Tumor Cells

CYTO 2016

June 11, 2016

INNOVATION: Image and Flow Technology Automated Microscopy Automated Sample Preparation Computation and Informatics Cell sorting and selection Facility management Flow cytometry instrumentation High content analysis High throughput [more...]

Open-source Laser Fabrication Lowers Costs For Cancer Research

January 31, 2016

Jordan Miller’s research team at Rice University has shown how to make copies of microwell sheets using polyurethane microneedle casts. (Photo courtesy of Jordan Miller/Rice University) In a move that slashes 90 percent of the cost [more...]

Blood-Brain Barrier Opened Noninvasively with Focused Ultrasound for the First Time

January 1, 2016

Opening the blood-brain barrier in a localized region to deliver chemotherapy to a tumor is a predicate for utilizing focused ultrasound for the delivery of other drugs, DNA-loaded nanoparticles, viral vectors, and antibodies to the brain [more...]

Detecting Cancer Cells Before They Form Metastases

November 25, 2015

Target cells (green) stick to the microarray platform (red). (Credit: Michael Hirtz / KIT) Many tumors spread: Single cancer cells migrate with blood flow through the body before they settle in new tissue. In this way, metastases may be [more...]

Capturing Cell Growth in 3D with Microfluidic Device

August 15, 2015

AIM Biotech’s microfluidics device (shown here) has an array of culturing sections, each with three chambers: a middle chamber for hydrogel and any cell type, and two side channels for culturing additional cell types. Replicating how [more...]

Scaffold-integrated Microchips Retrieve Cancer Cells

August 7, 2015

An integrated microfluidic chip design with an embedded 3-D hydrogel scaffold provides a transfer-rable microenvironment for the recovery and longitudinal study of captured circulating tumor cells. (Image Credit: TECHNOLOGY) A team of [more...]

Tiny Biochemical Sensor Provides Real-time Cancer Monitoring

August 5, 2015

Illustration of the tiny biochemical sensor that can be implanted in cancerous tissue during an initial biopsy (Image Credit: Michael Cima et al, MIT) In the battle against cancer, which kills nearly 8 million people worldwide each year, [more...]

Single-Cell Proteomics Is in the Chips

July 28, 2015

At Northeastern University, researchers are developing ScanDrop, a lab-on-a-chip biosensor approach that utilizes a well-mixed microfluidic device and a microsphere-based assay capable of performing near real-time diagnostics. ScanDrop has [more...]

3-D Organoids Grown from Patient Tumors Could Personalize Drug Screening

July 4, 2015

Cancer in 3-D (Image Credit: Wellcome Trust Sanger Institute) Three-dimensional cultures (or “organoids”) derived from the tumors of cancer patients closely replicate key properties of the original tumors, reveals a study [more...]

Microfluidic Chip Isolates Rare Tumor Cells

July 2, 2015

Love holds a microfluidic device, developed in Hidde Ploegh’s lab, that resembles a tiny ice cube tray, with individual compartments for each cell. Love and Ploegh designed the device, which can be used to isolate many individual [more...]

Microfluidics’ Watershed Moment

June 28, 2015

The HµRELflow™ cell-based assay system has three microfluidic devices on a biochip. Each device incorporates two cell culture compartments interconnected by microscale channels. Integrated micropumps recirculate culture media within the [more...]

Flow Cytometry On-a-Chip

June 10, 2015

IT’S MAGNETIC: Hakho Lee’s CTC counter features eight micro-Hall elements (yellow crosses, above), staggered to maximize detection accuracy. (Photo Credit: D. ISSADORE ET AL.) Originally an immunology tool and a fixture of cell [more...]

Nanoparticles: Great Promise Against Cancer

May 27, 2015

The advancement of nanotechnology in the past decade has driven the development of numerous medical applications. None of them is as promising as the use of targeted nanoparticles aimed to improve the treatment of cancer, which has serious [more...]

Microfluidic Chip Captures Clusters of Circulating Tumor Cells-NIH Study

May 21, 2015

Magnification of circulating tumor cell cluster captured by Cluster-Chip. (Image Credit: Sarioglu et al., Nature Methods) Researchers have developed a microfluidic chip that can capture rare clusters of circulating tumor cells, which [more...]

Automated Counting of Tumor Cells in Blood

May 17, 2015

The measuring channel that forms the key component of the cytometer is visible on the right-hand side of the image. (Photo Credit: Fraunhofer ICT-IMM) Biological and medical scientists have been using flow cytometry to count cancer [more...]