuel K. SiaAs point-of-care diagnostic devices become increasingly available to untrained users, it will be critical to understand how user behavior can best guide the engineering design process.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multi-chamber petaloid root-growth chip for the non-destructive study of the development and physiology of the fibrous root system of Oryza sativa
    by Hui Hui Chai on June 4, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00396G, PaperHui Hui Chai, Feng Chen, Shu Jie Zhang, Ya Dan Li, Zhi Song Lu, Yue Jun Kang, Ling YuA multi-chamber petaloid root-growth microfluidic chip was developed for the non-destructive investigation of the effect of different drought stress conditions on the fibrous root system development of a single seedling.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A pH-regulated drug delivery dermal patch for targeting infected regions in chronic wounds
    by Hongjie Jiang on June 3, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00206E, PaperHongjie Jiang, Manuel Ochoa, Jose Fernando Waimin, Rahim Rahimi, Babak ZiaieA low-cost, passive, and flexible dermal patch using wound pH to regulate topical drug delivery in chronic wounds.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Remotely controlled nanofluidic implantable platform for tunable drug delivery
    by Nicola Di Trani on June 2, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00394K, PaperNicola Di Trani, Antonia Silvestri, Giacomo Bruno, Thomas Geninatti, Corrine Ying Xuan Chua, April Gilbert, Giulia Rizzo, Carly S. Filgueira, Danilo Demarchi, Alessandro GrattoniAn implantable nanofluidic device for remote controlled drug delivery.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Rational design of a high-throughput droplet sorter
    by Simon S. Schütz on June 2, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00149B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Simon S. Schütz, Thomas Beneyton, Jean-Christophe Baret, Tobias M. SchneiderThe high-throughput selection of individual droplets is an essential function in droplet-based microfluidics.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A homobifunctional imidoester-based microfluidic system for simultaneous DNA and protein isolation from solid or liquid biopsy samples
    by Yoon Ok Jang on May 30, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00367C, PaperYoon Ok Jang, Choong Eun Jin, Eun Hwa Choi, Joong Ho Shin, Jihoon Kweon, Bonhan Koo, Seok-Byung Lim, Sei Won Lee, Yong ShinThe isolation of bio-molecules such as proteins and nucleic acids is a necessary step for both diagnostic and analytical processes in the broad fields of research and clinical applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Antifouling digital microfluidics using lubricant infused porous film
    by Hongyao Geng on May 30, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00289H, PaperHongyao Geng, Sung Kwon ChoWe report antifouling digital microfluidics by introducing a lubricant infused porous film to electrowetting, showing high performance and robustness even in long cyclic operations without fouling for a variety of bio-solutions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Ultra-compact, automated microdroplet radiosynthesizer
    by Jia Wang on May 29, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00438F, PaperJia Wang, Philip H. Chao, R. Michael van DamAn ultra-compact microdroplet platform was developed for multi-step synthesis of radiolabeled tracers for positron emission tomography (PET).To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Self-aligning Tetris-Like (TILE) modular microfluidic platform for mimicking multi-organ interactions
    by Louis Jun Ye Ong on May 29, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00160C, PaperLouis Jun Ye Ong, Terry Ching, Lor Huai Chong, Seep Arora, Huan Li, Michinao Hashimoto, Ramanuj DasGupta, Po Ki Yuen, Yi-Chin TohModular multi-organ perfusion systems offer the unique opportunity to customize different physiological systemic interactions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Continuous micellar electrokinetic focusing of neutral species driven by ion concentration polarization
    by Beatrise Berzina on May 27, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00327D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Beatrise Berzina, Robbyn K. AnandHere, we demonstrate continuous electrokinetic focusing and separation of uncharged compounds by their partition into an ionic micellar phase.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Non-aqueous continuous-flow electrophoresis (NACFE): potential separation complement for continuous-flow organic synthesis
    by Nikita A. Ivanov on May 27, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00460B, CommunicationNikita A. Ivanov, Yimo Liu, Sven Kochmann, Sergey N. KrylovWe introduce non-aqueous continuous-flow electrophoresis (NACFE) in which organic electrolyte and solvent are utilized to maintain steady-state continuous-flow separation of multiple hydrophobic organic compounds into individual molecular streams.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Integrated elastomer-based device for measuring the mechanics of adherent cell monolayers
    by Francesca Sorba on May 21, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2138-2146DOI: 10.1039/C9LC00075E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Francesca Sorba, Alexandre Poulin, Réal Ischer, Herbert Shea, Cristina Martin-OlmosWe developed an integrated device for measuring the Young's modulus of adherent cell monolayers over time within a physiological environment.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Automated serial dilutions for high-dynamic-range assays enabled by fill-level-coupled valving in centrifugal microfluidics
    by Peter Juelg on May 19, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00092E, PaperPeter Juelg, Mara Specht, Elena Kipf, Michael Lehnert, Cornelia Eckert, Mark Keller, Tobias Hutzenlaub, Felix von Stetten, Roland Zengerle, Nils PaustTime-independent, serial valving under rotation on centrifugal microfluidic platforms by a fill-level-coupled temperature change rate (FLC-TCR) actuated principle.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Rapid separation and identification of beer spoilage bacteria by inertial microfluidics and MALDI-TOF mass spectrometry
    by Mark R. Condina on May 16, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1961-1970DOI: 10.1039/C9LC00152B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mark R. Condina, Brooke A. Dilmetz, Sajad Razavi Bazaz, Jon Meneses, Majid Ebrahimi Warkiani, Peter HoffmannMicrofluidics and MALDI-TOF MS is a rapid, high-throughput, and accurate method for the identification of beer spoilage bacteria.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D printed microfluidic device for online detection of neurochemical changes with high temporal resolution in human brain microdialysate
    by Isabelle C. Samper on May 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2038-2048DOI: 10.1039/C9LC00044E, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Isabelle C. Samper, Sally A. N. Gowers, Michelle L. Rogers, De-Shaine R. K. Murray, Sharon L. Jewell, Clemens Pahl, Anthony J. Strong, Martyn G. BoutelleMicrofluidic devices optimised for real-time monitoring of the human brain.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • The Art in Science of MicroTAS 2018
    by Gregory A. Cooksey on May 14, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2058-2059DOI: 10.1039/C9LC90052G, EditorialGregory A. CookseyNam-Trung Nguyen from Griffith University, Australia, was the winner of the 2018 MicroTAS Art in Science competition. He received the award certificate from Simon Neil from Lab on a Chip and Greg Cooksey from NIST.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic droplet liquid reactors for active pharmaceutical ingredient crystallization by diffusion controlled solvent extraction
    by Robert M. Tona on May 13, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2127-2137DOI: 10.1039/C9LC00204A, PaperRobert M. Tona, Thomas A. O. McDonald, Nima Akhavein, Jonathan D. Larkin, David LaiMicrofluidic solvent/antisolvent droplet liquid reactors utilize diffusion-controlled extraction to tailor particle size and morphology to optimize drug manufacturability and bioavailability.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Feedback control for shaping density distributions of colloidal particles in microfluidic devices
    by Yu Gao on May 13, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00192A, PaperYu Gao, Richard LakerveldAn automated feedback control strategy for directed self-assembly is developed to obtain a desired density distribution.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Controlled co-precipitation of biocompatible colorant-loaded nanoparticles by microfluidics for natural color drinks
    by Linlin Kong on May 13, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2089-2095DOI: 10.1039/C9LC00240E, PaperLinlin Kong, Ran Chen, Xingzheng Wang, Chun-Xia Zhao, Qiushui Chen, Mingtan Hai, Dong Chen, Zhenzhong Yang, David A. WeitzControlled co-precipitation of biocompatible colorant-loaded nanoparticles in microfluidic channels for natural color drinks.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Effective bioprinting resolution in tissue model fabrication
    by Amir K. Miri on May 12, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2019-2037DOI: 10.1039/C8LC01037D, PaperAmir K. Miri, Iman Mirzaee, Shabir Hassan, Shirin Mesbah Oskui, Daniel Nieto, Ali Khademhosseini, Yu Shrike ZhangWe compare current bioprinting technologies for their effective resolutions in the fabrication of micro-tissues towards construction of biomimetic microphysiological systems.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Real-time optical fiber sensors based on light diffusing microlens arrays
    by Mohamed Elsherif on May 12, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2060-2070DOI: 10.1039/C9LC00242A, CommunicationMohamed Elsherif, Rosalia Moreddu, Muhammad Umair Hassan, Ali K. Yetisen, Haider ButtThe applications of optical fibers are impeded in implantable medical diagnostics due to incompatibility with biological tissues, and immune reaction in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic-controlled optical router for lab on a chip
    by Jiri Dietvorst on May 12, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2081-2088DOI: 10.1039/C9LC00143C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Jiri Dietvorst, Jeroen Goyvaerts, Tobias Nils Ackermann, Erica Alvarez, Xavier Muñoz-Berbel, Andreu LloberaA microfluidic-controlled optical router enabling the measurement in four individual optical channels using only one light source and one detector.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Spatial presentation of biological molecules to cells by localized diffusive transfer
    by Mary C. Regier on May 10, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2114-2126DOI: 10.1039/C9LC00122K, PaperMary C. Regier, Emily Olszewski, Christoph C. Carter, John D. Aitchison, Alexis Kaushansky, Jennifer Davis, Erwin Berthier, David J. Beebe, Kelly R. StevensWe present a straightforward approach for controlling soluble factor patterning in open in vitro cultures.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic blood vasculature replicas using backside lithography
    by Marianne Fenech on May 6, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2096-2106DOI: 10.1039/C9LC00254E, PaperMarianne Fenech, Vincent Girod, Viviana Claveria, Sebastien Meance, Manouk Abkarian, Benoit CharlotA one-mask microfabrication process to build artificial vascular networks for the analysis of blood flows and hemophysics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Liquid biopsy using the nanotube-CTC-chip: capture of invasive CTCs with high purity using preferential adherence in breast cancer patients
    by Masoud S. Loeian on May 2, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1899-1915DOI: 10.1039/C9LC00274J, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Masoud S. Loeian, Sadegh Mehdi Aghaei, Farzaneh Farhadi, Veeresh Rai, Hong Wei Yang, Mark D. Johnson, Farrukh Aqil, Mounika Mandadi, Shesh N. Rai, Balaji PanchapakesanWe report the development of the nanotube-CTC-chip for isolation of circulating tumor cells of multiple phenotypes from peripheral blood.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Profiling protein–protein interactions of single cancer cells with in situ lysis and co-immunoprecipitation
    by Ji Young Ryu on April 30, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1922-1928DOI: 10.1039/C9LC00139E, CommunicationJi Young Ryu, Jihye Kim, Min Ju Shon, Jiashu Sun, Xingyu Jiang, Wonhee Lee, Tae-Young YoonWe developed a single-cell version of the co-immunoprecipitation (co-IP) analysis that examines the amount and protein–protein interactions of target proteins immunoprecipitated from individual cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Engineering tumor vasculature on an injection-molded plastic array 3D culture (IMPACT) platform
    by Somin Lee on April 29, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2071-2080DOI: 10.1039/C9LC00148D, PaperSomin Lee, Jungeun Lim, James Yu, Jungho Ahn, Younggyun Lee, Noo Li JeonRecent advances in microfluidic organ-on-a-chip technology have enabled the growth of 3D microphysiological systems for diverse biological studies.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Single cell arrays of hematological cancer cells for assessment of lymphocyte cytotoxicity dynamics, serial killing, and extracellular molecules
    by Seong-Eun Kim on April 29, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2009-2018DOI: 10.1039/C9LC00133F, PaperSeong-Eun Kim, HyeMi Kim, Junsang DohA new microwell assays to asses lymphocyte cytotoxicity against hematological cancer cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Using printer ink color to control the behavior of paper microfluidics
    by Joshua Potter on April 25, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2000-2008DOI: 10.1039/C9LC00083F, PaperJoshua Potter, Philip Brisk, William H. GroverDifferent colors of wax inks behave differently in paper microfluidic devices, enabling the development of new color-based paper microfluidic components.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A low-cost, non-invasive phase velocity and length meter and controller for multiphase lab-in-a-tube devices
    by Corwin B. Kerr on April 24, 2019 at 11:00 pm

    Lab Chip, 2019, 19,2107-2113DOI: 10.1039/C9LC00296K, PaperCorwin B. Kerr, Robert W. Epps, Milad AbolhasaniThe non-invasive, optical phase velocity and length meter/controller effectively measures phase length and velocity in real-time with two low-cost photodetectors.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Accessory-free quantitative smartphone imaging of colorimetric paper-based assays
    by Tian Kong on April 23, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1991-1999DOI: 10.1039/C9LC00165D, PaperTian Kong, Jae Bem You, Biao Zhang, Brian Nguyen, Farhang Tarlan, Keith Jarvi, David SintonWe show an accessory-free smartphone-based imaging method applicable to different lighting conditions and correct for differences in phone models.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Direct writing of optical microresonators in a lab-on-a-chip for label-free biosensing
    by L. Kelemen on April 23, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1985-1990DOI: 10.1039/C9LC00174C, PaperL. Kelemen, E. Lepera, B. Horváth, P. Ormos, R. Osellame, R. Martínez VázquezHybrid femtosecond laser fabrication of a glass lab-on-a-chip, with an integrated whispering gallery mode resonator, for label-free biomolecule sensing.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Monitoring transient cell-to-cell interactions in a multi-layered and multi-functional allergy-on-a-chip system
    by Mario Rothbauer on April 22, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1916-1921DOI: 10.1039/C9LC00108E, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Mario Rothbauer, Verena Charwat, Barbara Bachmann, Drago Sticker, Richard Novak, Heinz Wanzenböck, Richard A. Mathies, Peter ErtlMulti-functional LOC for transient allergy monitoring.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • On-the-fly exchangeable microfluidic nozzles for facile production of various monodisperse micromaterials
    by Tom Kamperman on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1977-1984DOI: 10.1039/C9LC00054B, PaperTom Kamperman, Bas van Loo, Melvin Gurian, Sieger Henke, Marcel Karperien, Jeroen LeijtenExchangeable microfluidic nozzles enable the facile production of a wide variety of micromaterials using a single cleanroom-free manufactured microfluidic device.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A microfluidic platform with cell-scale precise temperature control for simultaneous investigation of the osmotic responses of multiple oocytes
    by Zeling Lei on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1929-1940DOI: 10.1039/C9LC00107G, PaperZeling Lei, Dongcheng Xie, Momoh Karmah Mbogba, Zhongrong Chen, Conghui Tian, Lei Xu, Gang ZhaoA microfluidic platform that integrates precise temperature control and multi-oocyte capture is proposed for investigation of oocyte osmotic responses.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Electrocoiling-guided printing of multiscale architectures at single-wavelength resolution
    by Jingmei Li on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1953-1960DOI: 10.1039/C9LC00145J, PaperJingmei Li, Tiantian Kong, Jiazuo Yu, Kit Hang Lee, Yuk Heng Tang, Ka-Wai Kwok, Ji Tae Kim, Ho Cheung ShumAn electrically assisted coiling-jet-based technique is introduced to print nanofibers with programmable patterns. Using this approach, we can swiftly switch filament patterns, enhancing the pattern resolution down to the micrometer range, representing a more than one hundred-fold improvement.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Portable biohybrid odorant sensors using cell-laden collagen micropillars
    by Yusuke Hirata on April 11, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1971-1976DOI: 10.1039/C9LC00131J, PaperYusuke Hirata, Yuya Morimoto, Eunryel Nam, Shoji TakeuchiPortable biohybrid odorant sensors composed of cell-laden collagen pillars and a CMOS imaging sensor achieve quantitative measurement of odorants with high selectivity.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Extraction of nucleic acids from blood: unveiling the potential of active pneumatic pumping in centrifugal microfluidics for integration and automation of sample preparation processes
    by Daniel Brassard on April 7, 2019 at 11:00 pm

    Lab Chip, 2019, 19,1941-1952DOI: 10.1039/C9LC00276F, PaperDaniel Brassard, Matthias Geissler, Marianne Descarreaux, Dominic Tremblay, Jamal Daoud, Liviu Clime, Maxence Mounier, Denis Charlebois, Teodor VeresNAs are extracted from blood using a pneumatic centrifugal platform.The content of this RSS Feed (c) The Royal Society of Chemistry […]

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  • Dual sites fluorescence probe for H<sub>2</sub>S and Hg<sup>2+</sup> with “AIE transformers” function
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Jianting Yang, Binsheng Yang, Guangming Wen, Bin LiuAbstractDual sites fluorescence compound 1 based on 5-bromosalicylaldehyde and 2-benzothiazoleacetonitrile was synthesized. 1 exhibited different aggregation-induced emission (AIE) state in different solution boosting different emission. Different aggregated states gave different chance for H2S and Hg2+ to respond with the formation of new aggregated states. Especially, 1 responded to H2S selectively with an ultrafast rate within 20 s. […]

  • Direct growth of NiO films on Al<sub>2</sub>O<sub>3</sub> ceramics by electrochemical deposition and its excellent H<sub>2</sub>S sensing properties
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Yueying Liu, Fengmin Liu, Jihao Bai, Tianyu Liu, Ziyang Yu, Meng Dai, Linsheng Zhou, Hongtao Wang, Yiqun Zhang, Hui Suo, Geyu LuAbstractNiO thin films were grown directly on the Al2O3 substrates by electrochemical deposition. The H2S gas sensing properties of the thin films were enhanced by Cu doping. The X-ray diffraction revealed the as-prepared films were NiO crystalline phase. The scanning electron microscope showed the film has 1.87 μm thickness and pores of different sizes, more […]

  • Electrospun SnO<sub>2</sub>/PPy nanocomposite for ultra-low ammonia concentration detection at room temperature
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Ajay Beniwal, SunnyAbstractUltra-sensitive, highly selective, fast responsive and extreme low-ppb ammonia (NH3) sensor working at room temperature (RT) has been developed using SnO2/polypyrrole nanocomposite. Porous SnO2 nanofibers having diameter in range ˜70–150 nm were deposited using electrospinning technique, followed by vapor phase polymerization of pyrrole to develop SnO2/polypyrrole (PPy) composite. The mean crystallite size of the composite was calculated using X-ray […]

  • Detection and determination of harmful gases in confined spaces for the Internet of Things based on cataluminescence sensor
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Guolong Shi, Yigang He, Yongxing Zhang, Baiqiang Yin, Farhan AliAbstractGaseous cataluminescence (CTL) sensor instrument was developed for detecting and measuring pernicious gases such as ethyl ether, acetone, n-hexane, chloroform by using aluminum/iron oxides composites. The materials synthesis, apparatus and software, optimal conditions (flow rate, wavelength, temperature and concentration), selectivity and stability were thoroughly studied. The results indicated the CTL sensor instrument could […]

  • Visualization of sulfur mustard in living cells and whole animals with a selective and sensitive turn-on fluorescent probe
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Wenqi Meng, Hao Zhang, Liang Xiao, Xintong Chen, Mingxue Sun, Qingqiang Xu, Yongbing Cao, Kai Xiao, Zhengjiang LiAbstractSulfur mustard is a potent blister agent and one of the most harmful chemical warfare agents. To explore the toxicokinetics and biodistribution of SM, a reliable detection method for monitoring sulfur mustard would be indispensable. We describe the design, synthesis and application of a selective and sensitive turn-on fluorescent probe for sulfur mustard detection. A good linear […]

  • Interface engineered WS<sub>2</sub>/ZnS heterostructures for sensitive and reversible NO<sub>2</sub> room temperature sensing
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Yutong Han, Yang Liu, Chen Su, Shutang Wang, Hong Li, Min Zeng, Nantao Hu, Yanjie Su, Zhihua Zhou, Hao Wei, Zhi YangAbstractThe inherent high surface areas and unique semiconducting properties of two-dimensional (2D) transition metal dichalcogenides (TMDs) make them attractive for the sensing applications. However, the challenges of sensitivity, recoverability and stability still need to be overcome for the rapidly developing fields of TMD based gas sensors. With the general advantages of 2D […]

  • Nanocrystalline LaCoO<sub>3</sub> modified by Ag nanoparticles with improved sensitivity to H<sub>2</sub>S
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Valentina Chumakova, Artem Marikutsa, Marina Rumyantseva, Didier Fasquelle, Alexander GaskovAbstractSemiconductor mixed-metal oxides with perovskite structure are of increasing interest for the application in chemical sensors. LaCoO3 has been extensively studied for its peculiar electronic and magnetic properties, but less is known of the gas sensing mechanisms of this material and its composites. In this work, nanocrystalline LaCoO3 was synthesized by sol-gel method and functionalized by Ag […]

  • Realization of Au-decorated WS<sub>2</sub> nanosheets as low power-consumption and selective gas sensors
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Jae-Hun Kim, Ali Mirzaei, Hyoun Woo Kim, Sang Sub KimAbstractWe introduced a selective and self-heated CO gas sensor based on Au-decorated WS2 nanosheets. Au nanoparticles (NPs) were decorated on WS2 NSs using UV irradiation technique at different irradiation times (1, 15 and 30 s). SiO2 grown on Si was used as substrates and the gas sensors with top electrode configuration were fabricated. Gas sensors were able to work under self-heating mode with an applied voltage of 2 V for […]

  • Solid state electrolyte type gas sensor using stabilized zirconia and MTiO<sub>3</sub> (M: Zn, Co and Ni)-SE for detection of low concentration of SO<sub>2</sub>
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Jing Wang, Ao Liu, Caileng Wang, Rui You, Fangmeng Liu, Siqi Li, Zijie Yang, Junming He, Xu Yan, Peng Sun, Geyu LuAbstractThis paper deals with solid state electrolyte type gas sensors based on mixed potential mechanism using yttria-stabilized zirconia (YSZ) as solid electrolyte and MTiO3 (M: Zn, Co and Ni) as sensing electrodes (SEs) for monitoring very low concentrations of SO2 in atmospheric environments. Among all the devices attached with different SEs, ZnTiO3-SE brought about the highest […]

  • Controllable synthesis of crescent-shaped porous NiO nanoplates for conductometric ethanol gas sensors
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Chen Su, Lu Zhang, Yutong Han, Cong Ren, Xinwei Chen, Jun Hu, Min Zeng, Nantao Hu, Yanjie Su, Zhihua Zhou, Zhi YangAbstractNiO has been widely used as building blocks for gas sensing because of its excellent physicochemical properties. However, the high working temperature of most NiO-based sensors (<200 °C) hinders their further applications. In this work, a novel nanostructure, crescent-shaped porous NiO nanoplates, has been synthesized via hydrothermal approach combining with […]

  • Highly sensitive dual-wavelength fiber ring laser sensor for the low concentration gas detection
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Xianchao Yang, Liangcheng Duan, Haiwei Zhang, Ying Lu, Guangyao Wang, Jianquan YaoAbstractA highly sensitive low concentration gas sensor based on dual-wavelength Erbium-doped fiber ring laser (EDFRL) is designed and demonstrated. The dual-wavelength lasing output is introduced by a tunable Fabry-Perot (F-P) filter and a fiber Bragg grating (FBG) due to the mode competition as they both share a same EDF gain medium. One wavelength at 1530.37 nm serving as the sensing element is inserted by a […]

  • Improvement of sensing properties for SnO<sub>2</sub> gas sensor by tuning of exposed crystal face
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Pil Gyu Choi, Noriya Izu, Naoto Shirahata, Yoshitake MasudaAbstractIn this study, a SnO2 nanosheet was successfully synthesized under moderate conditions without using any additive. The crystal growth direction and the mainly exposed crystal face of the SnO2 nanosheet were investigated. The relationship between the exposed crystal face and the gas sensing properties was also investigated. It was confirmed that the SnO2 nanosheet has a plain size of ˜100 nm and a mainly exposed (101) […]

  • Highly sensitive and selective gas-phase ethanolamine sensor by doping sulfur into nanostructured ZnO
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): He Zhang, Wenqiong Shi, Na Gao, Ruihua Zhao, Md. Maruf Ahmed, Tao Zhang, Jinping Li, Jianping Du, Tewodros AsefaAbstractThe chronic and prolonged exposure to ethanolamine (EA), which is widely used in various commercial and industrial applications, can compromise human health and cause even death. Thus, sensors that can rapidly and efficiently detect EA in air, especially where EA is widely produced or used, is of paramount importance. Herein, we report the synthesis of sulfur-doped, flower-shaped […]

  • Synthesis and characterization of different dopant (Ge, Nd, W)-doped ZnO nanorods and their CO<sub>2</sub> gas sensing applications
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Hakan Çolak, Ercan KaraköseAbstractUndoped and Germanium (Ge), Neodymium (Nd) and Tungsten (W)-doped zinc oxide (ZnO) nanorods in powder form, which are needed for many technological applications, were synthesized. The synthesis procedure was performed through the mechanochemical combustion method using oxalic acid (H2C2O4) as a fuel at 600 °C. The XRD patterns of the ZnO samples were indexed in a hexagonal crystal structure. The solubility limits of Ge, Nd and W dopants in a […]

  • Hydrogen sensing performance of a GaN-based Schottky diode with an H<sub>2</sub>O<sub>2</sub> treatment and electroless plating approach
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): I-Ping Liu, Ching-Hong Chang, Hsin-Hau Lu, Kun-Wei LinAbstract  A new electroless plating (EP)-Pd/GaOx/GaN Schottky diode-type hydrogen sensor is fabricated and comprehensively studied herein. The GaOx dielectric is formed as a result of a proper H2O2 treatment on the GaN surface. In addition, a 20-period sensitization/activation process and an appropriate EP approach of the Pd catalytic layer are employed to facilitate a high-performance metal-semiconductor (M-S) Schottky contact. […]

  • A multichannel single-well sensor array for rapid and visual discrimination of catecholamine neurotransmitters
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Samira Abbasi-Moayed, M. Reza Hormozi-Nezhad, Malik MaazaAbstractIn this study, for rapid identification and discrimination of catecholamine neurotransmitters in the presence of ascorbic acid (AA), a tricolor fluorescence probe has been constructed by integrating three recognition elements including blue carbon dots (bCDs), green CdTe quantum dots (gQDs) and red CdTe quantum dots (rQDs) into a single well. The proposed array exhibited ternary fluorescence emissions at 450, 520 and 630 nm with […]

  • Optical hygrometer using light-sheet skew-ray probed multimode fiber with polyelectrolyte coating
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): George Y. Chen, Xuan Wu, Christophe A. Codemard, Li Yu, Xiaokong Liu, Haolan Xu, Tanya M. Monro, David G. LancasterAbstractThe measurement of humidity provides valuable information to a range of industries. Existing hygrometers lack the combination of high sensitivity/low detection-limit, temperature insensitivity, fast response, high robustness and low cost. We present a new design of humidity sensors based on the combination of a polymer-coated multimode fiber interrogated by a light sheet (i.e. […]

  • A colorimetric sensor array for protein discrimination based on carbon nanodots-induced reversible aggregation of AuNP with GSH as a regulator
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Jingwei Sun, Yuexiang Lu, Liuying He, Jiawei Pang, Fengyi Yang, Yueying LiuAbstractWe have proposed a doubled nanoplasmonic colorimetric sensor array for protein recognition based on car-bon nanodots (CDs)-induced reversible aggregation of gold nanoparticle (AuNP) with GSH as a regulator. It is found that different kinds of CDs can induce the aggregation of AuNP with different degrees and cause different color change. Adding reduced glutathione (GSH) into the CDs/AuNP system can make the AuNP […]

  • A new ratiometric and colorimetric fluorescent Th<sup>4+</sup> probe under extreme acidity and cell imaging
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Bo Liu, Yanhong Tan, Qinghua Hu, Yuyuan Wang, Yu Mao, Peng Tao, Hongqing WangAbstractIt is always a significant challenge to develop a probe for Th4+ in the environment and in vivo under extreme acidity conditions, especially on real-time in the field. Herein, a new Th4+ fluorescent probe N1′,N2′-bis((3-hydroxytetrastyrene-2yl)methylene malonohydrazide (BH-TPE) was designed and studied. It could realize to detect Th4+ in a ratiometric way, which showed relative strong blue fluorescence […]

  • Anion-exchangeable modulated fluorescence strategy for sensitive ascorbic acid detection with luminescent Eu hydroxy double salts nanosunflowers derived from MOFs
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Ali Li, Jie Zhang, Shihao Sun, Erli Ding, Fengjuan Chen, Suisui He, Tianrong Li, Sha Liu, Baodui WangAbstractTo improve the sensitivity and avoid the interference of other substances to the detection of ascorbic acid (AA), luminescent Eu hydroxy double salts (Eu HDSs) sunflowers were developed for fluorescence turn-off detection of AA based on anion-exchangeable strategy. Such Eu HDSs nanoprobe was synthesized by using a leaf-like metal–organic-framework-5 (MOF-5-L) as both precursor and […]

  • Classification of hybrid seeds using near-infrared hyperspectral imaging technology combined with deep learning
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Pengcheng Nie, Jinnuo Zhang, Xuping Feng, Chenliang Yu, Yong HeAbstractThe rapid and efficient selection of eligible hybrid progeny is an important step in cross breeding. However, selecting hybrid offspring that meets specific requirements can be time consuming and expensive. Here, near-infrared hyperspectral imaging technology combined with deep learning was applied to classifying hybrid seeds. The hyperspectral images in the range of 975–1648 nm of a total of 6136 hybrid okra seeds […]

  • Gold nanocluster-based fluorescence turn-off probe for sensing of doxorubicin by photoinduced electron transfer
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Kai-Yuan Huang, Hong-Xing He, Shao-Bin He, Xiang-Ping Zhang, Hua-Ping Peng, Zhen Lin, Hao-Hua Deng, Xing-Hua Xia, Wei ChenAbstractDoxorubicin (DOX), an anthraquinone-based anticancer drug, is effective for the treatment of a variety of human tumors. However, due to its narrow therapeutic window, serum levels need to be closely monitored. Herein, we report the development of a novel fluorescence probe based on gold nanoclusters co-modified with dithiothreitol (DTT) and carboxylated chitosan (CC) […]

  • A smartphone-based colorimetric PET sensor platform with molecular recognition via thermally initiated RAFT-mediated graft copolymerization
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Ceren Kaymaz Kuşçuoğlu, Hasan Güner, Meshude Akbulut Söylemez, Olgun Güven, Murat BarsbayAbstractIn this work, we report a low-cost and easy-to-use molecularly-imprinted colorimetric sensor platform that can sense target analyte with high sensitivity and good selectivity. The platform has been examined for colorimetric detection and quantitation of a model textile dye, basic red 9 (BR9), by employing methacrylic acid (MAA), ethylene glycol dimethacrylate (EGDMA) and […]

  • A fluorescent probe for the dicriminatory detecion of Cys/Hcy, GSH and H<sub>2</sub>S in living cells and zebrafish
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Fengpei Qi, Yun Zhang, Benhua Wang, Wenqiang Chen, Lei Yang, Zhaoguang Yang, Xiangzhi SongAbstractBiothiols such as Cys, Hcy, GSH, and H2S are a critical branch of reactive sulfur species (RSS) and play indispensable roles in human physiological processes. To better understand the intricate and symbiotic networks between these biothiols in physiological processes, single-molecule fluorescent probes to simultaneously distinguish them are highly desirable. Herein, we judiciously conjugated an […]

  • A turn-on fluorescent chemosensor based on aggregation-induced emission for cyanide detection and its bioimaging applications
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Kailun Deng, Lei Wang, Qi Xia, Ruiyuan Liu, Jinqing QuAbstractNumerous efforts are contributed to develop fluorescent sensors for qualitative and quantitative detection of cyanide anion (CN−) as it is inevitably utilized in various fields and detrimental to human health and ecosystem. Herein, a new fluorescent probe TCNT with the feature of aggregation-induced emission was designed and synthesized. Owning a large Stokes shift (˜148 nm) and red fluorescent emission (596 nm), […]

  • New three-component conjugated polymers and their application as super rapid-response fluorescent probe to DNT vapor
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Guangjuan Liu, Alim Abdurahman, Zhaoxia Zhang, Yuting Feng, Feng Li, Ming ZhangAbstractTwo novel three-component conjugated polymers, P1 and P2, composed of fluorene, carbazole and anthracene / pyrene units, were designed and synthesized. After optimizing the ratio of these three components, their spin-coating films were prepared and used to detect nitro explosives in vapor phase, which present almost instantaneous fluorescence quenching (<90%) and high selectivity to 2, 4-dinitrotoluene (DNT) […]

  • DNA-programming multicolor silver nanoclusters for sensitively simultaneous detection of two HIV DNAs
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Rong Zou, Feng Zhang, Chunyan Chen, Changqun CaiAbstractA novel DNA-stabilized silver nanoclusters (AgNCs)-based label-free fluorescent platform for simultaneously detecting two human immunodeficiency virus oligonucleotides (HIV DNAs) was developed. The sensing platform was established based on fluorescence enhancement of guanine (G)-rich and the phenomenon in the process of two silver nanoclusters (AgNCs) forming a nanoclusters dimer. The probe (AgNCs/G) utilized for HIV-1 detection adopted an […]

  • On-site monitoring of thiram via aggregation-induced emission enhancement of gold nanoclusters based on electronic-eye platform
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Xu Zhao, Deshuai Kong, Rui Jin, Hongxia Li, Xu Yan, Fangmeng Liu, Peng Sun, Yuan Gao, Geyu LuAbstractThe rapid and on-site monitoring of thiram is of great significance because the residue of thiram in agriculture has caused great contamination in environment and food, as well as threaten to the human health. Herein, we constructed a fluorometric strategy for on-site monitoring thiram via the aggregation-induced emission enhancement (AIEE) effect of glutathione-capped gold nanoclusters (GSH-AuNCs). […]

  • Multimodal temperature sensing using Zn<sub>2</sub>GeO<sub>4</sub>:Mn<sup>2+</sup> phosphor as highly sensitive luminescent thermometer
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Fengfeng Chi, Bin Jiang, Zhangmei Zhao, Yonghu Chen, Xiantao Wei, Changkui Duan, Min Yin, Wu XuAbstractMotivated from increasing demands of non-contact temperature sensing, here Mn2+ doped Zn2GeO4 (ZGO) phosphor is produced to explore the temperature dependencies of its optical characteristics. Temperature dependencies of emission intensity and luminescence decay lifetime of Mn2+ in the range from 250 K to 420 K are investigated. The maximum relative sensitivities achieved are 4.5% […]

  • Rapid visual identification of nitroaromatics compounds by aggregation-induced enhanced emission fluorescent assays with a Cd(II)-H<sub>3</sub>BTT complex
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Yi Liu, Qi Zhang, Dong Jing, Xuan He, Sheng Cui, Yu LiuAbstractA new type of aggregation induced enhance emission (AIEE) active Cd(II) complex based on novel nitrogen-rich polycyclic ligand 4,5-bis(tetrazol-5-yl)-2H-1,2,3-triazole (H3BTT) and its metal organic gel (MOG) had been synthesized for the first time. The colloid of Cd(II)-H3BTT complex showed obvious AIEE characteristics in binary solvent system of DMF and ethanol, and displayed high sensitivity and selectivity for PA sensing over other […]

  • Green tide biomass templated synthesis of molybdenum oxide nanorods supported on carbon as efficient nanozyme for sensitive glucose colorimetric assay
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Han Ren, Lu Yan, Mingjun Liu, Yanbo Wang, Xuan Liu, Chongyang Liu, Kun Liu, Lingxing Zeng, Aihua LiuAbstractThe nanozymes, alternative for natural enzymes, have become popular in many research fields because they exhibit relatively high activity and stability. Herein, we utilize abundant, renewable ocean green tide (Enteromorpha prolifera, EP) waste as a biotemplate to facilely prepare MoO3 nanorods supported on EP derived carbon (MoO3/C). The as-prepared MoO3/C exhibited excellent peroxidase-like […]

  • Trace detection of impurity phase in preparation of ye'elimite by Eu<sup>3+</sup> fluorescence prober
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Shuxian Wang, Shuxin Liu, Jinpu Zhang, Zhengmao Ye, Xin ChengAbstractYe'elimite (Ca4Al6SO16) is an important component in calcium sulfoaluminate cement. The formation of Ca4Al6SO16 belongs to a complex multiphase reaction, and many aluminate impurity phases might be generated in the reaction process. Trace impurity phase (below 1 wt. %) would seriously influence the hydration mechanism of Ca4Al6SO16, and the overlap of diffraction data between Ca4Al6SO16 and associated impurity phases is not […]

  • An LTCC monolithic microreactor for the synthesis of carbon dots with photoluminescence imaging of the reaction progress
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): M. Berenguel-Alonso, I. Ortiz-Gómez, B. Fernández, P. Couceiro, J. Alonso-Chamarro, L.F. Capitán-Vallvey, A. Salinas-Castillo, M. PuyolAbstractThis work describes the development of a fully integrated Low Temperature Co-fired Ceramic (LTCC) microreactor for the synthesis of carbon dots (CDots). The microreactor integrates fluidics, a heating resistor and an optical window for fluorescence imaging of the reaction progress in a monolithic, all ceramic device, ensuring homogeneous […]

  • A novel ESIPT-ICT-based near-infrared fluorescent probe with large stokes-shift for the highly sensitive, specific, and non-invasive in vivo detection of cysteine
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Lihe Zhao, Xu He, Yibing Huang, Jialiang Li, Yiling Li, Shuo Tao, Ying Sun, Xinghua Wang, Pinyi Ma, Daqian SongAbstractWater solubility, large Stokes-shift, and near-infrared emission are essential properties required for a fluorescent probe used for intracellular detection of the analytes. Herein, we report a new fluorescent probe, BMQA, obtained from the reaction of 2-(2-hydroxyphenyl) benzothiazole, methylquinoline, and acryloyl chloride. By using this probe, it is possible to quantitatively […]

  • Pd@CeO<sub>2</sub>-SnO<sub>2</sub> nanocomposite, a highly selective and sensitive hydrogen peroxide electrochemical sensor
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Ali A. Ensafi, A. Mahmoodi, B. RezaeiAbstractIn this study, Pd@CeO2-SnO2 nanocomposite was synthesized and various methods such as FE-SEM, TEM, EDS, FT-IR, and XRD were used to characterize the nanocomposite. The electrocatalytic behaviour of the nanocomposite was studied for the reduction of H2O2. After optimization of various experimental parameters including pH, scan rate, rotation rate and potential, the calibration curve was plotted for the reduction reaction of the H2O2 at pHs 7.0 and 8.0. At […]

  • Highly sensitive biosensor based on graphene–poly (3-aminobenzoic acid) modified electrodes and porous-hollowed-silver-gold nanoparticle labelling for prostate cancer detection
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Chammari Pothipor, Natta Wiriyakun, Thitirat Putnin, Aroonsri Ngamaroonchote, Jaroon Jakmunee, Kontad Ounnunkad, Rawiwan Laocharoensuk, Noppadol AroonyadetAbstractRecent studies show that electrochemical biosensors offer simple, robust and low-cost solution for point-of-care applications. To meet rigorous requirements of early disease diagnosis and other medical applications, nanomaterials have been investigated to increase sensitivity and selectivity of electrochemical sensors. Herein, we […]

  • Fabrication of a highly sensitive and selective modified electrode for imidacloprid determination based on designed nanocomposite graphene quantum dots/ionic liquid/multiwall carbon nanotubes/polyaniline
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Parisa Nasr-Esfahani, Ali A. Ensafi, Behzad RezaeiAbstractIn this paper, a simple, selective and sensitive electrochemical method was developed for the determination of imidacloprid. To fabricate the modified electrode, at first, a glassy carbon electrode (GCE) was modified with a nanocomposite consist of graphene quantum dots/ionic liquid/multiwall carbon nanotubes (GQDs/IL/MWCNTs). Then, polyaniline (PANI) film was formed on the surface of GQDs/IL/MWCNTs by electropolymerization via cyclic […]

  • Novel electrochemical genosensor for Zika virus based on a poly-(3-amino-4-hydroxybenzoic acid)-modified pencil carbon graphite electrode
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Rafael da Fonseca Alves, Diego Leoni Franco, Marli Tenório Cordeiro, Ernesto Marques de Oliveira, Rosa Amalia Fireman Dutra, Maria Del Pilar Taboada SotomayorAbstractThe Zika virus has recently emerged as a major worldwide threat because it induces microencephaly and other brain damage in babies born to infected mothers. Epidemiological monitoring of infection has been hampered by the lack of reliable tests capable of distinguishing between Zika and other Flavivirus infections, especially […]

  • Novel potential and current type chiral amino acids biosensor based on L/D-handed double helix carbon nanotubes@polypyrrole@Au nanoparticles@L/D-cysteine
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Qi Zhang, Mingxuan Fu, Haijun Lu, Xinyu Fan, Haiyang Wang, Yufan Zhang, Huan WangAbstractNovel chiral amino acids biosensor based on both potential difference and current ratio simultaneously was first established by employing left/right-handed double helix carbon nanotubes (L/D-DHCNT) with chiral structure as substrate material, and by self-assembly anchoring L/D-cysteine (L/D-Cys) on the surface of the left/right-handed double helix carbon nanotubes@Polypyrrole@Au nanoparticles nanocomposites […]

  • Electrochemical aptasensing strategy for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS<sub>2</sub> nanosheets and enzymatic signal amplification
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Yunlei Zhou, Fei Li, Hanwen Wu, Yan Chen, Huanshun Yin, Shiyun Ai, Jun WangAbstractA selective and sensitive electrochemical aptasensing strategy was developed for kanamycin detection based on target-triggered single-strand DNA adsorption on MoS2 nanosheets and enzymatic signal amplification. Firstly, a Y-shape double-stranded DNA (dsDNA) was designed containing probe DNA, assist DNA (labeled with biotin at its 3′-terminal) and aptamer DNA. Then, in the presence of kanamycin, aptamer DNA can […]

  • Determination of lactate levels in biological fluids using a disposable ion-selective potentiometric sensor based on polypyrrole films
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Priscilla Mengarda, Fernando A.L. Dias, João V.C. Peixoto, Raul Osiecki, Márcio F. Bergamini, Luiz H. Marcolino-JuniorAbstractIn this work, we present a lactate-selective potentiometric sensor as simple, low cost and non-enzymatic alternative for application in three different biological fluids. The selectivity of proposed sensor is based on a polypyrrole matrix doped with lactate ions in its structure which occurs during galvanostatic polymerization step. After optimization, the […]

  • A three-dimensional cloth-based microfluidic label-free proximity hybridization-electrochemiluminescence biosensor for ultrasensitive detection of K-ras gene
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Yan Su, Yi Liang, Hongyang Wu, Jun Jiang, Wei Lai, Chunsun ZhangAbstractIn this work, we firstly propose a cloth-based microfluidic DNA biosensor capable of label-free proximity hybridization-electrochemiluminescence (PH-ECL) detection of target DNA (T-DNA). Carbon ink screen-printing is applied to make the cloth-based electrodes that are patterned with wax-screen-printed cloth-based chambers to fabricate a foldable three-dimensional (3-D) cloth-based device for facile fabrication of multi-walled […]

  • One pot synthesis of nanospheres-like trimetallic NiFeCo nanoalloy: A superior electrocatalyst for electrochemical sensing of hydrazine in water bodies
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Muthaiah Annalakshmi, Paramasivam Balasubramanian, Shen-Ming Chen, Tse-Wei ChenAbstractPresent study reports a simple, low-cost, rapid electrochemical sensor for the detection of hydrazine (HY) using trimetallic NiFeCo (NFC) nanospheres as an excellent electrocatalyst. The electrode modifier NFC nanospheres were synthesized through one-pot, facile hydrothermal method. Transmission electron microscopic (TEM) results reveal that the nanoparticles are arranged in a well-defined homogeneous spherical […]

  • High-performance carbon black/molybdenum disulfide nanohybrid sensor for cocoa catechins determination using an extraction-free approach
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Flavio Della Pelle, Daniel Rojas, Annalisa Scroccarello, Michele Del Carlo, Giovanni Ferraro, Carla Di Mattia, Maria Martuscelli, Alberto Escarpa, Dario CompagnoneAbstractIn this work, for the first time, the ability to detect catechins on an effective and regenerable carbon black/molybdenum disulfide nanohybrid screen-printed electrode (SPE-CB/MoS2) is demonstrated. The proposed SPE-CB/MoS2 merges the ability of CB to improve the electrochemical response with the proprieties of MoS2 to totally […]

  • Electrochemical sensing of lead in drinking water using β-cyclodextrin-modified MWCNTs
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Arif Ul Alam, Matiar M.R. Howlader, Nan-Xing Hu, M. Jamal DeenAbstractA simple, facile and low-cost modification of multiwalled carbon nanotubes (MWCNT) with β-cyclodextrin (βCD) through a physical (Phys) and a covalent approach via Steglich esterification (SE) is demonstrated for the detection of lead (Pb). The Pb sensing performance is governed by the amount of βCD present in the MWCNT-βCD matrix and the physical/chemical attachment of βCD with MWCNT. The physically […]

  • Multi-barrel electrodes containing an internal micro-reference for the improved visualization of galvanic corrosion processes in magnesium-based materials using potentiometric scanning electrochemical microscopy
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Dániel Filotás, Bibiana María Fernández-Pérez, Lívia Nagy, Géza Nagy, Ricardo M. SoutoAbstractSimultaneous monitoring of pH and Mg2+ distributions above AZ63 magnesium alloy, either spontaneously corroding or galvanically coupled with iron, was achieved using SECM in the potentiometric operation. By introducing an internal micro-reference electrode in a multi-barrel arrangement of the ion-selective microelectrode used as scanning probe, superior […]

  • Turning toxic cigarette butt waste into the sensor material for the sensitive determination of antihypertensive drug trandolapril from its dosage form and biological samples
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Selva Bilge, Nurgul K. Bakirhan, Yusuf Osman Donar, Ali Sınağ, Sibel A OzkanAbstractThe findings of this study revealed that hydrothermal carbonization (HTC) of filter parts of smoked cigarette butts generates carbonaceous materials that have porosity and high surface area (1012 m2 g−1). This method is relatively eco-friendly because it performed in closed system and under mild conditions. In this study, porous carbon obtained from HTC of smoked cigarette filters was […]

  • Microscopic model for pH sensing mechanism in zinc-based nanowalls
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): A. Scandurra, E. Bruno, G.G. Condorelli, M.G. Grimaldi, S. MirabellaAbstractZinc based nanostructures are very promising material for pH sensing since they allow the realization of low-cost, sustainable, and high sensitivity electrodes. The pH sensitivity reported in literature for different ZnO nanostructures spreads from sub- to super-Nernstian, with the microscopic mechanism behind the H+ detection often unrevealed. In this work we synthesize by hydrothermal process and thermal annealing two […]

  • <em>In situ</em> fabrication of CuO nanowire film for high-sensitive ascorbic acid recognition
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Qiannan You, Tao Liu, Jun Pang, Danfeng Jiang, Zhenyu Chu, Wanqin JinAbstractOne-dimensional metal oxides have been attracting interest as advanced materials for trace target recognition in chemical sensors due to their ultra-high surface area and electrochemical activity. However, the development of a large-scale and controllable fabrication strategy remains a great challenge and has hindered their practical application. In this work, we design a novel thermal oxidation route for obtaining a large […]

  • Ultrasensitive detection of norovirus using a magnetofluoroimmunoassay based on synergic properties of gold/magnetic nanoparticle hybrid nanocomposites and quantum dots
    on January 1, 1970 at 12:00 am

    Publication date: 1 October 2019Source: Sensors and Actuators B: Chemical, Volume 296Author(s): Kenshin Takemura, Jaewook Lee, Tetsuro Suzuki, Thoshimi Hara, Fuyuki Abe, Enoch Y. ParkAbstractNorovirus is the cause of the contagious disease gastroenteritis, and the infection is easy to spread because of the high infectivity of this virus. When the virus infects elderly people and young children, it may progress to severe disease. To prevent this hygienic threat, the development of highly sensitive and rapid detection methods is urgently needed. In this study, we developed a localized surface […]

Microfluidics : nature.com subject feeds Latest news and research from Nature.com on the topic of Microfluidics

Microsystems & Nanoengineering - nature.com technology Microsystems & Nanoengineering is an international open access journal, publishing original articles and reviews covering all aspects of microsystems and nanoengineering from fundamental to applied research.

  • A mass-customizable dermal patch with discrete colorimetric indicators for personalized sweat rate quantification
    by Vaibhav Jain on June 17, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 17 June 2019; doi:10.1038/s41378-019-0067-0Scientists have developed a low-cost wearable skin patch that can monitor the level of perspiration from the human body, and could be used to track hydration levels in athletes, firefighters, and construction workers. Hydration is an important physiological marker, where even small deviations from normal levels can have negative impacts on a human’s cognitive and physical performance and can lead to serious conditions, such as heat exhaustion and stroke. Now, Babak Ziaie, Vaibhav Jain, […]

  • Isolation of intact bacteria from blood by selective cell lysis in a microfluidic porous silica monolith
    by Jung Y. Han on June 17, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 17 June 2019; doi:10.1038/s41378-019-0063-4Scientists have developed a micro-scale device for analyzing bacteria in human blood that could enable the rapid and efficient identification of pathogens at the point-of-care, significantly improving patient outcomes. The presence of bacteria in the bloodstream can lead to serious health problems, including sepsis and infection of other tissues. Early identification of pathogens would greatly enhance the ability of clinicians to provide treatment at the earliest stages of infection, leading to […]

  • Finding the optical properties of plasmonic structures by image processing using a combination of convolutional neural networks and recurrent neural networks
    by Iman Sajedian on June 17, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 17 June 2019; doi:10.1038/s41378-019-0069-yNeural networks can accurately predict the optical properties of plasmonic structures; engineered nanostructures with unique and interesting optical properties. Researchers from South Korea’s Pohang University of Science and Technology (POSTECH), led by Junsuk Rho, linked two machine learning algorithms to collectively extract spatial information from 2D images of structures and use this information to determine their light absorption characteristics. The team first trained their system on […]

  • Reaction injection molding of hydrophilic-in-hydrophobic femtolitre-well arrays
    by Reza Zandi Shafagh on June 3, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 03 June 2019; doi:10.1038/s41378-019-0065-2Researchers from Sweden and Belgium have developed a simplified technique to create microfluidic devices with patterns of modified surface properties. Microfluidic devices, such as the one demonstrated here by a team led by Wouter van der Wijngaart, from KTH Royal Institute of Technology, Sweden, utilize polymer microstructures with hydrophobic and hydrophilic properties to manipulate fluids on a tiny scale. This enables ‘lab-on-a-chip’ experiments with a diverse array of applications. […]

  • Acoustofluidic separation of cells and particles
    by Mengxi Wu on June 3, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 03 June 2019; doi:10.1038/s41378-019-0064-3Research into using sound waves to separate biological particles from fluid moving through tiny channels is rapidly advancing, but more is needed to develop real-life clinical applications. Tony Jun Huang of Duke University in the US and colleagues reviewed the latest studies in the rapidly growing field of ‘acoustofluidic separation’. While progress has been made in using the technology to separate micro-sized objects like cells and bacteria from fluids, few breakthroughs have been […]

  • Inductively coupled, mm-sized, single channel optical neuro-stimulator with intensity enhancer
    by Wasif Khan on June 3, 2019 at 12:00 am

    Microsystems & Nanoengineering, Published online: 03 June 2019; doi:10.1038/s41378-019-0061-6Miniature coils smaller than a grain of rice can improve the comfort of implantable optical devices that target neurons. Optogenetic technology uses pulses of light to turn protein expression in genetically modified neurons on or off. Controlling and collecting data from these devices usually requires bulky cables and batteries, but Wasif Khan from Michigan State University in the United States and colleagues have now developed a completely wireless prototype. The team coupled a microscale […]