Organs-on-a-chip

Organ-on-a-chip: a New Model of Microfluidic Chip

April 22, 2018

Cells in a microwell and their growth after two days of perfusion An organ-on-a-chip is a microfluidic device with continuously perfused chambers in which cells are cultured to obtain functional units that mimic organ functions. The [more...]

Lab-grown Kidney Helps Test New Drugs

January 22, 2018

Figure 1 Draper designed PREDICT-96 so that researchers can easily integrate it into existing lab automation and screening tools. Drug use is extensive in the intensive care units of many hospitals, and although lifesaving, the practice is [more...]

CN Bio Innovations Use Organs-on-Chips to Improve Drug Development and Evaluation

October 29, 2017

Image credit: CN-Bio Innovation FDA and CN Bio will collaborate to characterize the performance of CN Bio’s Organs-on-Chips as a platform for potential use in drug development and regulatory evaluation, including safety testing prior [more...]

Wyss Institute’s Organ Chips Get Smart and Go Electric

June 14, 2017

This photograph of the Transepithelial Electrical Resistance- Multi-Electrode Array (TEER-MEA) chip shows the TEER electrodes in gold, the MEA collectors made of platinum in gray, and the two transparent parallel running microfluidic [more...]

Organs-on-chips: Small Market and Gigantic Promise

June 13, 2017

Figure 1. Conceptual schematic of Human-on-a-chip (Image credit: Wikipedia) “Currently worth a few million dollars, the emerging organs-on-a-chips market has the potential to become a multi-billion dollar market”, announces Sébastien [more...]

“Organs-On-Chips” Technology: FDA Testing Groundbreaking Science

April 12, 2017

Organ on a Chip (Image credit of Emulate) There are many things you might envision putting on a chip. It’s unlikely that a human organ is one of them. But creating human organ systems in miniature on micro-engineered chips about the size [more...]

A Tiny Reproductive System in a Dish Could Help us Understand Women’s Health

April 2, 2017

EVATAR is a female reproductive tract that fits in the palm of one’s hand. Each divided compartment within the cube contains a 3D model of a different part of the reproductive tract, such as the ovaries, fallopian tubes, uterus, cervix, [more...]

Researchers Develop Device That Emulates Human Kidney Function

February 18, 2017

This reusable, multi-layered and microfluidic device incorporates a porous growth substrate, with a physiological fluid flow, and the passive filtration of the capillaries around the end of a kidney, called the glomerulus, where waste is [more...]

Harvard Creating a Smoking Machine

November 27, 2016

In a published study, the Wyss Institute describes an instrument they engineered that can “breathe” in and out, actively smoke regular and electronic cigarettes much like a human. Individual mouth pieces in a rotating unit of the [more...]

3D-printed Heart-on-a-chip with Integrated Sensors

November 6, 2016

Harvard University researchers have made the first entirely 3D-printed organ-on-a-chip with integrated sensing. Built by a fully automated, digital manufacturing procedure, the 3D-printed heart-on-a-chip can be quickly fabricated and [more...]

Google Glass Meets Organs-on-Chips

March 25, 2016

Brigham and Women’s Hospital investigators have developed hardware and software to remotely monitor and control devices that mimic the human physiological system. Devices known as organs-on-chips allow researchers to test drug [more...]

A 3D-printed Organs-on-a-Chip Device Reveals Clues for Diabetes therapy

January 17, 2016

Figure 1. The device that contains three cell types mimics an endocrine and hormone transportation process. (Image Credit: Dr. Chengpeng Chen, Saint Louis University) A recent publication on the back cover of Integrative Biology achieved [more...]

Airway-on-a-Chip Models COPD and Asthma

January 2, 2016

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, such as chronic [more...]

2nd International Bioprinting Congress

July 9, 2015

Select Biosciences South East Asia is pleased to present the second annual International Bioprinting Congress, taking place at the Nanyang Executive Centre, Nanyang Technological University, Singapore on the 9-10 July 2015. Building on [more...]

Heartbeat On a Chip

June 21, 2015

Heartbeat Chip Test (Image credit: Michigan Engineering) The ability to accurately test drugs and therapies for human use is a goal we desperately need to reach. Often animals are used to test drugs intended for human use, which not only [more...]

Johnson & Johnson to Deploy Emulate' s Organs-on-Chips Platform in Drug Development Process

June 21, 2015

New Thrombosis-on-Chip (Image credit: EmulateBio) Emulate, whose president Geraldine Hamilton will speak at the first Organ-on-a-Chip World Congress 8-9 July 2015, said the alliance was intended to improve Janssen’s drug development [more...]

Researchers Design Placenta-on-a-chip To Better Understand Pregnancy

June 20, 2015

A placenta-on-a-chip microdevice: A) The device’s upper (blue) and lower (red) chambers are separated by a semi-permeable membrane. B) Researchers placed maternal cells in one chamber and fetal cells in the other. They then added glucose [more...]

Placenta-on-a-Chip: Universal Drug Testing Using Microfluidics

May 2, 2015

Placenta-on-a-chip prototype (Photo credit: Hashemi Lab from Iowa State University) Organ-on-a-chip technology is a rapidly growing segment within the field of microfluidics. These microscale chips combine cell biology with the [more...]

Hearts-on-a-chip Could Aid Drug Screening

March 9, 2015

UC Berkeley researchers have created a ‘heart-on-a-chip’ that effectively uses human cardiac muscle cells derived from adult stem cells to model how a human heart reacts to cardiovascular medications. The system could one day [more...]

Biodefence Researchers Seek Homo Chippiens

February 19, 2015

‘Organs on chips’, such as this simulated lung, could be used to test bodily responses to toxic chemicals (Image credit: Wyss Institute/Harvard) Each year, the US government spends hundreds of millions of dollars stockpiling [more...]