Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00676A, PaperSreejith K R, Lena Gorgannezhad, Jing Jin, Chin Hong Ooi, Helen Stratton, Dzung Dao, Nam-Trung NguyenPolymerase chain reaction (PCR) is a popular and well-established DNA amplification technique. Technological and engineering advancements in the field of microfluidics have fuelled the progress of polymerase chain reaction (PCR)...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00243J, PaperAnthony Fan, MD SADDAM HOSSAIN JOY, Taher SaifAxons of neurons are contractile, i.e., they actively maintain a rest tension. However, the spatial origin of this contractility along the axon, and the role of cytoskeleton in generating tension...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00598F, PaperZhen Yuan, Lei Hou, Mallika Bariya, Hnin Yin Yin Nyein, Li-Chia Tai, Wenbo Ji, Lu Li, Ali JaveySweat sensors introduced in recent years have targeted a variety of sweat features and biomarkers for non-invasive health monitoring. Amongst these targets, reliable monitoring of sweat rate is crucial due...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00399A, PaperJae Jung Kim, Felix Ellett, Carina N. Thomas, Fatemeh Jalali, R. Rox Anderson, Daniel Irimia, Adam B. RaffHuman skin models are essential for understanding dermatological diseases and testing new treatment strategies.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00473D, PaperRen LI, Fei Jia, Weikai Zhang, Fanghao Shi, Zhiguo Fang, Hong Zhao, Zhiyuan Hu, Zewen WeiWhole-genome sequencing on circulating tumor cells (CTCs) at single cell level has recently been found helpful for precision medicine, as the oncogenic profiles of single CTC are useful for discovering...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00354A, PaperBeyza Bulutoglu, Camilo Rey Bedon, Young-Bok (Abraham) Kang, Safak MERT, Martin L. Yarmush, Berk UstaNon-alcoholic fatty liver disease (NAFLD) and its progressive form non-alcoholic steatohepatitis (NASH) affect 25% of the world population. NAFLD is predicted to soon become the main cause of liver morbidity...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00508K, PaperSeongho Baek, Jihye Choi, Seok Young Son, Junsuk Kim, Seongjun Hong, Hee Chan Kim, Jong-Hee Chae, Hyomin Lee, Sung Jae KimOver the past several decades, separation and preconcentration methods of (bio)molecules have been actively developed for various biomedical and chemical processes such as disease diagnostics, point of care test and...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00446G, PaperYang Yang, Parinaz Fathi, Glenn Holland, Dipanjan Pan, Nam Sun Wang, Mandy Brigitte EschWe have developed a pumpless cell culture platform that can recirculate small amounts of cell culture medium (400 µL) in a unidirectional and bidirectional flow pattern. The device produces an...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00422J, CommunicationJuhwan Park, Je-Kyun ParkHere, we report the integrated operation of microfluidic pumps and valves only by finger actuation. As the working principle of the finger-actuated microfluidic pumps includes deflection of the poly(dimethylsiloxane) (PDMS)...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00364A, PaperAmid Shakeri, Sara M Imani, Eric Chen, Hanie Yousefi, Raed Shabbir, Tohid Fatanat DidarHere, we present a straightforward technique to create bio-functional microfluidic channels using CO2 plasma to induce both carboxylic and hydroxyl groups onto the channel surface. Consequently, not only does the...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00535H, PaperYong Tae Kim, Sara Bohjanen, Nirveek Bhattacharjee, Albert FolchWe demonstrated a stereolithographically 3D-printed chip for the straightforward injection of hydrogel barriers in microchannels and the facile measurement of molecular diffusivities through these hydrogels.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00538B, PaperAlphonsus H. C. Ng, Songming Peng, Alexander M. Xu, Won Jun Noh, Katherine Guo, Michael T. Bethune, William Chour, Jongchan Choi, Sung Yang, David Baltimore, James R. HeathBarcoded nanoparticles and an integrated DLD and droplet generator device are used to purify and sequence rare antigen-specific T cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00458K, PaperPeter Hsi, Rebecca J. Christianson, Ryan A. Dubay, Charles A. Lissandrello, Jason Fiering, Jenna L. Balestrini, Vishal TandonOur novel device acoustophoretically transfers cells from culture media to electroporation media and then electroporates them using integrated electrodes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00629J, PaperTeresa Cacace, Pasquale Memmolo, Massimiliano Maria Villone, Marco De Corato, Martina Mugnano, melania paturzo, Pietro Ferraro, Pier Luca MaffettoneThe combined use of ultrasound radiation and microfluidics is a promising tool for aiding the development of lab-on-a-chip devices. In this study, we show that the rotation of linear aggregates...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00484J, PaperYang Lin, Yuan Gao, Mengren Wu, Ran Zhou, Daayun Chung, Gabriela Caraveo, Jie XuStick-and-play acoustic micropump and cell traps are built on a plastic film by printing microstructures using two-photon polymerization.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00588A, PaperYilin Wang, Renhua Deng, Lisong Yang, Colin D. BainSchematic of experimental setup for sequential generation of an o/w emulsion by microfluidics and inkjet printing of emulsion droplets.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00315K, PaperAndrew Stephens, Robert Nidetz, Nicolas Mesyngier, Meng Ting Chung, Yujing Song, Jianping Fu, Katsuo KurabayashiSi micromachining processes were used to create a mass-producible immunophenotyping microfluidic device which can isolate and stimulate specific leukocyte populations, enabling measurement of secreted cytokines on-chip via a no-wash immunoassay.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00369J, PaperRuhollah Habibi, Adrian NeildUltrasonic actuation of a packed bed of microbeads enables the entrapment and enrichment of highly-diluted nanoparticles. The approach offers the possibility of future upscaling and high throughput.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00496C, PaperDa Jung Jung, Tae Hoon Shin, Minsuh Kim, Chang Ohk Sung, Se Jin Jang, Gi Seok JeongMicrofluidic devices as translational research tools offers opportunities to aid in reliable medical decision making and to develop customized patient care through predictive modeling of drug sensitivity in patient-derived cancer organoids.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00655A, PaperKai-Jun Che, Yu-Jie Yang, Ya-Li Lin, Yu-Wei Shan, Ya-Hao Ge, Sensen Li, Lujian Chen, Chaoyong James YangThe integration of one more gain media in droplet microlasers with morphology-dependent modes, which can be employed in optofluidic systems as multi-wavelength lasing sources, is highly attractive and demands new...The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00527G, PaperZarmeena Abid, Sophie Strindberg, Madeeha M. Javed, Chiara Mazzoni, Lukas Vaut, Line Hagner Nielsen, Carsten Gundlach, Ritika Singh Petersen, Anette Müllertz, Anja Boisen, Stephan S. KellerWe demonstrate the first complete study on fabrication of biodegradable microcontainers including their evaluation in vitro and in vivo.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00389D, Critical ReviewJuxin Yin, Yuanjie Suo, Zheyu Zou, Jingjing Sun, Shan Zhang, Beng Wang, Yawei Xu, Diane Darland, Julia Xiaojun Zhao, Ying MuIntegrated microfluidic systems with sample preparation and nucleic acid amplification can increase treatment efficiency and improve care.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00140A, PaperJihoon Ko, Jungho Ahn, Suryong Kim, Younggyun Lee, Jungseub Lee, Dohyun Park, Noo Li JeonA standardized microfluidic system based on high-throughput screening for tumor angiogenesis in vitro.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC00997J, CommunicationHyukjin J. Kwon, Seong Kyung Hong, Minsoo Lee, Geunbae LimFor microfluidic applications, we propose a nanochannel for easy fabrication and integration, which is capable of an easy transition between the 3 regimes on demand. We demonstrated an ionic diode and pre-concentration/sensing of DNA.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00618D, PaperPeter Thurgood, Sergio Aguilera Suarez, Sheng Chen, Christopher Gilliam, Elena Pirogova, Aaron R. Jex, Sara Baratchi, Khashayar KhoshmaneshReinforcing a latex balloon with nylon stockings leads to a high pressure self-sufficient pump, which is used for studying the mechanobiology of aortic cells and hydrodynamic capturing of large human monocytes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00454H, CommunicationHaisong Lin, Hannaneh Hojaiji, Shuyu Lin, Christopher Yeung, Yichao Zhao, Bo Wang, Meghana Malige, Yibo Wang, Kimber King, Wenzhuo Yu, Jiawei Tan, Zhaoqing Wang, Xuanbing Cheng, Sam EmaminejadThis work presents a wearable electrofluidic actuation system, which exploits the alternating current electrothermal (ACET) effects to engineer biofluid flow profiles on the body.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00652D, PaperSabiha Tok, Kevin de Haan, Derek Tseng, Can Firat Usanmaz, Hatice Ceylan Koydemir, Aydogan OzcanWe report early detection of E. coli and total coliform bacteria using an automated, colorimetric and fluorometric fiber optics-based device.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00425D, PaperXiangsong Feng, Yukun Ren, Likai Hou, Ye Tao, Tianyi Jiang, Wenying Li, Hongyuan JiangWe present an innovative tri-fluid mixing methodology, potentially applied in multi-step continuous-flow reactions, multicomponent reactions, nanoparticle synthesis, etc.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00428A, PaperMatin Torabinia, Parham Asgari, Udaya Sree Dakarapu, Junha Jeon, Hyejin MoonThis paper presents a microfluidic chemical reaction using an electrowetting-on-dielectric (EWOD) digital microfluidic device.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00502A, PaperHan Sun, Chiu-Wing Chan, Yisu Wang, Xiao Yao, Xuan Mu, Xuedong Lu, Jianhua Zhou, Zongwei Cai, Kangning RenUsing an antimicrobial susceptibility test (AST) as an example, this work demonstrates a practical method to fabricate microfluidic chips entirely from polypropylene (PP) and the benefits for potential commercial use.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2669-2677DOI: 10.1039/C9LC00324J, PaperTakanori Iino, Kazunori Okano, Sang Wook Lee, Takeshi Yamakawa, Hiroki Hagihara, Zhen-Yi Hong, Takanori Maeno, Yusuke Kasai, Shinya Sakuma, Takeshi Hayakawa, Fumihito Arai, Yasuyuki Ozeki, Keisuke Goda, Yoichiroh HosokawaWe demonstrate an on-chip microparticle sorter with an ultrashort switching window using femtosecond laser pulses to overcome the fundamental limitation of the sorting performance described by Poisson statistics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00445A, PaperXing Dong, Junjie Chi, Liuzheng Zheng, Biao Ma, Zhiyang Li, Su Wang, Chao Zhao, Hong LiuWe proposed an integrated device for efficient isolation and ultrasensitive detection of extracellular vesicles for cancer pre-screening.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2741-2749DOI: 10.1039/C9LC00311H, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Crystal M. Han, David Catoe, Sarah A. Munro, Ruba Khnouf, Michael P. Snyder, Juan G. Santiago, Marc L. Salit, Can CenikWe present an on-chip method that achieves simultaneous RNA extraction and size selection, and demonstrate its compatibility with high-throughput sequencing.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2630-2650DOI: 10.1039/C9LC00407F, Critical ReviewChengyu Deng, Lynette B. Naler, Chang LuA review of microfluidic technologies for epigenetic and epigenomic analyses.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00483A, PaperNicole Walters, Luong T. H. Nguyen, Jingjing Zhang, Ajay Shankaran, Eduardo ReáteguiNeutrophil swarming is a complex cell to cell communication process that helps our bodies to combat infections and promote healing damaged tissues. During swarming, neutrophils release extracellular vesicles that help coordinated cell migration.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00418A, PaperHaisong Lin, Yichao Zhao, Shuyu Lin, Bo Wang, Christopher Yeung, Xuanbing Cheng, Zhaoqing Wang, Tianyou Cai, Wenzhuo Yu, Kimber King, Jiawei Tan, Kamyar Salahi, Hannaneh Hojaiji, Sam EmaminejadWe devise a simple, scalable, and low-cost “CAD-to-3D Device” fabrication and integration scheme, which renders 3D and complex microfluidic architectures for wearable biofluid sampling, manipulation, and sensing.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01286E, PaperCheng-Je Lee, Yu-Hsiang HsuVacuum pouch microfluidic system: a new type of lab-on-a-chip device that uses an on-chip vacuum pouch to drive a thin-film micromixer with a wide operation range.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2678-2687DOI: 10.1039/C9LC00370C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Yoshihiro Minagawa, Hiroshi Ueno, Kazuhito V. Tabata, Hiroyuki NojiA compact and simple smartphone-based mobile imaging platform realized swift single influenza virus counting of clinical samples.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2709-2717DOI: 10.1039/C9LC00544G, PaperKuikui Zhang, Shixiao Kong, Yanyan Li, Minghui Lu, Desheng KongAn elastomeric composite material with skin-like mechanical responses and spatially heterogeneous rigidity is developed to accommodate stretchable electronic circuit systems.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2699-2708DOI: 10.1039/C9LC00585D, PaperWen-Bin Lee, Chun-Chih Chien, Huey-Ling You, Feng-Chih Kuo, Mel S. Lee, Gwo-Bin LeeAn integrated microfluidic system capable of automating antimicrobial susceptibility testing against clinical bacteria was developed. Accurate minimum and fractional inhibitory concentrations were determined via a colorimetric assay on-chip.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00542K, PaperAbdullah T. Alsharhan, Ruben Acevedo, Roseanne Warren, Ryan D. SocholWe investigate the use of cyclic olefin polymer to enable in situ direct laser writing of 3D biomimetic structures and microfluidic circuitry.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00267G, PaperArvind Chandrasekaran, Sonya Kouthouridis, Wontae Lee, Nicholas Lin, Zhenwei Ma, Mark J. Turner, John W. Hanrahan, Christopher MoraesMagnetically anchored microboats that can reliably and rapidly create air–liquid interface culture conditions in substrate-stiffness tunable epithelial cell cultures.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2750-2757DOI: 10.1039/C9LC00517J, PaperLei Mou, Ruihua Dong, Binfeng Hu, Zulan Li, Jiangjiang Zhang, Xingyu JiangWe report a hierarchically structured microchip combined with an automated and portable device for dynamic multiplexed immunoassays. Our system can detect multiple biomarkers from pg mL−1 to μg mL−1 spanning a dynamic range of 10 orders of magnitude.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2526-2536DOI: 10.1039/C9LC00081J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pepijn Beekman, Agustin Enciso-Martinez, Hoon Suk Rho, Sidharam Pundlik Pujari, Aufried Lenferink, Han Zuilhof, Leon W. M. M. Terstappen, Cees Otto, Séverine Le GacHere, we report a platform for the specific capture of tdEVs, followed by their in situ characterization using SEM, Raman spectroscopy and AFM, at the single EV level, in terms of size, size distribution and chemical fingerprinting.The content of […]

Lab Chip, 2019, 19,2537-2548DOI: 10.1039/C9LC00400A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Sally A. N. Gowers, Michelle L. Rogers, Marsilea A. Booth, Chi L. Leong, Isabelle C. Samper, Tonghathai Phairatana, Sharon L. Jewell, Clemens Pahl, Anthony J. Strong, Martyn G. BoutelleModular platform providing the building blocks to translate specialised microfluidics from the laboratory to a clinical environment.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2688-2698DOI: 10.1039/C8LC01370E, PaperHirofumi Kobayashi, Cheng Lei, Yi Wu, Chun-Jung Huang, Atsushi Yasumoto, Masahiro Jona, Wenxuan Li, Yunzhao Wu, Yaxiaer Yalikun, Yiyue Jiang, Baoshan Guo, Chia-Wei Sun, Yo Tanaka, Makoto Yamada, Yutaka Yatomi, Keisuke GodaThe drug susceptibility of leukemia cells in whole blood is evaluated by using extreme-throughput imaging flow cytometry with deep learning.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2728-2740DOI: 10.1039/C9LC00431A, PaperZhengyang Ni, Chuhao Yin, Guangyao Xu, Linzhou Xie, Junjie Huang, Shilei Liu, Juan Tu, Xiasheng Guo, Dong ZhangReduced models of SAW-PDMS acoustofluidics need to be reconsidered especially the neglect of shear waves and interface damping.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2718-2727DOI: 10.1039/C9LC00308H, PaperDaniel M. Kainz, Susanna M. Früh, Tobias Hutzenlaub, Roland Zengerle, Nils PaustLateral flow strips (LFSs) are widely used for clinical diagnostics. The restricted flow control is one challenge to the development of quantitative and highly sensitive LFSs. Here, we present a flow control for LFSs using centrifugal microfluidics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2619-2619DOI: 10.1039/C9LC90073J, Correction Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Ying I. Wang, Michael L. ShulerThe content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2512-2525DOI: 10.1039/C9LC00409B, PaperRucha Natu, Monsur Islam, Devin Keck, Rodrigo Martinez-DuarteA highly specific and automated device is desired for selective manipulation of single cells. The device in this work picks cells based on their inherent properties using dielectrophoresis and automatically transfers those at a transfer site.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2486-2499DOI: 10.1039/C9LC00104B, Critical Review Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Joshua D. Bishop, Helen V. Hsieh, David J. Gasperino, Bernhard H. WeiglThis critical review organizes and evaluates state-of-the-art approaches to LFA sensitivity enhancement from a system-level perspective.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2663-2668DOI: 10.1039/C9LC00305C, PaperZhenqing Li, Ruixue Ju, Shinichi Sekine, Dawei Zhang, Songlin Zhuang, Yoshinori YamaguchiA miniaturized device based on integrated continuous flow PCR and electrophoresis microfluidic chip was developed for diagnosis of pathogens. It dispensed with costly external precision syringe pump and can realize rapid DNA amplification and on-site PCR products detection.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2549-2556DOI: 10.1039/C9LC00361D, PaperXuejia Hu, Daoming Zhu, Ming Chen, Keke Chen, Hailiang Liu, Wei Liu, Yi YangPrecise and non-invasive circulating tumor cell isolation based on optical force using homologous erythrocyte binding in a microfluidic system.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2651-2662DOI: 10.1039/C9LC00419J, PaperHaili Zhao, Jin Sha, Xiaofeng Wang, Yongchao Jiang, Tao Chen, Tong Wu, Xin Chen, Huajian Ji, Yang Gao, Linsheng Xie, Yulu MaA novel patterning methodology is reported for fabricating complex polymer brush micropatterns with a spatially controllable 3D nanostructure and chemical composition.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2581-2588DOI: 10.1039/C9LC00256A, PaperOsamu Wakao, Ken Satou, Ayano Nakamura, Polina A. Galkina, Keine Nishiyama, Ken Sumiyoshi, Fumio Kurosawa, Masatoshi Maeki, Akihiko Ishida, Hirofumi Tani, Mikhail A. Proskurnin, Koji Shigemura, Akihide Hibara, Manabu TokeshiA portable fluorescence polarization imaging analyzer was developed for high-throughput fluorescence polarization immunoassay.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2589-2597DOI: 10.1039/C9LC00417C, PaperKevin J. Klunder, Kaylee M. Clark, Cynthia McCord, Kathleen E. Berg, Shelley D. Minteer, Charles S. HenryDemonstration of a simple melt based process to overcome the issue of poorly integrated, low activity and complicated methods of carbon electrode integration into microfluidics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2610-2618DOI: 10.1039/C9LC00301K, PaperMeisam Habibi Matin, Abdolreza Fazeli, Saeed MoghaddamUsing novel microsensors, the formation and evaporation of thin liquid films in microchannels are characterized.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2568-2580DOI: 10.1039/C9LC00285E, PaperMaría A. Ortega, Xiomara Fernández-Garibay, Albert G. Castaño, Francesco De Chiara, Alejandro Hernández-Albors, Jordina Balaguer-Trias, Javier Ramón-AzcónWe present an integrated microdevice capable of simultaneous, in situ cell stimulation and analyte detection. As a proof of concept, the detection of secreted cytokines from an engineered 3D skeletal muscle tissue was measured.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2500-2511DOI: 10.1039/C9LC00469F, PaperTanmay Mathur, Kanwar Abhay Singh, Navaneeth K. R. Pandian, Shu-Huai Tsai, Travis W. Hein, Akhilesh K. Gaharwar, Jonathan M. Flanagan, Abhishek JainOrgan-on-chips made of blood: personalized medicine with microfluidics.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2557-2567DOI: 10.1039/C9LC00341J, PaperLuca Digiacomo, Sara Palchetti, Francesca Giulimondi, Daniela Pozzi, Riccardo Zenezini Chiozzi, Anna Laura Capriotti, Aldo Laganà, Giulio CaraccioloThe use of microfluidic devices may allow standardizing corona formation protocols and comparing data from different laboratories.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Lab Chip, 2019, 19,2598-2609DOI: 10.1039/C9LC00182D, PaperHyukjin Jang, Ashtamurthy S. Pawate, Rohit Bhargava, Paul J. A. KenisIR compatible polymeric microfluidic continuous flow mixer with hyperspectral FT-IR imaging to study fast biomolecular events (10−4 s−1).The content of this RSS Feed (c) The Royal Society of Chemistry […]

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Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Xingxing Jiang, Shuping Liu, Minghui Yang, Avraham RasoolyAbstractBacterial plate count for general assessment of water quality requires lengthy bacterial culturing. We report here a new DNA induced current genosensor for culture independent total bacteria determination. Since the amount of bacterial DNA is correlated to the number of bacteria, the genosensor measures the amount of bacterial DNA to determine bacterial count. The approach relies on bacteria lysis to release DNA which can react […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Mohamed Mokhtar Mohamed, Tarek M. Salama, M. Morsy, Rabab M. Abou Shahba, S.H. MohamedAbstractHerein, we report the synthesis of MoO3−x nanorods via an environmentally solvothermal/annealing route, which involves refluxing of an ethanolic solution of (NH4)6Mo7O24.4H2O for 5 h at 70 °C followed by drying and calcination at 350 °C for 2 h. Graphene oxide (GO) incorporation at 1% ratio into MoO3 increases the oxygen deficient ratio (20.6%) compared to GO free […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Changhui Zhao, Huimin Gong, Gaoqiang Niu, Fei WangAbstractSensitivity and selectivity of metal oxide semiconductor-based gas sensors are two crucial criteria. In this work, a highly sensitive and selective ethanol sensor has been prepared based on Ca-doped In2O3 nanotubes (Ca-In2O3 NTs). The products were synthesized by a simple electrospinning method with subsequent annealing in air. The crystal structure and morphology of as-obtained products are obviously affected by Ca-doping levels […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Oksana V. Monogarova, Aleksandr A. Chaplenko, Kirill V. OskolokAbstractThe original approach was developed and used for screening analysis of more than 40 pharmaceuticals (nonsteroidal analgesics and anti-inflammatory drugs, β-adrenoblockers, secretolytics, fluoroquinolones, metabolic stimulants and others) by digital colorimetry with the use of office flatbed scanner. The proposed technique is based on the simultaneous several colorimetric reactions with different molecular sensors placed […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Chao Wang, Bin Yang, Jinlong Xu, Feng Xia, Jianzhong XiaoAbstractThe influences of sensing electrode morphology, operating temperature and the oxygen content on NH3 sensing properties for the potentiometric gas sensor attached with CeVO4 sensing electrode were studied. With the increase of electrode sintering temperature, CeVO4 grains grow up gradually. The response/recovery time shows a decreasing trend, but the NH3 sensitivity reaches the highest when the sintering temperature reaches […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Jianhua Sun, Lixia Sun, Ning Han, Haomiao Chu, Shouli Bai, Xin Shu, Ruixian Luo, Aifan ChenAbstractThe novel sensing materials of rGO decorated CdS/CdO heterojunction have been synthesized successfully for the first time by a facile one-step hydrothermal method combining with calcination treatment. The structure, morphology, composition, and specific surface of the composite were characterized by XRD, SEM, XPS spectra and BET analysis, respectively. The gas sensing properties to 2 ppm of NO2 were […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Shuzhi Liu, Di Yang, Yijiang Liu, Hua Pan, Hongbiao Chen, Xiaozhong Qu, Huaming LiAbstractIn this work, a novel water-soluble fluorescent probe (BODIPY-P) was designed and synthesized for HClO detection. The probe exhibited ratiometric fluorescence variation with rapid response upon addition of NaClO in deionized water (PBS buffer, pH 7.4) and the change of fluorescence color from red to orange was distinguishable by the naked eyes. The ratio of fluorescence intensity (F567/F629) gradually […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Xiaodan Zhang, Ai Yuan, Xuanxiang Mao, Qiumeng Chen, Yuming HuangAbstractWe report that the Co/Mn oxides nanocomposite, obtained by directly pyrolying cobalt doped Mn-BTC precursor, is a new oxidase mimetic for colorimetric sensing of acid phosphatase (ACP). By tuning the molar ratios of cobalt ions to Mn-BTC (BTC = 1,3,5-benzenetricarboxylate) precursor, four bimetal Co/Mn-BTCs and their derivatives were obtained. These Co/Mn oxides showed 1.4-fold to 2.6-fold higher oxidase-like […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Xuerong Chen, Xiaoman He, Juan Gao, Jizhou Jiang, Xuanfeng Jiang, Can WuAbstractCarbon materials have received intensive attention due to their unique property in the field of electrochemical analysis. As transition metallic heteroatom and nitrogen-codoped carbon (M-N-C) materials commonly exhibit enhanced electrochemical activity for the tuned electronic structure, therefore, fabricating a novel structure of M-N-C material for electrochemical analysis is highly pursued. Herein, an in-situ […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Hao Wan, Ying Gan, Jiadi Sun, Tao Liang, Shuqi Zhou, Ping WangAbstractGas sensors have received extensive attractions due to their critical roles in environmental monitoring, industry manufacture and human safety. This paper for the first time introduces carbon-gold nanocomposites on a reduced graphene oxide based electrochemical gas sensor for high sensitive gas detection. Carbon-gold nanocomposites (CGNs) were synthesized by glucose carbonization and gold nanoparticles deposition using the […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): V. Serafín, B. Arévalo, G. Martínez-García, J. Aznar-Poveda, J.A. Lopez-Pastor, J.F. Beltrán-Sánchez, A.J. Garcia-Sanchez, J. Garcia-Haro, S. Campuzano, P. Yáñez-Sedeño, J.M. PingarrónAbstractThis work describes a new electroanalytical device for the simultaneous and reliable determination of two fertility relevant hormones (luteinizing hormone, LH, and progesterone, P4) in saliva. The device is constructed using a custom […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Július Gajdár, Jiří Barek, Jan FischerAbstractThis study presents an application of a non-toxic mercury meniscus modified silver solid amalgam electrode as a reliable, user-friendly and sensitive sensor for the determination of herbicide difenzoquat as a model pollutant in micro volumes of samples. Difenzoquat gave one cathodic peak at around –1.4 V (vs. Ag/AgCl/3 mol L–1 KCl reference electrode) independent on pH (in the range 8–12). Sharp […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Tingyan Shi, Zuorui Wen, Lijun Ding, Qian Liu, Yingshu Guo, Caifeng Ding, Kun WangAbstractA novel photoelectrochemical (PEC) aptasensor for diclofenac detection, based on visible/near-infrared (vis/NIR) light-responsive vanadyl-phthalocyanine/graphitic carbon nitrid nanosheet (VOPc/CN) nanocomposites, was successfully fabricated. In this work, the first coupling of CN and VOPc with a facile solution–phase method was prepared and applied to PEC sensing. The UV–vis diff ;use […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Tong Bu, Meng Zhang, Xinyu Sun, Yongming Tian, Feier Bai, Pei Jia, Yaowen Bai, Taotao Zhe, Li WangAbstractA simple and novel immunochromatographic assay (ICA) was developed for specific and sensitive determination of ochratoxin A (OTA) employing microorganism (MO) as reducers and carriers. In this work, microorganism loaded gold nanoparticles (MO@AuNPs) composites were synthesized by reacting Yeast/Lactobacillus (LAB) with HAuCl4 via biosorption and subsequent bioreduction. The synthesis […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Pan Guo, Yong Wang, Qianfen ZhuangAbstractA rhodamine B-labelled arginine-rich peptide (RNRHTHLRTRPRK-rhodamine B) was designed as the heparin bioreceptor to construct a highly sensitive and selective fluorescent biosensor for heparin detection. The heparin at picomolar concentration can greatly quenching the fluorescence of the rhodamine B-labelled peptide (RBP) probe in phosphate-buffered solution at pH 5.0. The fluorescence quenching mechanism of the RBP probe by heparin was studied by various […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): William C. Ballance, Inkyu Oh, Yang Lai, Mohamed Elhebeary, Taher Saif, Yuhang Hu, Hyunjoon KongAbstractBiological fouling damages both human health and industry by causing infection, corrosion, structural failure, and drag on marine ships. Current efforts to clean bio-fouled surfaces by externally applying intensive mechanical energy often result in relapsed cell growth. Therefore, this study examines the extent that cell-structure interactions are orchestrated by vibration frequency, […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Huawei Niu, Keke Chen, Jiahui Xu, Xiaofei Zhu, Wenbo Cao, Zhenji Wang, Yong Ye, Yufen ZhaoAbstractThe excessive accumulation of hypochlorite could cause tissue damage and a range of diseases. However, the exact role of hypochlorite in biological activity remains elusive. In many of the reported probes for hypochlorite, DMSO which is an efficient HOCl and •OH scavenger was used as solvent. Besides, no fluorescent probes have been reported to quantify the accumulation of HOCl in living cells […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Florian Patocka, Matthias Schlögl, Christoph Schneidhofer, Nicole Dörr, Michael Schneider, Ulrich SchmidAbstractWe present a novel MEMS sensor which allows the detection of ferrous particles in liquid environments. The device is based on a resonantly excited silicon microcantilever with an integrated planar coil on its surface, which attracts and accumulates ferrous particles on the sensor viamagnetophoresis. The additional mass leads to a shift in resonance frequency of the […]

Publication date: 15 November 2019Source: Sensors and Actuators B: Chemical, Volume 299Author(s): Weiwei Guo, Qilin Zhou, Jie Zhang, Min Fu, Norbert Radacsi, Yanxi LiAbstractIn this work, we report on a novel one-pot hydrothermal synthesis of bismuth (Bi)-doped SnO2/rGO nanocomposites. The composite structures, surface morphologies, chemical compositions, optical properties and crystal defects were characterized by XRD, SEM, TEM, BET, FTIR, Raman, XPS, EPR, PL and UV–vis techniques, and the gas sensing properties to benzene (C6H6) were investigated thoroughly by the […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Wei Liu, Yuelin Xie, Tingxuan Chen, Qixiao Lu, Shafiq Ur Rehman, Ling ZhuAbstractHere, we demonstrate a facile design and simple fabrication of acetone gas sensors based on one-dimensional (1D) porous platinum (Pt)-doped In2O3 nanofiber structure. Be first to try to immerse electrospun polystyrene (PS) nanofibers (NFs) into a precursor solution followed by an annealing process, the as-prepared composite NFs can readily turn into Pt-In2O3 porous NFs. The obtained Pt-In2O3 porous NFs exhibit the […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Sumei Wang, Yichen Guo, Yanjun Xue, Xinzhen Wang, Hongzhi Cui, Jian TianAbstractThe widespread heterophase structure or p-n junction strategies fabricated between different semiconductors are generally used to promote the charge separation in gas-sensing and photocatalysis, which originated from the principle that the composites possess totally different crystalline and energy structures. A vagarious and supreme challenge remained as to whether a junction could be formed between the identical […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Junfeng Chao, Yahui Chen, Shumin Xing, Dongliang Zhang, Wenlei ShenAbstractThe porous and hollow nanostructure materials have drawn consideration attention due to their broader use. Herein, the ZnO/Carbon nanoporous fibers (ZnO/C nanoporous fibers) and ZnO hollow sphere were synthesized simultaneously by using activated carbon fibers (ACF) as an efficiently template. Gas sensors were made based on ZnO/C nanoporous fibers, ZnO hollow sphere, Ag doped ZnO hollow spheres (Ag/ZnO) and Pt decorated ZnO […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Xiaopan Song, Li Li, Xin Chen, Qi Xu, Bao Song, Ziyu Pan, Yining Liu, Fangying Juan, Fan Xu, Bingqiang CaoAbstractChemiresistive gas sensor with high sensitivity, selectivity and fast response for specific target gas has many applications from environmental monitor to internet of things. Herein, a highly sensitive and selective nanostructured triethylamine (TEA) gas sensor is fabricated successfully by designing semiconductor heterostructures consisting of ZnO nanorods and α-Fe2O3 […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Amirmohammad Seif, Alireza Nikfarjam, Hassan Haj ghassemAbstractTiO2/PANI core-shell nanofiber thin film sensors are fabricated by in-situ chemical polymerization on electrospun TiO2 nanofibers, and evaluated for NH3 gas sensing application with UV irradiation at room temperature (25 °C). Fully rutile and 30% anatase-70% rutile mixed phase TiO2 nanofibers are used as n-type core material. PANI as a p-type shell has porous morphology and FE-SEM results reveal that the average thickness […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): R. Alrammouz, J. Podlecki, A. Vena, R. Garcia, P. Abboud, R. Habchi, B. SorliAbstractThis paper reports the fabrication of capacitive humidity sensors by integrating a graphene oxide sensing layer inside paper substrates. Graphene oxide sheets were self-assembled on the papers’ fibers. A comparative study between several sensors with different concentrations of graphene oxide and different processing times in the graphene oxide suspension is reported. Its aim is to optimize the sensing layer […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Nan Zhang, Shengping Ruan, Fengdong Qu, Yanyang Yin, Xin Li, Shanpeng Wen, Samira Adimi, Jingzhi YinAbstractConstructing complex interior nanostructures by metal-organic framework (MOF)-assisted strategy have attracted tremendous attention in the field of material science. Herein, the Co3O4/CoFe2O4 double-shell nanocubes (CCFO DSNCs) were synthesized by a metal–organic framework (MOF) route. The approach included the formation of a zeolite imidazolate framework-67 (ZIF-67)/Co–Fe […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Soyeon Lee, Jin-Woo ParkAbstractWe analyze and explain the reversible humidity-responsive behavior of porous structured luminescent oxygen (O2) sensing films in terms of O2 permeability and optical light scattering. The luminescent O2 sensing films are composed of an O2-sensitive dye within porous polymer matrices, where the porous structure is formed via phase separation between immiscible polystyrene (PS) and polyethylene glycol (PEG). A comparison of the sensing film with a porous polymeric […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Huiling Tai, Zaihua Duan, Zaizhou He, Xian Li, Jianglong Xu, Bohao Liu, Yadong JiangAbstractAs a novel 2D material, Ti3C2Tx has been proved to be promising in the field of room temperature ammonia (NH3) sensors by theoretical calculation and experimental testing. However, its NH3 sensing properties still need to be enhanced. In this short communication, the gas sensor based on TiO2/Ti3C2Tx bilayer film is fabricated for enhancing the NH3 sensing properties of pure Ti3C2Tx. The results show that […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Dawu Lv, Weigang Chen, Wenfeng Shen, Mingyue Peng, Xuesong Zhang, Runfei Wang, Lei Xu, Wei Xu, Weijie Song, Ruiqin TanAbstractHerein we report improved ammonia (NH3) gas sensing properties based on poly (3,4-ethylene-dioxythiophene)-poly(styrenesulfonate) (PEDOT: PSS) thin films with ferric chloride (FeCl3) as additives, which were prepared by inkjet printing the PEDOT: PSS solution and FeCl3 aqueous solution onto the flexible polyimide films in sequence. PEDOT: PSS based gas sensing films with […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Taoping Liu, Wentian Zhang, Lin Ye, Maiken Ueland, Shari L. Forbes, Steven W. SuAbstractThe electronic nose (e-nose) is an olfaction system that consists of an array of chemical sensors and effective machine learning algorithms for the detection of various target odours. Feature extraction and classification methods are of great importance in improving the performance of the e-nose system. In this paper, a novel odour identification method is presented. Firstly, we use the kernel-based system […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Jing Nie, Qiyang Huang, Ning Li, Sunxiang Zheng, Monong Wang, Xiaofeng Meng, Baoxia Mi, Liwei LinAbstractThe two-dimensional (2D) water adsorbing material is used as a sensitive layer for the hydrophilic quartz crystal resonant (QCR) dew point sensor, and its own swelling characteristics determine the accuracy of the sensor's recognition of the saturation status of the water vapor. In order to reveal the mechanism relationship between the swelling characteristics of materials and the measurement […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Zhenhua Tao, Yanwei Li, Bo Zhang, Guang Sun, Min Xiao, Hari Bala, Jianliang Cao, Zhanying Zhang, Yan WangAbstractDeveloping high performance gas sensor for detection of flammable and toxic gases is great significant for environment and health protection. Herein, we reported the selective and quantitative detection of ppb level formaldehyde (HCHO) on a gas sensor based on urchin-like In2O3 hollow spheres (HSs), which were synthesized by calcinating the pre-synthesized urchin-like In(OH)3 HSs at […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Menghan Dun, Jianfeng Tan, Wenhu Tan, Meihui Tang, Xintang HuangAbstractWith the urgent need to improve societal security, semiconductor-based gas sensors have received substantial attention for their efficiency and accuracy in the detection of harmful gases. However, challenging existed to develop sensors that exhibit both high response and rapid response/recovery rates at room temperature. Herein, we present a simple and energy-efficient room-temperature in situ growth strategy to prepare CdS […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Èric Navarrete, Carla Bittencourt, Xavier Noirfalise, Polona Umek, Ernesto González, Frank Güell, Eduard LlobetAbstractA two-step procedure was implemented to obtain tungsten oxide nanowires (WO3) doped with cobalt oxide nanoparticles employing W(CO)6 and the metal-organic precursor Co(acac)2. In the first step, tungsten oxide nanowires were grown at 400 °C using an aerosol assisted chemical vapor deposition system (AA-CVD) and subsequently annealed at 500 ºC for […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Qu Zhou, Wen Zeng, Weigen Chen, Lingna Xu, Rajesh Kumar, Ahmad UmarAbstractThis paper reports the synthesis and characterization of NiO-ZnO nanodisks synthesized through a facile hydrothermal method. The morphological characterizations confirmed the formation of well-defined nanodisks in high density with an average thickness of 60 ± 5 nm. The x-ray diffraction analysis confirmed the well incorporation of the NiO into the matrix of ZnO crystal and the average crystallite […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Jing Wang, Yongqiang Shen, Xian Li, Yi Xia, Cheng YangAbstractThe room-temperature detection of NO2 by metal oxide nanostructures has been a long-term hot topic. The utilization of UV illumination and introducing surface oxygen vacancies (VO) have been demonstrated as effective strategies for enhancing the NO2 sensing performance of metal oxides. Herein, we demonstrated the synergistic effects of UV activation and surface VO on the room-temperature NO2 sensing performance of ZnO nanowires, which […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): P. Cao, Z. Yang, S.T. Navale, S. Han, X. Liu, W. Liu, Y. Lu, F.J. Stadler, D. ZhuAbstractThe development of defined hierarchical transition metal oxide nanostructures has attracted remarkable attention due to their superior chemiresistive gas sensing performances. In the present study, vertically aligned zinc oxide nanorods (ZnO-NRs) were grown by chemical vapor deposition (CVD) and precise decoration with palladium nanoparticles (Pd-NPs) on their surfaces, at different deposition times, was done […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): A. Pauly, J. Brunet, C. Varenne, A.L. NdiayeAbstractHerein we focus on gas sensor responses of both organic macrocycles (MCs) and carbon nanotubes (CNTs) functionalized with MCs (CNTs/MCs) to understand the interaction mechanisms of these materials exposed to aromatics volatile organic compounds (VOCs) such as benzene, toluene and xylene (BTX). The MCs-functionalized CNTs are prepared by non-covalent functionalization using phthalocyanines and porphyrins derivatives. We focus our analysis on the […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Haoyuan Xu, Jianzhong Li, Yu Fu, Yanwen Tian, Zhongdong YangAbstractTin sludge that is produced in an electroplating tin production line is an important tin-containing secondary resource that is mainly composed of SnO2 and a small quantity of sulfur element. In this study, a Pd/PdO/S-SnO2 sensing material for CH4 detection was successfully prepared by green recycling of S-SnO2 from tin sludge in combination with the Pd decoration of S-SnO2 using PdCl2. To intrinsically investigate the sensing […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Lixia Sun, Jianhua Sun, Ning Han, Dankui Liao, Shouli Bai, Xiaojun Yang, Ruixian Luo, Dianqing Li, Aifan ChenAbstractThe development of new materials forever is research front for various application fields, otherwise becomes making bricks without straw. A novel sensing material of rGO decorated W-doped BiVO4 was synthesized for the first time by metal organic decomposition combined with hydrothermal methods for detection of trimethylamine (TEA) vapor. The structure and morphology of material were […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Xu Li, Lei Dai, Zhangxing He, Wei Meng, Yuehua Li, Ling WangAbstractSecond phase enhanced sensing electrodes have attracted special attention with respect to the effectively improved sensing performance for the solid electrolyte type gas sensors. Herein, we present a facile exsolution process conjunction with non-stoichiometry of oxide host (LaFePd0.05O3+δ) to prepare PdO nanoparticles (NPs) decorated sensing electrode for impedancemetric NO2 sensor. The as-prepared composite electrode was […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Zhejia Gu, Simin Zhao, Gaolian Xu, Cang Chen, Yao Wang, Hongchen Gu, Yi Sun, Hong XuAbstractMultiplexed detection of nucleic acids is important for pathogen identification and disease diagnosis. Though real-time quantitative PCR allows for simultaneous amplification of different genes in a single test, the interferences between various primers inevitably cause difficulty in assay design, and pose limitation on multiplexing degree. Conventional solid-phase PCR (SP-PCR) on plenary microarrays can […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): S. Sajed, F. Arefi, M. Kolahdouz, M.A. SadeghiAbstractDetection of various contaminations in drinking water such as heavy metal ions and toxic chemicals is costly, time-consuming and requires an accompanying computing device to capture and analyze the data. Hence, there is an extensive need for a rapid, user-friendly, cost-effective, sensitive and ubiquitous detection technique. Smartphones are an effective means to measure, analyze and share the results. In this work, a gadget was designed and […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Anh Duy Duong Le, Juil Hwang, Mohammad Yusuf, Kang Hyun Park, Sungkyun Park, Jaeyong KimAbstractA polymer-overlaid two-mode microfiber knot resonator (TMM-KR) was designed to measure relative humidity (RH) and temperature simultaneously in a living condition. The device is composed of two main optical features: two-mode microfiber (TMM, slow-varying term) and two-mode knot resonator (TMKR, fast-varying term). After fabricating a TMM by non-adiabatically tapering a conventional single mode fiber […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Ying Liu, Chong-Hua Zhang, Peisheng Zhang, Hong Wang, Jin-Wen Liu, Shenglan Wang, Rongjin Zeng, Shu Chen, Jian ChenAbstractIt is of great value to develop a simple, rapid, label-free and sensitive strategy for tyrosinase activity detection and corresponding inhibitor screening in both biomedical diagnosis and cosmetic industry. However, many recently reported fluorescent assays may suffer from instability to light irradiation, poor water solubility, and complex modification. Herein, a novel […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Sandeep Choudhary, Bhavana Joshi, Gaurav Pandey, Abhijeet JoshiAbstractMilk is a high nutrient value food substance consumed by the entire population in several forms. Spoilage and degradation of milk and its products during transportation, processing and packaging are some of the major losses by dairy industries. The change in milk pH with time is an indicating factor of milk degradation. This research reports a rapid, sensitive and facile fluorescence-based technique to study the time-based milk […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Jaswant Singh, Jyoti Parkash, Varinder Kaur, Raghubir SinghAbstractIn the present work, zinc conjugated Schiff base organic nanoparticles have been fabricated and explored for the quantification and degradation of diethyl chlorophosphate (a common pesticide for green leafy vegetables). Primarily, a Schiff base (SB) was derived by the condensation of 2-hydroxy-4-methoxybenzophenone and 2-aminoethanol and then, it was transformed into organic nanoparticles by reprecipitation method. Further, the […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Huiya Tan, Kaixiang Zhou, Jinwu Yan, Han Sun, Marco Pistolozzi, Mengchao Cui, Lei ZhangAbstractA series of dual-functional red-emitting fluorescent probes were rationally designed, synthesized and evaluated through the introduction of amine chains based on a neutral merocyanine dye (MC-1) for in vivo imaging of beta-amyloid plaques as well as viscosity at cellular level. After optimization, the MC-N derivatives with higher fluorescence quantum yield and rational Log P showed high sensitivity to […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): S. Veerabuthiran, A.K. Razdan, M.K. Jindal, Girraj PrasadAbstractA tunable mid-infrared differential absorption lidar (DIAL) mounted on a mobile platform has been built for long range remote detection of thiodiglycol (TDG) vapor plumes. The IR spectra of TDG have been analyzed from available spectroscopy database and from the laboratory measurement. Based on the analysis, laser wavelengths at 3.190 and 3.300 μm have been selected as λon (strong absorption) and λoff (weak […]

Publication date: 1 November 2019Source: Sensors and Actuators B: Chemical, Volume 298Author(s): Manuel Izquierdo, Alberto Villa-Martínez, Miguel Lastra-Mejías, Regina Aroca-Santos, John C. Cancilla, José S. TorrecillaAbstractA computerized approach to quickly, easily, and efficiently detect discharged sewage of the cheese sector into rivers or reservoirs has been presented in this work. It is based on developing and/or training linear regression, linear multiple regression, and multilayer perceptron-based models using the data obtained from measuring different […]

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Microsystems & Nanoengineering, Published online: 12 August 2019; doi:10.1038/s41378-019-0076-zA hybridization chain reaction permits multiplexed and label-free DNA detection. Nucleic acid detection generally requires a suitable enzyme to amplify the typically low concentration of target nucleic acid sequences, as well as careful control of temperature. However, this limits the ability for multiplexing strategies. Now, a team led by Jonathan M. Cooper at University of Glasgow in the UK report the use of DNA nanoconstructs to enhance the molecular dimensionality of hybridization chain […]

Microsystems & Nanoengineering, Published online: 29 July 2019; doi:10.1038/s41378-019-0075-0A technique that creates uniform films of graphene oxide enables the production of humidity sensors with high accuracy and stability. Technological advancement is fueling a demand for humidity sensors, but reliably producing uniform, high accuracy sensors at a low cost is still a challenge. Jin Xie and his team from China’s Zhejiang University have now developed a surface tension method to create uniform-thickness films of graphene oxide (GO), a humidity sensing material, which can then be […]

Microsystems & Nanoengineering, Published online: 15 July 2019; doi:10.1038/s41378-019-0073-2By measuring cells passing through electrodes, this microfluidics device could soon predict patient response to cancer therapy. Mehdi Javanmard and his team from Rutgers University in the United States developed a device that detects whether a cancer cell is alive based on the shift in its electrical properties as it passes through the device’s spectroscopy detection circuit. The team tested their device using cancer cell samples treated with different concentrations of a targeted […]

Microsystems & Nanoengineering, Published online: 15 July 2019; doi:10.1038/s41378-019-0070-5A new microelectromechanical system (MEMS) using ultrasound stimulation was able to modulate neurons (nerve cells) or brain slices with high spatial resolution. Neuromodulation (altering nerve activity through targeted stimulation) with ultrasound has attracted attention as a non-invasive approach in treating brain diseases. Hitherto, however, ultrasound neuromodulation has suffered from poor spatial resolution. A team headed by Il-Joo Cho of the Korea Institute of Science and Technology, Republic […]

Microsystems & Nanoengineering, Published online: 15 July 2019; doi:10.1038/s41378-019-0071-4An aluminum oxide spacer effectively insulates one electrode from another in a thermionic device. Energy conversion devices such as thermionic and thermophotovoltaic devices require thermal and electrical insulation across two electrodes separated by a small space. However, finding materials that can effectively occupy this gap and minimize parasitic heat flow is challenging. Now, a team led by Igor Bargatin from University of Pennsylvania demonstrate that deposited aluminum oxide spacers can be […]

Microsystems & Nanoengineering, Published online: 01 July 2019; doi:10.1038/s41378-019-0066-1Cosmetic powder acts as an effective component in triboelectric nanogenerators (TENGs) for producing electricity from mechanical movements. The finding, by Zhiyuan Zhu, Zhiwei Xu of Zhejiang University and colleagues in China, is a step towards large-scale production. TENGs generate electricity from small movements, such as finger motions or from raindrops. Friction between their tiny electrodes causes a transfer of electrons that turns into an electrical potential when they separate. More […]