Biomedical Microsystems

Posted on August 2, 2015 by Admin

Book Description

Author: Ellis Meng

Poised to dramatically impact human health, biomedical microsystems (bioMEMS) technologies incorporate various aspects from materials science, biology, chemistry, physics, medicine, and engineering. Reflecting the highly interdisciplinary nature of this area, Biomedical Microsystems covers the fundamentals of miniaturization, biomaterials, microfabrication, and nanotechnology, along with relevant applications.

Written by an active researcher who was recently named one of Technology Review’sYoung Innovators Under 35, the book begins with an introduction to the benefits of miniaturization. It then introduces materials, fabrication technology, and the necessary components of all bioMEMS. The author also covers fundamental principles and building blocks, including microfluidic concepts, lab-on-a-chip systems, and sensing and detection methods. The final chapters explore several important applications of bioMEMS, such as microdialysis, catheter-based sensors, MEMS implants, neural probes, and tissue engineering.

For readers with a limited background in MEMS and bioMEMS, this book provides a practical introduction to the technology used to make these devices, the principles that govern their operation, and examples of their application. It offers a starting point for understanding advanced topics and encourages readers to begin to formulate their own ideas about the design of novel bioMEMS. A solutions manual is available for instructors who want to convert this reference to classroom use.

Table of Contents

Introduction
Evolution of MEMS
Applications of MEMS
BioMEMS Applications
MEMS Resources
Text Goals and Organization
Miniaturization and Scaling

BioMEMS Materials
Traditional MEMS and Microelectronic Materials
Polymeric Materials for MEMS
Biomaterials

Microfabrication Methods and Processes for BioMEMS
Introduction
Microlithography
Doping
Micromachining
Wafer Bonding, Assembly, and Packaging
Surface Treatment
Conversion Factors for Energy and Intensity Units
Laboratory Exercises

Microfluidics
Introduction and Fluid Properties
Concepts in Microfluidics
Fluid-Transport Phenomena and Pumping
Flow Control
Laboratory Exercises

Lab-on-a-Chip or Micro Total Analysis Systems
Microanalytical Systems in Chemistry and Biology
Sample Pretreatment
Sample Introduction
Separations

Sensing and Detection Methods
Sensing and Detection
Sensor Characteristics
Principles of Physical Sensing
Biological and Chemical Detection Methods

Applications to Cells, Nucleic Acids, and Proteins
Cells
Nucleic Acids
Proteins

Clinical Monitoring
Flow Cytometry
Microdialysis
Catheter-Based Sensors
Endoscopy
Point of Care

MEMS Implants and Bioelectric Interfaces
Implantable MEMS
Microelectrodes and Neural Probes
Implantable Sensors
Drug Delivery
Tissue Engineering

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