Sequencing

Single Cell Sequencing Sheds Light on Why Cancers Form in Specific Cell Types

November 30, 2018

While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tumors arise when a mutation happens in a [more...]

Single-nucleus RNA sequencing, Droplet by Droplet

September 4, 2017

Image Credit : Susanna M. Hamilton, Broad Communications Last year Broad researchers described a single-nucleus RNA sequencing method called sNuc-Seq. This system enabled researchers to study the gene expression profiles of [more...]

A Review of Droplet-Sequencing

May 14, 2017

Cells, the building blocks of tissues, organs, and organisms, vary broadly in type and state. Today, the lack of information about cellular diversity in complex tissues leads researchers to find new ways of single-cell analysis and [more...]

Review: Microfluidics Solution to Future Developments

August 15, 2015

Cell encapsulation with Dolomite microfluidic device. (Image Credit: Dolomite Microfluidics) Interest in microfluidics technology began as far back at 1975, when researchers at Stanford Univ. developed a miniature gas chromatograph [more...]

Graphene for Nanopore-based DNA Sequencing

May 8, 2015

Fig.1 Optical and schematic images of a GFET device A research team led by Steven Prawer and Jiri Cervenka at the University of Melbourne, Australia fabricated a graphene field-effect transistor (GFET)—a layer of graphene atop a layer of [more...]