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Genomics

Cheap DNA Sequencing Is Here. Writing DNA Is Next

November 23, 2015

At Twist Bioscience’s office in San Francisco, CEO Emily Leproust pulled out of her tote bag two things she carries around everywhere: a standard 96-well plastic plate ubiquitous in biology labs and her company’s invention, a silicon [more...]

Irish Cattle Breeding Federation Selects Illumina

October 30, 2015

Next-generation sequencing (NGS) and genotyping technologies are revolutionizing animal breeding. Traditional animal breeding relies on scoring animals based on their observed physical characteristics (phenotype) to determine their [more...]

Single-Cell Proteomics Is in the Chips

July 28, 2015

At Northeastern University, researchers are developing ScanDrop, a lab-on-a-chip biosensor approach that utilizes a well-mixed microfluidic device and a microsphere-based assay capable of performing near real-time diagnostics. ScanDrop has [more...]

Single-Cell Analysis: Powerful Drops in the Bucket

June 8, 2015

If you’re curious what innovations are coming out of the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, take a look at this video shot via a microscope. What at first glance looks like water dripping [more...]

Measuring The Mass of Molecules on The Nanoscale

June 4, 2015

Coupled microcantilevers are placed on the XY-axis-stage and moved by the piezoelectric actuator according to the proposed feedback control to produce self-excited oscillation. Working with a device that slightly resembles a [more...]

Can We Identify Every Kind of Cell in the Body?

May 28, 2015

A microfluidic device (at center) can carry out experiments on individual cells (Image Credit: MIT Tech Review) How many types of cells are there in the human body? Textbooks say a couple of hundred. But the true number is undoubtedly far [more...]

New Platforms Genetically Barcode Tens of Thousands of Cells At a Time

May 27, 2015

Screenshot of microfluidic devices for genetically barcoding ( from: Harvard Medical School) Imagine someone hands you a smoothie and asks you to identify everything that went into it. You might be able to discern a hint of strawberry or [more...]

Weighing and Imaging Molecules One at a Time

May 8, 2015

Multimode nanoelectromechanical systems (NEMS) based mass sensor; the main figure schematically depicts a doubly-clamped beam vibrating in fundamental mode (1). Conceptual “snapshots” of the first six vibrational modes are shown below [more...]

Graphene for Nanopore-based DNA Sequencing

May 8, 2015

Fig.1 Optical and schematic images of a GFET device A research team led by Steven Prawer and Jiri Cervenka at the University of Melbourne, Australia fabricated a graphene field-effect transistor (GFET)—a layer of graphene atop a layer of [more...]

How Researchers, Breeders, and Farms Are Using Genomics to Improve Global Food Security?

May 7, 2015

Exponential population growth and changing climate patterns are creating unique challenges for the agriculture industry. To continue to address global food needs, many researchers, breeders, and farms are turning to genomics, or DNA [more...]

µParaflo® Microfluidic Synthesis Platform

April 6, 2015

µParaflo® microfluidic chip (Image Credit: LC Sciences) A requirement common for all targeted sequencing methods, whether hybridization capture based or multiplex PCR based is a need for large numbers of custom oligonucleotide primers [more...]