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RSC - Lab Chip latest articles RSC - Lab Chip latest articles

  • Microfluidic On-demand Engineering of Exosomes towards Cancer Immunotherapy
    by Zheng Zhao on April 16, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C8LC01279B, PaperZheng Zhao, Jodi McGill, Pamela Patricia Gamero Kubota, Mei HeExtracellular Vesicles (EVs), particularly exosomes (30-150 nm), are an emerging delivery system in mediating cellular communications, which have been observed for priming immune responses by presenting parent cell signaling proteins...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • On-the-fly Exchangeable Microfluidic Nozzles for Facile Production of Various Monodisperse Micromaterials
    by Tom Kamperman on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00054B, PaperTom Kamperman, Bas van Loo, Melvin Gurian, Sieger Henke, Marcel Karperien, Jeroen LeijtenMicrometer-sized materials are key components for many life science applications including drug delivery, tissue engineering, and (bio)chemical purification methods. Microfluidic manufacturing platforms have advanced the production of micromaterials that are...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A microfluidic platform with cell-scale precise temperature control for simultaneous investigation of the osmotic responses of multiple oocytes
    by Zeling Lei on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00107G, PaperZeling Lei, Dongcheng Xie, Momoh Karmah Mbogba, Zhongrong Chen, Conghui Tian, Lei Xu, Gang ZhaoThe temperature-dependent oocyte membrane permeability plays a significant role in oocyte cryopreservation, such as optimizing the addition/removal of cryoprotective agents and the rate of cooling/rewarming. However, those systems for studying...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Electrocoiling-guided printing of multiscale architectures at single-wavelength resolution
    by Jingmei Li on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00145J, PaperJingmei Li, Tiantian Kong, Jiazuo Yu, Kit Hang LEE, Yuk Heng Tang, ka wai kwok, Ji Tae KIM, Ho Cheung ShumThe rope coiling observed in liquid ink with high viscosity has been exploited in additive printing to fabricate architectures with periodically curled structures and tune their mechanical properties. However, the...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Outstanding Reviewers for Lab on a Chip in 2018
    on April 15, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC90041A, EditorialWe would like to take this opportunity to highlight the Outstanding Reviewers for Lab on a Chip in 2018, as selected by the editorial team for their significant contribution to the journal.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A novel electromagnet-triggered pillar valve and its application in immunoassay on centrifugal platform
    by Yiqi Chen on April 14, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00043G, CommunicationYiqi Chen, Minjie Shen, Yunzeng Zhu, Youchun XuThe lab-on-a-disc is a powerful microfluidic platform that skillfully takes advantages of centrifugal force to controllable drive liquids with the assistance of passive or active valves. However, the passive valves...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Automated detection and sorting of microencapsulation via machine learning
    by Albert Chu on April 14, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01394B, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Albert Chu, Du Nguyen, Sachin S. Talathi, Aaron C. Wilson, Congwang Ye, William L. Smith, Alan D. Kaplan, Eric B. Duoss, Joshua K. Stolaroff, Brian GieraWe automated a traditionally labor-intensive, yet widely-used capsule production system.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Integrated inertial-impedance cytometry for rapid label-free leukocyte isolation and profiling of neutrophil extracellular traps (NETs)
    by Chayakorn Petchakup on April 14, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00250B, PaperChayakorn Petchakup, Hui Min Tay, King Ho Holden Li, Han Wei HouCirculating leukocytes are indispensible components of the immune system, and rapid analysis of their native state or functionalities can help to unravel their pathophysiological roles and identify novel prognostics biomarkers...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • High throughput gene expression profiling of yeast colonies with microgel-culture Drop-seq
    by Leqian Liu on April 14, 2019 at 11:00 pm

    Lab Chip, 2019, Accepted ManuscriptDOI: 10.1039/C9LC00084D, PaperLeqian Liu, Chiraj Dalal, Benjamin Heineike, Adam R. AbateYeasts can be engineered into “living foundries” for non-natural chemical production by reprogramming their genome using a synthetic biology “design-build-test” cycle. While methods for “design” and “build” are scalable and...The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Portable biohybrid odorant sensors using cell-laden collagen micropillars
    by Yusuke Hirata on April 11, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00131J, PaperYusuke Hirata, Yuya Morimoto, Eunryel Nam, Shoji TakeuchiPortable biohybrid odorant sensors composed of cell-laden collagen pillars and a CMOS imaging sensor achieve quantitative measurement of odorants with high selectivity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A numbering-up strategy of hydrodynamic microfluidic filters for continuous-flow high-throughput cell sorting
    by Ryoken Ozawa on April 10, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00053D, PaperRyoken Ozawa, Hideki Iwadate, Hajime Toyoda, Masumi Yamada, Minoru SekiA numbering-up strategy of hydrodynamic filters was presented to dramatically increase the throughput of cell/particle sorting up to ∼15 mL min−1.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • High-throughput electrical position detection of single flowing particles/cells with non-spherical shape
    by Riccardo Reale on April 9, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00071B, PaperRiccardo Reale, Adele De Ninno, Luca Businaro, Paolo Bisegna, Federica CaselliA novel all-electrical approach for cross-sectional position detection of flowing particles and cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A hydrogel-driven microfluidic suction pump with a high flow rate
    by Jaedeok Seo on April 8, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00062C, PaperJaedeok Seo, Cong Wang, Sooyoung Chang, Jungyul Park, Wonjung KimA portable, non-powered, long-term working microfluidic suction pump driven by a superabsorbent polymer was developed.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Hydroporator: a hydrodynamic cell membrane perforator for high-throughput vector-free nanomaterial intracellular delivery and DNA origami biostability evaluation
    by Megan E. Kizer on April 8, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00041K, PaperMegan E. Kizer, Yanxiang Deng, GeoumYoung Kang, Paiyz E. Mikael, Xing Wang, Aram J. ChungWe present a hydrodynamic cell deformation-induced intracellular delivery platform, termed “hydroporator”.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Two-dimensional computational method for generating planar electrode patterns with enhanced volumetric electric fields and its application to continuous dielectrophoretic bacterial capture
    by Chang-Ho Han on April 7, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01288A, PaperChang-Ho Han, Hyun Wook Ha, Jaesung JangNovel method for generating planar electrode patterns with enhanced dielectrophoretic bacterial capture.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Extraction of nucleic acids from blood: unveiling the potential of active pneumatic pumping in centrifugal microfluidics for integration and automation of sample preparation processes
    by Daniel Brassard on April 7, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00276F, PaperDaniel Brassard, Matthias Geissler, Marianne Descarreaux, Dominic Tremblay, Jamal Daoud, Liviu Clime, Maxence Mounier, Denis Charlebois, Teodor VeresNAs are extracted from blood using a pneumatic centrifugal platform.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Droplet-based single cell RNAseq tools: a practical guide
    by Robert Salomon on April 7, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01239C, PerspectiveRobert Salomon, Dominik Kaczorowski, Fatima Valdes-Mora, Robert E. Nordon, Adrian Neild, Nona Farbehi, Nenad Bartonicek, David Gallego-OrtegaA step-by-step guide for droplet-based single cell RNAseq experiments, practical considerations and technical notes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Digestion-on-a-chip: a continuous-flow modular microsystem recreating enzymatic digestion in the gastrointestinal tract
    by Pim de Haan on April 4, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01080C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Pim de Haan, Margaryta A. Ianovska, Klaus Mathwig, Glenn A. A. van Lieshout, Vassilis Triantis, Hans Bouwmeester, Elisabeth VerpoorteA three-compartment, miniaturized system to pretreat samples with artificial saliva, gastric juice, duodenal juice and bile for gut-on-a-chip applications.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The […]

  • Smartphone-app based point-of-care testing for myocardial infarction biomarker cTnI using an autonomous capillary microfluidic chip with self-aligned on-chip focusing (SOF) lenses
    by Chao Liang on April 3, 2019 at 11:00 pm

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00259F, PaperChao Liang, Yuanchang Liu, Aiying Niu, Chong Liu, Jingmin Li, Dianxiu NingWe present a smartphone-app platform for point-of-care testing of cTnI, which features the self-aligned on-chip focusing (SOF) lenses for enhancing the fluorescence intensity.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Simplified Drop-seq workflow with minimized bead loss using a bead capture and processing microfluidic chip
    by Marjan Biočanin on March 28, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00014C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Marjan Biočanin, Johannes Bues, Riccardo Dainese, Esther Amstad, Bart DeplanckeSingle-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of […]

  • Gel-on-a-chip: continuous, velocity-dependent DNA separation using nanoscale lateral displacement
    by Benjamin H. Wunsch on March 28, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01408F, PaperBenjamin H. Wunsch, Sung-Cheol Kim, Stacey M. Gifford, Yann Astier, Chao Wang, Robert L. Bruce, Jyotica V. Patel, Elizabeth A. Duch, Simon Dawes, Gustavo Stolovitzky, Joshua T. SmithWe studied the dsDNA trajectories being advected while diffusing in a pressure driven flow in a nanoDLD array.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A microfluidic approach for probing hydrodynamic effects in barite scale formation
    by Ricardo D. Sosa on March 27, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00061E, PaperRicardo D. Sosa, Xi Geng, Michael A. Reynolds, Jeffrey D. Rimer, Jacinta C. ConradWe present a microfluidics platform for characterizing the growth and dissolution of barite, a common component of mineral scale, in dynamic flow conditions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Traction microscopy with integrated microfluidics: responses of the multi-cellular island to gradients of HGF
    by Hwanseok Jang on March 27, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00173E, PaperHwanseok Jang, Jongseong Kim, Jennifer H. Shin, Jeffrey J. Fredberg, Chan Young Park, Yongdoo ParkMicrofluidic system integrated with cell collectives and traction microscopy demonstrates that collective cell migration plays a central role in development, regeneration, and metastasis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Femtoliter nanofluidic valve utilizing glass deformation
    by Yutaka Kazoe on March 26, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C8LC01340C, PaperYutaka Kazoe, Yuriy Pihosh, Hitomi Takahashi, Takeshi Ohyama, Hiroki Sano, Kyojiro Morikawa, Kazuma Mawatari, Takehiko KitamoriA femtoliter nanochannel open/close valve utilizing tiny glass deformation, which will enable highly-integrated glass nanofluidic devices, was proposed and demonstrated.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Generating digital drug cocktails via optical manipulation of drug-containing particles and photo-patterning of hydrogels
    by Yi-Sin Chen on March 26, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00189A, PaperYi-Sin Chen, Ko-Chin Chung, Wen-Yen Huang, Wen-Bin Lee, Chien-Yu Fu, Chih-Hung Wang, Gwo-Bin LeeAn integrated microfluidic system combining 1) ODEP for manipulation of drug-containing particles and 2) UV “direct writing” capable of patterning hydrogels was established for automatic formulation of customized digital drug cocktails.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Immature dendritic cells navigate microscopic mazes to find tumor cells
    by Eujin Um on March 26, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00150F, PaperEujin Um, Jung Min Oh, Juhee Park, Taegeun Song, Tae-Eon Kim, Yongjun Choi, Changsik Shin, Diana Kolygina, Jae-Hyung Jeon, Bartosz A. Grzybowski, Yoon-Kyoung ChoImposing physical confinements in the migration tracks of dendritic cells reveals different migratory behaviors towards cancer vs. normal cells.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • High-throughput acoustofluidic fabrication of tumor spheroids
    by Bin Chen on March 25, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00135B, PaperBin Chen, Yue Wu, Zheng Ao, Hongwei Cai, Asael Nunez, Yunhua Liu, John Foley, Kenneth Nephew, Xiongbin Lu, Feng GuoThree-dimensional (3D) culture of multicellular spheroids, offering a desirable biomimetic microenvironment, is appropriate for recapitulating tissue cellular adhesive complexity and revealing a more realistic drug response.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • High-throughput single-particle detections using a dual-height-channel-integrated pore
    by Wataru Tonomura on March 25, 2019 at 12:00 am

    Lab Chip, 2019, 19,1352-1358DOI: 10.1039/C8LC01371C, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Wataru Tonomura, Makusu Tsutsui, Akihide Arima, Kazumichi Yokota, Masateru Taniguchi, Takashi Washio, Tomoji KawaiWe report a proof-of-principle demonstration of particle concentration to achieve high-throughput resistive pulse detections of bacteria using a microfluidic-channel-integrated micropore.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Droplet CAR-Wash: continuous picoliter-scale immunocapture and washing
    by Steven R. Doonan on March 25, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00125E, PaperSteven R. Doonan, Melissa Lin, Ryan C. BaileyThe CAR-Wash provides >100-fold dilution with >98% magnetic bead recovery for washing picoliter-scale droplets at 500 Hz.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Simultaneous detection of multiple NT-proBNP clinical samples utilizing an aptamer-based sandwich assay on an integrated microfluidic system
    by Anirban Sinha on March 25, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00115H, PaperAnirban Sinha, Priya Gopinathan, Yi-Da Chung, Shu-Chu Shiesh, Gwo-Bin LeeAn integrated microfluidic platform was developed for the simultaneous detection of NT-proBNP, a widely studied biomarker for heart failure diagnosis, in up to six clinical samples within 25 min by using a novel aptamer-based sandwich assay.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Waveguide-based chemo- and biosensors: complex emulsions for the detection of caffeine and proteins
    by Lukas Zeininger on March 21, 2019 at 12:00 am

    Lab Chip, 2019, 19,1327-1331DOI: 10.1039/C9LC00070D, Communication Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Lukas Zeininger, Elisabeth Weyandt, Suchol Savagatrup, Kent S. Harvey, Qifan Zhang, Yanchuan Zhao, Timothy M. SwagerEmulsion waveguides: a new modular sensing approach in which complex emulsions serve as efficient transducers in optical evanescent field-based waveguide sensors is reported.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • MEMS-based condensation particle growth chip for optically measuring the airborne nanoparticle concentration
    by Hong-Beom Kwon on March 21, 2019 at 12:00 am

    Lab Chip, 2019, 19,1471-1483DOI: 10.1039/C9LC00035F, PaperHong-Beom Kwon, Seong-Jae Yoo, Ui-Seon Hong, Kyungtae Kim, Jangseop Han, Min-Ki Kim, Dong-Hyun Kang, Jungho Hwang, Yong-Jun KimWe present a low-cost and compact airborne nanoparticle sensor that can count individual nanoparticles in real-time.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic centrifugation assisted precipitation based DNA quantification
    by I. Banerjee on March 20, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00196D, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.I. Banerjee, S. G. Aralaguppe, N. Lapins, W. Zhang, A. Kazemzadeh, A. Sönnerborg, U. Neogi, A. RussomA microfluidic centrifugation assisted precipitation method for rapid DNA visualization and quantification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Semi-automated on-demand control of individual droplets with a sample application to a drug screening assay
    by Marie Hébert on March 19, 2019 at 12:00 am

    Lab Chip, 2019, 19,1490-1501DOI: 10.1039/C9LC00128J, PaperMarie Hébert, Matthew Courtney, Carolyn L. RenAutomated control of individual droplets in microfluidic channels offers tremendous potential for applications requiring high accuracy and minimal user involvement.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Laser printing-enabled direct creation of cellular heterogeneity in lab-on-a-chip devices
    by Ruitong Xiong on March 19, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00117D, PaperRuitong Xiong, Wenxuan Chai, Yong HuangLaser-induced forward transfer for printing of cellular heterogeneity in organ-on-a-chip devices.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • AC electrokinetic biased deterministic lateral displacement for tunable particle separation
    by Victor Calero on March 19, 2019 at 12:00 am

    Lab Chip, 2019, 19,1386-1396DOI: 10.1039/C8LC01416G, PaperVictor Calero, Pablo Garcia-Sanchez, Carlos Honrado, Antonio Ramos, Hywel MorganWe describe a novel particle separation technique that combines deterministic lateral displacement (DLD) with orthogonal electrokinetic forces to separate particles below the critical diameter.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A high-speed, high-performance, microfabricated comprehensive two-dimensional gas chromatograph
    by Joshua J. Whiting on March 18, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00027E, PaperJoshua J. Whiting, Edward Myers, Ronald P. Manginell, Mathew W. Moorman, John Anderson, Cory S. Fix, Cody Washburn, Al Staton, Daniel Porter, Darin Graf, David R. Wheeler, Stephen Howell, John Richards, Haley Monteith, Komandoor E. Achyuthan, Michael Roukes, Robert J. SimonsonA microfabricated ultrafast GC×GC system, coupled with highly sensitive, low-power NEMS resonators, with handheld form factor for civilian, military, and space applications.To cite this article before page numbers are assigned, use the DOI form of […]

  • Asymmetric confinement for defining outgrowth directionality
    by Paul M. Holloway on March 18, 2019 at 12:00 am

    Lab Chip, 2019, 19,1484-1489DOI: 10.1039/C9LC00078J, PaperPaul M. Holloway, Grace I. Hallinan, Manjunath Hegde, Simon I. R. Lane, Katrin Deinhardt, Jonathan WestEdge-guidance and turning angle principles were used to design asymmetric microstructures to affect unidirectional outgrowth bias and provide new insights into pathfinding.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Hydrodynamic shuttling for deterministic high-efficiency multiple single-cell capture in a microfluidic chip
    by Cheng-Kun He on March 15, 2019 at 12:00 am

    Lab Chip, 2019, 19,1370-1377DOI: 10.1039/C9LC00036D, PaperCheng-Kun He, Ya-Wen Chen, Ssu-Han Wang, Chia-Hsien HsuA new microfluidics technique for high-efficiency paring and analyzing multiple single cells can facilitate cellular heterogeneity studies important for biological and biomedical research.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Multiparameter antibiotic resistance detection based on hydrodynamic trapping of individual E. coli
    by Giampaolo Pitruzzello on March 14, 2019 at 12:00 am

    Lab Chip, 2019, 19,1417-1426DOI: 10.1039/C8LC01397G, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Giampaolo Pitruzzello, Stephen Thorpe, Steven Johnson, Adrian Evans, Hermes Gadêlha, Thomas F. KraussWe present a single-bacteria hydrodynamic trapping platform to detect antibiotic susceptibility and resistance by simultaneously monitoring motility and morphology of individual E. coli.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Passive sweat collection and colorimetric analysis of biomarkers relevant to kidney disorders using a soft microfluidic system
    by Yi Zhang on March 12, 2019 at 12:00 am

    Lab Chip, 2019, Advance ArticleDOI: 10.1039/C9LC00103D, PaperYi Zhang, Hexia Guo, Sung Bong Kim, Yixin Wu, Diana Ostojich, Sook Hyeon Park, Xueju Wang, Zhengyan Weng, Rui Li, Amay J. Bandodkar, Yurina Sekine, Jungil Choi, Shuai Xu, Susan Quaggin, Roozbeh Ghaffari, John A. RogersPassive sweat collection and colorimetric analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A smartphone fluorescence imaging-based mobile biosensing system integrated with a passive fluidic control cartridge for minimal user intervention and high accuracy
    by Won-Il Lee on March 12, 2019 at 12:00 am

    Lab Chip, 2019, 19,1502-1511DOI: 10.1039/C8LC01344F, PaperWon-Il Lee, Younghyeon Park, Jaemin Park, Sajal Shrivastava, Young-Min Son, Hak-Jong Choi, Jaelin Lee, Byeungwoo Jeon, Heon Lee, Nae-Eung LeeA biosensor with minimal user interventions and high accuracy.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Overcoming transport limitations in miniaturized electrophoretic delivery devices
    by Maria Seitanidou on March 11, 2019 at 12:00 am

    Lab Chip, 2019, 19,1427-1435DOI: 10.1039/C9LC00038K, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Maria Seitanidou, Klas Tybrandt, Magnus Berggren, Daniel T. SimonCombining experimental and theoretical approach, we demonstrate practical solutions to limiting currents in capillary-based electrophoretic delivery devices.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic device for expedited tumor growth towards drug evaluation
    by Christopher George Uhl on March 8, 2019 at 12:00 am

    Lab Chip, 2019, 19,1458-1470DOI: 10.1039/C8LC01250D, PaperChristopher George Uhl, Yaling LiuExpedited cancer growth technique to generate cancer populations for therapeutic screening within 3 days utilizing media flow and few cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Sorting by interfacial tension (SIFT): label-free selection of live cells based on single-cell metabolism
    by Ching W. Pan on March 8, 2019 at 12:00 am

    Lab Chip, 2019, 19,1344-1351DOI: 10.1039/C8LC01328D, PaperChing W. Pan, Daniel G. Horvath, Samuel Braza, Trevor Moore, Annabella Lynch, Cameron Feit, Paul AbbyadA new label-free and passive microfluidic technique to select cells based on single-cell glycolytic activity. The method has broad applicability and we demonstrate here single-cell droplet encapsulation and selection of live cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Non-contact monitoring of extra-cellular field potentials with a multi-electrode array
    by Tal Sharf on March 8, 2019 at 12:00 am

    Lab Chip, 2019, 19,1448-1457DOI: 10.1039/C8LC00984H, PaperTal Sharf, Paul K. Hansma, Mukund A. Hari, Kenneth S. KosikA single set of electrical sensors can probe the activity of electrogenic cells grown on disposable coverslips without degrading its performance.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Development of a multicellular pancreatic tumor microenvironment system using patient-derived tumor cells
    by Daniel Gioeli on March 6, 2019 at 12:00 am

    Lab Chip, 2019, 19,1193-1204DOI: 10.1039/C8LC00755A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Daniel Gioeli, Chelsi J. Snow, Michael B. Simmers, Stephen A. Hoang, Robert A. Figler, J. Ashe Allende, Devin G. Roller, J. Thomas Parsons, Julia D. Wulfkuhle, Emanuel F. Petricoin, Todd W. Bauer, Brian R. WamhoffThe development of drugs to treat cancer is hampered by the inefficiency of translating pre-clinical in vitro monoculture and mouse studies into clinical benefit.The content of this RSS Feed (c) The Royal […]

  • Label-free separation of leukocyte subpopulations using high throughput multiplex acoustophoresis
    by Anke Urbansky on March 6, 2019 at 12:00 am

    Lab Chip, 2019, 19,1406-1416DOI: 10.1039/C9LC00181F, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Anke Urbansky, Franziska Olm, Stefan Scheding, Thomas Laurell, Andreas LenshofImplementing a new designed cooling system for rigorous temperature control and minimal acoustic energy losses allows high-throughput multiplex acoustophoresis.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Microfluidic arenas for war games between neutrophils and microbes
    by Felix Ellett on March 5, 2019 at 12:00 am

    Lab Chip, 2019, 19,1205-1216DOI: 10.1039/C8LC01263F, PaperFelix Ellett, Fatemeh Jalali, Anika L. Marand, Julianne Jorgensen, Baris R. Mutlu, Jarone Lee, Adam B. Raff, Daniel IrimiaNanoliter-scale microfluidic arenas for imaging war games between human neutrophils and microbes at cellular resolution.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A miniaturized push–pull-perfusion probe for few-second sampling of neurotransmitters in the mouse brain
    by Floris T. G. van den Brink on March 5, 2019 at 12:00 am

    Lab Chip, 2019, 19,1332-1343DOI: 10.1039/C8LC01137K, PaperFloris T. G. van den Brink, Thas Phisonkunkasem, Ashish Asthana, Johan G. Bomer, Arn M. J. M. van den Maagdenberg, Else A. Tolner, Mathieu OdijkMeasuring neurotransmitters in the brain of living animals is a challenging task, especially when detailed information at high temporal resolution is required.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Extracellular vesicles as cancer liquid biopsies: from discovery, validation, to clinical application
    by Zhen Zhao on March 5, 2019 at 12:00 am

    Lab Chip, 2019, 19,1114-1140DOI: 10.1039/C8LC01123K, Tutorial ReviewZhen Zhao, Jia Fan, Yen-Michael S. Hsu, Christopher J. Lyon, Bo Ning, Tony Y. HuSubstantial research has been devoted to elucidate the roles that extracellular vesicles (EVs) play in the regulation of both normal and pathological processes, and multiple studies have demonstrated their potential as a source of cancer biomarkers.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Quantifying the pH shift induced by selective anodic electrochemical reactions in the ion concentration polarization phenomenon
    by Wonseok Kim on March 4, 2019 at 12:00 am

    Lab Chip, 2019, 19,1359-1369DOI: 10.1039/C8LC01363B, PaperWonseok Kim, Jeewhan Oh, Soonhyun Kwon, Kihong Kim, Sung Jae KimWe demonstrated how preconcentration and purification efficiencies developed by ICP (Ion Concentration Polarization) were governed by electrochemical reactions using two types of electrode configurations; large exposed electrode area (LEEA) and small exposed electrode area (SEEA).The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Tailoring surface acoustic wave atomisation for cryo-electron microscopy sample preparation
    by Dariush Ashtiani on March 4, 2019 at 12:00 am

    Lab Chip, 2019, 19,1378-1385DOI: 10.1039/C8LC01347K, PaperDariush Ashtiani, Alex de Marco, Adrian NeildSurface acoustic wave (SAW) atomisation is investigated in the context of cryo electron microscopy grid preparation. Here, the primary requirements are a reproducible and narrow plume of droplets delivering a low fluid flow rate.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Array based real-time measurement of fluid viscosities and mass-densities to monitor biological filament formation
    by Paolo Oliva on March 4, 2019 at 12:00 am

    Lab Chip, 2019, 19,1305-1314DOI: 10.1039/C8LC01343H, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Paolo Oliva, Benjamin Andreas Bircher, Cora-Ann Schoenenberger, Thomas BraunA membrane-based resonator detecting filament formation of biological samples in a label- and functionalization-free manner.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Long-term hydrolytically stable bond formation for future membrane-based deep ocean microfluidic chemical sensors
    by M. Tweedie on March 1, 2019 at 12:00 am

    Lab Chip, 2019, 19,1287-1295DOI: 10.1039/C9LC00123A, PaperM. Tweedie, D. Sun, B. Ward, P. D. MaguireFuture ocean profiling of dissolved inorganic carbon and other analytes will require miniaturised chemical analysis systems based on sealed gas membranes between two fluid channels.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A foldable isothermal amplification microdevice for fuchsin-based colorimetric detection of multiple foodborne pathogens
    by Thi Ngoc Diep Trinh on February 27, 2019 at 12:00 am

    Lab Chip, 2019, 19,1397-1405DOI: 10.1039/C8LC01389F, PaperThi Ngoc Diep Trinh, Nae Yoon LeeLoop-mediated isothermal amplification combined with fuchsin-based colorimetric detection in a foldable microdevice for rapid and multiplex identification of foodborne pathogens.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche
    by C. Ryan Oliver on February 27, 2019 at 12:00 am

    Lab Chip, 2019, 19,1162-1173DOI: 10.1039/C8LC01387J, PaperC. Ryan Oliver, Megan A. Altemus, Trisha M. Westerhof, Hannah Cheriyan, Xu Cheng, Michelle Dziubinski, Zhifen Wu, Joel Yates, Aki Morikawa, Jason Heth, Maria G. Castro, Brendan M. Leung, Shuichi Takayama, Sofia D. MerajverBrain metastases are the most lethal complication of advanced cancer; therefore, it is critical to identify when a tumor has the potential to metastasize to the brain.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Luminescence thermometry for in situ temperature measurements in microfluidic devices
    by Robin G. Geitenbeek on February 25, 2019 at 12:00 am

    Lab Chip, 2019, 19,1236-1246DOI: 10.1039/C8LC01292J, PaperRobin G. Geitenbeek, Jeroen C. Vollenbroek, Hannah M. H. Weijgertze, Corentin B. M. Tregouet, Anne-Eva Nieuwelink, Chris L. Kennedy, Bert M. Weckhuysen, Detlef Lohse, Alfons van Blaaderen, Albert van den Berg, Mathieu Odijk, Andries MeijerinkIn this work we present 3 showcases that luminescence thermometry is a promising and versatile technique for temperature monitoring in various microfluidic devices.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • An electric-field-dependent drop selector
    by Jinlong Yang on February 25, 2019 at 12:00 am

    Lab Chip, 2019, 19,1296-1304DOI: 10.1039/C8LC01403E, PaperJinlong Yang, Dehui Wang, Hailong Liu, Linxian Li, Longquan Chen, Hong-Ren Jiang, Xu DengWe have designed a superhydrophobic-coated chip to manipulate the static and dynamic behaviors of a drop using dielectrowetting.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A diffusion-based microfluidic device for single-cell RNA-seq
    by Mimosa Sarma on February 22, 2019 at 12:00 am

    Lab Chip, 2019, 19,1247-1256DOI: 10.1039/C8LC00967H, PaperMimosa Sarma, Jiyoung Lee, Sai Ma, Song Li, Chang LuScalable microfluidic devices containing reaction and loading chambers were developed to conduct single-cell transcriptomic studies.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • An integrated microfluidic system for rapid detection and multiple subtyping of influenza A viruses by using glycan-coated magnetic beads and RT-PCR
    by Kao-Mai Shen on February 22, 2019 at 12:00 am

    Lab Chip, 2019, 19,1277-1286DOI: 10.1039/C8LC01369A, PaperKao-Mai Shen, Narayana Murthy Sabbavarapu, Chien-Yu Fu, Jia-Tsrong Jan, Jen-Ren Wang, Shang-Cheng Hung, Gwo-Bin LeeA microfluidic chip featuring HA × NA arrayed reaction chambers for RT-PCR was developed for diagnosis and subtyping of influenza A viruses.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Intensity-modulated nanoplasmonic interferometric sensor for MMP-9 detection
    by Yifeng Qian on February 22, 2019 at 12:00 am

    Lab Chip, 2019, 19,1267-1276DOI: 10.1039/C8LC01391H, PaperYifeng Qian, Xie Zeng, Yongkang Gao, Hang Li, Sushil Kumar, Qiaoqiang Gan, Xuanhong Cheng, Filbert J. BartoliNanoplasmonic interferometric imagers successfully detect MMP-9 in supernatant, demonstrating the potential for multiplexed sensing for cell function analysis.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Grooved step emulsification systems optimize the throughput of passive generation of monodisperse emulsions
    by Adam S. Opalski on February 21, 2019 at 12:00 am

    Lab Chip, 2019, 19,1183-1192DOI: 10.1039/C8LC01096J, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Adam S. Opalski, Karol Makuch, Yu-Kai Lai, Ladislav Derzsi, Piotr GarsteckiA novel step emulsifier allows high throughput production of monodisperse emulsions. Additionally, different modes of droplet production are investigated.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • 3D impedimetric sensors as a tool for monitoring bacterial response to antibiotics
    by S. Brosel-Oliu on February 20, 2019 at 12:00 am

    Lab Chip, 2019, 19,1436-1447DOI: 10.1039/C8LC01220B, PaperS. Brosel-Oliu, O. Mergel, N. Uria, N. Abramova, P. van Rijn, A. BratovA novel strategy for selective immobilization of bacteria on a 3D impedimetric transducer for sensing antimicrobial reagents.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Inertial focusing with sub-micron resolution for separation of bacteria
    by Javier Cruz on February 19, 2019 at 12:00 am

    Lab Chip, 2019, 19,1257-1266DOI: 10.1039/C9LC00080A, Paper Open Access &nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Javier Cruz, Tiscar Graells, Mats Walldén, Klas HjortInertial focusing in curved channels is demonstrated for particles between 0.5 and 2.0 μm in diameter; a range of biological relevance since it comprises a multitude of bacteria and organelles of eukaryotic cells.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Separating extracellular vesicles and lipoproteins via acoustofluidics
    by Mengxi Wu on February 18, 2019 at 12:00 am

    Lab Chip, 2019, 19,1174-1182DOI: 10.1039/C8LC01134F, PaperMengxi Wu, Chuyi Chen, Zeyu Wang, Hunter Bachman, Yingshi Ouyang, Po-Hsun Huang, Yoel Sadovsky, Tony Jun HuangExtracellular vesicles and lipoprotein contents are separated based on their acoustic constrast factors.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Lab-on-a-Film disposable for genotyping multidrug-resistant Mycobacterium tuberculosis from sputum extracts
    by Alexander C. Kukhtin on February 15, 2019 at 12:00 am

    Lab Chip, 2019, 19,1217-1225DOI: 10.1039/C8LC01404C, PaperAlexander C. Kukhtin, Thomas Sebastian, Julia Golova, Alex Perov, Christopher Knickerbocker, Yvonne Linger, Arial Bueno, Peter Qu, Michael Villanueva, Rebecca C. Holmberg, Darrell P. Chandler, Christopher G. CooneyMultiplex PCR and hybridization occur within a closed-amplicon laminate, which includes gel arrays printed on unmodified and untreated plastic film.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • Soil granular dynamics on-a-chip: fluidization inception under scrutiny
    by Morgane Houssais on February 15, 2019 at 12:00 am

    Lab Chip, 2019, 19,1226-1235DOI: 10.1039/C8LC01376D, PaperMorgane Houssais, Charles Maldarelli, Jeffrey F. MorrisTo model soil dynamics, the particle scale deformation of sediment bed is measured as a controlled porous flow passes through it.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • A novel technique for in situ uniaxial tests of self-assembled soft biomaterials
    by Mohamed Elhebeary on February 6, 2019 at 12:00 am

    Lab Chip, 2019, 19,1153-1161DOI: 10.1039/C8LC01273C, PaperMohamed Elhebeary, Md Abul Bashar Emon, Onur Aydin, M. Taher A. SaifA novel method for the characterization of soft biomaterials and 3D tissues with living cells. Samples are self-assembled from a liquid droplet of the biomaterial on the testing stage.The content of this RSS Feed (c) The Royal Society of Chemistry […]

  • High-throughput mechanotransduction in Drosophila embryos with mesofluidics
    by Ardon Z. Shorr on February 4, 2019 at 12:00 am

    Lab Chip, 2019, 19,1141-1152DOI: 10.1039/C8LC01055B, PaperArdon Z. Shorr, Utku M. Sönmez, Jonathan S. Minden, Philip R. LeDucA mesofluidic device allows alignment, immobilization, compression, imaging, and recovery of hundreds of live Drosophila embryos to investigate mechanotransduction.The content of this RSS Feed (c) The Royal Society of Chemistry […]

Analytical Chemistry: Latest Articles (ACS Publications) latest articles published in Analytical Chemistry

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    • A self-powered microfluidic chip integrated with fluorescent microscopic counting for biomarkers assay
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Jian Yang, Xinli Liu, Yongchun Pan, Jingjing Yang, Bangshun He, Yunzhi Fu, Yujun SongAbstractSandwich immunoassay plays a significant role in disease diagnostics and prognosis. However, this technology always requires cumbersome manual washing procedures and well trained operators. To address the issues, we made an effort to develop a self-powered microfluidic chip (SP-Chip) to accomplish multiple washing processes and antigen-antibody binding reaction automatically in one-step sliding manner. This […]

    • Highly sensitive sensors based on quasi-2D rGO/SnS<sub>2</sub> hybrid for rapid detection of NO<sub>2</sub> gas
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Ming Cheng, Zepei Wu, Guannan Liu, Lianjing Zhao, Yuan Gao, Bo Zhang, Fangmeng Liu, Xu Yan, Xishaung Liang, Peng Sun, Geyu LuAbstractNitrogen dioxide (NO2) sensing is important in terms of the agriculture development and healthcare monitoring. However, relatively poor recovery kinetics at a low temperature is still a problem for NO2 sensing and remains to be solved. In this work, we combine the excellent sensing properties and gas adsorption capacity of two- dimensional (2D) tin disulfide (SnS2) […]

    • Ammonia sensing performance of a platinum nanoparticle-decorated tungsten trioxide gas sensor
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): I-Ping Liu, Ching-Hong Chang, Tzu Chieh Chou, Kun-Wei LinAbstractPlatinum nanoparticles (Pt NPs) are decorated on a sputtered tungsten tri-oxide (WO3) thin film to fabricate a high-performance ammonia gas sensor. These Pt NPs are synthesized by drop coating combined with UV irradiation approaches. Compared to a sensor comprising pristine WO3 thin film, the studied Pt NP/WO3 device shows a significant improvement in ammonia sensing response. The experimental results indicate that a high sensing […]

    • Detection of hexanal in humid circumstances using hydrophobic molecularly imprinted polymers composite
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Wei Chen, Zhenhe Wang, Shuang Gu, Jun WangAbstractHexanal is a specific volatile organic compound (VOC) for monitoring the quality of various agricultural products and a biomarker for diagnosing lung cancer of human beings. However there is no existing hexanal gas sensor with high sensitivity and selectivity for hexanal detection in the presence of water vapor. Addressing this challenge, a quartz crystal microbalance (QCM) gas sensor modified with a hydrophobic molecularly imprinted polymers (MIPs) […]

    • Fabrication of Co<sub>3</sub>O<sub>4</sub> nanowires assembled on the surface of hollow carbon spheres for acetone gas sensing
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Chunmei Zhang, Lei Li, Lin Hou, Wei ChenAbstractSensitive analysis of specific volatile organic compounds from exhaled breath from human body can provide useful information for early diagnosis of diseases, and therefore, design and fabrication of sensitive gas sensing materials with low working temperature have attracted extensive attention. In this study, Co3O4 nanowires assembled on the surface of hollow carbon spheres (Co3O4 NWs-HCSs) is successfully realized. Cobalt carbonate hydroxide nanowires […]

    • Surface plasmons coupled two-dimensional photonic crystal biosensors for Epstein-Barr virus protein detection
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Yung-Tsan Chen, Yu-Yang Liao, Chien-Chun Chen, Hui-Hsin Hsiao, Jian-Jang HuangAbstractThe fundamental detection scheme of typical grating or photonic crystal (PhC) sensors relies on the correlation of the diffraction behaviors with the refractive index of target analyte. For biomaterial detection, a thin gold film is usually deposited on the sensor surface so that cross linkers can be anchored before functionalizing the device. The nanoscale metallic film suggests plasmonic resonances play a critical […]

    • Polymer-infiltrated SiO<sub>2</sub> inverse opal photonic crystals for colorimetrically selective detection of xylene vapors
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Yuqi Zhang, Yimin Sun, Jiaqi Liu, Pu Guo, Zhongyu Cai, Ji-Jiang WangAbstractXylenes are common aromatic volatile organic compounds, which can cause severe environmental pollution and healthy issues. The current instrumental detection methods are generally expensive, time-consuming, complex, and unable to be used for on-site detection. It is thus highly desirable to develop an efficient method for the detection of xylenes. In this study, we report the development of a polymer infiltrated SiO2 inverse […]

    • 4-mercaptobenzoic acid modified silver nanoparticles-enhanced electrochemical sensor for highly sensitive detection of Cu<sup>2+</sup>
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Mi Zhou, Long Han, Dongmei Deng, Zhen Zhang, Haibo He, Lin Zhang, Liqiang LuoAbstractIn this work, a novel metal-enhanced electrochemical sensor based on silver nanoparticles (AgNPs) signal amplification was presented for highly sensitive determination of Cu2+. Gold nanoparticles were electrochemically deposited on fluorine doped tin oxide, and then 4-mercaptobenzoic acid (MBA) was self-assembled onto the surface of gold nanoislands through S-Au bond. The carboxyl of MBA could be chelated with target […]

    • A novel electrochemical sensor for the detection of oxidative stress and cancer biomarker (4-nitroquinoline <em>N</em>-oxide) based on iron nitride nanoparticles with multilayer reduced graphene nanosheets modified electrode
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Umamaheswari Rajaji, Akilarasan Muthumariyappan, Shen-Ming Chen, Tse-Wei Chen, R. Jothi RamalingamAbstractHerein, a novel iron nitride nanoparticles (Fe2N NPs) decorated reduced graphene oxide (rGOS) nanocomposite have been designed through a solvothermal method and followed by a nitridation process. After then, as-synthesized Fe2N NPs@rGOS was characterized by HRTEM, FESEM, XPS, XRD, and EIS. Furthermore, the nanocomposite modified SPCE (screen-printed carbon electrode) shows excellent […]

    • Electrochemical immunosensors with protease as the signal label for the generation of peptide-Cu(II) complexes as the electrocatalysts toward water oxidation
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Ning Xia, Dehua Deng, Suling Yang, Yuanqiang Hao, Luyan Wang, Yuwei Liu, Cuixia An, Qiuyang Han, Lin LiuAbstractThis work reported that protease can be used as the signal label to amplify the signal of electrochemical immunosensors. Carbon nanotube (CNT) was used as the carrier of recognition antibody and signal label. The nanolabel was captured by sensor electrode via a sandwich-type immunoreaction. Protease on the surface of nanolabel can catalyze the hydrolysis of peptide substrate to liberate an […]

    • High resolution potassium sensing with large-area graphene field-effect transistors
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Ibrahim Fakih, Alba Centeno, Amaia Zurutuza, Boutheina Ghaddab, Mohamed Siaj, Thomas SzkopekAbstractWe demonstrate large-area graphene based ion sensitive field effect transistors (ISFETs) with potassium ionophore sensing layers. Graphene ISFETs encapsulated with an ultra-thin hydrophobic layer, parylene C, and active areas ∼0.4 cm2 are characterized by an rms current noise as low as 5 nA in a 60 Hz electrical bandwidth, field effect mobilities up to […]

    • Direct growth of 3D porous (Ni-Co)<sub>3</sub>S<sub>4</sub> nanosheets arrays on rGO-PEDOT hybrid film for high performance non-enzymatic glucose sensing
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Alan Meng, Xiangcheng Yuan, Zhenjiang Li, Kun Zhao, Liying Sheng, Qingdang LiAbstractA binder-free, rapid and low-cost electrodeposition technology for growing 3D porous (Ni-Co)3S4 nanosheets arrays on glassy carbon electrode (GCE) functionalized by reduced graphene oxide-poly (3,4-ethylenedioxythiophene) (rGO-PEDOT) hybrid film is successfully developed to construct a sensor for non-enzymatic glucose sensing. The main experimental variables affected on the electrochemical performance are optimized. […]

    • A mitochondrial-targeted fluorescent probe to sense pH and HOCl in living cells
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Fengyun Qin, Yongru Zhang, Jianming Zhu, Yan Li, Wenbo Cao, Yong YeAbstractA series of rosamine dyes were designed and synthesized through one-step reaction. Among them, bifunctional fluorescent probe RosPO(OH)2 showed excellent water solubility and large molar extinction coefficient. RosPO(OH)2 underwent a two-step ionization process as the pH value of the HEPES buffer increased, accompanied a blue shift of UV absorption and an enhancement of fluorescence intensity. This means it can be used as a pH […]

    • Direct immunomagnetic detection of low abundance cardiac biomarker by aptamer DNA nanocomplex
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Ka-Wang Wong, Di Xu, Dinggeng He, Man Shing Wong, Hung-Wing LiAbstractAn early and rapid diagnosis of acute myocardial infraction (MI) by serum biomarker quantification is vital for boosting up treatment efficacy and survival rate; however, it still remains challenging due to ultralow biomarkers content and the emergent nature of the disease. In view of these challenges, a single-step target capturing method for cardiac Troponin I (cTnI), the major cardiac biomarker of MI, was developed. The […]

    • Fabrication of 1D Zn<sub>2</sub>SnO<sub>4</sub> nanowire and 2D ZnO nanosheet hybrid hierarchical structures for use in triethylamine gas sensors
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Fengjun Liu, Xiaoyan Chen, Xinzhen Wang, Ye Han, Xiaojie Song, Jian Tian, Xuanmeng He, Hongzhi CuiAbstractIn this work, unique Zn2SnO4–ZnO hierarchical structures composed of one-dimensional Zn2SnO4 nanowires and two-dimensional ZnO nanosheets were successfully synthesized via a facile hydrothermal method combined with calcination. The Zn2SnO4 nanowires bridged across the ZnO nanosheets, which played an important role in electron transmission. Compared with pure Zn2SnO4 nanowires and pure ZnO […]

    • Chicken immunoglobulin Y based FRET assay for TSST-1 detection and its validation onto clinical isolates
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): J. Achuth, R.M. Renuka, S. Naveen, K. KadirveluAbstractStaphylococcus aureus (S. aureus) is commensal bacteria implicated in various opportunistic infections worldwide. Their numerous virulence factors along with mounting antibiotic resistance is an ominous problem associated with its clinical management. Among the numerous S. aureus virulence factors, toxic shock syndrome toxin 1 (TSST-1) is a superantigen that is pivotal in life-threatening multisystem disorder. The present study reports the […]

    • Rapid isolation of <em>Escherichia coli</em> from water samples using magnetic microdiscs
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Keisha Y. Castillo-Torres, David P. Arnold, Eric S. McLamoreAbstractThis work introduces a method for rapid isolation of target bacterial cells using “bacteria-sized,” gold-coated magnetic microdiscs (1.5 μm in diameter, 80 nm in thickness). These microdiscs are functionalized with DNA aptamers for selectively isolating Escherichia coli cells from lab-prepared and environmental water samples at concentrations as low as 102 CFU/100 mL with no enrichment. This […]

    • Building of a flexible microfluidic plasmo-nanomechanical biosensor for live cell analysis
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): V. Solis-Tinoco, S. Marquez, T. Quesada-Lopez, F. Villarroya, A. Homs-Corbera, L.M. LechugaAbstractBiosensor devices can constitute an advanced tool for monitoring and study complex dynamic biological processes, as for example cellular adhesion. Cellular adhesion is a multipart process with crucial implications in physiology (i.e. immune response, tissue nature, architecture maintenance, or behaviour and expansion of tumor cells). This work focuses on offering a controlled methodology in order to […]

    • The real-time monitoring of drug reaction in HeLa cancer cell using temperature/impedance integrated biosensors
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Taekyun Yoo, Kyungsuk Lim, Md. Tipu Sultan, Ji Seung Lee, Junhee Park, Hyung Woo Ju, Chanhum Park, Moongyu JangAbstractIn this work, the temperature/impedance integrated sensor is manufactured using a semiconductor process for the simultaneous monitoring of the temperature and impedance variations. Temperature Coefficient of Resistance (TCR) value of the manufactured Platinum temperature sensor on the slide glass is evaluated as 2003.65 ppm/℃, giving the temperature inaccuracy less than […]

    • Facile construction of imidazole functionalized polysiloxanes by thiol-ene “Click” reaction for the consecutive detection of Fe<sup>3+</sup> and amino acids
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Yujing Zuo, Yu Zhang, Zhiming Gou, Weiying LinAbstractNovel imidazole-functionalized polysiloxane (PMMS-IM) was synthesized by facile thiol-ene “click” chemistry. PMMS-IM exhibited strong photoluminescence excited by a wavelength of 365 nm. In addition, the consecutive response to Fe3+ and amino acids by fluorescence quenching and lighting has been investigated. The sequence response of PMMS-IM towards Fe3+ and amino acids exhibit fine selectivity. Moreover, PMMS-IM represented a […]

    • Development of high-luminescence perovskite quantum dots coated with molecularly imprinted polymers for pesticide detection by slowly hydrolysing the organosilicon monomers in situ
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Lei Tan, Manli Guo, Jiean Tan, Yuanyuan Geng, Shuyi Huang, Youwen Tang, Chaochin Su, ChunChe Lin, Yong LiangAbstractIn spite of the high-brightness of perovskite quantum dots (QDs), their instability and sensitive to oxygen and moisture are still major challenges that obstruct their analytical applications. This work demonstrates the fabrication and application of perovskite CsPbBr3 QDs embedded in a molecularly imprinted polymer (MIP) for specific and sensitive detection of phoxim in real samples. […]

    • Highly fluorescent polyethyleneimine protected Au<sub>8</sub> nanoclusters: One-pot synthesis and application in hemoglobin detection
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Fengniu Lu, Hongwei Yang, Zhiqin Yuan, Takashi Nakanishi, Chao Lu, Yan HeAbstractGold nanoclusters (Au NCs) with atomic precision have huge application potentials in chemo/bio sensing, catalysis, and energy conversion. However, a precise atomic control of Au NCs still remains a great challenge. Herein, we developed a facile one-pot and top-down strategy to synthesize eight-atom numbered Au NCs (Au8 NCs), aiming to understand their fundamental physicochemical properties and explore their potential […]

    • Solution-gated graphene field effect transistor for TP53 DNA sensor with coplanar electrode array
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Hyo Eun Kim, Ariadna Schuck, June Ho Lee, Yong-Sang KimAbstractThis study presents a solution-gated graphene field effect transistor (GFET) for a TP53 DNA sensor using a unique coplanar electrode array integrated with a microfluidic chip. The integrated microfluidic channel controls the exact amount of solution to be delivered. The cancer-related gene, TP53, was applied over the graphene active layers to monitor the sensing performance of the solution-gated GFET. After immobilization of the probe […]

    • An integrated one-step assay combining thermal lysis and loop-mediated isothermal DNA amplification (LAMP) in 30 min from <em>E. coli</em> and <em>M. smegmatis</em> cells on a paper substrate
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Priyanka Naik, Siddhant Jaitpal, Prasad Shetty, Debjani PaulAbstractDeveloping sensors for food safety, soil analysis, water quality monitoring and healthcare often requires distinguishing between different species of bacteria. The most rapid, sensitive and specific method to identify bacteria is to analyse their DNA sequence, which comprises of disinfection and lysis of bacterial cells, amplification of the isolated DNA and detection of the amplified sequence. Seamless integration of these steps on […]

    • Ultrasensitive graphene quantum dots-based catalytic hairpin assembly amplification resonance light scattering assay for p53 mutant DNA detection
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Shuang Wang, Feng Zhang, Chunyan Chen, Changqun CaiAbstractIn this work, a simple, enzyme-free and ultrasensitive resonance light scattering (RLS) method was developed based on graphene quantum dots (GQDs) with a catalytic hairpin assembly amplification strategy for selective detection of mutant DNA. This method contains two probes, GQDs-H1 and GQDs-H2. Two partially complementary hairpins (H1 and H2) are ingeniously and rationally designed, and they can't spontaneously hybridize with each other in […]

    • A non-enzymatic photoelectrochemical glucose sensor based on BiVO<sub>4</sub> electrode under visible light
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Shan Wang, Shaoping Li, Wenwen Wang, Mengting Zhao, Jiaofeng Liu, Haifeng Feng, Yiming Chen, Qi Gu, Yi Du, Weichang HaoAbstractA non-enzymatic photoelectrochemical (PEC) glucose sensor based on nanoporous bismuth vanadate (BiVO4) electrode is fabricated on fluorine doped tin oxide by electrochemical deposition. The photogenerated holes of BiVO4 show a strong oxidizing ability, with adsorption of glucose on the surface of BiVO4, agreeing well with the classical Langmuir adsorption model. Under visible […]

    • Tetraphenylethene decorated hyperbranched poly(amido amine)s as metal/organic-solvent-free turn-on AIE probe for specific pyrophosphate detection
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Cheng Li, Yu Chen, Lijun Yang, Congrou Zhang, Bin Wang, Yong WangAbstract“Turn-on” fluorescent materials in the absence of metal and organic solvent are highly desirable as bioprobes to selectively and sensitively detect pyrophosphate (PPi) anion. In this work, we embedded tetraphenylethene (TPE) inside the relatively rigid hyperbranched poly(amido amine) (HPA) to afford highly water soluble TPE-HPA materials, where the TPE fluorescence was pre-quenched in water by the hyperbranched […]

    • Focused surface acoustic waves induced microdroplets generation and its application for microgels
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): Shaobo Jin, Xueyong Wei, Zhen Liu, Juan Ren, Zhuangde Jiang, Chris Abell, Ziyi YuAbstractWe demonstrate a novel microdroplets generation method by using focused surface acoustic waves (FSAW). The method differs from previous work in the mechanism and the geometry structure of the chip, which is depend on FSAW rather than flow shearing. The acoustic radiation force arising from FSAW acts on the oil-water interface, breaking up the water into microdroplets whose size can be controlled by tuning the […]

    • Highly selective and sensitive CH<sub>4</sub> gas sensors based on flame-spray-made Cr-doped SnO<sub>2</sub> particulate films
      on January 1, 1970 at 12:00 am

      Publication date: 15 July 2019Source: Sensors and Actuators B: Chemical, Volume 291Author(s): K. Bunpang, A. Wisitsoraat, A. Tuantranont, S. Singkammo, S. Phanichphant, C. LiewhiranAbstractIn this research, flame-spray-made 0–2 wt% Cr-doped SnO2 nanoparticles were synthesized and methodically studied for specific detection of methane (CH4) for the first time. From characterizations using X-ray diffraction, X-ray photoelectron spectroscopy, scanning/transmission electron microscopy and nitrogen adsorption, Cr was found to form substitutional solid solution in 5–20 nm […]

    • Selective detection of organic vapors using TiO<sub>2</sub> nanotubes based single sensor at room temperature
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Prateek Bindra, Arnab HazraAbstractThe present study demonstrates a new measurement technique for the selective detection of multiple volatile organic compounds (VOCs) at room temperature (300 K) by using a single sensor. Electrochemically grown TiO2 nanotubes based sandwich-structured device was fabricated to realize the selectivity technique. The proposed method of selective detection of VOCs involved simultaneous measurement of both resistive and capacitive responses of the sensor upon […]

    • UV-activated gold decorated rGO/ZnO heterostructured nanocomposite sensor for efficient room temperature H<sub>2</sub> detection
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Q.A. Drmosh, A.H. Hendi, M.K. Hossain, Z.H. Yamani, R.A. Moqbel, Abdo Hezam, M.A. GondalAbstractExtended surface area in addition to higher conductivity and abundant free electrons/holes generation has been key players for any efficient sensor design. Therefore, contribution from graphene as highest conductive material and plasmonics from gold (Au) were expected to facilitate efficient zinc oxides (ZnO) nanostructures-based Hydrogen gas detection. We have presented herewith a facile route to […]

    • Single-crystalline porous nanoplates-assembled ZnO hierarchical microstructure with superior TEA sensing properties
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Yanwei Li, Zhenhua Tao, Na Luo, Guang Sun, Bo Zhang, Honghong Jin, Hari Bala, Jianliang Cao, Zhanying Zhang, Yan WangAbstractFabricating hierarchical structures has emerged as a powerful strategy to improve the gas-sensing performance of metal oxide semiconductor (MOS). In this work, we reported the synthesis of a hierarchical microstructure (HMS) of ZnO via a reliable sacrificial template method and its superior sensing performance to triethylamine (TEA). The synthesized ZnO HMS features an orderly […]

    • Hydrodynamic evaluation of gas testing chamber: Simulation, experiment
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Fatima-Ezahra Annanouch, Gilles Bouchet, Pierre Perrier, Nicolas Morati, Christelle Reynard-Carette, Khalifa Aguir, Virginie Martini-Laithier, Marc BendahanAbstractGas concentration measurements by means of metal oxide microsensors represent a promising issue due to several advantages (size, low cost, power consumption, reliability…). However, improvements are required to increase performances of complete experimental systems including microsensor and testing chamber at least. This paper deals […]

    • Temperature dependent response/recovery characteristics of Pd/Ni thin film based hydrogen sensor
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Qi Liu, Jinyuan Yao, Yipin Wang, Yunna Sun, Guifu DingAbstractThis paper demonstrates a new phenomenon that the response performance of Pd/Ni film in the heating mode improves a lot compared with room temperature. Based on the phenomenon, Pd/Ni thin film resistive hydrogen sensor integrated with heating resistance wire is fabricated to operate in the heating mode. Through the tests at different operating temperatures, we find that there exists an optimum temperature of 75 °C, when the […]

    • Oxygen vacancy modulation of commercial SnO<sub>2</sub> by an organometallic chemistry-assisted strategy for boosting acetone sensing performances
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Sen Liu, Shang Gao, Ziying Wang, Teng Fei, Tong ZhangAbstractOxygen vacancies play a critical role in the sensing performances for metal oxides-based chemiresistor-type sensors. Developing facile and effective strategies for fabricating metal oxides with controllable oxygen vacancies is in great demand but remains paramount challenge. Herein, a novel organometallic chemistry-assisted method is reported to prepare SnO2 samples containing controllable surface oxygen vacancies. This new approach combines […]

    • Highly sensitive and selective ethanol detection at room temperature utilizing holey SWCNT-Sn/SnO<sub>2</sub> nanocomposites synthesized by microwave irradiation
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Youngmin Byoun, Suyoung Park, Changhyun Jin, Young-Jun Song, Sun-Woo ChoiAbstractCarbon-based nanocomposites that can operate at room temperature (25 °C) are potential sensing materials for application in chemical sensors owing to their unique physical properties such as extremely large surface-to-volume ratios and very high carrier mobility. However, most studies on sensing materials consisting of carbon-based nanocomposites have focused on synthesizing various material systems that […]

    • Template-free synthesis of cubic-rhombohedral-In<sub>2</sub>O<sub>3</sub> flower for ppb level acetone detection
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Fang Chen, Man Yang, Xi Wang, Yang Song, Lanlan Guo, Ning Xie, Xueying Kou, Xiumei Xu, Yanfeng Sun, Geyu LuAbstractAnalyzing volatile organic compounds in exhaled breath is a noninvasive method that has potential for disease assessment. Herein, acetone sensors based on porous In2O3 flowers are synthesized through a facile solvothermal method. Structural characterizations demonstrate that the three-dimensional In2O3 flower-like structure comprises porous ultrathin two-dimensional nanosheets. The […]

    • UV light irradiation enhanced gas sensor selectivity of NO<sub>2</sub> and SO<sub>2</sub> using rGO functionalized with hollow SnO<sub>2</sub> nanofibers
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Weiwei Li, Jiahui Guo, Li Cai, Wenzhi Qi, Yilin Sun, Jian-Long Xu, Mengxing Sun, Hongwei Zhu, Lan Xiang, Dan Xie, Tianling RenAbstractHerein, to enhance selective detection of NO2 and SO2 using a single device, an ultraviolet (UV) light activated gas sensor has been reported based on reduced graphene oxide (rGO) functionalized with hollow SnO2 nanofibers (NFs) at room temperature. The porous hollow SnO2 NFs are synthesized using electrospinning and calcination treatment, then different contents of […]

    • Ppb-level nitric oxide photoacoustic sensor based on a mid-IR quantum cascade laser operating at 52 °C
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Hongpeng Wu, Xukun Yin, Lei Dong, Zhiwei Jia, Jinchuan Zhang, Fengqi Liu, Weiguang Ma, Lei Zhang, Wangbao Yin, Liantuan Xiao, Suotang Jia, Frank K. TittelAbstractA ppb-level nitric oxide (NO) photoacoustic sensor was reported for outdoor environmental monitoring. The sensor employed a continuous wave (CW), distributed feedback (DFB), mid-infrared (mid-IR) quantum cascade laser (QCL) operating at a high temperature of 52 °C, which allow avoiding any water-cooling systems and thereby reduces its […]

    • Understanding on the ethanol sensing mechanism of atmospheric plasma sprayed 25 wt. % WO<sub>3</sub>-75 wt. % SnO<sub>2</sub> coating
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): V. Ambardekar, P.P. Bandyopadhyay, S.B. MajumderAbstractAtmospheric plasma spray was utilized to fabricate 25 wt. % WO3-75 wt. % SnO2 composite coating on alumina substrate for ethanol sensing. Analyzing the conductance transients we have demonstrated that the response transients follow Freundlich adsorption isotherm. From isotherm analyses we have estimated the activation energy of the adsorption of test vapors (Ea) and heat of adsorption (Q) as a function of concentration and reported […]

    • Highly sensitive ethylene sensors using Pd nanoparticles and rGO modified flower-like hierarchical porous α-Fe<sub>2</sub>O<sub>3</sub>
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Bo Li, Minqiang Li, Fanli Meng, Jinhuai LiuAbstractTo develop a feasible approach to detect ethylene in low concentration is of great significance to reduce losses of farm products during storage and logistics. However, it is really difficult to detect it due to the lack of polar chemical functionality of ethylene and its small size. While appropriate Pd nanoparticles (NPs) and reduced graphene oxide (rGO) modified flower-like hierarchical porous α-Fe2O3 was designed and successfully synthesized […]

    • An electrochemical model of an amperometric NO<sub>x</sub> sensor
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Masoud Aliramezani, Charles Robert Koch, Marc Secanell, Robert E. Hayes, Ron PatrickAbstractTo help design future amperometric NOx sensors, a physics-based sensor model that includes diffusion and electrochemical submodels is developed. It is shown that NO is partly reduced in the O2 sensing chamber which affects NO concentration in the O2 sensing and in the NOx sensing chamber. Therefore, the electrochemical model is developed to simulate partial reduction of NOx on the O2 sensing electrode and […]

    • All-carbon fiber-based chemical sensor: Improved reversible NO<sub>2</sub> reaction kinetics
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Seon-Jin Choi, Dong-Myeong Lee, Hayoung Yu, Ji-Soo Jang, Min-Hyeok Kim, Joon-Young Kang, Hyeon Su Jeong, Il-Doo KimAbstractAll-carbon fiber-based chemiresistor is fabricated by assembling reduced graphene oxide (RGO) fiber and carbon nanotube (CNT) fiber as reversible NO2 sensing layer and flexible heater, respectively. Both graphene oxide (GO) and CNT fibers were synthesized by wet-spinning technique facilitating lyotropic nematic liquid crystal (LC) property. Randomly entangled CNT fiber-based […]

    • Dimethyl sulfoxide-assisted hydrothermal synthesis of Co<sub>3</sub>O<sub>4</sub>-based nanorods for selective and sensitive diethyl ether sensing
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Rui Jiang, Lihua Jia, Xiangfeng Guo, Zhenlong Zhao, Jinping Du, Xin Wang, Ping Wang, Fenglan XingAbstractHerein, the mesoporous Co3O4-based nanorods were obtained by heat treatment of dimethyl sulfoxide-assisted hydrothermal-synthesized products at 300 °C and probe the composition, structure and morphology by several instrumental techniques. Additionally, we investigate the ability of the nanorods to sense several gaseous organic compounds, such as diethyl ether, ethanol, and acetone, […]

    • Highly sensitive and selective isoprene sensing performance of ZnO quantum dots for a breath analyzer
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Yunji Park, Ran Yoo, Seung ryull Park, Jun Ho Lee, Hwaebong Jung, Hyun-Sook Lee, Wooyoung LeeAbstractWe report the quantum-size effect on the sensing properties of ZnO nanoparticles for the detection of isoprene. For this purpose, two types of ZnO particles with different sizes, including nanoparticles (NPs, ˜25 nm) and quantum dots (QDs, ˜5 nm), were prepared by a wet chemical method. The ZnO QDs exhibited excellent sensing performance to 1 ppm isoprene compared to […]

    • Fabrication of heterostructured <em>p</em>-CuO/<em>n</em>-SnO<sub>2</sub> core-shell nanowires for enhanced sensitive and selective formaldehyde detection
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Li-Yuan Zhu, Kaiping Yuan, Jian-Guo Yang, Hong-Ping Ma, Tao Wang, Xin-Ming Ji, Ji-Jun Feng, Anjana Devi, Hong-Liang LuAbstractHighly sensitive and selective gas sensors based on heterostructured p-CuO/n-SnO2 core-shell nanowires (NWs) with precisely controlled shell thickness were synthesized through a sequential process combining a solution processing and atomic layer deposition. The gas sensing devices were fabricated on micro-electromechanical systems, which has triggered great research interest […]

    • Electrochemical sensor to environmental pollutant of acetone based on Pd-loaded on mesoporous In<sub>2</sub>O<sub>3</sub> architecture
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Xiaojing Liu, Kunrong Zhao, Xiaoli Sun, Xinping Duan, Chong Zhang, Xijin XuAbstractIn this work, a series of Pd sensitized mesoporous In2O3 nanocomposites with 1.0, 1.5 and 2.0 mol% Pd-loading amount were obtained by a green and facile precipitation method, and evaluated their gas sensing properties as compared to pristine In2O3. According to the results of comparative sensing performance tests, the gas sensor based on 1.5 mol% Pd-loaded In2O3 displays prominent sensitivity and […]

    • Shape control and selective decoration of Zn<sub>2</sub>SnO<sub>4</sub> nanostructures on 1D nanowires: Boosting chemical–sensing performances
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Tingting Zhou, Xiupeng Liu, Rui Zhang, Yubing Wang, Tong ZhangAbstractOne–dimensional (1D) heterostructures are promising for the fascinating physical/chemical properties. However, the selective deposition of innovative materials as efficient active sites on the backbone material is still challenging and meaningful. Herein, a universal strategy is presented to synthesize the novel 1D heterostructure, which is constituted of Mn3O4 nanowires (Mn3O4 NWs) and nano–sized Zn2SnO4 subunits with […]

    • Synergy between Au and In<sub>2</sub>O<sub>3</sub> microspheres: A superior hybrid structure for the selective and sensitive detection of triethylamine
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Lingli Zheng, Tiantian Ma, Yingqiang Zhao, Yongshan Xu, Li Sun, Jun Zhang, Xianghong LiuAbstractDesign of metal/semiconductor hybrid nanostructures provides an important strategy for developing efficient chemical gas sensors. Herein, a highly sensitive gas sensing material for detection of triethylamine is designed by loading Au nanoparticles on porous In2O3 microspheres. The In2O3 microspheres are prepared by thermally annealing the precursor of 3D nanosheets assembled In2S3 microspheres. Then, Au […]

    • An acetone gas sensor based on nanosized Pt-loaded Fe<sub>2</sub>O<sub>3</sub> nanocubes
      on January 1, 1970 at 12:00 am

      Publication date: 1 July 2019Source: Sensors and Actuators B: Chemical, Volume 290Author(s): Shendan Zhang, Mingjie Yang, Kunyu Liang, Ayse Turak, Bingxue Zhang, Da Meng, Chuanxi Wang, Fengdong Qu, Wenlong Cheng, Minghui YangAbstractNanosized Pt-loaded Fe2O3 nanocubes are prepared through, successively, a simple hydrothermal reaction, two-step annealing process and finally reduction with NaBH4 of H2PtCl4. The resultant Pt decorated Fe2O3 nanocubes, made up of Fe2O3 nanoplatelets, are hierarchical, hollow and porous, with an average edge length of 200–300 nm. The sensor based on […]

    Microsystems & Nanoengineering - nature.com technology Microsystems & Nanoengineering is an international open access journal, publishing original articles and reviews covering all aspects of microsystems and nanoengineering from fundamental to applied research.

    • Ion beam etching redeposition for 3D multimaterial nanostructure manufacturing
      by B. X. E. Desbiolles on April 22, 2019 at 12:00 am

      Ion beam etching redeposition for 3D multimaterial nanostructure manufacturingIon beam etching redeposition for 3D multimaterial nanostructure manufacturing, Published online: 22 April 2019; doi:10.1038/s41378-019-0052-7Ion beam etching redeposition for 3D multimaterial nanostructure manufacturing […]

    • Correction to: A microfluidic platform for continuous monitoring of dopamine homeostasis in dopaminergic cells
      by Yue Yu on April 22, 2019 at 12:00 am

      Correction to: A microfluidic platform for continuous monitoring of dopamine homeostasis in dopaminergic cellsCorrection to: A microfluidic platform for continuous monitoring of dopamine homeostasis in dopaminergic cells, Published online: 22 April 2019; doi:10.1038/s41378-019-0058-1Correction to: A microfluidic platform for continuous monitoring of dopamine homeostasis in dopaminergic cells […]

    • Building a Casimir metrology platform with a commercial MEMS sensor
      by Alexander Stange on April 22, 2019 at 12:00 am

      Building a Casimir metrology platform with a commercial MEMS sensorBuilding a Casimir metrology platform with a commercial MEMS sensor, Published online: 22 April 2019; doi:10.1038/s41378-019-0054-5The Casimir effect is a quantum fluctuation force that exists between conducting surfaces separated by hundreds of nanometers, and the effect holds promise for application as a sensing tool in conjunction with an inexpensive micro-electromechanical system (MEMS) device. A team headed by Alexander Stange in the Bishop group at Boston University, United States, observed the Casimir effect under […]

    • Three dimensional printing of metamaterial embedded geometrical optics (MEGO)
      by Aydin Sadeqi on April 8, 2019 at 12:00 am

      Three dimensional printing of metamaterial embedded geometrical optics (MEGO)Three dimensional printing of metamaterial embedded geometrical optics (MEGO), Published online: 08 April 2019; doi:10.1038/s41378-019-0053-6A technique that uses large area 3D printing and metal layer patterning can realize complex optical devices at a fraction of the cost of typical fabrications. Sameer Sonkusale and colleagues from Tufts University in the United States designed geometric surface patterns, such as tiny forests of mushroom-topped cylinders, capable of interacting strongly with microwave light. […]

    • Scalable fabrication of sub-10 nm polymer nanopores for DNA analysis
      by Junseo Choi on April 8, 2019 at 12:00 am

      Scalable fabrication of sub-10 nm polymer nanopores for DNA analysisScalable fabrication of sub-10 nm polymer nanopores for DNA analysis, Published online: 08 April 2019; doi:10.1038/s41378-019-0050-9Researchers in the United States have developed a method to create nanopores smaller than 10 nanometers in a simple, controllable, cost-effective way. Sunggook Park’s team at Louisiana State University pressed an array of silicon microneedles into a polymer layer to produce pores of around 10 nm. The polymer is then briefly heated to make it reflow, causing the pores to […]

    • Machine learning metrology of cell confinement in melt electrowritten three-dimensional biomaterial substrates
      by Filippos Tourlomousis on March 25, 2019 at 12:00 am

      Machine learning metrology of cell confinement in melt electrowritten three-dimensional biomaterial substratesMachine learning metrology of cell confinement in melt electrowritten three-dimensional biomaterial substrates, Published online: 25 March 2019; doi:10.1038/s41378-019-0055-4Melt electrowriting (MEW) is an advanced manufacturing process for fabricating biomaterial substrates, and in conjunction with a machine-learning algorithm to classify cell shapes, enables a cell-based model with high cell shape homogeneity. Adjusting cell shape by altering the biophysical properties of the […]