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Micro-devices for Drug Discovery

Skin Vaccination with Microneedle Patch

July 23, 2017

Biodegradable micro-needle patch (image credit: Georgia State University) A boosting skin vaccination with a biodegradable microneedle patch and protein constructed from sequences of influenza virus subtypes could improve the effectiveness [more...]

Microflow Sensor, Micropump Combine for Single-use Drug Delivery Module

March 28, 2017

Fraunhofer EMFT’s silicon micropump has been combined with Sensirion’s LD20 single-use liquid flow sensor to develop a smart and cost-efficient miniaturized module for controlled and monitored drug delivery. This highly integrated [more...]

FDA OKs Insulin Pump Plus Glucose Monitor System

March 26, 2017

The FDA has approved Medtronic’s new diabetes management system, which takes patients one step closer to the elusive goal of an artificial pancreas. The new MiniMed Paradigm REAL-Time Revel System does not entirely close the loop [more...]

Microneedles: a Painless Way to Monitor Drug Concentrations in the Bloodstream

August 1, 2016

Figure Cross-sectional schematic view (A) and top view design (B) of the devices. A surface-functionalized microneedle is integrated to a PDMS optofluidic device equipped with optical fibers. The mechanism of the optical waveguide equipped [more...]

Microneedle Patch Delivers Localized Immunotherapy to Melanoma

March 30, 2016

Biomedical engineering researchers at North Carolina State University and the University of North Carolina at Chapel Hill have developed a technique that uses a patch embedded with microneedles to deliver cancer immunotherapy treatment [more...]

Dime-Sized Electric Chip Removes Nanoparticles from Blood with Ease

November 25, 2015

An artist’s representation of the nanoparticle removal chip developed by researchers in Professor Michael Heller’s lab at the UC San Diego Jacobs School of Engineering. An oscillating electric field (purple arcs) separates [more...]

Implantable Insulin Pump Now Possible With MEMs Technology

November 15, 2015

MEMS TECHNOLOGY Would you use an implantable insulin Pump? Debiotech is a medical device company, based in Switzerland. The development of innovative medical tech is their main business and, since its inception, the company designed many [more...]

Drug Delivery On The Go: Device Design Considerations

November 3, 2015

Wearable devices are changing the world of drug delivery, emerging as solutions for chronic disease management and offering patients reprieve from the burden associated with frequent injections and bulky ambulatory devices. Diabetes care [more...]

Pharma and Drug Delivery Developments Combine

October 11, 2015

Both micro manufacturing techniques and materials advancements are constantly driving innovation in pharmaceutical devices, combination devices, and drug delivery. The medical device sector is constantly pushing the drive towards [more...]

Microchips Biotech Commercializes Implantable Drug-delivery Device

June 29, 2015

A version of Microchip Biotech’s implantable, wirelessly controlled microchip. When an electrical current is delivered to one of the chip’s tiny reservoirs, a single dose of therapeutics is released into the body. (Image [more...]

Ion Pump Implant Gives the Body Its Own Pain Alleviation

May 17, 2015

The device consists of an electronically and ionically conducting polymer electrode inside a fluid reservoir, and an ionically conducting delivery channel leading out to the target region—for example, the spinal cord. The reservoir is [more...]

An Electronic Micropump to Deliver Treatments deep Within The Brain

April 27, 2015

The organic electronic micropump (represented by a purple cylinder) directly releases among the neurons, active molecules (spheres) that will control the activity of these neurons (here they will stop the epileptic activity). Many [more...]

Researchers Deliver Large Particles into Cells at High Speed

April 9, 2015

A team led by Professor Eric Pei-Yu Chiou created a tool that delivers nanoparticles, enzymes, antibodies and bacteria into cells at the rate of 100,000 cells per minute — significantly faster than current technology. A new device [more...]

New Nanoneedles Could Be an Important Tool to Reprogram Cells

April 4, 2015

Image of nanoneedles delivering nucleic acids to a human cell (Image Credit:Imperial College London) Researchers from Imperial College London think that a new nanoneedle technique could help deliver nucleic acids to cells. This would then [more...]

Exotic Micropumps and Gels Offer Hope for Hearing Disorders

March 14, 2015

Researchers at the Charles Stark Draper Laboratory have fabricated and tested a simplified micropump and used it to demonstrate the flow of fluid into and out of the device, the ability to store drug in a reservoir on board, and the [more...]

Microfluidics Enables Production of Shape-controllable Microgels

February 11, 2015

The schematic on top depicts a microfluidic device to create biocompatible particles called shape-controllable microgels that could be custom designed for specific roles such as drug delivery vehicles, tissue engineering building blocks [more...]

Novel Microfluidic Device Allows Electroporation of Stem Cells During Differentiation

January 20, 2015

Photo credit: Prof. Horacio D. Espinosa and Prof. John A. Kessler at Northwestern University, USA. Electroporation is a powerful technique in molecular biology. By using an electrical pulse to create a temporary nanopore in a cell [more...]

CellSqueeze microfluidic chips

December 10, 2014

Intracellular delivery of macromolecules has long been a challenge in both research and therapeutic applications. Prof. Klavs Jensen and Prof. Robert Langer of MIT recognized this challenge and organized a collaborative research effort to [more...]

Nanomotor in Drug Delivery Application

October 13, 2014

Researchers at the Cockrell School of Engineering at The University of Texas at Austin say they have built the smallest, fastest and longest-running synthetic motor to date. The nanomotor is a step toward developing miniature machines [more...]

Applications of Graphene in Medicine, including Microfluidics

October 9, 2014

With exceptional electrical, optical, mechanical and chemical properties, Graphene was deemed a wonder material upon its fabrication in Manchester, UK in 2004. It is comprised solely of carbon, bonded in a hexagonal honeycomb structure in [more...]