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On-Chip Sorting

China Develops Raman-activated Cell sorting and Sequencing System

December 27, 2018

Researchers at the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT) of the Chinese Academy of Sciences (Qingdao, China) have developed a Raman-activated cell sorting and sequencing (RACS-SEQ) instrument that enables [more...]

Microfluidic Chip Achieves High-speed Sorting of Large Cells

August 12, 2017

This microfluidic chip enables cell sorting in 16 μs; the enlarged view shows a demonstration of on-chip cell sorting of a Euglena gracilis cell (time interval of each frame: 40 μs). (Image copyright: Shinya Sakuma, Yusuke Kasai, Takeshi [more...]

IBM Lab-on-a-Chip Breakthrough Aims to Help Physicians Detect Cancer

August 2, 2016

A view of IBM’s lab-on-a-chip mounted in a microfluidic jig. IBM scientists have developed a new lab-on-a-chip technology that can, for the first time, separate biological particles at the nanoscale and could help enable physicians [more...]

New cell-sorting Technology Could Improve The Development Of Cell Therapies

March 21, 2016

Progressively spaced micropillars in the new magnetic ratcheting system for sorting cells (Credit: UCLA) Researchers at UCLA have developed a new way to separate and organize cells suspended in fluid samples by their subtle biochemical [more...]

An Optofluidic Chip for Single-cell Sorting Based on Mechanical Properties

November 29, 2015

A monolithic optofluidic chip fabricated by femtosecond laser extracts highly metastatic cells from a heterogeneous population on the basis of optical stretching measurements. The past decade has seen an increasing interest in the analysis [more...]

Holographic Imaging For Rapidly sorting Stem Cells, Cancer Cells

October 11, 2015

MIT scientists created these 3-D images of living cells based on measurements of their index of refraction. Different colors represent different indices of refraction, which correlate with the cells’ density, allowing for cells to be [more...]

A Fast Cell Sorter Shrinks to Cell Phone Size

September 22, 2015

Drawing of blood components being separated by sound waves (Image Image: Tony Jun Huang/Penn State) Commercial fluorescence activated cell sorters have been highly successful in the past 40 years at rapidly and accurately aiding medical [more...]

Flow Cytometry On-a-Chip

June 10, 2015

IT’S MAGNETIC: Hakho Lee’s CTC counter features eight micro-Hall elements (yellow crosses, above), staggered to maximize detection accuracy. (Photo Credit: D. ISSADORE ET AL.) Originally an immunology tool and a fixture of cell [more...]

What Makes Cancer Cells Spread? New Microfluidic Device Offers Clues

May 27, 2015

Individual cancer cells were isolated with a new device. The cell on the left is less likely to metastasize. Why do some cancer cells break away from a tumor and travel to distant parts of the body? A team of oncologists and engineers from [more...]

NanoCellect And Invetech Announce Collaboration To Develop Novel Flow Cytometry Platform

April 27, 2015

Microfluidic cell sorter (Image Credit: NanoCellect) Invetech, a global leader in instrument design and development, custom automation, and contract manufacturing, and NanoCellect Biomedical, a company developing affordable and accessible [more...]

Microfluidic Cell Sorting: A Review of the Advances in the Cell Seperation

February 21, 2015

Authors: C. Wyatt Shields IV, Catherine D. Reyes and Gabriel P. López from Duke University Accurate and high throughput cell sorting is a critical enabling technology in molecular and cellular biology, biotechnology, and medicine. [more...]

Sorting bloodborne cancer cells to better predict spread of disease

November 16, 2014

Devices that capture circulating tumor cells from the blood of cancer patients are currently in use, but they cannot differentiate among the different types of tumor cells. Cancer researchers and doctors are interested in methods that [more...]

Microfluidic Deformability-Based Cell Separation

November 2, 2014

Cell deformability is an important emerging bio-marker for a number of disease states. Deformability is indicative of underlying membrane, cytoskeletal or nuclear changes associated with a wide range of cell functional changes, such as [more...]

Downsize Your Cell Sorting with Microfluidics

September 2, 2014

Author: Josh P. Roberts Since the 1960s, cell sorters have enabled researchers to tease apart differences in cells’ immunological makeup and gene and protein expression. More recently, fluorescence activated cell sorting (FACS, [more...]

IMEC On-Chip Single Cell Sorter

August 27, 2014

Imagine a tool the size of a credit card that can analyze single cells with a throughput of more than 2 million cells per second. Moreover, the tool retains each cell of interest for downstream molecular analysis. The first steps towards [more...]

Sorting Cancer Cells with Acoustic Waves

August 27, 2014

Researchers from MIT, Pennsylvania State University, and Carnegie Mellon University have devised a new way to separate cells by exposing them to sound waves as they flow through a tiny channel. Their device, about the size of a dime, could [more...]